Analysis of a membrane‐enriched proteome from postmortem human brain tissue in Alzheimer's disease

No abstract is available for this paper.

• Publication year

  2012

• Venue

  PROTEOMICS - Clinical Applications

• Publication date

  2012-04-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1002/prca.201100068PMID 22532456PMCID PMC3338199
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Alzheimer's disease.

  2011cited by this paper
• 2011 Alzheimer's disease facts and figures

  2011cited by this paper
• Identification and preliminary characterization of ubiquitin C terminal hydrolase 1 (UCHL1) as a biomarker of neuronal loss in aneurysmal subarachnoid hemorrhage

  2010cited by this paper
• National Institutes of Health State-of-the-Science Conference Statement: Preventing Alzheimer Disease* and Cognitive Decline

  2010cited by this paper
• Ubiquitin carboxy-terminal hydrolase L1 (UCHL1) S18Y polymorphism in Alzheimer's disease

  2010cited by this paper
• Phosphoproteomic analysis reveals site-specific changes in GFAP and NDRG2 phosphorylation in frontotemporal lobar degeneration.

  2010cited by this paper
• Super-SILAC mix for quantitative proteomics of human tumor tissue

  2010cited by this paper
• Rho Kinase II Phosphorylation of the Lipoprotein Receptor LR11/SORLA Alters Amyloid-β Production*

  2010cited by this paper
• Amyloid-Independent Mechanisms in Alzheimer's Disease Pathogenesis

  2010cited by this paper
• Quantitative Changes in the Mitochondrial Proteome from Subjects with Mild Cognitive Impairment, Early Stage, and Late Stage Alzheimer's Disease

  2010cited by this paper
• Vesicle Fusion Probability Is Determined by the Specific Interactions of Munc18*

  2010cited by this paper
• Ubiquitin carboxyl-terminal hydrolase L1 (UCHL1) regulates the level of SMN expression through ubiquitination in primary spinal muscular atrophy fibroblasts.

  2010cited by this paper
• Dendritic function of tau mediates amyloid-beta toxicity in Alzheimer's disease mouse models.

  2010cited by this paper
• UCHL1 (PGP 9.5): neuronal biomarker and ubiquitin system protein.

  2010cited by this paper
• Membrane-associated farnesylated UCH-L1 promotes α-synuclein neurotoxicity and is a therapeutic target for Parkinson's disease

  2009cited by this paper
• Proteomics analysis reveals novel components in the detergent-insoluble subproteome in Alzheimer's disease.

  2009cited by this paper
• World Alzheimer Report 2009

  2009cited by this paper
• Systematical optimization of reverse-phase chromatography for shotgun proteomics.

  2009cited by this paper
• Proteomic identification of novel proteins associated with Lewy bodies.

  2008cited by this paper
• Biomarker discovery: proteome fractionation and separation in biological samples.

  2008cited by this paper
• Phosphoproteomic analysis of human brain by calcium phosphate precipitation and mass spectrometry.

  2008cited by this paper
• Systematic approach for validating the ubiquitinated proteome.

  2008cited by this paper
• Determination of protein-RNA interaction sites in the Cbf5-H/ACA guide RNA complex by mass spectrometric protein footprinting.

  2008cited by this paper
• Up-regulation of NG2 proteoglycan and interferon-induced transmembrane proteins 1 and 3 in mouse astrocytoma: a membrane proteomics approach.

  2008cited by this paper
• Quantitative proteomics of intracellular Porphyromonas gingivalis

  2007cited by this paper
• Quantitative mass spectrometry in proteomics: a critical review

  2007cited by this paper
• Differential quantitative proteomics of Porphyromonas gingivalis by linear ion trap mass spectrometry: non-label methods comparison, q-values and LOWESS curve fitting.

  2007cited by this paper
• Munc18-2 regulates exocytotic membrane fusion positively interacting with syntaxin-3 in RBL-2H3 cells.

  2007cited by this paper
• Quantitative Proteomics of the Archaeon Methanococcus maripaludis Validated by Microarray Analysis and Real Time PCR *S

  2006cited by this paper
• Global survey of organ and organelle protein expression in mouse: combined proteomic and transcriptomic profiling.

  2006cited by this paper
• A Century of Alzheimer's Disease

  2006cited by this paper
• Cyclin-dependent kinase 5, Munc18a and Munc18-interacting protein 1/X11alpha protein up-regulation in Alzheimer's disease.

  2006cited by this paper
• Alzheimer's disease

  2006cited by this paper
• Mitochondrial creatine kinase in human health and disease.

