The Influence of Fruit and Vegetable Consumption and Genetic Variation on NAD(P)H:Quinone Oxidoreductase (NQO1) Phenotype in an Endoscopy-Based Population

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Nutrition and Cancer

• Publication date

  2008-03-17

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1080/01635580701684849PMID 18444152
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Glutathione S-transferase phenotypes in relation to genetic variation and fruit and vegetable consumption in an endoscopy-based population.

  2006cited by this paper
• NAD(P)H:Quinone Oxidoreductase 1 (NQO1) Pro187Ser Polymorphism and the Risk of Lung, Bladder, and Colorectal Cancers: a Meta-analysis

  2006cited by this paper
• Role of epoxide hydrolase, NAD(P)H:quinone oxidoreductase, cytochrome P450 2E1 or alcohol dehydrogenase genotypes in susceptibility to colorectal cancer.

  2006cited by this paper
• Structural basis for defects of Keap1 activity provoked by its point mutations in lung cancer.

  2006cited by this paper
• CYP1A1 Val462 and NQO1 Ser187 polymorphisms, cigarette use, and risk for colorectal adenoma.

  2005cited by this paper
• Modulation of xenobiotic metabolising enzymes by anticarcinogens -- focus on glutathione S-transferases and their role as targets of dietary chemoprevention in colorectal carcinogenesis.

  2005cited by this paper
• Proportion of colon cancer risk that might be preventable in a cohort of middle-aged US men

  2004cited by this paper
• Contribution of NAD(P)H:quinone oxidoreductase 1 to protection against carcinogenesis, and regulation of its gene by the Nrf2 basic-region leucine zipper and the arylhydrocarbon receptor basic helix-loop-helix transcription factors.

  2004cited by this paper
• NAD(P)H:quinone oxidoreductase 1 (NQO1, DT-diaphorase), functions and pharmacogenetics.

  2004cited by this paper
• NAD(P)H:Quinone oxidoreductase-1 C609T polymorphism analysis in human superficial bladder cancers: relationship of genotype status to NQO1 phenotype and clinical response to Mitomycin C.

  2004cited by this paper
• Quinone Reductases Multitasking in the Metabolic World

  2004cited by this paper
• Induction of detoxifying enzymes by garlic organosulfur compounds through transcription factor Nrf2: effect of chemical structure and stress signals.

  2004cited by this paper
• Chemoprevention through the Keap1-Nrf2 signaling pathway by phase 2 enzyme inducers.

  2004cited by this paper
• Botanicals in Cancer Chemoprevention

  2004cited by this paper
• Identification of polymorphisms in the promoter region of the human NRF2 gene.

  2004cited by this paper
• Association between NAD(P)H: Quinone oxidoreductase 1 (NQ01) inactivating C609T polymorphism and adenocarcinoma of the upper gastrointestinal tract

  2003cited by this paper
• Evaluation of NQO1 gene expression and variant allele in human NSCLC tumors and matched normal lung tissue.

  2002cited by this paper
• Lack of NQO1 induction in human tumor cells is not due to changes in the promoter region of the gene.

  2002cited by this paper
• A physiological threshold for protection against menadione toxicity by human NAD(P)H:quinone oxidoreductase (NQO1) in Chinese hamster ovary (CHO) cells.

  2002cited by this paper
• Implication of alternative splicing for expression of a variant NAD(P)H:quinone oxidoreductase-1 with a single nucleotide polymorphism at 465C>T.

  2002cited by this paper
• NAD(P)H:quinone oxidoreductase (NQO1) polymorphism, exposure to benzene, and predisposition to disease: A HuGE review

  2002cited by this paper
• Molecular Cloning: A Laboratory Manual

  2001cited by this paper
• Nomenclature for the description of human sequence variations

  2001cited by this paper
• Rapid polyubiquitination and proteasomal degradation of a mutant form of NAD(P)H:quinone oxidoreductase 1.

  2001cited by this paper
• A European carotenoid database to assess carotenoid intakes and its use in a five-country comparative study

  2001influential reference
• Dietary indoles and isothiocyanates that are generated from cruciferous vegetables can both stimulate apoptosis and confer protection against DNA damage in human colon cell lines.

