Genome-wide genotyping of acute myeloid leukemia with translocation t(9;11)(p22;q23) reveals novel recurrent genomic alterations

M. Kühn,L. Bullinger,S. Gröschel,J. Krönke,J. Edelmann,F. Rücker,Karina Eiwen,P. Paschka,V. Gaidzik,K. Holzmann,R. Schlenk,H. Döhner,K. Döhner

Published 2014 in Haematologica

ABSTRACT

Chromosomal translocations of the mixed-lineage leukemia (MLL) gene are common genetic events in acute leukemias. In acute myeloid leukemia (AML), the translocation t(9;11)(p22;q23) [subsequently referred to as t(9;11)], resulting in the MLL-MLLT3-fusion protein, is the most common translocation

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