Immunotherapy of C3H/HeJ mammary adenocarcinoma with interleukin-2, mistletoe lectin or their combination. effects on tumour growth, capillary leakage and nitric oxide (NO) production.

No abstract is available for this paper.

• Publication year

  2001

• Venue

  European Journal of Cancer

• Publication date

  2001-10-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/S0959-8049(01)00156-3PMID 11576848
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Inability of galactoside-specific mistletoe lectin to inhibit N-methyl-N-nitrosourea-induced tumor development in the urinary bladder of rats and to mediate a local cellular immune response after long-term administration

  2012cited by this paper
• Lectins and Cancer

  2011cited by this paper
• Subkutane Manifestationen eines zentrozytischen Non-Hodgkin-Lymphoms an Injektionsstellen eines Mistelpräparats

  2008cited by this paper
• Role of nitric oxide in carcinogenesis and tumour progression.

  2001cited by this paper
• Evidence for Stimulation of Tumor Proliferation in Cell Lines and Histotypic Cultures by Clinically Relevant Low Doses of the Galactoside-Binding Mistletoe Lectin, A Component of Proprietary Extracts

  2001cited by this paper
• Biological Information Transfer Beyond the Genetic Code: The Sugar Code

  2000cited by this paper
• Nitric oxide inhibits inducible nitric oxide synthase mRNA expression in RAW 264.7 macrophages.

  2000cited by this paper
• Long-term administration of galactoside-specific mistletoe lectin in an animal model: no protection against N -butyl-N -(4-hydroxybutyl)-nitrosamine-induced urinary bladder carcinogenesis in rats and no induction of a relevant local cellular immune response

  2000cited by this paper
• Recombinant mistletoe lectin (rML) is successful in treating human ovarian cancer cells transplanted into severe combined immunodeficient (SCID) mice.

  2000cited by this paper
• Nitric oxide promotes murine mammary tumour growth and metastasis by stimulating tumour cell migration, invasiveness and angiogenesis

  2000cited by this paper
• Lectin-induced nitric oxide production.

  1999cited by this paper
• Nitric‐oxide production by murine mammary adenocarcinoma cells promotes tumor‐cell invasiveness

  1999influential reference
• Tryptophan 409 Controls the Activity of Neuronal Nitric-oxide Synthase by Regulating Nitric Oxide Feedback Inhibition*

  1999cited by this paper
• Animal Model Nitric Oxide Synthase Inhibition by N G -Nitro- L Arginine Methyl Ester Inhibits Tumor-Induced Angiogenesis in Mammary Tumors

  1999cited by this paper
• Inhibitory effects of nitric oxide donors on nitric oxide synthesis in rat gastric myenteric plexus.

  1998cited by this paper
• Effect of a Recombinant Lectin, Viscum album Agglutinin on the Secretion of Interleukin-12 in Cultured Human Peripheral Blood Mononuclear Cells and on NK-Cell-Mediated Cytotoxicity of Rat Splenocytes in vitro and in vivo

  1998cited by this paper
• Efficiency of treatment with galactoside-specific lectin from mistletoe against rat glioma.

  1998cited by this paper
• Effects of a standardized mistletoe preparation on metastatic B16 melanoma colonization in murine lungs.

  1998cited by this paper
• Mistletoe lectin I-induced effects on human cytotoxic lymphocytes. I. Synergism with IL-2 in the induction of enhanced LAK cytotoxicity.

  1998cited by this paper
• [Subcutaneous manifestations of a centrocytic non-Hodgkin lymphoma at the injection site of a mistletoe preparation].

  1998cited by this paper
• Actions of lectins from the mushroom Tricholoma mongolicum on macrophages, splenocytes and life-span in sarcoma-bearing mice.

  1997cited by this paper
• The role of active inducible nitric oxide synthase expression in the pathogenesis of capillary leak syndrome resulting from interleukin-2 therapy in mice.

  1997influential reference
• NG-nitro-L-arginine methyl ester, an inhibitor of nitric oxide synthesis, ameliorates interleukin 2-induced capillary leakage and reduces tumour growth in adenocarcinoma-bearing mice.

  1996cited by this paper
• Mistletoe lectins I, II and III induce the production of cytokines by cultured human monocytes.

  1996cited by this paper
• Nitrotyrosine as biomarker for reactive nitrogen species.

  1996cited by this paper
• A plant lectin derived from Viscum album induces cytokine gene expression and protein production in cultures of human peripheral blood mononuclear cells.

  1995cited by this paper
• Use of lectins as diagnostic and therapeutic tools for cancer.

  1995cited by this paper
• Direct and reversible inhibition of endothelial nitric oxide synthase by nitric oxide.

  1995cited by this paper
• Negative modulation of nitric oxide synthase by nitric oxide and nitroso compounds.