  2001cited by this paper
• Factors influencing the induction of DT-diaphorase activity by 1,2-dithiole-3-thione in human tumor cell lines.

  2001cited by this paper
• Chronic dosing of oltipraz in people at increased risk for colorectal cancer.

  2001cited by this paper
• NAD(P)H:quinone oxidoreductase 1 (NQO1): chemoprotection, bioactivation, gene regulation and genetic polymorphisms.

  2000influential reference
• Modulation of human glutathione S-transferases by botanically defined vegetable diets.

  2000cited by this paper
• Regulation of genes encoding NAD(P)H:quinone oxidoreductases.

  2000cited by this paper
• Assessment of the relationship between genotypic status of a DT-diaphorase point mutation and enzymatic activity

  2000cited by this paper
• Immunodetection of NAD(P)H:quinone oxidoreductase 1 (NQO1) in human tissues.

  2000cited by this paper
• Genotype-phenotype relationships in studies of a polymorphism in NAD(P)H:quinone oxidoreductase 1.

  1999cited by this paper
• NAD(P)H:quinone oxidoreductase: polymorphisms and allele frequencies in Caucasian, Chinese and Canadian Native Indian and Inuit populations.

  1998cited by this paper
• Macrophage activation by polycyclic aromatic hydrocarbons: evidence for the involvement of stress-activated protein kinases, activator protein-1, and antioxidant response elements.

  1998cited by this paper
• Involvement of activator protein-1 and nuclear factor-kappaB transcription factors in the control of the DT-diaphorase expression induced by mitomycin C treatment.

  1997influential reference
• Alternative splicing and differential expression of DT-diaphorase transcripts in human colon tumors and in peripheral mononuclear cells in response to mitomycin C treatment.

  1996cited by this paper
• Modulation of gene expression in subjects at risk for colorectal cancer by the chemopreventive dithiolethione oltipraz.

  1996cited by this paper
• Effects of consumption of Brussels sprouts on intestinal and lymphocytic glutathione S-transferases in humans.

  1995cited by this paper
• Identification of a class 3 aldehyde dehydrogenase in human saliva and increased levels of this enzyme, glutathione S-transferases, and DT-diaphorase in the saliva of subjects who continually ingest large quantities of coffee or broccoli.

  1995cited by this paper
• An alternatively spliced form of NQO1 (DT-diaphorase) messenger RNA lacking the putative quinone substrate binding site is present in human normal and tumor tissues.

  1995cited by this paper
• Consumption of Brussels sprouts results in elevated alpha-class glutathione S-transferase levels in human blood plasma.

  1994cited by this paper
• The human glutathione S-transferase P1-1 gene: modulation of expression by retinoic acid and insulin.

  1993cited by this paper
• Quinone chemistry and toxicity.

  1992cited by this paper
• NAD(P)H:quinone oxidoreductase gene expression in human colon carcinoma cells: characterization of a mutation which modulates DT-diaphorase activity and mitomycin sensitivity.

  1992cited by this paper
• Induction of NAD(P)H:quinone reductase in human peripheral blood lymphocytes.

  1991cited by this paper
• Human NAD(P)H:quinone oxidoreductase (NQO1) gene structure and induction by dioxin.

  1991cited by this paper
• Increase of NAD(P)H:quinone reductase by dietary antioxidants: possible role in protection against carcinogenesis and toxicity.

  1980cited by this paper
• TOXICOKINETICS AND METABOLISM

  year unknowncited by this paper

• Association of NQO1 levels and its genetic polymorphism with susceptibility to methamphetamine dependence

  2021cites this paper
• A Functional NQO1 609C>T Polymorphism and Risk of Gastrointestinal Cancers: A Meta-Analysis

  2012cites this paper
• Association of NQO1 rs1800566 polymorphism and the risk of colorectal cancer: a meta-analysis

  2012cites this paper
• Fruits and vegetables, detoxification genes and intermediate endpoints in colorectal cancer prevention

  2008cites this paper