Dioxin induction of transgenerational inheritance of disease in zebrafish.

No abstract is available for this paper.

• Publication year

  2014

• Venue

  Molecular and Cellular Endocrinology

• Publication date

  2014-12-01

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1016/j.mce.2014.08.011PMID 25194296PMCID PMC4262573
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Effects on specific promoter DNA methylation in zebrafish embryos and larvae following benzo[a]pyrene exposure.

  2014cited by this paper
• Multigenerational effects of benzo[a]pyrene exposure on survival and developmental deformities in zebrafish larvae.

  2014cited by this paper
• Using zebrafish as a model system for studying the transgenerational effects of dioxin.

  2014influential reference
• Zebrafish sex: a complicated affair

  2013cited by this paper
• Transgenerational effects of prenatal exposure to the 1944–45 Dutch famine

  2013cited by this paper
• Benzo[a]pyrene decreases global and gene specific DNA methylation during zebrafish development.

  2013cited by this paper
• Early dioxin exposure causes toxic effects in adult zebrafish.

  2013influential reference
• Dietary exposure of mink (Mustela vison) to fish from the upper Hudson River, New York, USA: Effects on organ mass and pathology

  2013cited by this paper
• Development of an Automated Imaging Pipeline for the Analysis of the Zebrafish Larval Kidney

  2013cited by this paper
• Epigenetic Regulation of Mouse Sex Determination by the Histone Demethylase Jmjd1a

  2013cited by this paper
• Dioxin (TCDD) Induces Epigenetic Transgenerational Inheritance of Adult Onset Disease and Sperm Epimutations

  2012influential reference
• Transgenerational effects of prenatal exposure to the 1944-45 Dutch famine

  2012cited by this paper
• Transgenerational Actions of Environmental Compounds on Reproductive Disease and Identification of Epigenetic Biomarkers of Ancestral Exposures

  2012cited by this paper
• Smoking induces differential miRNA expression in human spermatozoa: A potential transgenerational epigenetic concern?

  2012cited by this paper
• Reproductive and developmental toxicity of dioxin in fish.

  2012cited by this paper
• The fetal origins of adult disease: a narrative review of the epidemiological literature

  2012cited by this paper
• Environmentally Induced Epigenetic Transgenerational Inheritance of Ovarian Disease

  2012influential reference
• Facilitating Drug Discovery: An Automated High-content Inflammation Assay in Zebrafish

  2012cited by this paper
• Zebrafish in endocrine systems: recent advances and implications for human disease.

  2011cited by this paper
• Transgenerational Epigenetic Inheritance of Longevity in C. elegans

  2011cited by this paper
• Dioxin Exposure and Cancer Risk in the Seveso Women’s Health Study

  2011cited by this paper
• Mechanistic Basis of Resistance to PCBs in Atlantic Tomcod from the Hudson River

  2011cited by this paper
• Developmental exposure to TCDD reduces fertility and negatively affects pregnancy outcomes across multiple generations.

  2011influential reference
• Comprehensive profiling of zebrafish hepatic proximal promoter CpG island methylation and its modification during chemical carcinogenesis

  2011cited by this paper
• Changes of thyroid hormone levels and related gene expression in zebrafish on early life stage exposure to triadimefon.

  2011cited by this paper
• Perinatal Exposure to Low Doses of Dioxin Can Permanently Impair Human Semen Quality

  2011cited by this paper
• Developmental dioxin exposure of either parent is associated with an increased risk of preterm birth in adult mice.

  2011cited by this paper
• Long-term food-exposure of zebrafish to PCB mixtures mimicking some environmental situations induces ovary pathology and impairs reproduction ability.

  2011cited by this paper
• Are homologies in vertebrate sex determination due to shared ancestry or to limited options?

  2010cited by this paper
• Zebrafish (Danio rerio) as a model organism for investigating endocrine disruption.

  2009cited by this paper
• Persistent adverse effects on health and reproduction caused by exposure of zebrafish to 2,3,7,8-tetrachlorodibenzo-p-dioxin during early development and gonad differentiation.

  2009influential reference
• Chemical genetic screening in the zebrafish embryo

  2009cited by this paper
• Chronic treatment with polychlorinated biphenyls (PCB) during pregnancy and lactation in the rat Part 2: Effects on reproductive parameters, on sex behavior, on memory retention and on hypothalamic expression of aromatase and 5alpha-reductases in the offspring.

  2009cited by this paper
• The aryl hydrocarbon receptor cross-talks with multiple signal transduction pathways.

  2009cited by this paper
• The miR-124-Sox9 paramutation: RNA-mediated epigenetic control of embryonic and adult growth

  2009cited by this paper
• Reproductive Lesions in Female Harlan Sprague-Dawley Rats Following Two-Year Oral Treatment with Dioxin and Dioxin-like Compounds

  2009cited by this paper
• What is an epigenetic transgenerational phenotype? F3 or F2.

