Collagen-induced arthritis development requires alpha beta T cells but not gamma delta T cells: studies with T cell-deficient (TCR mutant) mice.

No abstract is available for this paper.

• Publication year

  1999

• Venue

  International Immunology

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 10383939
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• High antibody response to autologous type II collagen is restricted to H-2q

  2004cited by this paper
• B cell‐deficient mice do not develop type II collagen‐induced arthritis (CIA)

  1998cited by this paper
• Adoptively transferred EAE in gamma delta T cell-knockout mice.

  1998cited by this paper
• Aggravation of murine experimental allergic encephalomyelitis by administration of T-cell receptor gammadelta-specific antibody.

  1997cited by this paper
• An innate view of gamma delta T cells.

  1997cited by this paper
• Antibodies to type II collagen in early rheumatoid arthritis. Correlation with disease progression.

  1996cited by this paper
• Natural autoantibodies.

  1995cited by this paper
• Anti-C5 monoclonal antibody therapy prevents collagen-induced arthritis and ameliorates established disease.

  1995cited by this paper
• Peripheral lymphoid development and function in TCR mutant mice.

  1994cited by this paper
• Immunoglobulin synthesis and generalized autoimmunity in mice congenitally deficient in alpha beta(+) T cells.

  1994cited by this paper
• Local anti-type II collagen antibody production in rheumatoid arthritis synovial fluid. Evidence for an HLA-DR4-restricted IgG response.

  1994cited by this paper
• CD4+ T cells from collagen‐induced arthritic mice are essential to transfer arthritis into severe combined immunodeficient mice

  1994cited by this paper
• Exacerbation of established collagen-induced arthritis in mice treated with an anti-T cell receptor antibody.

  1994cited by this paper
• Resistance to collagen‐induced arthritis in rats and rhesus monkeys after immunization with attenuated type II collagen

  1993cited by this paper
• T cell receptor delta gene mutant mice: independent generation of alpha beta T cells and programmed rearrangements of gamma delta TCR genes.

  1993cited by this paper
• Prevention of collagen-induced arthritis with an antibody to gp39, the ligand for CD40.

  1993cited by this paper
• Prevention of collagen induced arthritis in mice by treatment with an antibody directed against the T cell receptor alpha beta framework.

  1992cited by this paper
• Mutations in T-cell antigen receptor genes alpha and beta block thymocyte development at different stages.

  1992cited by this paper
• Genetic, hormonal and behavioural influence on spontaneously developing arthritis in normal mice

  1992cited by this paper
• Characterization of a spontaneously occurring arthritis in male DBA/1 mice.

  1992cited by this paper
• Treatment of collagen-induced arthritis in rats with a monoclonal antibody against the alpha/beta T cell antigen receptor.

  1991cited by this paper
• Transgenic mice expressing human tumour necrosis factor: a predictive genetic model of arthritis.

  1991cited by this paper
• Anti‐T cell receptor antibody treatment of rats with established autologous collagen‐induced arthritis: suppression of arthritis without reduction of anti‐type II collagen autoantibody levels

  1991cited by this paper
• Analysis of type II collagen‐reactive T cells in the mouse I. Different regulation of autoreactive vs. non‐autoreactive anti‐type II collagen T cells in the DBA/1 mouse

  1990cited by this paper
• Cytokine‐related syndrome following injection of anti‐CD3 monoclonal antibody: Further evidence for transient in vivo T cell activation

  1990cited by this paper
• Secretion of antibodies to types I and II collagen by synovial tissue cells in patients with rheumatoid arthritis.

  1989cited by this paper
• Origin of the autoreactive anti-type II collagen response. II. Specificities, antibody isotypes and usage of V gene families of anti-type II collagen B cells.

  1989cited by this paper
• Persistence of collagen type II-specific T-cell clones in the synovial membrane of a patient with rheumatoid arthritis.

  1989cited by this paper
• Isolation of CD4-CD8-mycobacteria-reactive T lymphocyte clones from rheumatoid arthritis synovial fluid

  1989cited by this paper
• Nature of the type II collagen autoimmunity in mice susceptible to collagen-induced arthritis.

  1988cited by this paper
• Immunogenetics of type II collagen autoimmunity and susceptibility to collagen arthritis.

  1988cited by this paper
• The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis.

  1987cited by this paper
• Experimental arthritis in a nonhuman primate. I. Induction by bovine type II collagen.