  2006cited by this paper
• Comparison of Label-free Methods for Quantifying Human Proteins by Shotgun Proteomics*S

  2005cited by this paper
• Quantitative mouse brain proteomics using culture-derived isotope tags as internal standards

  2005cited by this paper
• Neuropathological stageing of Alzheimer-related changes

  2004cited by this paper
• Genetic causes of Parkinson’s disease: UCHL-1

  2004cited by this paper
• Oxidative Modifications and Down-regulation of Ubiquitin Carboxyl-terminal Hydrolase L1 Associated with Idiopathic Parkinson's and Alzheimer's Diseases*

  2004cited by this paper
• Neuroproteomics: Expression Profiling of the Brain's Proteomes in Health and Disease

  2004cited by this paper
• Genetic association of Alzheimer's disease with multiple polymorphisms in alpha-2-macroglobulin.

  2003cited by this paper
• A role for Mints in transmitter release: Mint 1 knockout mice exhibit impaired GABAergic synaptic transmission

  2003influential reference
• Evaluation of multidimensional chromatography coupled with tandem mass spectrometry (LC/LC-MS/MS) for large-scale protein analysis: the yeast proteome.

  2003cited by this paper
• Mass spectrometry-based proteomics

  2003cited by this paper
• Stable Isotope Labeling by Amino Acids in Cell Culture, SILAC, as a Simple and Accurate Approach to Expression Proteomics*

  2002cited by this paper
• The UCH-L1 gene encodes two opposing enzymatic activities that affect-synuclein degradation and Park

  2002cited by this paper
• The UCH-L1 gene encodes two opposing enzymatic activities that affect alpha-synuclein degradation and Parkinson's disease susceptibility.

  2002cited by this paper
• Proteomics: the move to mixtures.

  2001cited by this paper
• Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes.

  2001cited by this paper
• Interaction of Tau with the Neural Membrane Cortex Is Regulated by Phosphorylation at Sites That Are Modified in Paired Helical Filaments*

  2000cited by this paper
• Genetic association of an alpha2-macroglobulin (Val1000lle) polymorphism and Alzheimer's disease.

  1998cited by this paper
• Alpha-2 macroglobulin is genetically associated with Alzheimer disease

  1998cited by this paper
• Genetic association of an (α2-macroglobulin (Val1000lle) polymorphism and Alzheimer's disease

  1998cited by this paper
• Alpha2-macroglobulin complexes with and mediates the endocytosis of beta-amyloid peptide via cell surface low-density lipoprotein receptor-related protein.

  1997cited by this paper
• α2‐Macroglobulin Complexes with and Mediates the Endocytosis of β‐Amyloid Peptide via Cell Surface Low‐Density Lipoprotein Receptor‐Related Protein

  1997cited by this paper
• Interaction of tau with the neural plasma membrane mediated by tau's amino-terminal projection domain

  1995cited by this paper
• Alzheimer's disease: the amyloid cascade hypothesis.

  1992cited by this paper
• A68: a major subunit of paired helical filaments and derivatized forms of normal Tau.

  1991cited by this paper
• The Consortium to Establish a Registry for Alzheimer's Disease (CERAD)

  1991cited by this paper
• Alzheimerʼs disease: initial report of the purification and characterization of a novel cerebrovascular amyloid protein

  1988cited by this paper
• Amyloid plaque core protein in Alzheimer disease and Down syndrome.

  1985cited by this paper
• Handbook of Neurochemistry

  1983cited by this paper

• Membrane Proteome Remodeling in Female APP Mice Following Muscarinic Acetylcholine Receptor M1 Modulation Revealed by Peptidisc Enabled DIA-MS

  2026cites this paper
• Tau oligomers modulate synapse fate by eliciting progressive bipartite synapse dysregulation and synapse loss

  2025cites this paper
• The omics techniques used in perineuronal nets research.

  2025cites this paper
• UCH-L1 in Alzheimer’s Disease: A Crucial Player in Dementia-Associated Mechanisms

  2025cites this paper
• Network Medicine Approach Unravels Endophenotype Signature in Alzheimer's Disease through Large-Scale Comparative Proteomics Analysis: Vascular Dysfunction as a Prime Example

  2024cites this paper
• Elevated Cerebrospinal Fluid Ubiquitin Carboxyl‐Terminal Hydrolase Isozyme L1 in Asymptomatic C9orf72 Hexanucleotide Repeat Expansion Carriers

  2024cites this paper
• Subcellular proteomics insights into Alzheimer's disease development

  2023cites this paper
• Data‐independent acquisition proteomics of cerebrospinal fluid implicates endoplasmic reticulum and inflammatory mechanisms in amyotrophic lateral sclerosis

  2023cites this paper
• Compilation of reported protein changes in the brain in Alzheimer’s disease

  2023cites this paper
• The amyloid plaque proteome in early onset Alzheimer’s disease and Down syndrome

  2022cites this paper
• Proteomics Landscape of Alzheimer’s Disease

  2021cites this paper
• Role of Munc18-1 in the biological functions and pathogenesis of neurological disorders

  2021cites this paper
• Apolipoprotein E proteinopathy is a major dementia-associated pathologic biomarker in individuals with or without the APOE epsilon 4 allele.

