The impact of novel retinoids in combination with platinum chemotherapy on ovarian cancer stem cells.

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Gynecologic Oncology

• Publication date

  2012-04-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1016/j.ygyno.2011.12.425PMID 22155260PMCID PMC4049085
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2011influential reference
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  1993cited by this paper
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  1983cited by this paper

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