  2008cited by this paper
• Animal models for probing the developmental basis of disease and dysfunction paradigm.

  2008cited by this paper
• Hsp90 Affecting Chromatin Remodeling Might Explain Transgenerational Epigenetic Inheritance in Drosophila

  2008cited by this paper
• The aryl hydrocarbon receptor complex and the control of gene expression.

  2008cited by this paper
• RNA induction and inheritance of epigenetic cardiac hypertrophy in the mouse.

  2008cited by this paper
• Aryl Hydrocarbon Receptor-Mediated Down-Regulation of Sox9b Causes Jaw Malformation in Zebrafish Embryos

  2008cited by this paper
• Neonatal Thyroid Function in Seveso 25 Years after Maternal Exposure to Dioxin

  2008cited by this paper
• Dioxin Exposure, from Infancy through Puberty, Produces Endocrine Disruption and Affects Human Semen Quality

  2007cited by this paper
• Transgenerational epigenetic imprints on mate preference

  2007cited by this paper
• Role of exposure to environmental chemicals in the developmental basis of disease and dysfunction.

  2007cited by this paper
• Environmental toxicants and effects on female reproductive function.

  2006cited by this paper
• Inhibition of follicular development, vitellogenesis, and serum 17beta-estradiol concentrations in zebrafish following chronic, sublethal dietary exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin.

  2006cited by this paper
• A naturally occurring epigenetic mutation in a gene encoding an SBP-box transcription factor inhibits tomato fruit ripening

  2006cited by this paper
• Adverse Health Effects in Humans Exposed to 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD)

  2006cited by this paper
• Maternal Genistein Alters Coat Color and Protects Avy Mouse Offspring from Obesity by Modifying the Fetal Epigenome

  2006cited by this paper
• Epigenetic Transgenerational Actions of Endocrine Disruptors and Male Fertility

  2005cited by this paper
• Accumulation, tissue distribution, and maternal transfer of dietary 2,3,7,8,-tetrachlorodibenzo-p-dioxin: impacts on reproductive success of zebrafish.

  2005cited by this paper
• Serum dioxin concentrations and quality of ovarian function in women of Seveso.

  2005cited by this paper
• Repeated in utero and lactational 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure affects male gonads in offspring, leading to sex ratio changes in F2 progeny.

  2005cited by this paper
• The fetal basis of adult disease: Role of environmental exposures--introduction.

  2005cited by this paper
• In utero and lactational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin in rats disrupts brain sexual differentiation.

  2005cited by this paper
• Relationship of serum TCDD concentrations and age at exposure of female residents of Seveso, Italy.

  2004cited by this paper
• Developmental Origins of Disease Paradigm: A Mechanistic and Evolutionary Perspective

  2004cited by this paper
• Embryonic and fetal programming of physiological disorders in adulthood.

  2004cited by this paper
• Transgenerational transmission of radiation- and chemically induced tumors and congenital anomalies in mice: studies of their possible relationship to induced chromosomal and molecular changes

  2004cited by this paper
• How can chemical compounds alter human fertility?

  2002cited by this paper
• Semen quality after prenatal exposure to polychlorinated biphenyls and dibenzofurans.

  2000cited by this paper
• Paternal concentrations of dioxin and sex ratio of offspring.

  2000cited by this paper
• Where the boys aren't: dioxin and the sex ratio.

  2000cited by this paper
• Seveso Women's Health Study: a study of the effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on reproductive health.

  2000cited by this paper
• An epigenetic mutation responsible for natural variation in floral symmetry

  1999cited by this paper
• 2,3,7,8-Tetrachlorodibenzo-p-dioxin alters cardiovascular and craniofacial development and function in sac fry of rainbow trout (Oncorhynchus mykiss).

  1999cited by this paper
• Gestational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) severely alters reproductive function of female hamster offspring.

  1999cited by this paper
• Ah receptor agonists as endocrine disruptors: antiestrogenic activity and mechanisms.

  1998cited by this paper
• Ah receptor signaling pathways.

  1996cited by this paper
• Effects of 2,3,7,8‐tetrachlorodibenzo‐p‐dioxin, 12‐O‐tetradecanoylphorbol‐13‐acetate and 17β‐estradiol on estrogen receptor regulation in MCF‐7 human breast cancer cells

  1996cited by this paper
• Moving up the hierarchy: a hypothesis on the evolution of a genetic sex determination pathway.

