Ca(2+) entry through L-type Ca(2+) channels helps terminate epileptiform activity by activation of a Ca(2+) dependent afterhyperpolarisation in hippocampal CA3.

No abstract is available for this paper.

• Publication year

  2001

• Venue

  Neuroscience

• Publication date

  2001-01-15

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1016/S0306-4522(00)00494-2PMID 11166116
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Suppression of epileptiform burst discharges in CA3 neurons of rat hippocampal slices by the organic calcium channel blocker, verapamil

  2004cited by this paper
• Functional phenotype in transgenic mice expressing mutant human presenilin-1.

  2000cited by this paper
• Novel action of BAPTA series chelators on intrinsic K+ currents in rat hippocampal neurones

  2000cited by this paper
• Contribution of L-type calcium channels to epileptiform activity in hippocampal and neocortical slices of guinea-pigs.

  1999cited by this paper
• Apamin-sensitive conductance mediates the K(+) current response during chemical ischemia in CA3 pyramidal cells.

  1999cited by this paper
• Ca2+ channels that activate Ca2+-dependent K+ currents in neostriatal neurons.

  1999cited by this paper
• Intrinsic physiological and morphological properties of principal cells of the hippocampus and neocortex in hamsters infected with scrapie.

  1999cited by this paper
• GABA(B) receptor activation promotes seizure activity in the juvenile rat hippocampus.

  1999cited by this paper
• A relative energy failure is associated with low-Mg2+ but not with 4-aminopyridine induced seizure-like events in entorhinal cortex.

  1999cited by this paper
• Synaptic reorganization in explanted cultures of rat hippocampus.

  1999cited by this paper
• Photolytic Manipulation of [Ca2+]iReveals Slow Kinetics of Potassium Channels Underlying the Afterhyperpolarization in Hipppocampal Pyramidal Neurons

  1999cited by this paper
• Seizure-like events in disinhibited ventral slices of adult rat hippocampus.

  1999cited by this paper
• An apamin-sensitive Ca2+-activated K+ current in hippocampal pyramidal neurons.

  1999cited by this paper
• Specificity in the interaction of HVA Ca2+ channel types with Ca2+-dependent AHPs and firing behavior in neocortical pyramidal neurons.

  1998cited by this paper
• Mechanism of calcium gating in small-conductance calcium-activated potassium channels

  1998cited by this paper
• Electrical and calcium signaling in dendrites of hippocampal pyramidal neurons.

  1998cited by this paper
• L-Type Ca2+ channels mediate the slow Ca2+-dependent afterhyperpolarization current in rat CA3 pyramidal cells in vitro.

  1998cited by this paper
• Calcium-activated potassium channels.

  1998cited by this paper
• Participation of GABAA-mediated inhibition in ictallike discharges in the rat entorhinal cortex.

  1998cited by this paper
• Selective activation of Ca2+-activated K+ channels by co-localized Ca2+ channels in hippocampal neurons

  1998cited by this paper
• Spatiotemporal distribution of intracellular calcium transients during epileptiform activity in guinea pig hippocampal slices.

  1997cited by this paper
• CA3-Driven Hippocampal-Entorhinal Loop Controls Rather than Sustains In Vitro Limbic Seizures

  1997cited by this paper
• Ca(2+)-activated K+ currents in neurones: types, physiological roles and modulation.

  1996cited by this paper
• On the Structure of Ictal Events in Vitro

  1996cited by this paper
• Reversible inhibition of IK, IAHP, Ih and ICa currents by internally applied gluconate in rat hippocampal pyramidal neurones

  1996cited by this paper
• Small-Conductance, Calcium-Activated Potassium Channels from Mammalian Brain

  1996cited by this paper
• Potentiation of a slow Ca(2+)-dependent K+ current by intracellular Ca2+ chelators in hippocampal CA1 neurons of rat brain slices.

  1995cited by this paper
• Dendritic calcium transients evoked by single back‐propagating action potentials in rat neocortical pyramidal neurons.

  1995cited by this paper
• Physiology and pharmacology of unitary synaptic connections between pairs of cells in areas CA3 and CA1 of rat hippocampal slice cultures.

  1995cited by this paper
• The excitability of CA1 pyramidal cell dendrites is modulated by a local Ca(2+)-dependent K(+)-conductance.

  1995cited by this paper
• Enhanced NMDA conductance can account for epileptiform activity induced by low Mg2+ in the rat hippocampal slice.

  1994cited by this paper
• Role of excitatory amino acid and GABAB receptors in the generation of epileptiform activity in disinhibited hippocampal slice cultures.

  1994cited by this paper
• Picrotoxin-induced epileptic activity in hippocampal and neocortical slices (guinea pig): suppression by organic calcium channel blockers.

