Influence of gossypol acetic acid on the growth of human adenoid cystic carcinoma ACC-M cells and the expression of DNA methyltransferase 1.

No abstract is available for this paper.

• Publication year

  2015

• Venue

  Genetics and Molecular Research

• Publication date

  2015-10-28

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.4238/2015.October.28.6PMID 26535659
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Evaluation of the effect of l-thyroxin therapy on endothelial functions in patients with subclinical hypothyroidism

  2011cited by this paper
• AT-101 induces apoptosis in CLL B cells and overcomes stromal cell-mediated Mcl-1 induction and drug resistance.

  2009cited by this paper
• Study on the effect of gossypol combined with radiotherapy in inducing apoptosis of human cervical carcinoma HeLa cells

  2009cited by this paper
• Targeting apoptosis in the hormone‐ and drug‐resistant prostate cancer cell line, DU‐145, by gossypol/zoledronic acid combination

  2009cited by this paper
• ApoG2, a novel inhibitor of antiapoptotic Bcl‐2 family proteins, induces apoptosis and suppresses tumor growth in nasopharyngeal carcinoma xenografts

  2008cited by this paper
• Gossypol, a BH3 mimetic, induces apoptosis in chronic lymphocytic leukemia cells.

  2008cited by this paper
• Gossypol reduction of tumor growth through ROS‐dependent mitochondria pathway in human colorectal carcinoma cells

  2007cited by this paper
• Retinoblastoma pathway dysregulation causes DNA methyltransferase 1 overexpression in cancer via MAD2-mediated inhibition of the anaphase-promoting complex.

  2007cited by this paper
• Alteration of DNA methyltransferases contributes to 5'CpG methylation and poor prognosis in lung cancer.

  2007cited by this paper
• Bcl-2 antagonist apogossypol (NSC736630) displays single-agent activity in Bcl-2-transgenic mice and has superior efficacy with less toxicity compared with gossypol (NSC19048).

  2006cited by this paper
• (-)-gossypol inhibits growth and promotes apoptosis of human head and neck squamous cell carcinoma in vivo.

  2006cited by this paper
• The role of DNA methylation in cancer development.

  2006cited by this paper
• DNA methylation of multiple tumor-related genes in association with overexpression of DNA methyltransferase 1 (DNMT1) during multistage carcinogenesis of the pancreas.

  2006cited by this paper
• (-)-Gossypol acts directly on the mitochondria to overcome Bcl-2- and Bcl-X(L)-mediated apoptosis resistance.

  2005cited by this paper
• Up-regulation of DNA methyltransferases DNMT1, 3A, and 3B in myelodysplastic syndrome.

  2005cited by this paper
• Opposite alterations of DNA methyltransferase gene expression in endometrioid and serous endometrial cancers.

  2005cited by this paper
• Increased DNA methyltransferase 1 (DNMT1) protein expression correlates significantly with poorer tumor differentiation and frequent DNA hypermethylation of multiple CpG islands in gastric cancers.

  2004cited by this paper
• In vitro Effects of the BH3 Mimetic, (−)-Gossypol, on Head and Neck Squamous Cell Carcinoma Cells

  2004cited by this paper
• Epigenetic alterations in head and neck cancer: Prevalence, clinical significance, and implications

  2004cited by this paper
• Molecular mechanism of gossypol-induced cell growth inhibition and cell death of HT-29 human colon carcinoma cells.

  2003cited by this paper
• Epigenomic Stress Response

  2003cited by this paper
• CpG island hypermethylation and tumor suppressor genes: a booming present, a brighter future

  2002cited by this paper
• Expression of DNA methyltransferases DNMT1, 3A, and 3B in normal hematopoiesis and in acute and chronic myelogenous leukemia.

  2001cited by this paper
• DNA methyltransferase expression and DNA methylation of CPG islands and peri‐centromeric satellite regions in human colorectal and stomach cancers

  2001cited by this paper
• DNA methyltransferase Dnmt1 associates with histone deacetylase activity

  2000cited by this paper
• Cytotoxic effect of gossypol on colon carcinoma cells.

  2000cited by this paper
• Stereo-specific cytotoxic effects of gossypol enantiomers and gossypolone in tumour cell lines.

  1999cited by this paper

• Dual effects of gossypol on human hepatocellular carcinoma via endoplasmic reticulum stress and autophagy.

  2019cites this paper
• Pharmacokinetics, biodistribution, and bioavailability of gossypol-loaded Pluronic ® F127 nanoparticles

  2018cites this paper
• Targeting EP4 downstream c‐Jun through ERK1/2‐mediated reduction of DNMT1 reveals novel mechanism of solamargine‐inhibited growth of lung cancer cells

  2016cites this paper