  2021cites this paper
• Characterization of functional protein complexes from Alzheimer’s disease and healthy brain by mass spectrometry-based proteome analysis

  2021cites this paper
• Syntaxin Binding Protein 1 Related Epilepsies

  2021cites this paper
• Sequence of proteome profiles in preclinical and symptomatic Alzheimer's disease

  2021cites this paper
• Historical Overview of Integrated GAG-omics and Proteomics

  2020cites this paper
• Much More Than a Cytoskeletal Protein: Physiological and Pathological Functions of the Non-microtubule Binding Region of Tau

  2020cites this paper
• Serial in-solution digestion protocol for mass spectrometry-based glycomics and proteomics analysis.

  2020cites this paper
• Ubiquitin carboxy‐terminal hydrolase L1 – physiology and pathology

  2020cites this paper
• Arginine π-stacking drives binding to fibrils of the Alzheimer protein Tau

  2020cites this paper
• Extracellular Matrix Omics

  2020cites this paper
• Alzheimer Cells on Their Way to Derailment Show Selective Changes in Protein Quality Control Network

  2020cites this paper
• Using Proteomics to Understand Alzheimer’s Disease Pathogenesis

  2019cites this paper
• Fibril formation rewires interactome of the Alzheimer protein Tau by π-stacking

  2019cites this paper
• Network Analysis of a Membrane-Enriched Brain Proteome across Stages of Alzheimer’s Disease

  2019influential citation
• Increased expression of heme-binding protein 1 early in Alzheimer's disease is linked to neurotoxicity

  2019cites this paper
• Alcohol Drinking Exacerbates Neural and Behavioral Pathology in the 3xTg-AD Mouse Model of Alzheimer’s Disease

  2019cites this paper
• Postsynaptic Proteome of Non-Demented Individuals with Alzheimer’s Disease Neuropathology

  2018cites this paper
• Quantitative Analysis of the Brain Ubiquitylome in Alzheimer's Disease

  2018cites this paper
• Mechanism-based rescue of Munc18-1 dysfunction in varied encephalopathies by chemical chaperones

  2018cites this paper
• Proteomic-based Signature of Brain-related Proteins as Novel Candidate Biomarkers for Alzheimer’s Disease Diagnosis

  2018cites this paper
• Autophagy and Alzheimer’s Disease: From Molecular Mechanisms to Therapeutic Implications

  2018cites this paper
• Characterization of Detergent Insoluble Proteome in Chronic Traumatic Encephalopathy

  2018cites this paper
• Regional protein expression in human Alzheimer’s brain correlates with disease severity

  2018cites this paper
• Proteomics of neurodegenerative diseases: analysis of human post‐mortem brain

  2018cites this paper
• Potential Novel Approaches to Understand the Pathogenesis and Treat Alzheimer’s Disease

  2018cites this paper
• Detergent Insoluble Proteins and Inclusion Body-Like Structures Immunoreactive for PRKDC/DNA-PK/DNA-PKcs, FTL, NNT, and AIFM1 in the Amygdala of Cognitively Impaired Elderly Persons

  2018cites this paper
• Proteomic differences in amyloid plaques in rapidly progressive and sporadic Alzheimer’s disease

  2017cites this paper
• Hippocampal Proteomic Analysis Reveals Distinct Pathway Deregulation Profiles at Early and Late Stages in a Rat Model of Alzheimer’s-Like Amyloid Pathology

  2017cites this paper
• The Triangle of Death in Alzheimer's Disease Brain: The Aberrant Cross-Talk Among Energy Metabolism, Mammalian Target of Rapamycin Signaling, and Protein Homeostasis Revealed by Redox Proteomics

  2017cites this paper
• Recent advances in applying mass spectrometry and systems biology to determine brain dynamics

  2017cites this paper
• Recent progress in mass spectrometry proteomics for biomedical research

  2017cites this paper
• Extracellular matrix proteomics in schizophrenia and Alzheimer’s disease

  2016cites this paper
• Analysis of the Cerebrospinal Fluid Proteome in Alzheimer's Disease