  1994cited by this paper
• Characterization of Ca2+ signals induced in hippocampal CA1 neurones by the synaptic activation of NMDA receptors.

  1993cited by this paper
• Nimodipine increases excitability of rabbit CA1 pyramidal neurons in an age- and concentration-dependent manner.

  1992cited by this paper
• A simple method for organotypic cultures of nervous tissue.

  1991cited by this paper
• [Calcium-activated potassium channels].

  1985cited by this paper
• Intracellular calcium accumulation in rat hippocampus during seizures induced by bicuculline or L-allylglycine.

  1983cited by this paper
• Cellular mechanism of neuronal synchronization in epilepsy.

  1982cited by this paper
• Epileptiform burst afterhyperolarization: calcium-dependent potassium potential in hippocampal CA1 pyramidal cells.

  1980cited by this paper
• Effects of EGTA on the calcium-activated afterhyperpolarization in hippocampal CA3 pyramidal cells.

  1980cited by this paper
• Ionic changes during experimentally induced seizure activity.

  1978cited by this paper

• Calcium-Activated Potassium Channel KCa3.1 Shape Epileptiform Discharges in the Rodent Entorhinal Cortex

  2025cites this paper
• Insertion of Calcium-Permeable AMPA Receptors during Epileptiform Activity In Vitro Modulates Excitability of Principal Neurons in the Rat Entorhinal Cortex

  2021cites this paper
• L-type Ca2+ channels and charybdotoxin-sensitive Ca2+-activated K+ channels are required for reduction of GABAergic activity induced by β2-adrenoceptor in the prefrontal cortex.

  2019cites this paper
• Switching between persistent firing and depolarization block in individual rat CA1 pyramidal neurons

  2019influential citation
• Understanding the Generation of Network Bursts by Adaptive Oscillatory Neurons

  2018cites this paper
• L-type voltage-gated calcium channel regulation of in vitro human cortical neuronal networks

  2018cites this paper
• The creation of a platform for investigating the network function of human pluripotent stem cell derived neurons in development and disease

  2017cites this paper
• SK channels participate in the formation of after burst hyperpolarization and partly inhibit the burst strength of epileptic ictal discharges

  2017cites this paper
• Potential functional and pathological side effects related to off-target pharmacological activity.

  2017cites this paper
• Persistent firing and depolarization block in rat CA1 pyramidal neurons

  2016cites this paper
• Calcium Channels Hippocampus CA1 Region by Modulating L-Type Neurotensin Enhances GABAergic Activity in Rat

  2015cites this paper
• Small-conductance Ca2+-activated K+ channels modulate action potential-induced Ca2+ transients in hippocampal neurons.

  2013cites this paper
• Utilizing C. elegans as a neurological model to characterize KCNL-2, an SK channel homologue

  2013cites this paper
• A Small Conductance Calcium-Activated K+ Channel in C. elegans, KCNL-2, Plays a Role in the Regulation of the Rate of Egg-Laying

  2013cites this paper
• The Slow Afterhyperpolarization: A Target of β1-Adrenergic Signaling in Hippocampus-Dependent Memory Retrieval

  2013cites this paper
• A Sodium-Pump-Mediated Afterhyperpolarization in Pyramidal Neurons

  2013cites this paper
• Muscarinic receptor activation determines the effects of store-operated Ca(2+)-entry on excitability and energy metabolism in pyramidal neurons.

  2012cites this paper
• Network excitability in a model of chronic temporal lobe epilepsy critically depends on SK channel-mediated AHP currents.

  2012cites this paper
• Electrophysiological and Structural Aspects in the Frontal Cortex After the Bee (Apis mellifera) Venom Experimental Treatment

  2011cites this paper
• Upregulation of STREX splice variant of the large conductance Ca2+-activated potassium (BK) channel in a rat model of mesial temporal lobe epilepsy.

  2011cites this paper
• Evaluation of Candidate Genes from Orphan FEB and GEFS+ Loci by Analysis of Human Brain Gene Expression Atlases

  2011cites this paper
• Network Excitability Dysfunction in Alzheimer's Disease: Insights from In Vitro and In Vivo Models

  2010cites this paper
• Burst firing induces postsynaptic LTD at developing mossy fibre–CA3 pyramid synapses

  2009cites this paper
• Cortical hyperexcitability and epileptogenesis: understanding the mechanisms of epilepsy - part 1.

  2009cites this paper
• Calcium involvement in regulation of neuronal bursting in disinhibited neuronal networks: insights from calcium studies in a spherical cell model.