  1986cited by this paper
• Collagen antibodies in rheumatoid arthritis. Significance of antibodies to denatured collagen and their association with HLA-DR4.

  1986cited by this paper
• T Lymphocytes in Collagen II‐Induced Arthritis in Mice

  1985cited by this paper
• Prevention of type II collagen-induced arthritis by in vivo treatment with anti-L3T4

  1985cited by this paper
• IgG and IgM antibody to native type II collagen in rheumatoid arthritis serum and synovial fluid. Evidence for the presence of collagen-anticollagen immune complexes in synovial fluid.

  1984cited by this paper
• Suppressive effects of anti-mu serum on the development of collagen arthritis in rats.

  1984cited by this paper
• Serum transfer of collagen-induced arthritis in mice

  1983cited by this paper
• Type II collagen-induced arthritis in rats. Passive transfer with serum and evidence that IgG anticollagen antibodies can cause arthritis

  1982cited by this paper
• Incidence and correlation between serum IgG and IgM antibodies to native type II collagen in patients with chronic inflammatory arthritis.

  1981cited by this paper
• Type II collagen-induced arthritis in mice. I. Major histocompatibility complex (I region) linkage and antibody correlates

  1981cited by this paper
• Immunisation against heterologous type II collagen induces arthritis in mice

  1980cited by this paper
• Humoral and cellular sensitivity to collagen in type II collagen-induced arthritis in rats.

  1978cited by this paper
• Autoimmunity to type II collagen an experimental model of arthritis

  1977cited by this paper

• Fc-enhanced anti-CCR6 antibody elicits robust therapeutic effects across multiple autoimmune diseases

  2026cites this paper
• Critical roles of the E3 ubiquitin ligase FBW7 in B‐cell response and the pathogenesis of experimental autoimmune arthritis

  2021cites this paper
• Endophilin A2 deficiency protects rodents from autoimmune arthritis by modulating T cell activation

  2021cites this paper
• The Role of Gamma Delta T Cells in Autoimmune Rheumatic Diseases

  2020cites this paper
• IL-23 in arthritic and inflammatory pain development in mice

  2020cites this paper
• CD4+CCR6+ T cells, but not γδ T cells, are important for the IL‐23R‐dependent progression of antigen‐induced inflammatory arthritis in mice

  2019cites this paper
• Targeting IgG in Arthritis: Disease Pathways and Therapeutic Avenues

  2018cites this paper
• Protective Role of the MER Tyrosine Kinase via Efferocytosis in Rheumatoid Arthritis Models

  2018cites this paper
• Germinal Center B Cells Are Essential for Collagen‐Induced Arthritis

  2018cites this paper
• Therapeutic Effects of a TANK‐Binding Kinase 1 Inhibitor in Germinal Center–Driven Collagen‐Induced Arthritis

  2018cites this paper
• Chronic Active Arthritis Driven by Macrophages Without Involvement of T Cells

  2018cites this paper
• Inactivation of the KSRP gene modifies collagen antibody induced arthritis

  2017cites this paper
• The tyrosine kinase inhibitor tyrphostin AG126 reduces activation of inflammatory cells and increases Foxp3+ regulatory T cells during pathogenesis of rheumatoid arthritis.

  2016cites this paper
• Head-to-head comparison of protocol modifications for the generation of collagen-induced arthritis in a specific-pathogen free facility using DBA/1 mice.

  2016cites this paper
• Investigation of T cell driven arthritis induced by mannan in ZAP70 mutated SKG mice

  2016cites this paper
• Collagen epitope expression on B cells is sufficient to confer tolerance to collagen-induced arthritis

  2016cites this paper
• Immune regulation by selective estrogen receptor modulators

  2015cites this paper
• Experimental African Trypanosome Infection by Needle Passage or Natural Tsetse Fly Challenge Thwarts the Development of Collagen-Induced Arthritis in DBA/1 Prone Mice via an Impairment of Antigen Specific B Cell Autoantibody Titers

  2015cites this paper
• SKEWNESS OF TCR Vβ OF PERIPHERAL BLOOD AND SYNOVIAL FLUID OF PATIENTS WITH RHEUMATOID ARTHRITIS

  2014cites this paper
• The role of natural killer cells, gamma delta T-cells and other innate immune cells in spondyloarthritis

  2013cites this paper
• Cytokine Profile of T Cells in the Joints of Rheumatoid Arthritis and Its Murine Models

  2012cites this paper
• Mucosal-associated invariant T cells promote inflammation and exacerbate disease in murine models of arthritis.

