Expression Pattern and Role of a 60-Kilodalton Progesterone Binding Protein in Regulating Granulosa Cell Apoptosis: Involvement of the Mitogen-Activated Protein Kinase Cascade1

No abstract is available for this paper.

• Publication year

  2003

• Venue

  Biology of Reproduction

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1095/biolreprod.102.007542PMID 12493703
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• Molecular mechanisms mediating mammalian mitogen-activated protein kinase (MAPK) kinase (MEK)-MAPK cell survival signals.

  2001cited by this paper
• Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions.

  2001cited by this paper
• Taxol-induced apoptosis depends on MAP kinase pathways (ERK and p38) and is independent of p53

  2001influential reference
• Raf-MEK-Erk Cascade in Anoikis Is Controlled by Rac1 and Cdc42 via Akt

  2001cited by this paper
• E-Cadherin-Mediated Cell Contact Prevents Apoptosis of Spontaneously Immortalized Granulosa Cells by Regulating Akt Kinase Activity1

  2001cited by this paper
• Characterization of a Putative Membrane Receptor for Progesterone in Rat Granulosa Cells1

  2001cited by this paper
• Progesterone Is an Autocrine/Paracrine Regulator of Human Granulosa Cell Survival in Vitro

  2000cited by this paper
• Hormonal regulation of early follicle development in the rat ovary.

  2000cited by this paper
• Progesterone Receptor-Mediated Inhibition of Apoptosis in Granulosa Cells Isolated from Rats Treated with Human Chorionic Gonadotropin1

  2000cited by this paper
• Basic fibroblast growth factor inhibits apoptosis of spontaneously immortalized granulosa cells by regulating intracellular free calcium levels through a protein kinase Cdelta-dependent pathway.

  2000cited by this paper
• Ovulation: a multi-gene, multi-step process.

  2000cited by this paper
• Time-Dependent Ovulation Inhibition of a Selective Progesterone-Receptor Antagonist (Org 31710) and Effects on Ovulatory Mediators in the In Vitro Perfused Rat Ovary1

  2000cited by this paper
• Basic Fibroblast Growth Factor Inhibits Apoptosis of Spontaneously Immortalized Granulosa Cells by Regulating Intracellular Free Calcium Levels through a Protein Kinase Cδ-Dependent Pathway* * This work was supported by NIH Grant HD-33467.

  2000cited by this paper
• Molecular Events Defining Follicular Developments and Steroidogenesis in the Ovary

  2000cited by this paper
• Expression of 11beta-hydroxysteroid dehydrogenase, glucocorticoid receptor, and mineralocorticoid receptor genes in rat ovary.

  1999cited by this paper
• Progesterone maintains large rat granulosa cell viability indirectly by stimulating small granulosa cells to synthesize basic fibroblast growth factor.

  1999cited by this paper
• Apoptosis of ovarian granulosa cells: Correlation with the reduced activity of ERK‐signaling module

  1999cited by this paper
• Induction of apoptosis in luteinized granulosa cells by the MAP kinase kinase (MEK) inhibitor PD98059.

  1999cited by this paper
• Expression of 11β-Hydroxysteroid Dehydrogenase, Glucocorticoid Receptor, and Mineralocorticoid Receptor Genes in Rat Ovary

  1999cited by this paper
• Progesterone mediates its anti-mitogenic and anti-apoptotic actions in rat granulosa cells through a progesterone-binding protein with gamma aminobutyric acidA receptor-like features.

  1998cited by this paper
• Follicular growth and ovarian dynamics in mammals.

  1997cited by this paper
• Placing progesterone in the apoptotic pathway.

  1997cited by this paper
• Mifepristone and ovarian function.

  1996cited by this paper
• Effect of in vivo gonadotropin treatment on the ability of progesterone, estrogen, and cyclic adenosine 5'-monophosphate to inhibit insulin-dependent granulosa cell mitosis in vitro.

  1995cited by this paper
• Proliferative and steroidogenic capabilities of rat granulosa cells of different sizes.

  1995cited by this paper
• Identification of a deoxyribonuclease I-like endonuclease in rat granulosa and luteal cell nuclei.

  1995cited by this paper
• The cell surface progesterone receptor which stimulates calcium influx in human sperm is unlike the A ring reduced steroid site on the GABAA receptor/chloride channel.

  1994cited by this paper
• Functional and ultrastructural characteristics of two types of rat granulosa cell cultured in the presence of FSH or transforming growth factor alpha (TGF-alpha).

  1993cited by this paper
• Hormonal regulation, localization, and functional activity of the progesterone receptor in granulosa cells of rat preovulatory follicles.

  1993cited by this paper
• Concomitant alterations of desmosomes, adhesiveness, and diffusion through gap junction channels in a rat ovarian transformation model system.