  2009cites this paper
• Molecular and cellular basis of small- and intermediate-conductance, calcium-activated potassium channel function in the brain

  2008cites this paper
• Neurotensin enhances GABAergic activity in rat hippocampus CA1 region by modulating L-type calcium channels.

  2008cites this paper
• The sigma‐1 receptor modulates NMDA receptor synaptic transmission and plasticity via SK channels in rat hippocampus

  2007cites this paper
• K+ M‐Current Regulates the Transition to Seizures in Immature and Adult Hippocampus

  2007influential citation
• The slow afterhyperpolarization modulates high pH‐induced changes in the excitability of rat CA1 pyramidal neurons

  2007cites this paper
• Calcium-activated afterhyperpolarizations regulate synchronization and timing of epileptiform bursts in hippocampal CA3 pyramidal neurons.

  2006cites this paper
• Subtype-specific, bi-component inhibition of SK channels by low internal pH.

  2006cites this paper
• In vivo characterisation of the small-conductance KCa (SK) channel activator 1-ethyl-2-benzimidazolinone (1-EBIO) as a potential anticonvulsant.

  2006cites this paper
• Increased Seizure Susceptibility of the Hippocampus Compared with the Neocortex of the Immature Mouse Brain in vitro

  2005cites this paper
• 1-Ethyl-2-benzimidazolinone (EBIO) suppresses epileptiform activity in in vitro hippocampus.

  2005cites this paper
• Inhibition modifies the effects of slow calcium-activated potassium channels on epileptiform activity in a neuronal network model

  2005cites this paper
• Activation of SK channels inhibits epileptiform bursting in hippocampal CA3 neurons.

  2005cites this paper
• Mitochondrial Calcium Ion and Membrane Potential Transients Follow the Pattern of Epileptiform Discharges in Hippocampal Slice Cultures

  2005cites this paper
• Cholinergic modulation of status epilepticus in the rat barrel field region of primary somatosensory cortex.

  2005cites this paper
• Model of frequent, recurrent, and spontaneous seizures in the intact mouse hippocampus

  2004cites this paper
• Comparison of neuroplastin and synaptic marker protein expression in acute and cultured organotypic hippocampal slices from rat.

  2004cites this paper
• Reduction of human neocortical and guinea pig CA1-neuron A-type currents by organic calcium channel blockers.

  2004cites this paper
• Pathophysiology of childhood epilepsies

  2004cites this paper
• Expression of plasma membrane Ca2+ ATPase family members and associated synaptic proteins in acute and cultured organotypic hippocampal slices from rat.

  2004cites this paper
• Reduction of intracellular calcium removal rate can explain changes in seizure dynamics: studies in neuronal network models.

  2003cites this paper
• Modulation of Cortical Nitric Oxide Synthase, Glutamate, and Redox State by Nifedipine and Taurine in PTZ‐kindled Mice

  2003cites this paper
• Background potassium concentrations and epileptiform discharges. II. Involvement of calcium channels.

  2003cites this paper
• Background potassium concentrations and epileptiform discharges. I. Electrophysiological characteristics of neuronal activity.

  2003cites this paper
• The Influence of Slow Calcium-Activated Potassium Channels on Epileptiform Activity in a Neuronal Model of Pyramidal Cells

  2003cites this paper
• Regulation of epileptiform activity in hippocampus by nicotinic acetylcholine receptor activation.

  2003cites this paper
• Tamapin, a Venom Peptide from the Indian Red Scorpion (Mesobuthus tamulus) That Targets Small Conductance Ca2+-activated K+ Channels and Afterhyperpolarization Currents in Central Neurons*

  2002cites this paper
• A locus for simple pure febrile seizures maps to chromosome 6q22-q24.

  2002cites this paper
• Tetanus toxin induces long-term changes in excitation and inhibition in the rat hippocampal CA1 area.

  2002cites this paper
• Mechanisms controlling bursting activity induced by disinhibition in spinal cord networks

  2002cites this paper
• Design and Characterization of a Highly Selective Peptide Inhibitor of the Small Conductance Calcium-activated K+Channel, SkCa2*

  2001cites this paper
• Synaptic regulation of the slow Ca2+-activated K+ current in hippocampal CA1 pyramidal neurons: implication in epileptogenesis.

  2001cites this paper
• ScholarWorks @ UTRGV ScholarWorks @ UTRGV

  year unknowncites this paper
• Neurobiology of Disease Mitochondrial Calcium Ion and Membrane Potential Transients Follow the Pattern of Epileptiform Discharges in Hippocampal Slice Cultures Emerging Evidence Suggests That Mitochondrial Dysfunction Contributes to the Pathophysiology of Epilepsy. Recurrent Mitochondrial Ca 2ϩ Ion

  year unknowncites this paper