Biochemical characterization of mouse microsomal prostaglandin E synthase-1 and its colocalization with cyclooxygenase-2 in peritoneal macrophages.

No abstract is available for this paper.

• Publication year

  2002

• Venue

  Archives of Biochemistry and Biophysics

• Publication date

  2002-01-15

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1006/ABBI.2001.2614PMID 11795891
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Microsomal Prostaglandin E Synthase Is Regulated by Proinflammatory Cytokines and Glucocorticoids in Primary Rheumatoid Synovial Cells1

  2001cited by this paper
• Inflammatory response: Pathway across the blood–brain barrier

  2001cited by this paper
• Coexpression of Microsomal-Type Prostaglandin E Synthase with Cyclooxygenase-2 in Brain Endothelial Cells of Rats during Endotoxin-Induced Fever

  2001cited by this paper
• Regulation of Prostaglandin E2 Biosynthesis by Inducible Membrane-associated Prostaglandin E2 Synthase That Acts in Concert with Cyclooxygenase-2*

  2000cited by this paper
• Human glutathione dependent prostaglandin E synthase: gene structure and regulation

  2000cited by this paper
• Coordinate up- and down-regulation of glutathione-dependent prostaglandin E synthase and cyclooxygenase-2 in A549 cells. Inhibition by NS-398 and leukotriene C4.

  2000cited by this paper
• Molecular Identification of Cytosolic Prostaglandin E2 Synthase That Is Functionally Coupled with Cyclooxygenase-1 in Immediate Prostaglandin E2Biosynthesis*

  2000cited by this paper
• Identification of Mu-Class Glutathione Transferases M2-2 and M3-3 as Cytosolic Prostaglandin E Synthases in the Human Brain

  2000cited by this paper
• Identification of human prostaglandin E synthase: a microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target.

  1999cited by this paper
• Arachidonic Acid Is Preferentially Metabolized by Cyclooxygenase-2 to Prostacyclin and Prostaglandin E2 *

  1999cited by this paper
• Purification and characterization of membrane-bound prostaglandin E synthase from bovine heart.

  1999cited by this paper
• Cyclooxygenase-2: molecular biology, pharmacology, and neurobiology.

  1999cited by this paper
• Prostaglandin E2 in the Pathogenesis of Fever: An Update a

  1998cited by this paper
• Elevated interleukin 6 is induced by prostaglandin E2 in a murine model of inflammation: possible role of cyclooxygenase-2.

  1996cited by this paper
• Selective neutralization of prostaglandin E2 blocks inflammation, hyperalgesia, and interleukin 6 production in vivo

  1996cited by this paper
• Prostaglandin endoperoxide H synthases-1 and -2.

  1996cited by this paper
• Allodynia evoked by intrathecal administration of prostaglandin E2 to conscious mice

  1994cited by this paper
• Allodynia evoked by intrathecal administration of prostaglandin F2&agr; to conscious mice

  1992cited by this paper
• Molecular mechanisms of sleep‐wake regulation: roles of prostaglandins D2 and E2

  1991cited by this paper
• Biochemical and immunological demonstration of prostaglandin D2, E2, and F2 alpha formation from prostaglandin H2 by various rat glutathione S-transferase isozymes.

  1988cited by this paper
• II. Isozyme specificity of rat liver glutathione S-transferases in the formation of PGF2α and PGE2 from PGH2☆

  1987cited by this paper
• Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction.

  1987cited by this paper
• Biochemical and immunological characterization of rat spleen prostaglandin D synthetase.

  1987cited by this paper
• Purification and Properties of Prostaglandin H‐E Isomerase from the Cytosol of Human Brain: Identification as Anionic Forms of Glutathione S‐Transferase

  1987cited by this paper
• Isozyme specificity of rat liver glutathione S-transferases in the formation of PGF2 alpha and PGE2 from PGH2.

  1987cited by this paper
• Purification of PGH-PGE isomerase from sheep vesicular glands.

  1982cited by this paper
• Purification and properties of prostaglandin D synthetase from rat brain.

  1979cited by this paper
• Prostaglandin endoperoxide E isomerase from bovine vesicular gland microsomes, a glutathione-requiring enzyme.