  2012cites this paper
• Genetic regulation of autoantibodies in arthritis : lessons from mouse models

  2012cites this paper
• From the DEPARTMENT OF MEDICAL BIOCHEMISTRY AND BIOPHYSICS Karolinska Institutet, Stockholm, Sweden THE GENETICS OF EXPERIMENTAL ARTHRITIS IN RODENTS

  2012cites this paper
• Th17 Cells, Not IL-17+ γδ T Cells, Drive Arthritic Bone Destruction in Mice and Humans

  2011cites this paper
• Protective effect of RC-3095, an antagonist of the gastrin-releasing peptide receptor, in experimental arthritis.

  2011cites this paper
• CD4 T cells play important roles in maintaining IL-17-producing γδ T cell subsets in naïve animals

  2011cites this paper
• IL-10 signaling in CD4+ T cells is critical for the pathogenesis of collagen-induced arthritis

  2011cites this paper
• The Role of Macrophages in Regulating Inflammation by Oxidative Burst

  2011cites this paper
• An Autoantigen-Specific, Highly Restricted T Cell Repertoire Infiltrates the Arthritic Joints of Mice in an HLA-DR1 Humanized Mouse Model of Autoimmune Arthritis

  2010cites this paper
• Curcumin attenuates inflammatory response in IL-1beta-induced human synovial fibroblasts and collagen-induced arthritis in mouse model.

  2010cites this paper
• Novel fusion protein-expressing lentiviral vectors ameliorate collagen induced arthritis

  2010cites this paper
• Gamma/delta T cells are the predominant source of interleukin-17 in affected joints in collagen-induced arthritis, but not in rheumatoid arthritis.

  2009cites this paper
• γδ T cells clonally expand, produce IL-17, and are pathogenic in collagen-induced arthritis

  2009cites this paper
• Smoking and nicotine exposure delay development of collagen-induced arthritis in mice

  2009cites this paper
• The value of animal models in predicting genetic susceptibility to complex diseases such as rheumatoid arthritis

  2009cites this paper
• A role for gamma/delta T cells in a mouse model of fracture healing.

  2009cites this paper
• The IL-12/IL-23 axis and its role in Th17 cell development, pathology and plasticity in arthritis.

  2009cites this paper
• Identification of New Loci Controlling Collagen‐induced Arthritis in Mouse Using a Partial Advanced Intercross and Congenic Strains

  2008cites this paper
• The role of collagen antibodies in mediating arthritis

  2008cites this paper
• LOOKING FOR ARTHRITIS REGULATING GENES ON MOUSE CHROMOSOME 6 & 14

  2008cites this paper
• The inhibitory CD200R is differentially expressed on human and mouse T and B lymphocytes.

  2008cites this paper
• Absence of In vitro Responses to Type II Collagen by Splenocytes from Arthritic BALB/c Mice is Possibly Caused by Intrinsic CD25+ Regulatory Cells

  2008cites this paper
• Defective Generation of a Humoral Immune Response Is Associated with a Reduced Incidence and Severity of Collagen-Induced Arthritis in Microsomal Prostaglandin E Synthase-1 Null Mice1

  2008cites this paper
• The Therapeutic Effect of Extracellular Superoxide Dismutase (EC-SOD) Mouse Embryonic Fibroblast (MEF) on Collagen-Induced Arthritis (CIA) Mice

  2008cites this paper
• Characterization of two experimental rodent models for evaluating novel drugs for rheumatoid arthritis

  2008cites this paper
• Anti-rheumatoid arthritic effect of madecassoside on type II collagen-induced arthritis in mice.

  2008cites this paper
• Treatment with total alkaloids from Radix Linderae reduces inflammation and joint destruction in type II collagen-induced model for rheumatoid arthritis.

  2007cites this paper
• Reduction of CD4 positive T cells and improvement of pathological changes of collagen-induced arthritis by FTY720.

  2007cites this paper
• Genetic Regulation of T Regulatory, CD4, and CD8 Cell Numbers by the Arthritis Severity Loci Cia5a, Cia5d, and the MHC/Cia1 in the Rat

  2007cites this paper
• Suppressive effects of Chelidonium majus methanol extract in knee joint, regional lymph nodes, and spleen on collagen-induced arthritis in mice.

  2007cites this paper
• Exacerbation of collagen-induced arthritis by oligoclonal, IL-17-producing gamma delta T cells.