  1995cited by this paper
• NG-Nitro‐L-Arginine Methyl Ester, an Inhibitor of Nitric Oxide Synthesis, Ameliorates Interleukin‐2-induced Capillary Leak Syndrome in Healthy Mice

  1995cited by this paper
• [Immunoactive action of mistletoe lectin-1 in relation to dose].

  1994cited by this paper
• Sustained Oral Indomethacin and Ranitidine with Intermittent Continuous Infusion Interleukin-2 in Advanced Renal Cell Carcinoma

  1993cited by this paper
• Mistletoe (viscum album) lectins as cytokine inducers and immunoadjuvant in tumor therapy. A review.

  1993cited by this paper
• Eradication of spontaneous and experimental adenocarcinoma metastases with chronic indomethacin and intermittent IL‐2 therapy

  1993influential reference
• Feedback inhibition of nitric oxide synthase activity by nitric oxide

  1993cited by this paper
• Sustained indomethacin and ranitidine with intermittent continuous infusion interleukin-2 in advanced malignant melanoma: a phase II study.

  1993cited by this paper
• Behavior of lymphocyte subsets and expression of activation markers in response to immunotherapy with galactoside-specific lectin from mistletoe in breast cancer patients

  1992cited by this paper
• The galactoside-specific lectin from mistletoe as biological response modifier.

  1992cited by this paper
• Immunotherapeutic effects of purified mistletoe lectin (ML-I) on murine large cell lymphoma

  1991cited by this paper
• Influence of treatment with the immunomodulatory effective dose of the beta-galactoside-specific lectin from mistletoe on tumor colonization in BALB/c-mice for two experimental model systems.

  1991cited by this paper
• Increased Secretion of Tumor Necrosis Factor α, Interleukin 1, and Interleukin 6 by Human Mononuclear Cells Exposed to β-Galactoside-specific Lectin from Clinically Applied Mistletoe Extract

  1990cited by this paper
• Cure of human melanoma lung metastases in nude mice with chronic indomethacin therapy combined with multiple rounds of IL-2: characteristics of killer cells generated in situ.

  1990cited by this paper
• Influence of type of linkage and spacer on the interaction of beta-galactoside-binding proteins with immobilized affinity ligands.

  1990cited by this paper
• Increased secretion of tumor necrosis factors alpha, interleukin 1, and interleukin 6 by human mononuclear cells exposed to beta-galactoside-specific lectin from clinically applied mistletoe extract.

  1990cited by this paper
• Modulatory potency of the beta-galactoside-specific lectin from mistletoe extract (Iscador) on the host defense system in vivo in rabbits and patients.

  1989cited by this paper
• Cure of B16F10 melanoma lung metastasis in mice by chronic indomethacin therapy combined with repeated rounds of interleukin 2: characteristics of killer cells generated in situ.

  1988cited by this paper
• A progress report on the treatment of 157 patients with advanced cancer using lymphokine-activated killer cells and interleukin-2 or high-dose interleukin-2 alone.

  1987cited by this paper
• Extravasation of intravascular fluid mediated by the systemic administration of recombinant interleukin 2.

  1986cited by this paper
• Regression of established pulmonary metastases and subcutaneous tumor mediated by the systemic administration of high-dose recombinant interleukin 2

  1985cited by this paper
• Unproven methods of cancer treatment

  year unknowncited by this paper
• Endothelial Nitric Oxide Synthase Expression by Nitric Oxide

  year unknowncited by this paper

• Antitumor Activity of a Lectin Purified from Punica Granatum Pulps against Ehrlich Ascites Carcinoma (EAC) Cells.

  2023cites this paper
• Komplementäre Methoden in der Tumortherapie

  2020cites this paper
• Quantitative analysis of receptor-mediated uptake and pro-apoptotic activity of mistletoe lectin-1 by high content imaging

  2018cites this paper
• Haustorium 41 July 2002-1-HAUSTORIUM Parasitic Plants Newsletter Official Organ of the International Parasitic Plant Society July 2002 Number 41

  2017cites this paper
• Viscum album (L.) in experimental animal tumors: A meta-analysis

  2017influential citation
• Nanocarreadores lipossomais contendo a lectina BVL : influência de polímeros glicosilados na dinâmica molecular

  2017cites this paper
• Lectins from Medicinal Plants: Bioeffectors with Diverse Activities

  2014cites this paper
• Algal lectins as promising biomolecules for biomedical research

  2013cites this paper
• Tumor-InducedCD8+T-CellDysfunctioninLungCancerPatients

  2012cites this paper
• Tumor-Induced CD8+ T-Cell Dysfunction in Lung Cancer Patients

  2012cites this paper
• Activation-induced cell death of memory CD8+ T cells from pleural effusion of lung cancer patients is mediated by the type II Fas-induced apoptotic pathway

  2012cites this paper
• The antitumoral effect of the American mistletoe Phoradendron serotinum (Raf.) M.C. Johnst. (Viscaceae) is associated with the release of immunity-related cytokines.