  1977cited by this paper
• Prostaglandin synthetase system--resolution into oxygenase and isomerase components.

  1974cited by this paper

• Inhibition of DYRK1B BY C81 impedes inflammatory processes in leukocytes by reducing STAT3 activity

  2025cites this paper
• Cooperation between Prostaglandin E2 and Epidermal Growth Factor Receptor in Cancer Progression: A Dual Target for Cancer Therapy

  2023cites this paper
• Iristectorigenin C suppresses LPS-induced macrophages activation by regulating mPGES-1 expression and p38/JNK pathway.

  2023cites this paper
• Microsomal prostaglandin E2 synthase-1 and its inhibitors: molecular mechanisms and therapeutic significance.

  2021cites this paper
• Dietary oleuropein and its new acyl-derivate attenuate murine lupus nephritis through HO-1/Nrf2 activation and suppressing JAK/STAT, NF-κB, MAPK and NLRP3 inflammasome signaling pathways.

  2019cites this paper
• Triterpenoid Saponins from Anemone flaccida Suppress Tumor Cell Proliferation by Regulating MAPK, PD1/PDL1, and STAT3 Signaling Pathways and Altering Cancer Metabolism

  2019cites this paper
• OTT_A_212666 10917..10930

  2019cites this paper
• Physiological and pathophysiological implications of PGE2 and the PGE2 synthases in the kidney.

  2018cites this paper
• Prostaglandin E Pathway in Uterine Tissue During Window of Preimplantation in Female Mice Mated With Intact and Seminal Vesicle–Excised Male

  2018cites this paper
• Polyphenolic extract from extra virgin olive oil inhibits the inflammatory response in IL-1β-activated synovial fibroblasts

  2018cites this paper
• A Cybernetic Approach to Modeling Lipid Metabolism in Mammalian Cells

  2018cites this paper
• Extra-virgin olive oil phenols hydroxytyrosol and hydroxytyrosol acetate, down-regulate the production of mediators involved in joint erosion in human synovial cells

  2017cites this paper
• Prostaglandin synthases: Molecular characterization and involvement in prostaglandin biosynthesis.

  2017cites this paper
• Impact of Cyclooxygenase-2 1195 G-Carrier Genotype Associated with Intestinal Metaplasia and Endoscopic Findings Based on Kyoto Classification

  2017cites this paper
• Sesame Oil and Rice Bran Oil Ameliorates Adjuvant-Induced Arthritis in Rats: Distinguishing the Role of Minor Components and Fatty Acids

  2016cites this paper
• Computational Modeling of Competitive Metabolism between ω3- and ω6-Polyunsaturated Fatty Acids in Inflammatory Macrophages.

  2016cites this paper
• Dietary extra virgin olive oil attenuates kidney injury in pristane-induced SLE model via activation of HO-1/Nrf-2 antioxidant pathway and suppression of JAK/STAT, NF-κB and MAPK activation.

  2016cites this paper
• Apigenin supplementation protects the development of dextran sulfate sodium-induced murine experimental colitis by inhibiting canonical and non-canonical inflammasome signaling pathways.

  2016cites this paper
• Preventive effects of dietary hydroxytyrosol acetate, an extra virgin olive oil polyphenol in murine collagen-induced arthritis.

  2015cites this paper
• Inhibition of P2Y6 receptor-mediated phospholipase C activation and Ca(2+) signalling by prostaglandin E2 in J774 murine macrophages.

  2015cites this paper
• Molecular and cellular pharmacology Inhibition of P 2 Y 6 receptor-mediated phospholipase C activation and Ca 2 þ signalling by prostaglandin E 2 in J 774 murine macrophages

  2015cites this paper
• Melatonin modulates microsomal PGE synthase 1 and NF‐E2‐related factor‐2‐regulated antioxidant enzyme expression in LPS‐induced murine peritoneal macrophages

  2014influential citation
• InjuryOntogeny and Functions in Acute Liver and Resident Kupffer Cells Display Different Infiltrating Monocyte-Derived Macrophages

  2014cites this paper
• Modeling of eicosanoid fluxes reveals functional coupling between cyclooxygenases and terminal synthases.

