Roles for Drp1, a Dynamin-related Protein, and Milton, a Kinesin-associated Protein, in Mitochondrial Segregation, Unfurling, and Elongation During Drosophila Spermatogenesis

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Fly

• Publication date

  2007-01-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.4161/fly.3913PMID 18690063
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The Drosophila parkin homologue is required for normal mitochondrial dynamics during spermiogenesis.

  2007cited by this paper
• Milton controls the early acquisition of mitochondria by Drosophila oocytes

  2006cited by this paper
• Axonal transport of mitochondria requires milton to recruit kinesin heavy chain and is light chain independent

  2006cited by this paper
• Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin

  2006cited by this paper
• Mitochondrial morphology and dynamics in yeast and multicellular eukaryotes.

  2005cited by this paper
• Synaptic mitochondria are critical for mobilization of reserve pool vesicles at Drosophila neuromuscular junctions.

  2005cited by this paper
• Dynein anchors its mRNA cargo after apical transport in the Drosophila blastoderm embryo.

  2005cited by this paper
• The GTPase dMiro is required for axonal transport of mitochondria to Drosophila synapses.

  2005cited by this paper
• Dnm1 forms spirals that are structurally tailored to fit mitochondria

  2005cited by this paper
• Importance of mitochondrial dynamics during meiosis and sporulation.

  2004cited by this paper
• The BDGP Gene Disruption Project

  2004cited by this paper
• Alternative topogenesis of Mgm1 and mitochondrial morphology depend on ATP and a functional import motor

  2004cited by this paper
• FlyBase: genes and gene models

  2004cited by this paper
• The machinery of mitochondrial fusion, division, and distribution, and emerging connections to apoptosis.

  2004cited by this paper
• Processing of Mgm1 by the Rhomboid-type Protease Pcp1 Is Required for Maintenance of Mitochondrial Morphology and of Mitochondrial DNA*

  2003cited by this paper
• The Arabidopsis Dynamin-Like Proteins ADL1C and ADL1E Play a Critical Role in Mitochondrial Morphogenesis Article, publication date, and citation information can be found at www.plantcell.org/cgi/doi/10.1105/tpc.015222.

  2003cited by this paper
• Mitochondrial membrane remodelling regulated by a conserved rhomboid protease

  2003cited by this paper
• Mitochondrial positioning in fission yeast is driven by association with dynamic microtubules and mitotic spindle poles

  2003cited by this paper
• Cells lacking Pcp1p/Ugo2p, a rhomboid-like protease required for Mgm1p processing, lose mtDNA and mitochondrial structure in a Dnm1p-dependent manner, but remain competent for mitochondrial fusion.

  2003cited by this paper
• Mitochondria are redistributed in Drosophila photoreceptors lacking Milton, a kinesin‐associated protein

  2003cited by this paper
• A Balbiani body and the fusome mediate mitochondrial inheritance during Drosophila oogenesis

  2003cited by this paper
• Axonal transport of mitochondria to synapses depends on milton, a novel Drosophila protein.

  2002cited by this paper
• A dynamin-like protein (ADL2b), rather than FtsZ, is involved in Arabidopsis mitochondrial division

  2002cited by this paper
• Dynamin-related protein Drp1 is required for mitochondrial division in mammalian cells.

  2001cited by this paper
• Arp2/3 complex and actin dynamics are required for actin-based mitochondrial motility in yeast

  2001cited by this paper
• A phospholipid kinase regulates actin organization and intercellular bridge formation during germline cytokinesis.

  2000cited by this paper
• Gene discovery using computational and microarray analysis of transcription in the Drosophila melanogaster testis.

  2000cited by this paper
• Division versus Fusion: Dnm1p and Fzo1p Antagonistically Regulate Mitochondrial Shape

  1999cited by this paper
• Cytoplasmic dynein, the dynactin complex, and kinesin are interdependent and essential for fast axonal transport.

