PDEF and PDEF-induced proteins as candidate tumor antigens for T cell and antibody-mediated immunotherapy of breast cancer

No abstract is available for this paper.

• Publication year

  2010

• Venue

  Immunologic research

• Publication date

  2010-03-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1007/s12026-009-8129-2PMID 19763888
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• MUC1-induced transcriptional programs associated with tumorigenesis predict outcome in breast and lung cancer.

  2009cited by this paper
• Sam-Pointed Domain Containing Ets Transcription Factor in Luminal Breast Cancer Pathogenesis

  2009influential reference
• Assessment of immunologic response and recurrence patterns among patients with clinical recurrence after vaccination with a preventive HER2/neu peptide vaccine: from US Military Cancer Institute Clinical Trials Group Study I-01 and I-02

  2008cited by this paper
• Therapeutic anti-VEGF antibodies.

  2008cited by this paper
• The E75 HER2/neu peptide vaccine

  2008cited by this paper
• Carcinoembryonic Antigen Cell Adhesion Molecule 6 Predicts Breast Cancer Recurrence following Adjuvant Tamoxifen

  2008cited by this paper
• Plasmacytoid dendritic cells from mouse tumor-draining lymph nodes directly activate mature Tregs via indoleamine 2,3-dioxygenase.

  2007cited by this paper
• Expression characteristics of prostate-derived Ets factor support a role in breast and prostate cancer progression.

  2007cited by this paper
• Rituximab and its role as maintenance therapy in non-Hodgkin lymphoma

  2007cited by this paper
• Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer

  2007cited by this paper
• Natural Regulatory T Cells and De Novo-Induced Regulatory T Cells Contribute Independently to Tumor-Specific Tolerance1

  2007cited by this paper
• Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and its therapeutic potential in breast and gynecologic cancers.

  2007cited by this paper
• ETS‐family genes in pancreatic development

  2007cited by this paper
• Expression patterns of CEACAM5 and CEACAM6 in primary and metastatic cancers

  2007cited by this paper
• Anti-idiotype antibody response after vaccination correlates with better overall survival in follicular lymphoma.

  2007cited by this paper
• The Universal Character of the Tumor-Associated Antigen Survivin

  2007cited by this paper
• ETS transcription factors in endocrine systems.

  2007cited by this paper
• Regulation of vascular inflammation and remodeling by ETS factors.

  2006cited by this paper
• Epidermal growth factor receptor targeting in cancer.

  2006cited by this paper
• Comparative analysis of regulatory and effector T cells in progressively growing versus rejecting tumors of similar origins.

  2006cited by this paper
• Tumor cell expression of HLA-DM associates with a Th1 profile and predicts improved survival in breast carcinoma patients.

  2006cited by this paper
• Gr-1+CD115+ immature myeloid suppressor cells mediate the development of tumor-induced T regulatory cells and T-cell anergy in tumor-bearing host.

  2006cited by this paper
• Immune suppression in the tumor microenvironment.

  2006cited by this paper
• Transgenic mice with mammary gland targeted expression of human cortactin do not develop (pre-malignant) breast tumors: studies in MMTV-cortactin and MMTV-cortactin/-cyclin D1 bitransgenic mice

  2006cited by this paper
• CXCR4: a key receptor in the crosstalk between tumor cells and their microenvironment.

  2006cited by this paper
• Type, Density, and Location of Immune Cells Within Human Colorectal Tumors Predict Clinical Outcome

  2006cited by this paper
• Tumorigenicity of interleukin-2 (IL-2)-cDNA-transfected L1210 lymphoma and its in vivo variants is modulated by changes in IL-2 expression; potential therapeutic implications

  2005cited by this paper
• Structural and functional analysis of domains mediating interaction between NKX‐3.1 and PDEF

  2005cited by this paper
• Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer.

  2005cited by this paper
• The immunomodulatory protein B7-H4 is overexpressed in breast and ovarian cancers and promotes epithelial cell transformation.

  2005cited by this paper
• A putative role for psoriasin in breast tumor progression.

  2005cited by this paper
• Intraepithelial CD8+ tumor-infiltrating lymphocytes and a high CD8+/regulatory T cell ratio are associated with favorable prognosis in ovarian cancer.

  2005cited by this paper
• B7-H4 Is Highly Expressed in Ductal and Lobular Breast Cancer

  2005cited by this paper
• Adoptive cell transfer therapy following non-myeloablative but lymphodepleting chemotherapy for the treatment of patients with refractory metastatic melanoma.