  2014cites this paper
• Persisting eicosanoid pathways in rheumatic diseases

  2014cites this paper
• Anti-inflammatory and joint protective effects of extra-virgin olive-oil polyphenol extract in experimental arthritis.

  2014cites this paper
• Melatonin modulates microsomal PGE synthase 1 and NF-E2-related

  2014cites this paper
• Infiltrating Monocyte-Derived Macrophages and Resident Kupffer Cells Display Different Ontogeny and Functions in Acute Liver Injury

  2014cites this paper
• Mechanisms of anti-inflammatory property of Anacardium occidentale stem bark: inhibition of NF-κB and MAPK signalling in the microglia.

  2013cites this paper
• Review: Systemic inflammation and Alzheimer's disease

  2013cites this paper
• New insights into the catalytic mechanism of Bombyx mori prostaglandin E synthase gained from structure-function analysis.

  2013cites this paper
• Crystal structure of a Bombyx mori sigma-class glutathione transferase exhibiting prostaglandin E synthase activity.

  2013cites this paper
• Observation of two modes of inhibition of human microsomal prostaglandin E synthase 1 by the cyclopentenone 15-deoxy-Δ(12,14)-prostaglandin J(2).

  2012cites this paper
• FcεRI, but not FcγR, signals induce prostaglandin D2 and E2 production from basophils.

  2011cites this paper
• Enzymes of the cyclooxygenase pathways of prostanoid biosynthesis.

  2011cites this paper
• The 5‐lipoxygenase inhibitor, zileuton, suppresses prostaglandin biosynthesis by inhibition of arachidonic acid release in macrophages

  2010cites this paper
• Microsomal Prostaglandin E Synthase-1 in Rheumatic Diseases

  2010cites this paper
• mPGES-1 as a target for cancer suppression: A comprehensive invited review "Phospholipase A2 and lipid mediators".

  2010cites this paper
• Biochemical, Functional, and Pharmacological Characterization of AT-56, an Orally Active and Selective Inhibitor of Lipocalin-type Prostaglandin D Synthase

  2009cites this paper
• Expression of Microsomal Prostaglandin E Synthase-1 in Fibroblasts of Rabbit Alkali-Burned Corneas

  2008cites this paper
• Physiological regulation of prostaglandins in the kidney.

  2008cites this paper
• Hematopoietic Prostaglandin D Synthase and DP1 Receptor Are Selectively Upregulated in Microglia and Astrocytes Within Senile Plaques From Human Patients and in a Mouse Model of Alzheimer Disease

  2007influential citation
• Physiologic and pathophysiologic roles of lipid mediators in the kidney.

  2007cites this paper
• Endothelin A receptor blockade reduces diabetic renal injury via an anti-inflammatory mechanism.

  2007cites this paper
• Roles of lipid mediators in kidney injury.

  2007cites this paper
• Membrane Prostaglandin E Synthase-1: A Novel Therapeutic Target

  2007influential citation
• CHAPTER 15 – The Differential Role of Prostaglandin E2 Receptors in the CNS Response to Systemic Immune Challenge

  2007cites this paper
• Studies on molecular properties and functional regulation of terminal leukotriene C4 synthases and cysteinyl-leukotriene receptor signalling in human endothelium

  2007influential citation
• involvement of nitric oxide and cytokines in mediator pathways under inflammatory conditions

  2007cites this paper
• (Aza)indolderivate, substituiert in Position 5, ihre pharmazeutische Zusammensetzungen, Intermediate und Methoden zur Herstellung

  2007cites this paper
• Regulation of the microsomal prostaglandin E synthase‐1 in polarized mononuclear phagocytes and its constitutive expression in neutrophils

  2007cites this paper
• Activation of synoviocytes by the secreted phospholipase A2 motif in the VP1-unique region of parvovirus B19 minor capsid protein.

  2006cites this paper
• Presence and Characterization of Prostaglandin D2–Related Molecules in Nasal Mucosa of Patients with Allergic Rhinitis

  2006cites this paper
• The differential role of prostaglandin E2 receptors EP3 and EP4 in regulation of fever.

