Role of the immune response in age-dependent resistance of mice to encephalitis due to Sindbis virus.

No abstract is available for this paper.

• Publication year

  1976

• Venue

  Journal of Infectious Diseases

• Publication date

  1976-04-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1093/INFDIS/133.4.456PMID 1262711
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Age Dependence of Viral Expression: Comparative Pathogenesis of Two Rodent-Adapted Strains of Measles Virus in Mice

  1974cited by this paper
• The role of the thymus in maturational development of phytohemagglutinin and pokeweed mitogen responsiveness.

  1973cited by this paper
• Viral infection and resistance in immunosuppressed host. 3. Intracerebral challenge with Sindbis virus in immunized or interferon inducer given mice.

  1973cited by this paper
• Age-dependent resistance of mice to sindbis virus infection: reticuloendothelial role.

  1973influential reference
• Age-dependent changes in sensitivity to antigen in the mouse.

  1973cited by this paper
• Predominance of theta-positive lymphocytes in gut-associated and peripheral lymphoid tissues of newborn mice.

  1973cited by this paper
• Cellular immune response to viral infection: in vitro studies of lymphocytes from mice infected with Sindbis virus.

  1973cited by this paper
• Age-dependent resistance of mice to sindbis virus infection: reticuloendothelial role.

  1973cited by this paper
• Lymphocyte classes in New Zealand mice. I. Ontogeny and mitogen responsiveness of thymocytes and thymus-derived lymphocytes.

  1972cited by this paper
• SPECIFICITY OF THE INFLAMMATORY RESPONSE IN VIRAL ENCEPHALITIS

  1972cited by this paper
• Age-dependent resistance to viral encephalitis: studies of infections due to Sindbis virus in mice.

  1972cited by this paper
• Functional heterogeneity of murine lymphoid cells. II. Acquisition of mitogen responsiveness and of theta antigen during the ontogeny of thymocytes and "T" lymphocytes.

  1972cited by this paper
• Immunocompetence of embryonic hemopoietic cells after traffic to thymus.

  1971cited by this paper
• Age-Dependent Resistance of Mice to Sindbis Virus Infection: Viral Replication as a Function of Host Age

  1971cited by this paper
• STUDIES ON THE DIFFERENTIATION OF THYMUS-DERIVED LYMPHOCYTES

  1970cited by this paper
• Pathogenesis of type 1 dengue virus infection in suckling, weanling and adult mice. 1. The relation of virus replication to interferon and antibody formation.

  1969cited by this paper
• ROLE OF MACROPHAGES IN IMMUNOLOGICAL MATURATION

  1968cited by this paper
• Beta-1C and immune globulin formation in vitro by tissues from germ-free and conventional rodents of various ages.

  1967cited by this paper
• ONTOGENY OF MACROPHAGE RESISTANCE TO MOUSE HEPATITIS IN VIVO AND IN VITRO

  1967cited by this paper
• Developmental aspects of immunity.

  1967cited by this paper
• Beta-1C and immune globulin formation in vitro by tissues from germ-free and conventional rodents of various ages.

  1967cited by this paper
• The Immunoglobulins of Mice. 4. Serum Immunoglobulin Changes Following Birth

  1965cited by this paper
• CELLULAR SUSCEPTIBILITY TO ENTEROVIRUSES.

  1964cited by this paper
• THE PATHOGENESIS OF HERPES VIRUS ENCEPHALITIS. II. A CELLULAR BASIS FOR THE DEVELOPMENT OF RESISTANCE WITH AGE.

  1964cited by this paper
• ASPECTS OF THE PATHOGENESIS OF VIRUS DISEASES.

  1964cited by this paper
• Thymus: Role in Maturation of Fetal Lymphoid Precursors

  1964cited by this paper
• PRODUCTION OF INTERFERON BY NEWBORN AND ADULT MICE INFECTED WITH SINDBIS VIRUS.

  1964cited by this paper
• THE PATHOGENESIS OF HERPES VIRUS ENCEPHALITIS

  1964cited by this paper
• THE IMMUNOGLOBULINS OF MICE

  1964cited by this paper
• Sindbis virus: a newly recognized arthropodtransmitted virus.