  2005cited by this paper
• Analysis of the 2.0 A crystal structure of the protein-DNA complex of the human PDEF Ets domain bound to the prostate specific antigen regulatory site.

  2005cited by this paper
• The S100A7-c-Jun activation domain binding protein 1 pathway enhances prosurvival pathways in breast cancer.

  2005cited by this paper
• Alpha-catenin is required for IGF-I-induced cellular migration but not invasion in human colonic cancer cells

  2004cited by this paper
• Expression profiles frame the promoter specificity dilemma of the ETS family of transcription factors.

  2004cited by this paper
• A retinoic acid-inducible skin-specific gene (RIS-1/psoriasin): molecular cloning and analysis of gene expression in human skinin vivo and cultured skin cellsin vitro

  2004cited by this paper
• CEACAM6 gene silencing impairs anoikis resistance and in vivo metastatic ability of pancreatic adenocarcinoma cells

  2004cited by this paper
• MHC ligands and peptide motifs: first listing

  2004cited by this paper
• Human DF3/MUC1 carcinoma-associated protein functions as an oncogene

  2003cited by this paper
• B7-H4, a molecule of the B7 family, negatively regulates T cell immunity.

  2003cited by this paper
• Intratumoral T cells, recurrence, and survival in epithelial ovarian cancer.

  2003cited by this paper
• When Ets transcription factors meet their partners.

  2002cited by this paper
• Adoptive T cell therapy using antigen-specific CD8+ T cell clones for the treatment of patients with metastatic melanoma: In vivo persistence, migration, and antitumor effect of transferred T cells

  2002cited by this paper
• The ETS-domain transcription factor family

  2001cited by this paper
• The diverse role of the ETS family of transcription factors in cancer.

  2001cited by this paper
• Identification of Cyclin B1 as a Shared Human Epithelial Tumor-Associated Antigen Recognized by T Cells

  2001cited by this paper
• Prostate epithelium-derived Ets transcription factor mRNA is overexpressed in human breast tumors and is a candidate breast tumor marker and a breast tumor antigen.

  2001cited by this paper
• Identification of a tissue-specific putative transcription factor in breast tissue by serological screening of a breast cancer library.

  2001cited by this paper
• IFNγ and lymphocytes prevent primary tumour development and shape tumour immunogenicity

  2001cited by this paper
• PDEF, a Novel Prostate Epithelium-specific Ets Transcription Factor, Interacts with the Androgen Receptor and Activates Prostate-specific Antigen Gene Expression*

  2000cited by this paper
• the Identification of Tumor-reactive T-Cell Epitopes Use of Two Predictive Algorithms of the World Wide Web for Updated

  2000cited by this paper
• Regulation of Ets function by protein–protein interactions

  2000cited by this paper
• Frequency of oestrogen and progesterone receptor positivity by immunohistochemical analysis in 7016 breast carcinomas: correlation with patient age, assay sensitivity, threshold value, and mammographic screening

  2000cited by this paper
• Ets transcription factors and human disease.

  1998cited by this paper
• Ets transcription factors: nuclear effectors of the Ras-MAP-kinase signaling pathway.

  1998cited by this paper
• Oestrogen receptors and breast cancer

  1997cited by this paper
• Interleukin-2 secretion by KHT sarcoma cells leads to loss of their vaccine potential

  1997cited by this paper
• The ETS-domain transcription factor family.

  1997cited by this paper
• Serological analysis of human tumor antigens: molecular definition and implications.

  1997cited by this paper
• HIV associated tuberculosis

  1997cited by this paper
• Flow-cytometric determination of peptide-class I complex formation. Identification of p53 peptides that bind to HLA-A2.

  1994cited by this paper
• Direct analysis of tumor-associated peptide antigens.

  1994cited by this paper

• Double Agent: SPDEF Gene with Both Oncogenic and Tumor-Suppressor Functions in Breast Cancer

  2020cites this paper
• Opportunities for Antigen Discovery in Metastatic Breast Cancer

  2020cites this paper
• High SPDEF may identify patients who will have a prolonged response to androgen deprivation therapy

  2014cites this paper
• Prostate derived ETS factor (PDEF): a putative tumor metastasis suppressor.

  2011cites this paper
• Self-assembled nanoparticles as new smart contrast agents for magnetic resonance imaging

  2010cites this paper