  2006cites this paper
• Differentiation‐dependent regulation of the cyclooxygenase cascade during adipogenesis suggests a complex role for prostaglandins

  2006cites this paper
• Structural and Functional Characterization of HQL-79, an Orally Selective Inhibitor of Human Hematopoietic Prostaglandin D Synthase*

  2006cites this paper
• mPGES-1: a key regulator of fever and neonatal respiratory depression

  2006influential citation
• Role of prostaglandin D2 and E2 terminal synthases in chronic rhinosinusitis

  2006cites this paper
• Prostaglandin E synthase in the pathophysiology of arthritis

  2005cites this paper
• Redirection of Eicosanoid Metabolism in mPGES-1-deficient Macrophages*

  2005cites this paper
• Microsomal prostaglandin E synthase (mPGES)-1, mPGES-2 and cytosolic PGES expression in human gastritis and gastric ulcer tissue

  2005cites this paper
• Innate immune reaction in response to seizures: implications for the neuropathology associated with epilepsy.

  2004cites this paper
• Deletion of Microsomal Prostaglandin E2 (PGE2) Synthase-1 Reduces Inducible and Basal PGE2 Production and Alters the Gastric Prostanoid Profile*

  2004cites this paper
• Hyperplastic gastric tumors induced by activated macrophages in COX‐2/mPGES‐1 transgenic mice

  2004cites this paper
• Intraparenchymal administration of interleukin-1beta induces cyclooxygenase-2-mediated expression of membrane- and cytosolic-associated prostaglandin E synthases in mouse brain.

  2004cites this paper
• Species-specific expression of microsomal prostaglandin E synthase-1 and cyclooxygenases in male monkey reproductive organs.

  2004cites this paper
• Differential localization of prostaglandin E synthase isoforms in human placental cell types.

  2004cites this paper
• Antithrombin reduces ischemia/reperfusion-induced liver injury in rats by activation of cyclooxygenase-1

  2004cites this paper
• Success of prostaglandin E2 in structure–function is a challenge for structure-based therapeutics

  2003cites this paper
• Characterization of human glutathione-dependent microsomal prostaglandin E synthase-1

  2003cites this paper
• Impaired adrenocorticotropic hormone response to bacterial endotoxin in mice deficient in prostaglandin E receptor EP1 and EP3 subtypes

  2003cites this paper
• Cooperation of cyclooxygenase 1 and cyclooxygenase 2 in intestinal polyposis.

  2003cites this paper
• Arthritis Model Production in the Rat Adjuvant-Induced 2 E Cyclooxygenase-2-Dependent Prostaglandin Up-Regulated During Major Terminal Synthase That Is Selectively Microsomal Prostaglandin E Synthase-1 Is a and

  2003cites this paper
• Characterization of human glutathione-dependent microsomal prostaglandin E synthase-1

  2003cites this paper
• Paracetamol effectively reduces prostaglandin E2 synthesis in brain macrophages by inhibiting enzymatic activity of cyclooxygenase but not phospholipase and prostaglandin E synthase

  2003cites this paper
• Impaired inflammatory and pain responses in mice lacking an inducible prostaglandin E synthase

  2003cites this paper
• Inhibition of IL-1β-dependent prostaglandin E2 release by antisense microsomal prostaglandin E synthase 1 oligonucleotides in A549 cells

  2003cites this paper
• Microsomal Prostaglandin E Synthase-1 Is a Major Terminal Synthase That Is Selectively Up-Regulated During Cyclooxygenase-2-Dependent Prostaglandin E2 Production in the Rat Adjuvant-Induced Arthritis Model

  2003cites this paper
• Human Microsomal Prostaglandin E Synthase-1

  2003cites this paper
• Immunohistochemical localization of microsomal PGE synthase-1 and cyclooxygenases in male mouse reproductive organs.

  2002cites this paper
• Purification and characterization of recombinant microsomal prostaglandin E synthase-1.

  2002cites this paper
• Prostaglandin E2 and cAMP promote B lymphocyte class switching to IgG1.

  2002cites this paper
• A Key Role for Old Yellow Enzyme in the Metabolism of Drugs by Trypanosoma cruzi

  2002cites this paper