  1999cited by this paper
• The dynamin-related GTPase Dnm1 regulates mitochondrial fission in yeast

  1999cited by this paper
• C. elegans dynamin-related protein DRP-1 controls severing of the mitochondrial outer membrane.

  1999cited by this paper
• Targeted disruption of mouse conventional kinesin heavy chain, kif5B, results in abnormal perinuclear clustering of mitochondria.

  1998cited by this paper
• The Cellular and Subcellular Localization of Huntingtin-Associated Protein 1 (HAP1): Comparison with Huntingtin in Rat and Human

  1998cited by this paper
• The Dynamin-related GTPase, Dnm1p, Controls Mitochondrial Morphology in Yeast

  1998cited by this paper
• Kinesin Light Chains Are Essential for Axonal Transport in Drosophila

  1998cited by this paper
• A Human Dynamin-related Protein Controls the Distribution of Mitochondria

  1998cited by this paper
• Developmentally regulated mitochondrial fusion mediated by a conserved, novel, predicted GTPase.

  1997cited by this paper
• Fast transport and retrograde movement of huntingtin and HAP 1 in axons

  1997cited by this paper
• Mitochondrial Association of a Plus End–Directed Microtubule Motor Expressed during Mitosis in Drosophila

  1997cited by this paper
• Kinesin mutations cause motor neuron disease phenotypes by disrupting fast axonal transport in Drosophila.

  1996cited by this paper
• Local transposition of P elements in Drosophila melanogaster and recombination between duplicated elements using a site-specific recombinase.

  1994cited by this paper
• Site-specific recombination between homologous chromosomes in Drosophila.

  1991cited by this paper
• Two Drosophila beta tubulin isoforms are not functionally equivalent

  1990cited by this paper
• The FLP recombinase of yeast catalyzes site-specific recombination in the Drosophila genome.

  1989cited by this paper
• The testis-specific β-tubulin subunit in Drosophila melanogaster has multiple functions in spermatogenesis

  1982cited by this paper
• Cytodifferentiation during spermatogenesis in Drosophila melanogaster : an electron microscope study

  1971cited by this paper
• INSECT SPERM: THEIR STRUCTURE AND MORPHOGENESIS

  1970cited by this paper
• Development in DROSOPHILA MELANOGASTER.

  1927cited by this paper

• Developmental coordination of mitochondrial dynamics and membrane remodeling drives organelle morphogenesis

  2025cites this paper
• A comparison of spermatogenesis between flies and men—conserved processes of male gamete production

  2025influential citation
• Marf- and Opa1-Dependent Formation of Mitochondrial Network Structure Is Required for Cell Growth and Subsequent Meiosis in Drosophila Males

  2025cites this paper
• Cytoplasmic incompatibility factor proteins from Wolbachia prophage are costly to sperm development in Drosophila melanogaster

  2025cites this paper
• Mitochondrial Differentiation during Spermatogenesis: Lessons from Drosophila melanogaster

  2024influential citation
• Peroxisome inter-organelle cooperation in Drosophila.

  2024cites this paper
• Mitochondrial morphology dynamics and ROS regulate apical polarity and differentiation in Drosophila follicle cells.

  2024cites this paper
• Mitochondrial morphology dynamics and ROS regulate apical polarity and differentiation in Drosophila follicle cells

  2023cites this paper
• Milton assembles large mitochondrial clusters, mitoballs, to sustain spermatogenesis

  2023cites this paper
• Mitochondrial Neurodegeneration: Lessons from Drosophila melanogaster Models

  2023cites this paper
• Structure and molecular basis of spermatid elongation in the Drosophila testis

  2023cites this paper
• Dynamin-like Protein 1 (DNML1) as a Molecular Target for Antibody-Based Immunotherapy to Treat Glaucoma

  2022cites this paper
• Mitochondrial Features and Expressions of MFN2 and DRP1 during Spermiogenesis in Phascolosoma esculenta

  2022cites this paper
• Mitochondrial fusion regulates proliferation and differentiation in the type II neuroblast lineage in Drosophila

  2021cites this paper
• Hydrogen-rich medium ameliorates lipopolysaccharides-induced mitochondrial fission and dysfunction in human umbilical vein endothelial cells (HUVECs) via up-regulating HO-1 expression.

