Divergence in enzyme regulation between Caenorhabditis elegans and human tyrosine hydroxylase, the key enzyme in the synthesis of dopamine.

No abstract is available for this paper.

• Publication year

  2011

• Venue

  Biochemical Journal

• Publication date

  2011-02-15

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1042/BJ20101561PMID 21087208
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Complementary developmental expression of the two tyrosine hydroxylase transcripts in zebrafish

  2009cited by this paper
• Three-way Interaction between 14-3-3 Proteins, the N-terminal Region of Tyrosine Hydroxylase, and Negatively Charged Membranes*

  2009cited by this paper
• A Unique Dual Activity Amino Acid Hydroxylase in Toxoplasma gondii

  2009cited by this paper
• EPAC-INDUCED ALTERATIONS IN THE PROTEOME OF HUMAN SH-SY5Y NEUROBLASTOMA CELLS

  2009cited by this paper
• Direct Binding of GTP Cyclohydrolase and Tyrosine Hydroxylase

  2008cited by this paper
• Mutations in human monoamine‐related neurotransmitter pathway genes

  2008cited by this paper
• Selectivity and affinity determinants for ligand binding to the aromatic amino acid hydroxylases.

  2007cited by this paper
• Dopamine mediates context-dependent modulation of sensory plasticity in C. elegans.

  2007cited by this paper
• Structure of Phenylalanine Hydroxylase from Colwellia psychrerythraea 34H, a Monomeric Cold Active Enzyme with Local Flexibility around the Active Site and High Overall Stability*

  2007cited by this paper
• C. elegans sequences that control trans-splicing and operon pre-mRNA processing.

  2007cited by this paper
• Characterization of tyrosine hydroxylase from Manduca sexta.

  2007cited by this paper
• In-gel digestion for mass spectrometric characterization of proteins and proteomes

  2006cited by this paper
• C. elegans 14-3-3 proteins regulate life span and interact with SIR-2.1 and DAF-16/FOXO.

  2006cited by this paper
• 14-3-3 proteins: a historic overview.

  2006cited by this paper
• Biochemical Conservation of Recombinant Drosophila Tyrosine Hydroxylase with its Mammalian Cognates

  2005cited by this paper
• Dopamine and Glutamate Control Area-Restricted Search Behavior in Caenorhabditis elegans

  2004cited by this paper
• Tyrosine hydroxylase phosphorylation: regulation and consequences

  2004cited by this paper
• Dopamine modulates the plasticity of mechanosensory responses in Caenorhabditis elegans

  2004cited by this paper
• Effects of phosphorylation by protein kinase A on binding of catecholamines to the human tyrosine hydroxylase isoforms

  2004cited by this paper
• [C. elegans: of neurons and genes].

  2003cited by this paper
• The Caenorhabditis elegans dopaminergic system: opportunities for insights into dopamine transport and neurodegeneration.

  2003cited by this paper
• Structural comparison of bacterial and human iron-dependent phenylalanine hydroxylases: similar fold, different stability and reaction rates.

  2002cited by this paper
• Analysis of protein phosphorylation using mass spectrometry: deciphering the phosphoproteome.

  2002cited by this paper
• Role of catecholamine signaling in brain and nervous system functions: new insights from mouse molecular genetic study.

  2001cited by this paper
• A new splicing variant for human tyrosine hydroxylase in the adrenal medulla.

  2001cited by this paper
• Interaction of phosphorylated tyrosine hydroxylase with 14‐3‐3 proteins: evidence for a phosphoserine 40‐dependent association

  2001cited by this paper
• The aromatic amino acid hydroxylases.

  2000cited by this paper
• C. elegans locomotory rate is modulated by the environment through a dopaminergic pathway and by experience through a serotonergic pathway.

  2000cited by this paper
• Tyrosine hydroxylase binds tetrahydrobiopterin cofactor with negative cooperativity, as shown by kinetic analyses and surface plasmon resonance detection.

  1999cited by this paper
• Dopamine Inhibition of Human Tyrosine Hydroxylase Type 1 Is Controlled by the Specific Portion in the N‐Terminus of the Enzyme

  1999cited by this paper
• Structural Insight into the Aromatic Amino Acid Hydroxylases and Their Disease-Related Mutant Forms.

  1999cited by this paper
• Differential Regulation of Drosophila Tyrosine Hydroxylase Isoforms by Dopamine Binding and cAMP-dependent Phosphorylation*

  1999cited by this paper
• Patterning of dopaminergic neurotransmitter identity among Caenorhabditis elegans ray sensory neurons by a TGFbeta family signaling pathway and a Hox gene.

  1999cited by this paper
• Mutational Analysis of Substrate Inhibition in Tyrosine Hydroxylase

  1998cited by this paper
• Effects of phosphorylation of serine 40 of tyrosine hydroxylase on binding of catecholamines: evidence for a novel regulatory mechanism.