  1955cited by this paper
• Antibody response of suckling mice to mumps virus. I. Immune response following immunization with mumps virus vaccine.

  1954cited by this paper
• Antibody response of suckling mice to mumps virus. II. Relation of onset of antibody production to susceptibility to mumps virus infection.

  1954cited by this paper
• The interrelation of age. immune response, and susceptibility to mumps virus in hamsters.

  1953cited by this paper
• Influence of age on susceptibility to virus infections with particular reference to laboratory animals.

  1952cited by this paper
• Influence of Age on the Susceptibility of Mice to Infection with Certain Neurotropic Viruses

  1944cited by this paper
• INFLUENCE OF AGE ON SUSCEPTIBILITY AND ON IMMUNE RESPONSE OF MICE TO EASTERN EQUINE ENCEPHALOMYELITIS VIRUS

  1941cited by this paper
• Influence of Age on Rate of Immune Response of Mice to Formolized Equine Encephalomyelitis Virus

  1940cited by this paper

• Neuropathogenesis of Old World Alphaviruses: Considerations for the Development of Medical Countermeasures

  2025cites this paper
• The pathogenicity and virulence of Sindbis virus

  2025cites this paper
• Effect of Viral Strain and Host Age on Clinical Disease and Viral Replication in Immunocompetent Mouse Models of Chikungunya Encephalomyelitis

  2023influential citation
• Effect of IL-10 Deficiency on TGFβ Expression during Fatal Alphavirus Encephalomyelitis in C57Bl/6 Mice

  2022cites this paper
• The pediatric anti-viral immune response impairs neural stem/progenitor cell activity

  2020cites this paper
• A Rewarding Career Unraveling the Pathogenesis of Viral Infections.

  2020cites this paper
• Immunopathogenesis of alphaviruses.

  2020cites this paper
• Production of Noncapped Genomic RNAs Is Critical to Sindbis Virus Disease and Pathogenicity

  2020cites this paper
• Type II interferon signaling in the brain during a viral infection with age‐dependent pathogenesis

  2020influential citation
• Immunotherapeutic Challenges for Pediatric Cancers

  2019cites this paper
• NF-κB Activation Promotes Alphavirus Replication in Mature Neurons

  2019cites this paper
• Interferon regulatory factors 3 and 7 have distinct roles in the pathogenesis of alphavirus encephalomyelitis.

  2019cites this paper
• Interferon Control of Neurotropic Viral Infections.

  2019cites this paper
• Interleukin-10 Modulation of Virus Clearance and Disease in Mice with Alphaviral Encephalomyelitis

  2017cites this paper
• Age has a role in driving host immunopathological response to alphavirus infection

  2017cites this paper
• Alphavirus Encephalomyelitis: Mechanisms and Approaches to Prevention of Neuronal Damage

  2016cites this paper
• Animal Models

  2016cites this paper
• Short report Open Access

  2015cites this paper
• Arbovirus Replication and Increases 1 Expression of the Alpha Isoform of IRF-7 2 3

  2014cites this paper
• Cellular responses to Sindbis virus infection of neural progenitors derived from human embryonic stem cells

  2014cites this paper
• Virulence in Mice Interactions with Cell Surfaces and Encephalitis Virus E2 Glycoprotein Alters Binding Domain of the Eastern Equine Natural Variation in the Heparan Sulfate

  2014cites this paper
• Differentiation of Neurons Restricts Arbovirus Replication and Increases Expression of the Alpha Isoform of IRF-7

  2014cites this paper
• The role of innate versus adaptive immune responses in a mouse model of O'nyong-nyong virus infection.

  2013cites this paper
• Natural Variation in the Heparan Sulfate Binding Domain of the Eastern Equine Encephalitis Virus E2 Glycoprotein Alters Interactions with Cell Surfaces and Virulence in Mice

  2013influential citation
• Intrathecal Humoral Immunity to Encephalitic RNA Viruses

  2013cites this paper
• Mice Deficient in Interferon-Gamma or Interferon-Gamma Receptor 1 Have Distinct Inflammatory Responses to Acute Viral Encephalomyelitis

  2013cites this paper
• Activation of the Type I Interferon Pathway Is Enhanced in Response to Human Neuronal Differentiation

  2013cites this paper
• Effect of prophylactically applied CpG ODN on the development of myocarditis in mice infected with Coxsackievirus B3.

