Opening of the mitoKATP channel and decoupling of mitochondrial complex II and III contribute to the suppression of myocardial reperfusion hyperoxygenation

No abstract is available for this paper.

• Publication year

  2010

• Venue

  Molecular and Cellular Biochemistry

• Publication date

  2010-04-01

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1007/s11010-009-0283-2PMID 19851835PMCID PMC3738814
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2007influential reference
• Measurement of reactive oxygen species in cardiovascular studies.

  2007influential reference
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  2007influential reference
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  1999influential reference
• Modulation of mitochondrial ATP-dependent K+ channels by protein kinase C.

  1998cited by this paper
• Myocardial oxygen tension in isolated erythrocyte-perfused rat hearts and comparison with crystalloid media.

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  1991influential reference
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  1989cited by this paper
• Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium.

  1986cited by this paper
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  1980cited by this paper
• Mitochondrial production of superoxide anions and its relationship to the antimycin insensitive respiration

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  1969cited by this paper
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• Protein measurement with the Folin phenol reagent.

  1951cited by this paper

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