  2012cites this paper
• Interleukin-11-induced capillary leak syndrome in primary hepatic carcinoma patients with thrombocytopenia

  2011cites this paper
• Clinical Response of Metastatic Breast Cancer to Multi-targeted Therapeutic Approach: A Single Case Report

  2011cites this paper
• In vitro and in vivo anti-tumor effects of novel Span 80 vesicles containing immobilized Eucheuma serra agglutinin.

  2010cites this paper
• Pflanzliche Lectine: Vorkommen, Eigenschaften, Analytik und Bewertung ihrer immunmodulatorischen Aktivität

  2010cites this paper
• THE ROLE OF PLANT LECTINS IN CANCER TREATMENT

  2010cites this paper
• Cytotoxic Activities of Extracts and Compounds from Viscum coloratum and its Transformation Products by Rhodobacter sphaeroides

  2009cites this paper
• Viscum album L. extracts in breast and gynaecological cancers: a systematic review of clinical and preclinical research

  2009cites this paper
• Tumorwachstumsstimulation durch Mistelpräparate? Fakten und Artefakte

  2008influential citation
• Korean mistletoe lectin (KML-IIU) and its subchains induce nitric oxide (NO) production in murine macrophage cells.

  2008cites this paper
• Cytotoxic effects of the Viscum album L. extract on Ehrlich tumour cells in vivo

  2008cites this paper
• Growth/adhesion-regulatory tissue lectin galectin-3: stromal presence but not cytoplasmic/nuclear expression in tumor cells as a negative prognostic factor in breast cancer.

  2007cites this paper
• Kapitel 6 – Komplementäre Therapieverfahren in der Onkologie

  2006cites this paper
• Kapitel 8 – Komplementäre Therapieverfahren

  2006cites this paper
• AB-type lectin (toxin/agglutinin) from mistletoe: differences in affinity of the two galactoside-binding Trp/Tyr-sites and regulation of their functionality by monomer/dimer equilibrium.

  2006cites this paper
• ADVERSE DRUG REACTIONS WITH MISTLETOE THERAPY IN CANCER PATIENTS - A SYSTEMATIC REVIEW

  2005cites this paper
• Lectins as Bioactive Plant Proteins: A Potential in Cancer Treatment

  2005cites this paper
• Metastatic melanoma

  2005cites this paper
• Assessment of a combined, adenovirus-mediated oncolytic and immunostimulatory tumor therapy.

  2005cites this paper
• Monomer/dimer equilibrium of the AB-type lectin from mistletoe enables combination of toxin/agglutinin activities in one protein: analysis of native and citraconylated proteins by ultracentrifugation/gel filtration and cell biological consequences of dimer destabilization.

  2005cites this paper
• Is Biochemotherapy the Future

  2005cites this paper
• Antitumor activity of Cratylia mollis lectin encapsulated into liposomes.

  2004influential citation
• Astroglia Induce Cytotoxic Effects on Brain Tumors via a Nitric Oxide-Dependent Pathway Both in Vitro and in Vivo

  2004cites this paper
• Glycomic profiling of developmental changes in bovine testis by lectin histochemistry and further analysis of the most prominent alteration on the level of the glycoproteome by lectin blotting and lectin affinity chromatography.

  2004cites this paper
• Chemical Biology of the Sugar Code

  2004cites this paper
• Lectins and glycoconjugates in drug delivery and targeting.

  2004cites this paper
• Combined analysis of tumor growth pattern and expression of endogenous lectins as a prognostic tool in primary testicular cancer and its lung metastases.

  2003cites this paper
• Intracellular Transport of Plant Toxins Ricin and Viscumin from Different Plasma Membrane Sites

  2003cites this paper
• Suitability of binary mixtures of water with aprotic solvents to turn hydroxyl protons of carbohydrate ligands into conformational sensors in NOE and transferred NOE experiments

  2003cites this paper
• Atividade abtitumoral de lectina de Cratylia mollis encapsulada em lipossomas

  2003influential citation
• Mistletoe in cancer - a systematic review on controlled clinical trials.

  2003cites this paper
• Presentation of NO-metabolites (nitrate/nitrite) in blood serum and pleural effusions from cancer patients with pleurisy.

  2002cites this paper
• Lektinbezogene Mistelanwendung: Experimentelle Therapieform mit präklinisch belegtem Risikopotenzial

  2002cites this paper
• [Lectin-related use of mistletoe: an experimental form of treatment with preclinically demonstrated potential risks].

  2002cites this paper
• Plant lectins: Occurrence, biochemistry, functions and applications

  2001cites this paper
• Probing the cons and pros of lectin-induced immunomodulation: case studies for the mistletoe lectin and galectin-1.

  2001cites this paper