  2016cites this paper
• Changes in the detergent‐insoluble brain proteome linked to amyloid and tau in Alzheimer's Disease progression

  2016cites this paper
• Ubiquitin C-terminal hydrolase L1 (UCH-L1): structure, distribution and roles in brain function and dysfunction

  2016cites this paper
• Karyopherin Alpha 1 Regulates Satellite Cell Proliferation and Survival by Modulating Nuclear Import

  2016cites this paper
• Munc18-1 is a molecular chaperone for α-synuclein, controlling its self-replicating aggregation

  2016cites this paper
• Alzheimer's disease: are blood and brain markers related? A systematic review

  2016cites this paper
• Rho‐associated protein kinase 1 (ROCK1) is increased in Alzheimer's disease and ROCK1 depletion reduces amyloid‐β levels in brain

  2016cites this paper
• Brain quantitative proteomic responses reveal new insight of benzotriazole neurotoxicity in female Chinese rare minnow (Gobiocypris rarus).

  2016cites this paper
• UNDERSTANDING PHYSIOLOGY OF DISEASES AND CELL LINES USING OMICS BASED APPROACHES

  2015cites this paper
• PROTEIN-PROTEIN INTERACTION NETWORK OF ALZHEIMER'S DISEASE FROM HUMAN HIPPOCAMPAL PROTEOME

  2015cites this paper
• Proteomic analysis of neurons microdissected from formalin-fixed, paraffin-embedded Alzheimer’s disease brain tissue

  2015cites this paper
• NH 2-truncated human tau induces deregulated mitophagy in neurons by aberrant recruitment of Parkin and UCHL-1 : implications in Alzheimer ’ s disease

  2015cites this paper
• Loss of Munc18-1 long splice variant in GABAergic terminals is associated with cognitive decline and increased risk of dementia in a community sample

  2015cites this paper
• Neurodegeneration and Alzheimer's disease (AD). What Can Proteomics Tell Us About the Alzheimer's Brain?*

  2015cites this paper
• NH2-truncated human tau induces deregulated mitophagy in neurons by aberrant recruitment of Parkin and UCHL-1: implications in Alzheimer's disease.

  2015cites this paper
• Neuroproteomics tools in clinical practice.

  2015cites this paper
• Coupling enrichment methods with proteomics for understanding and treating disease

  2015cites this paper
• Proteomics in neurodegenerative diseases: Methods for obtaining a closer look at the neuronal proteome

  2015cites this paper
• Explorative and targeted neuroproteomics in Alzheimer's disease.

  2015cites this paper
• Mass Spectrometry-Based Investigation of APP-Dependent Mechanisms in Neurodegeneration

  2015cites this paper
• Neuroinformatic analyses of common and distinct genetic components associated with major neuropsychiatric disorders

  2014cites this paper
• Role of proteomics in biomarker discovery: prognosis and diagnosis of neuropsychiatric disorders.

  2014cites this paper
• Pharmacologic Inhibition of ROCK2 Suppresses Amyloid-β Production in an Alzheimer's Disease Mouse Model

  2013cites this paper
• Glia-based biomarkers and their functional role in the CNS

  2013cites this paper
• Review: Activation patterns of microglia and their identification in the human brain

  2013cites this paper
• Neuron enriched nuclear proteome isolated from human brain.

  2013cites this paper
• Two Novel Tau Antibodies Targeting the 396/404 Region Are Primarily Taken Up by Neurons and Reduce Tau Protein Pathology*

  2013cites this paper
• Recent advances in quantitative neuroproteomics.

  2013cites this paper
• Quantitative proteomics for identifying biomarkers for Rabies

  2013cites this paper
• Early events in the onset of type II diabetes : effects of aggregated amylin (IAPP) on the islet proteome and metabolic pathways

  2013cites this paper
• U1 small nuclear ribonucleoprotein complex and RNA splicing alterations in Alzheimer’s disease

  2013cites this paper
• Semiquantitative proteomic analysis of human hippocampal tissues from Alzheimer’s disease and age-matched control brains

  2013cites this paper
• Exploring the potential of the platelet membrane proteome as a source of peripheral biomarkers for Alzheimer's disease

  2013cites this paper
• Interaction between misfolded PrP and the ubiquitin-proteasome system in prion-mediated neurodegeneration.

  2013cites this paper
• Revista Brasileira de Psiquiatria

  2012cites this paper
• Novos alvos moleculares para tomografia por emissão de pósitrons (PET) e tomografia computadorizada por emissão de fóton único (SPECT) em doenças neurodegenerativas

  2012cites this paper
• New molecular targets for PET and SPECT imaging in neurodegenerative diseases.

  2012cites this paper