  2021cites this paper
• Motor proteins at the mitochondria–cytoskeleton interface

  2021cites this paper
• DRP1 deficiency induces mitochondrial dysfunction and oxidative stress-mediated apoptosis during porcine oocyte maturation

  2020cites this paper
• Mitochondrial Miro GTPases coordinate mitochondrial and peroxisomal dynamics

  2020cites this paper
• Mitochondrial Segregation in Budding Yeast Gametogenesis

  2019cites this paper
• A Molecular Perspective on Mitochondrial Membrane Fusion: From the Key Players to Oligomerization and Tethering of Mitofusin

  2019cites this paper
• Male-biased retrogenes in Drosophila melanogaster: integration of novel genes into pathways governing sperm development

  2017cites this paper
• Mitochondrial fusion/fission dynamics in neurodegeneration and neuronal plasticity.

  2016cites this paper
• Mitochondrial Biology in Hepatobiliary Tumors: Changes of the Cellular Energy Factory

  2016cites this paper
• Testis-Specific Bb8 Is Essential in the Development of Spermatid Mitochondria

  2016cites this paper
• Germ‐cell hub position in a heteropteran testis correlates with the sequence and location of spermatogenesis and production of elaborate sperm bundles

  2015cites this paper
• Dynamin-1-like protein (Dnm1L) interaction with kinesin light chain 1 (KLC1) through the tetratricopeptide repeat (TPR) domains

  2014cites this paper
• Spermitin: A Novel Mitochondrial Protein in Drosophila Spermatids

  2014cites this paper
• D. melanogaster, mitochondria and neurodegeneration: small model organism, big discoveries.

  2013cites this paper
• Acroframosome-Dependent KIFC1 Facilitates Acrosome Formation during Spermatogenesis in the Caridean Shrimp Exopalaemon modestus

  2013cites this paper
• Drosophila spermiogenesis

  2012influential citation
• Drosophila male-sterile mutation emmenthal specifically affects the mitochondrial morphogenesis

  2012cites this paper
• Scanning Electron Microscopy for the Life Sciences: Mitochondrial continuous intracellular network-structures visualized with high-resolution field-emission scanning electron microscopy

  2012cites this paper
• Drosophila tumor suppressor merlin is essential for mitochondria morphogenesis during spermatogenesis in Drosophila melanogaster

  2011cites this paper
• Genome-wide screen for modifiers of Parkinson's disease genes in Drosophila

  2011cites this paper
• Sustained elongation of sperm tail promoted by local remodeling of giant mitochondria in Drosophila.

  2011cites this paper
• Mitochondrial dynamics in model organisms: what yeasts, worms and flies have taught us about fusion and fission of mitochondria.

  2010cites this paper
• A Novel Predicted Bromodomain-Related Protein Affects Coordination Between Meiosis and Spermiogenesis in Drosophila and Is Required for Male Meiotic Cytokinesis

  2010cites this paper
• Ca2+-dependent regulation of mitochondrial dynamics by the Miro-Milton complex.

  2009cites this paper
• The molecular mechanism and cellular functions of mitochondrial division.

  2009cites this paper
• A Novel Potential Role for Gametogenetin-Binding Protein 1 (GGNBP1) in Mitochondrial Morphogenesis During Spermatogenesis in Mice1

  2009cites this paper
• HUMMR, a hypoxia- and HIF-1α–inducible protein, alters mitochondrial distribution and transport

  2009cites this paper
• Moving Mitochondria: Establishing Distribution of an Essential Organelle

  2007cites this paper
• Jcb: Article

  year unknowncites this paper