MSX1 Modulates RLR-Mediated Innate Antiviral Signaling by Facilitating Assembly of TBK1-Associated Complexes

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Journal of Immunology

• Publication date

  2016-07-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.4049/jimmunol.1600039PMID 27194789
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• DYRK2 Negatively Regulates Type I Interferon Induction by Promoting TBK1 Degradation via Ser527 Phosphorylation

  2015cited by this paper
• TRIM38 Negatively Regulates TLR3/4-Mediated Innate Immune and Inflammatory Responses by Two Sequential and Distinct Mechanisms

  2015cited by this paper
• Genome engineering using CRISPR-Cas9 system.

  2015cited by this paper
• MSX1 inhibits cell migration and invasion through regulating the Wnt/β-catenin pathway in glioblastoma

  2015cited by this paper
• ECSIT Bridges RIG-I-Like Receptors to VISA in Signaling Events of Innate Antiviral Responses

  2014cited by this paper
• Novel nonsense mutation in MSX1 in familial nonsyndromic oligodontia: subcellular localization and role of homeodomain/MH4.

  2014cited by this paper
• Adding to the STING.

  2014cited by this paper
• Krüppel-like factor 4 negatively regulates cellular antiviral immune response

  2014cited by this paper
• MSX1 gene and nonsyndromic oral clefts in a Southern Brazilian population

  2013cited by this paper
• STING recognition of cytoplasmic DNA instigates cellular defense.

  2013cited by this paper
• Genome engineering using the CRISPR-Cas9 system

  2013cited by this paper
• NLRP4 negatively regulates type I interferon signaling by targeting the kinase TBK1 for degradation via the ubiquitin ligase DTX4

  2012cited by this paper
• Functional Dissection of the TBK1 Molecular Network

  2011cited by this paper
• The Msx1 Homeoprotein Recruits Polycomb to the Nuclear Periphery during Development.

  2011cited by this paper
• PIAS1 negatively regulates ubiquitination of Msx1 homeoprotein independent of its SUMO ligase activity

  2011cited by this paper
• The MSX1 homeobox transcription factor is a downstream target of PHOX2B and activates the Delta-Notch pathway in neuroblastoma

  2010cited by this paper
• MSX1 induces the Wnt pathway antagonist genes DKK1, DKK2, DKK3, and SFRP1 in neuroblastoma cells, but does not block Wnt3 and Wnt5A signalling to DVL3.

  2010cited by this paper
• Glycogen synthase kinase 3β regulates IRF3 transcription factor-mediated antiviral response via activation of the kinase TBK1.

  2010cited by this paper
• The E3 Ubiquitin Ligase RNF5 Targets Virus-Induced Signaling Adaptor for Ubiquitination and Degradation

  2010cited by this paper
• WDR5 is essential for assembly of the VISA-associated signaling complex and virus-triggered IRF3 and NF-κB activation

  2009cited by this paper
• The ubiquitin ligase RNF5 regulates antiviral responses by mediating degradation of the adaptor protein MITA.

  2009cited by this paper
• The MSX1 homeobox transcription factor is a downstream target of PHOX2B and activates the Delta-Notch pathway in neuroblastoma.

  2008cited by this paper
• The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation.

  2008cited by this paper
• Negative regulation of MDA5- but not RIG-I-mediated innate antiviral signaling by the dihydroxyacetone kinase

  2007cited by this paper
• SINTBAD, a novel component of innate antiviral immunity, shares a TBK1‐binding domain with NAP1 and TANK

  2007cited by this paper
• Modulation of the Interferon Antiviral Response by the TBK1/IKKi Adaptor Protein TANK*

  2007influential reference
• Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response

  2006cited by this paper
• NAK-Associated Protein 1 Participates in Both the TLR3 and the Cytoplasmic Pathways in Type I IFN Induction1

  2006cited by this paper
• Regulation of antiviral responses by a direct and specific interaction between TRAF3 and Cardif

  2006cited by this paper
• PIAS1 confers DNA-binding specificity on the Msx1 homeoprotein.

  2006cited by this paper
• Combined deficiencies of Msx1 and Msx2 cause impaired patterning and survival of the cranial neural crest

  2005cited by this paper
• IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction

  2005cited by this paper
• Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus

  2005cited by this paper
• VISA is an adapter protein required for virus-triggered IFN-beta signaling.

  2005cited by this paper
• Identification and Characterization of MAVS, a Mitochondrial Antiviral Signaling Protein that Activates NF-κB and IRF3

  2005cited by this paper
• SIKE is an IKKε/TBK1‐associated suppressor of TLR3‐ and virus‐triggered IRF‐3 activation pathways

  2005cited by this paper
• Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3.

  2005cited by this paper
• SIKE is an IKK epsilon/TBK1-associated suppressor of TLR3- and virus-triggered IRF-3 activation pathways.

  2005cited by this paper
• Differential Requirement for TANK-binding Kinase-1 in Type I Interferon Responses to Toll-like Receptor Activation and Viral Infection

  2004cited by this paper
• The Roles of Two IκB Kinase-related Kinases in Lipopolysaccharide and Double Stranded RNA Signaling and Viral Infection

  2004cited by this paper
• Triggering the Interferon Antiviral Response Through an IKK-Related Pathway

  2003cited by this paper
• IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway.

  2003cited by this paper
• Identification of NAP1, a regulatory subunit of IkappaB kinase-related kinases that potentiates NF-kappaB signaling.