  1995cited by this paper
• Toxicology of Dioxins and Related Chemicals

  1994cited by this paper
• Interactive regulation of Ah and glucocorticoid receptors in the synergistic induction of cleft palate by 2,3,7,8-tetrachlorodibenzo-p-dioxin and hydrocortisone.

  1994cited by this paper
• Developmental and reproductive toxicity of dioxins and related compounds: cross-species comparisons.

  1993cited by this paper
• The AH-receptor: genetics, structure and function.

  1993cited by this paper
• A brief review of the Ah locus.

  1992cited by this paper
• In utero and lactational exposure of male rats to 2,3,7,8-tetrachlorodibenzo-p-dioxin. 3. Effects on spermatogenesis and reproductive capability.

  1992cited by this paper
• In utero and lactational exposure of male rats to 2,3,7,8-tetrachlorodibenzo-p-dioxin. 2. Effects on sexual behavior and the regulation of luteinizing hormone secretion in adulthood.

  1992cited by this paper
• An estimate of the maximum in vivo covalent binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin to rat liver protein, ribosomal RNA, and DNA.

  1979cited by this paper

• Toxicological implications of polychlorinated dibenzo-p-dioxins (PCDDs) and dibenzofurans (PCDFs) in human and environmental matrices in developing countries

  2025cites this paper
• Potassium bromate toxicity and its mitigation: a mechanistic review with a transgenerational and systems toxicology outlook

  2025cites this paper
• The aryl hydrocarbon receptor: a new frontier in male reproductive system

  2025cites this paper
• Multi- and Transgenerational Histological and Transcriptomic Outcomes of Developmental TCDD Exposure in Zebrafish (Danio rerio) Ovary

  2025cites this paper
• Single generation epigenetic change in captivity and reinforcement in subsequent generations in a delta smelt (Hypomesus transpacificus) conservation hatchery

  2024cites this paper
• Impact of dioxins on reproductive health in female mammals

  2024cites this paper
• The uses of zebrafish (Danio rerio) as an in vivo model for toxicological studies: A review based on bibliometrics.

  2024cites this paper
• Embryonal exposure to 4-methylbenzylidene camphor induces reproduction impairment in adult zebrafish (Danio rerio).

  2024cites this paper
• A Quantitative Adverse Outcome Pathway for Embryonic Activation of the Aryl Hydrocarbon Receptor of Fishes by Polycyclic Aromatic Hydrocarbons Leading to Decreased Fecundity at Adulthood

  2024cites this paper
• Generational stability of epigenetic transgenerational inheritance facilitates adaptation and evolution

  2024cites this paper
• Benzo[a]pyrene-induced multigenerational changes in gene expression, behavior, and DNA methylation are primarily influenced by paternal exposure.

  2023cites this paper
• Differential Expression Profiles and Potential Intergenerational Functions of tRNA-Derived Small RNAs in Mice After Cadmium Exposure

  2022cites this paper
• Epigenetic Transgenerational Modifications Induced by Xenobiotic Exposure in Zebrafish

  2022cites this paper
• Insight into 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced disruption of zebrafish spermatogenesis via single cell RNA-seq

  2022cites this paper
• Multi- and Transgenerational Effects of Developmental Exposure to Environmental Levels of PFAS and PFAS Mixture in Zebrafish (Danio rerio)

  2022cites this paper
• The insecticide permethrin induces transgenerational behavioral changes linked to transcriptomic and epigenetic alterations in zebrafish (Danio rerio).

  2021cites this paper
• Exposure to a mixture of benzo[a]pyrene and triclosan induces multi-and transgenerational metabolic disorders associated with decreased female investment in reproduction in Silurana (Xenopus) tropicalis.

  2021cites this paper
• Use of zebrafish (Danio rerio) as a model for research in toxicological studies

  2021cites this paper
• Parental exposure to sulfamethazine and nanoplastics alters the gut microbial communities in the offspring of marine madaka (Oryzias melastigma).

  2021cites this paper
• Methylmercury induces transgenerationally transmissible epigenetic changes influencing zebrafish behavior

  2020cites this paper
• Transgenerational metabolic disorders and reproduction defects induced by benzo[a]pyrene in Xenopus tropicalis.

  2020cites this paper
• Testing for thyroid hormone disruptors, a review of non-mammalian in vivo models.

  2020cites this paper
• A Review of the Functional Roles of the Zebrafish Aryl Hydrocarbon Receptors.

  2020cites this paper
• Environmental Endocrine-Disrupting Chemical Exposure: Role in Non-Communicable Diseases

  2020cites this paper
• Changes in DNA Methylation Induced by Dioxins and Dioxin-Like Compounds as Potential Predictor of Disease Risk

  2020cites this paper
• TCDD-induced multi- and transgenerational changes in the methylome of male zebrafish gonads

  2020cites this paper
• Dioxins and dioxin-like compounds: toxicity in humans and animals, sources, and behaviour in the environment

  2019cites this paper
• Developmental Dioxin Exposure Alters the Methylome of Adult Male Zebrafish Gonads

  2019cites this paper
• Germline and Transgenerational Impacts of Toxicant Exposures

  2019cites this paper
• Atrazine induced transgenerational reproductive effects in medaka (Oryzias latipes).