  1993cited by this paper
• Functional and ultrastructural characteristics of two types of rat granulosa cell cultured in the presence of FSH or transforming growth factor α (TGF-α)

  1993cited by this paper
• GABAA receptors: ligand-gated Cl- ion channels modulated by multiple drug-binding sites.

  1992cited by this paper
• Transient expression of progesterone receptor messenger RNA in ovarian granulosa cells after the preovulatory luteinizing hormone surge.

  1991cited by this paper
• Development of follicles in the mammalian ovary.

  1991cited by this paper
• Heterogeneity in granulosa cells of developing rat follicles

  1991cited by this paper
• In vitro steroidogenesis by primary to antral follicles in the hamster during the periovulatory period: effects of follicle-stimulating hormone, luteinizing hormone, and prolactin.

  1987cited by this paper
• Changes in inhibin activity, and progesterone, oestrogen and androstenedione concentrations, in rat follicular fluid throughout the oestrous cycle.

  1983cited by this paper
• Rat ovary glucocorticoid receptor: identification and characterization.

  1982cited by this paper
• Characterization of cytoplasmic progesterone receptors in rat granulosa cells. Evidence for nuclear translocation.

  1981cited by this paper
• Progestins inhibit FSH-stimulated granulosa estrogen production at a post-cAMP site.

  1981cited by this paper
• Progestins inhibit FSH-stimulated steroidogenesis in cultured rat granulosa cells.

  1980cited by this paper
• Progesterone receptor in the rat ovary: further characterization and localization in the granulosa cell.

  1979cited by this paper
• Progesterone "receptor" in rat ovary.

  1979cited by this paper

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  2025cites this paper
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  2025cites this paper
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  2022cites this paper
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  2016cites this paper
• Non-canonical progesterone signaling in granulosa cell function.

  2014influential citation
• Progesterone regulation of progesterone receptor membrane component 1 (PGRMC1) sumoylation and transcriptional activity in spontaneously immortalized granulosa cells.

  2012cites this paper
• A Novel Role for Progesterone and Progesterone Receptor Membrane Component 1 in Regulating Spindle Microtubule Stability During Rat and Human Ovarian Cell Mitosis1

  2011cites this paper
• rogesterone inhibits apoptosis in part by PGRMC 1-regulated gene expression

  2010cites this paper
• Progesterone inhibits apoptosis in part by PGRMC1-regulated gene expression.

  2010cites this paper
• Progesterone receptor membrane component-1 regulates the development and Cisplatin sensitivity of human ovarian tumors in athymic nude mice.

  2009cites this paper
• Board-invited review: Estrogen and progesterone signaling: genomic and nongenomic actions in domestic ruminants.

  2008cites this paper
• Systematic expression analysis and antibody screening do not support the existence of naturally occurring progesterone receptor (PR)-C, PR-M, or other truncated PR isoforms.

  2008cites this paper
• Neurosteroids are excitatory in supraoptic neurons but inhibitory in the peripheral nervous system: it is all about oxytocin and progesterone receptors.

  2008cites this paper
• Zyklusabhängige Expression und Lokalisation der Isoform C des Progesteronrezeptors im humanen Endometrium im Vergleich mit den Isoformen B und A

  2008cites this paper
• Progesterone maintains basal intracellular adenosine triphosphate levels and viability of spontaneously immortalized granulosa cells by promoting an interaction between 14-3-3sigma and ATP synthase beta/precursor through a protein kinase G-dependent mechanism.

  2007cites this paper
• The regulation of kit ligand expression in rat granulosa cells by ovarian factors

  2007cites this paper
• Non-genomic actions of progesterone in the normal and neoplastic mammalian ovary.

  2007cites this paper
• CHAPTER 15 – Steroid Receptors in the Ovary and Uterus

  2006cites this paper
• Rapid inhibition of Ca2+ influx by neurosteroids in murine embryonic sensory neurones.

  2006cites this paper
• Expression and localization of the progesterone receptor in mouse and human reproductive organs.

  2006cites this paper
• Regulation of signal transduction pathways by estrogen and progesterone.

  2005cites this paper
• Progesterone Regulates Granulosa Cell Viability Through a Protein Kinase G-Dependent Mechanism That May Involve 14-3-3σ1

  2004cites this paper
• Haem oxygenase augments porcine granulosa cell apoptosis in vitro.

  2004cites this paper
• Expression of progesterone receptors A and B in the mouse ovary during the estrous cycle.

  2004cites this paper
• Nongenomic Inhibition of Oxytocin Binding by Progesterone in the Ovine Uterus1

  2004cites this paper
• Involvement of an unnamed protein, RDA288, in the mechanism through which progesterone mediates its antiapoptotic action in spontaneously immortalized granulosa cells.

  2004cites this paper
• Rapid actions of progesterone on granulosa cells.

  2004cites this paper
• Progesterone as a regulator of granulosa cell viability.

  2003cites this paper