  2012cites this paper
• Recovery from viral encephalomyelitis: immune-mediated noncytolytic virus clearance from neurons

  2010cites this paper
• Interactions between neuronal innate immune pattern recognition receptor pathways and neurotropic arboviruses: Host measures, viral countermeasures, and potential therapeutics

  2010cites this paper
• Similarities and Differences in Antagonism of Neuron Alpha/Beta Interferon Responses by Venezuelan Equine Encephalitis and Sindbis Alphaviruses

  2009cites this paper
• Role of N-Linked Glycosylation for Sindbis Virus Infection and Replication in Vertebrate and Invertebrate Systems

  2009cites this paper
• The nsP3 macro domain is important for Sindbis virus replication in neurons and neurovirulence in mice

  2009cites this paper
• Host responses to alphavirus infection

  2008cites this paper
• Molecular pathogenesis of the Sindbis-group virus strain AR86

  2007influential citation
• Early restriction of alphavirus replication and dissemination contributes to age-dependent attenuation of systemic hyperinflammatory disease.

  2007influential citation
• Heparan Sulfate Binding Can Contribute to the Neurovirulence of Neuroadapted and Nonneuroadapted Sindbis Viruses

  2007cites this paper
• Non-pathogenic Sindbis virus causes hemorrhagic fever in the absence of alpha/beta and gamma interferons.

  2007cites this paper
• A mouse model of persistent brain infection with recombinant Measles virus.

  2006cites this paper
• Heparin-binding and patterns of virulence for two recombinant strains of Sindbis virus.

  2006cites this paper
• Early events in the pathogenesis of eastern equine encephalitis virus in mice.

  2005cites this paper
• Characterization of an In Vitro Model of Alphavirus Infection of Immature and Mature Neurons

  2005cites this paper
• Profile of Diane E. Griffin.

  2005cites this paper
• Identification of Adult Mouse Neurovirulence Determinants of the Sindbis Virus Strain AR86

  2005cites this paper
• Extensive immune-mediated hippocampal damage in mice surviving infection with neuroadapted Sindbis virus.

  2003cites this paper
• In vivo antitumor activity of Sindbis viral vectors.

  2002cites this paper
• Correlation of Susceptibility of Immature Mice to Fungal Infection (Blastomycosis) and Effector Cell Function

  2000cites this paper
• Alpha/Beta Interferon Protects Adult Mice from Fatal Sindbis Virus Infection and Is an Important Determinant of Cell and Tissue Tropism

  2000cites this paper
• Control of Sindbis Virus Infection by Antibody in Interferon-Deficient Mice

  2000cites this paper
• Differences between C57BL/6 and BALB/cBy Mice in Mortality and Virus Replication after Intranasal Infection with Neuroadapted Sindbis Virus

  2000cites this paper
• The Role of CD8+ T Cells and Major Histocompatibility Complex Class I Expression in the Central Nervous System of Mice Infected with Neurovirulent Sindbis Virus

  2000cites this paper
• TNFα, Interferon, and Stress Response Induction as a Function of Age-Related Susceptibility to Fatal Sindbis Virus Infection of Mice

  1999cites this paper
• TNFalpha, interferon, and stress response induction as a function of age-related susceptibility to fatal Sindbis virus infection of mice.

  1999cites this paper
• Age-dependent susceptibility in mumps-associated hydrocephalus: neuropathologic features and brain barriers

  1997cites this paper
• Susceptibility to a neurotropic virus and its changing distribution in the developing brain is a function of CNS maturity.

  1997cites this paper
• Regulators of apoptosis on the road to persistent alphavirus infection.

  1997cites this paper
• The role of antibody in recovery from alphavirus encephalitis

  1997cites this paper
• The Gordon Wilson lecture: unique interactions between viruses, neurons and the immune system.