  1998cited by this paper
• Motor and learning dysfunction during postnatal development in mice defective in dopamine neuronal transmission

  1998cited by this paper
• New Species of Human Tyrosine Hydroxylase mRNA Are Produced in Variable Amounts in Adrenal Medulla and Are Overexpressed in Progressive Supranuclear Palsy

  1996cited by this paper
• Intricate Regulation of Tyrosine Hydroxylase Activity and Gene Expression

  1996cited by this paper
• Tyrosine hydroxylase.

  1995cited by this paper
• Tyrosine hydroxylase: human isoforms, structure and regulation in physiology and pathology.

  1995cited by this paper
• Targeted disruption of the tyrosine hydroxylase gene reveals that catecholamines are required for mouse fetal development

  1995cited by this paper
• Regulation of recombinant human tyrosine hydroxylase isozymes by catecholamine binding and phosphorylation. Structure/activity studies and mechanistic implications.

  1992cited by this paper
• Activation and Multiple‐Site Phosphorylation of Tyrosine Hydroxylase in Perfused Rat Adrenal Glands

  1992cited by this paper
• Recombinant human tyrosine hydroxylase isozymes. Reconstitution with iron and inhibitory effect of other metal ions.

  1991cited by this paper
• Phenylalanine as substrate for tyrosine hydroxylase in bovine adrenal chromaffin cells.

  1990cited by this paper
• pH‐dependent release of catecholamines from tyrosine hydroxylase and the effect of phosphorylation of Ser‐40

  1990cited by this paper
• A rapid and sensitive assay for tyrosine-3-monooxygenase based upon the release of 3H2O and adsorption of [3H]-tyrosine by charcoal.

  1986cited by this paper
• A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding.

  1976cited by this paper
• Dopaminergic neurons in the nematode Caenorhabditis elegans

  1975cited by this paper
• The genetics of Caenorhabditis elegans.

  1974cited by this paper
• B. TYROSINE HYDROXYLASE

  1966cited by this paper
• The FASEB Journal • Research Communication Anabolic function of phenylalanine hydroxylase in

  year unknowncited by this paper

• Tyrosine hydroxylase- and serotonin-immunoreactive neurons in the thoracic ganglia of the Oriental fruit fly, Bactrocera dorsalis.

  2025cites this paper
• Anatomical organization of the cerebrum of the praying mantis Hierodula membranacea

  2024cites this paper
• The nematode worm C. elegans chooses between bacterial foods as if maximizing economic utility

  2023cites this paper
• Insulin signaling in dopaminergic neurons regulates extended memory formation in Caenorhabditis elegans

  2023cites this paper
• Organization of descending neurons in the brain of the desert locust.

  2023cites this paper
• Parallel pathways for serotonin biosynthesis and metabolism in C. elegans

  2022cites this paper
• Structural mechanism for tyrosine hydroxylase inhibition by dopamine and reactivation by Ser40 phosphorylation

  2022cites this paper
• Regulation of monoamine levels by typical and atypical antipsychotics in Caenorhabditis elegans mutant for Nuclear Distribution Element genes.

  2021cites this paper
• Investigating the molecular mechanisms of learning and memory using Caenorhabditis elegans

  2021cites this paper
• Tyrosine hydroxylase immunostaining in the central complex of dicondylian insects

  2021cites this paper
• Neuroprotective Effects of Salidroside on Cerebral Ischemia/Reperfusion-Induced Behavioral Impairment Involves the Dopaminergic System

  2019cites this paper
• Molecular and cellular modulators for multisensory integration in C. elegans

  2019cites this paper
• Pink1 Regulates Tyrosine Hydroxylase Expression and Dopamine Synthesis

  2018cites this paper
• A collective modulatory basis for multisensory integration in C. elegans

  2018cites this paper
• Manganese tissue accumulation and tyrosine hydroxylase immunostaining response in the Neotropical freshwater crab, Dilocarcinus pagei, exposed to manganese

  2017cites this paper
• Multiple excitatory and inhibitory neural signals converge to fine‐tune Caenorhabditis elegans feeding to food availability

  2016cites this paper
• Piperine induces autophagy by enhancing protein phosphotase 2A activity in a rotenone-induced Parkinson's disease model

  2016cites this paper
• Neuroprotective effects of 5-(4-hydroxy-3-dimethoxybenzylidene)-thiazolidinone in MPTP induced Parkinsonism model in mice.

  2015cites this paper
• Neuroprotective effects of Aceglutamide on motor function in a rat model of cerebral ischemia and reperfusion

  2015cites this paper
• Structure–Function Relationships in the Aromatic Amino Acid Hydroxylases Enzyme Family: Evolutionary Insights

  2014cites this paper
• Stabilisation of Tyrosine Hydroxylase in Nanoparticles for Enzyme Replacement Therapy

  2012cites this paper