  2003cited by this paper
• IFN-regulatory factor 3-dependent gene expression is defective in Tbk1-deficient mouse embryonic fibroblasts

  2003cited by this paper
• Identification of NAP1, a Regulatory Subunit of IκB Kinase-Related Kinases That Potentiates NF-κB Signaling

  2003cited by this paper
• Deficiency of T2K leads to apoptotic liver degeneration and impaired NF‐κB‐dependent gene transcription

  2000cited by this paper
• NAK is an IkappaB kinase-activating kinase.

  2000cited by this paper
• NAK is an IκB kinase-activating kinase

  2000cited by this paper
• Msx1 antagonizes the myogenic activity of Pax3 in migrating limb muscle precursors.

  1999cited by this paper
• NF‐κB activation by a signaling complex containing TRAF2, TANK and TBK1, a novel IKK‐related kinase

  1999cited by this paper
• IKK-γ is an essential regulatory subunit of the IκB kinase complex

  1998cited by this paper
• IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex.

  1998cited by this paper
• A role for the Msx-1 homeodomain in transcriptional regulation: residues in the N-terminal arm mediate TATA binding protein interaction and transcriptional repression.

  1996cited by this paper
• MSX1 inhibits myoD expression in fibroblast x 10T1/2 cell hybrids.

  1995cited by this paper
• Msx1 deficient mice exhibit cleft palate and abnormalities of craniofacial and tooth development

  1994cited by this paper

• Homeobox protein MSX-1 restricts hepatitis B virus by promoting ubiquitin-independent proteasomal degradation of HBx protein

  2025cites this paper
• Gallic acid inhibits EMCV infection via targeting the interaction between TBK1 and IRF3 to promote IFN-β expression

  2025cites this paper
• Intrahepatic homeobox protein MSX-1 is a novel host restriction factor of hepatitis B virus

  2024cites this paper
• Immune signature of gene expression pattern shared by autism spectrum disorder and Huntington's disease

  2024cites this paper
• DDX5 inhibits type I IFN production by promoting degradation of TBK1 and disrupting formation of TBK1 − TRAF3 complex

  2023cites this paper
• Mitochondrial DNA-triggered innate immune response: mechanisms and diseases

  2023cites this paper
• African Swine Fever Virus E184L Protein Interacts with Innate Immune Adaptor STING to Block IFN Production for Viral Replication and Pathogenesis.

  2023cites this paper
• Regulation of antiviral innate immune signaling and viral evasion following viral genome sensing

  2021cites this paper
• Innate Immune Responses to Herpesvirus Infection

  2021cites this paper
• In silico characterization and structural modeling of a homeobox protein MSX1 from Homo sapiens

  2021cites this paper
• Deciphering the pathways to antiviral innate immunity and inflammation.

  2020cites this paper
• Foot-and-Mouth Disease Virus 3A Protein Causes Upregulation of Autophagy-Related Protein LRRC25 To Inhibit the G3BP1-Mediated RIG-Like Helicase-Signaling Pathway

  2020cites this paper
• Thioredoxin 2 Negatively Regulates Innate Immunity to RNA Viruses by Disrupting the Assembly of the Virus-Induced Signaling Adaptor Complex

  2020cites this paper
• G3BP1 inhibits RNA virus replication by positively regulating RIG-I-mediated cellular antiviral response

  2019cites this paper
• TANK-binding kinase 1 as a novel therapeutic target for viral diseases

  2019influential citation
• The Membrane-Associated MARCH E3 Ligase Family: Emerging Roles in Immune Regulation

  2019cites this paper
• DDX56 inhibits type I interferon by disrupting assembly of IRF3–IPO5 to inhibit IRF3 nucleus import

  2019cites this paper
• Cytoplasmic Mechanisms of Recognition and Defense of Microbial Nucleic Acids.

  2018cites this paper
• The methyltransferase PRMT6 attenuates antiviral innate immunity by blocking TBK1–IRF3 signaling

  2018cites this paper
• TMED2 Potentiates Cellular IFN Responses to DNA Viruses by Reinforcing MITA Dimerization and Facilitating Its Trafficking.

  2018cites this paper
• Multifaceted roles of TRIM38 in innate immune and inflammatory responses

  2017cites this paper
• Mitochondrial E3 ligase MARCH5 regulates FUNDC1 to fine‐tune hypoxic mitophagy

  2017cites this paper
• TRIM8 Negatively Regulates TLR3/4-Mediated Innate Immune Response by Blocking TRIF–TBK1 Interaction

  2017cites this paper
• PKACs attenuate innate antiviral response by phosphorylating VISA and priming it for MARCH5-mediated degradation

  2017cites this paper
• Transcriptomic Analysis of the Innate Antiviral Immune Response in Porcine Intestinal Epithelial Cells: Influence of Immunobiotic Lactobacilli

  2017cites this paper
• Human Cytomegalovirus Tegument Protein UL82 Inhibits STING-Mediated Signaling to Evade Antiviral Immunity.

  2017cites this paper
• GPATCH3 negatively regulates RLR-mediated innate antiviral responses by disrupting the assembly of VISA signalosome

  2017cites this paper
• Sumoylation Promotes the Stability of the DNA Sensor cGAS and the Adaptor STING to Regulate the Kinetics of Response to DNA Virus.

  2016cites this paper