  2007cites this paper
• Vaccination against IL‐17 suppresses autoimmune arthritis and encephalomyelitis

  2006cites this paper
• Antibodies against citrullinated proteins enhance tissue injury in experimental autoimmune arthritis.

  2006cites this paper
• Amelioration of Collagen-Induced Arthritis in Mice by a Saponin Fraction from Gleditsia sinensis.

  2006cites this paper
• Type IX collagen deficiency enhances the binding of cartilage-specific antibodies and arthritis severity

  2006cites this paper
• Stromal cells and osteoclasts are responsible for an exacerbated Collagen-Induced Arthritis in IFN-β deficient mice

  2006cites this paper
• Contrasting roles of plasminogen deficiency in different rheumatoid arthritis models.

  2005cites this paper
• Analysing the effect of novel therapies on cytokine expression in experimental arthritis

  2005cites this paper
• Efficient promotion of collagen antibody induced arthritis (CAIA) using four monoclonal antibodies specific for the major epitopes recognized in both collagen induced arthritis and rheumatoid arthritis.

  2005cites this paper
• Stromal cells and osteoclasts are responsible for exacerbated collagen-induced arthritis in interferon-beta-deficient mice.

  2005cites this paper
• Genetic Interactions in Eae2 Control Collagen-Induced Arthritis and the CD4+/CD8+ T Cell Ratio1

  2005cites this paper
• Regulation of arthritis by p53: critical role of adaptive immunity.

  2005cites this paper
• The plasminogen activator/plasmin system is essential for development of the joint inflammatory phase of collagen type II-induced arthritis.

  2005cites this paper
• Bystander suppression of collagen-induced arthritis in mice fed ovalbumin

  2004cites this paper
• Analysis of autoreactive T cells associated with murine collagen-induced arthritis using peptide-MHC multimers.

  2004cites this paper
• Immunomodulatory effects of sucupira (Pterodon pubescens) seed infusion on collagen-induced arthritis.

  2004cites this paper
• Collagen type II (CII)-specific antibodies induce arthritis in the absence of T or B cells but the arthritis progression is enhanced by CII-reactive T cells

  2004cites this paper
• Reduced ROS production triggers arthritis / The role of T cells in arthritis pathogenesis

  2004cites this paper
• Collagen type II-specific monoclonal antibody-induced arthritis in mice: description of the disease and the influence of age, sex, and genes.

  2003cites this paper
• Gammadelta T cells: functional plasticity and heterogeneity.

  2002cites this paper
• Reversal of tolerance induced by transplantation of skin expressing the immunodominant T cell epitope of rat type II collagen entitles development of collagen‐induced arthritis but not graft rejection

  2002cites this paper
• Glycosylation of type II collagen is of major importance for T cell tolerance and pathology in collagen‐induced arthritis

  2002cites this paper
• Differing roles for urokinase and tissue-type plasminogen activator in collagen-induced arthritis.

  2002cites this paper
• Primed B Cells Present Type‐II Collagen to T Cells

  2002cites this paper
• Syngeneic fibroblasts transfected with a plasmid encoding interleukin‐4 as non‐viral vectors for anti‐inflammatory gene therapy in collagen‐induced arthritis

  2002cites this paper
• The molecular pathogenesis of collagen-induced arthritis in mice--a model for rheumatoid arthritis.

  2002cites this paper
• Role of glycopeptide-specific T cells in collagen-induced arthritis: an example how Dost-translational modification of proteins Gay be involved in autoimmune disease

  2001cites this paper
• Interference with CD28, CD80, CD86 or CD152 in collagen-induced arthritis. Limited role of IFN-gamma in anti-B7-mediated suppression of disease.

  2001cites this paper
• Evaluation of the percentage of peripheral T cells with two different T cell receptor alpha-chains and of their potential role in autoimmunity.

  2001cites this paper
• Genetic control of collagen‐induced arthritis in a cross with NOD and C57BL/10 mice is dependent on gene regions encoding complement factor 5 and FcγRIIb and is not associated with loci controlling diabetes

  2001cites this paper
• Enhancement of collagen-induced arthritis in female mice by estrogen receptor blockage.

  2001cites this paper
• Influence of CD4 or CD8 deficiency on collagen‐induced arthritis

  2001cites this paper
• Samter's Immunologic Diseases

  2001influential citation
• T lymphocytes are not required for the spontaneous development of entheseal ossification leading to marginal ankylosis in the DBA/1 mouse.

  2000cites this paper