  2019cites this paper
• A retrospective investigation into the occurrence and human exposure to polychlorinated naphthalenes (PCNs), dibenzo-p-dioxins and furans (PCDD/Fs) and PCBs through cod liver products (1972-2017).

  2019cites this paper
• Multigenerational and Transgenerational Effects of Dioxins

  2019cites this paper
• Transgenerational impairment of ovarian induced by 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) associated with Igf2 and H19 in adult female rat.

  2019cites this paper
• The dynamics of DNA methylation during epigenetic reprogramming of primordial germ cells in medaka (Oryzias latipes)

  2019cites this paper
• TRANSGENERATIONAL AND EPIGENETIC EFFECTS OF DEVELOPMENTAL EXPOSURE TO ATRAZINE ON MEDAKA ( ORYZIAS LATIPES ) by

  2018cites this paper
• Effects of low, subchronic exposure of 2,4‐Dichlorophenoxyacetic acid (2,4‐D) and commercial 2,4‐D formulations on early life stages of fathead minnows (Pimephales promelas)

  2018cites this paper
• Risk for animal and human health related to the presence of dioxins and dioxin‐like PCBs in feed and food

  2018cites this paper
• Bisphenol A in Eggs Impairs the Long-Term Stress Performance of Rainbow Trout in Two Generations.

  2018cites this paper
• Applying acoustic telemetry to understand contaminant exposure and bioaccumulation patterns in mobile fishes.

  2018cites this paper
• Biological Dogmas in Relation to the Origin of Evolutionary Novelties

  2018cites this paper
• Considering Epigenetics in Adverse Outcome Pathways

  2018cites this paper
• A rapid and reagent-free bioassay for the detection of dioxin-like compounds and other aryl hydrocarbon receptor (AhR) agonists using autobioluminescent yeast

  2018cites this paper
• Detection of Mitochondrial Toxicity Using Zebrafish

  2018cites this paper
• Ancestral TCDD Exposure Induces Multigenerational Histologic and Transcriptomic Alterations in Gonads of Male Zebrafish

  2018cites this paper
• In utero exposure to cigarette smoke and effects across generations: A conference of animals on asthma

  2018cites this paper
• Vinclozolin induced epigenetic transgenerational inheritance of pathologies and sperm epimutation biomarkers for specific diseases

  2018cites this paper
• Zebrafish in Toxicology and Environmental Health.

  2017cites this paper
• Aryl hydrocarbon receptor (AHR): "pioneer member" of the basic-helix/loop/helix per-Arnt-sim (bHLH/PAS) family of "sensors" of foreign and endogenous signals.

  2017cites this paper
• Early Life Exposure to Low Levels of AHR Agonist PCB126 (3,3′,4,4′,5-Pentachlorobiphenyl) Reprograms Gene Expression in Adult Brain

  2017cites this paper
• Epigenetics: Druggable targets for anti-cancer therapies

  2017cites this paper
• Mercury-induced epigenetic transgenerational inheritance of abnormal neurobehavior is correlated with sperm epimutations in zebrafish

  2017cites this paper
• Spermatogenesis disruption by dioxins: Epigenetic reprograming and windows of susceptibility.

  2017cites this paper
• Transgenerational inheritance of neurobehavioral and physiological deficits from developmental exposure to benzo[a]pyrene in zebrafish

  2017cites this paper
• Environmental epigenetics in zebrafish

  2017cites this paper
• Environmental factors, epigenetics, and developmental origin of reproductive disorders.

  2017cites this paper
• Chapter 21 – Transgenerational Epigenetic Inheritance: Past Exposures, Future Diseases

  2016cites this paper
• Embryonic Atrazine Exposure Elicits Alterations in Genes Associated with Neuroendocrine Function in Adult Male Zebrafish.

  2016cites this paper
• Environmentally Induced Epigenetic Transgenerational Inheritance of Reproductive Disease

  2015cites this paper
• Developmental exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin alters DNA methyltransferase (dnmt) expression in zebrafish (Danio rerio).

  2015cites this paper
• of contents for text on Dioxin and dioxin-like compounds currently on Wikipedia and for submitted (preprint) text, as well as reviewer comments

  year unknowncites this paper
• WikiJournal Preprints/Dioxins and dioxin-like compounds WikiJournal Preprints

  year unknowncites this paper