  1996cites this paper
• Age-dependent susceptibility to fatal encephalitis: alphavirus infection of neurons.

  1994cites this paper
• Viral determinants of age-dependent virulence of Sindbis virus for mice

  1993cites this paper
• Antibody-mediated clearance of alphavirus infection from neurons.

  1991cites this paper
• Pathogenesis of encephalitis induced in newborn mice by virulent and avirulent strains of Sindbis virus

  1990cites this paper
• Characterization of the local and systemic B cell response of normal and athymic nude mice with Sindbis virus encephalitis.

  1989cites this paper
• Role of the immune response in Sindbis virus-induced paralysis of SJL/J mice.

  1989cites this paper
• Viral Infections and the Blood-Brain Barrier

  1989cites this paper
• Molecular basis of Sindbis virus neurovirulence in mice

  1988cites this paper
• Immune Responses in the Central Nervous System

  1987cites this paper
• Identification of the Inflammatory Cells in the Central Nervous System during Acute Viral Encephalitis

  1987cites this paper
• The pathogenesis of spinal cord involvement in the encephalomyelitis of mice caused by neuroadapted Sindbis virus infection.

  1987cites this paper
• Alphavirus Pathogenesis and Immunity

  1986cites this paper
• Alphavirus neurovirulence: monoclonal antibodies discriminating wild-type from neuroadapted Sindbis virus

  1985cites this paper
• Immune responses to acute alphavirus infection of the central nervous system: Sindbis virus encephalitis in mice.

  1983cites this paper
• Production of mononuclear cell chemotactic factors during Sindbis virus infection of mice

  1982cites this paper
• Immunology of Rabies, Arbovirus Encephalitis, Parainfectious Encephalitis, and Guillain-Barré Syndrome

  1982cites this paper
• Maturity as a critical determinant of resistance to fungal infections: studies in murine blastomycosis

  1982cites this paper
• Immunoglobulins in the cerebrospinal fluid: changes during acute viral encephalitis in mice.

  1981cites this paper
• Development of age-dependent resistance to sindbis virus encephalitis: correlation with inactivation of virus within the blood stream.

  1981cites this paper
• Experimental viral polymyositis

  1981cites this paper
• Natural killer cells appear to play no role in the recovery of mice from Sindbis virus infection.

  1981cites this paper
• 4 – Virus–Host Interactions in Natural and Experimental Infections with Alphaviruses and Flaviviruses

  1980cites this paper
• The role of complement in viral infections. III. Activation of the classical and alternative complement pathways by Sindbis virus.

  1980cites this paper
• Pathogenesis of Human Poliovirus Infection in Mice: II. Age‐Dependency of Paralysis

  1980cites this paper
• [Effect of cyclophosphamide and antithymocyte serum on the resistance of the adult rat to Junin virus].

  1980cites this paper
• Role of complement in viral infections: participation of terminal complement components (C5 to C9) in recovery of mice from Sindbis virus infection

  1980cites this paper
• The role of complement in viral infections. II. the clearance of Sindbis virus from the bloodstream and central nervous system of mice depleted of complement.

  1980cites this paper
• Pathogenesis of Human Poliovirus Infection in Mice: I. Clinical and Pathological Studies

  1980cites this paper
• Interactions between immune cells and antibody in protection from fatal Sindbis virus encephalitis

  1979cites this paper
• The pathogenesis of Sindbis virus infection in athymic nude mice.

  1979cites this paper
• PERSISTENT INFECTIONS WITH »RUNDE« VIRUS IN CELL CULTURES AND SUCKLING MICE

  1978cites this paper
• Resistance to fatal central nervous system disease by mouse hepatitis virus, strain JHM

  1978cites this paper
• The effect of complement depletion on the course of Sindbis virus infection in mice.

  1978cites this paper
• An electron-microscopic study of avirulent and virulent Semliki forest virus in the brains of different ages of mice.

  1978cites this paper
• Role of the immune response in recovery from Sindbis virus encephalitis in mice.

  1977cites this paper
• Age-dependent and strain-related differences of virulence of Semliki Forest virus in mice.

  1977cites this paper