Skin-infiltrating monocytes/macrophages migrate to draining lymph nodes and produce IL-10 after contact sensitizer exposure to UV-irradiated skin.

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Journal of Investigative Dermatology

• Publication date

  2008-11-01

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1038/jid.2008.137PMID 18509360PMCID PMC3910256
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Monocyte-Derived Human Macrophages Mediate Anergy in Allogeneic T Cells and Induce Regulatory T Cells1

  2006cited by this paper
• Prevention of UV radiation–induced immunosuppression by IL-12 is dependent on DNA repair

  2005cited by this paper
• The macrophage F4/80 receptor is required for the induction of antigen-specific efferent regulatory T cells in peripheral tolerance

  2005cited by this paper
• Ultraviolet Radiation-Induced Regulatory T Cells Not Only Inhibit the Induction but Can Suppress the Effector Phase of Contact Hypersensitivity1

  2004cited by this paper
• Differentiation of T Regulatory Cells by Immature Dendritic Cells

  2001cited by this paper
• Dose Response for UV-induced Immune Suppression in People of Color: Differences Based on Erythemal Reactivity Rather than Skin Pigmentation¶

  2001cited by this paper
• Exposure to Ultraviolet Radiation Causes Dendritic Cells/Macrophages to Secrete Immune-Suppressive IL-12p40 Homodimers1

  2000cited by this paper
• Evidence for Functional Relevance of CTLA-4 in Ultraviolet-Radiation-Induced Tolerance1

  2000cited by this paper
• In human skin, UVB initiates early induction of IL-10 over IL-12 preferentially in the expanding dermal monocytic/macrophagic population.

  1998cited by this paper
• Origin and characteristics of ultraviolet-B radiation-induced suppressor T lymphocytes.

  1998influential reference
• Endogenous monocyte chemoattractant protein‐1 recruits monocytes in the zymosan peritonitis model

  1998cited by this paper
• Hapten-specific tolerance induced by acute, low-dose ultraviolet B radiation of skin is mediated via interleukin-10.

  1997cited by this paper
• Evidence that DNA damage triggers interleukin 10 cytokine production in UV-irradiated murine keratinocytes.

  1996cited by this paper
• Neutralization of IL-12 in vivo prevents induction of contact hypersensitivity and induces hapten-specific tolerance.

  1996cited by this paper
• Temporal correlation between UV radiation locally-inducible tolerance and the sequential appearance of dermal, then epidermal, class II MHC+CD11b+ monocytic/macrophagic cells.

  1996cited by this paper
• IL-12 synthesis by human Langerhans cells.

  1996cited by this paper
• High level IL-12 production by murine dendritic cells: upregulation via MHC class II and CD40 molecules and downregulation by IL-4 and IL-10 [published erratum appears in J Exp Med 1996 Oct 1;184(4):following 1590]

  1996cited by this paper
• Reversal of immunosuppression inducible through ultraviolet-exposed skin by in vivo anti-CD11b treatment.

  1996cited by this paper
• Interleukin-12 prevents ultraviolet B-induced local immunosuppression and overcomes UVB-induced tolerance.

  1996cited by this paper
• Effect of IL-12 on immune suppression and suppressor cell induction by ultraviolet radiation.

  1995cited by this paper
• In human dermis, ultraviolet radiation induces expansion of a CD36+ CD11b+ CD1- macrophage subset by infiltration and proliferation; CD1+ Langerhans-like dendritic antigen-presenting cells are concomitantly depleted.

  1995cited by this paper
• Induction of IL-10 gene expression in human keratinocytes by UVB exposure in vivo and in vitro.

  1995cited by this paper
• IL-12 as mediator and adjuvant for the induction of contact sensitivity in vivo.

  1995influential reference
• Active induction of unresponsiveness (tolerance) to DNFB by in vivo ultraviolet-exposed epidermal cells is dependent upon infiltrating class II MHC+ CD11bbright monocytic/macrophagic cells.

  1994cited by this paper
• CD11b+ macrophages that infiltrate human epidermis after in vivo ultraviolet exposure potently produce IL-10 and represent the major secretory source of epidermal IL-10 protein.

  1994cited by this paper
• Induction of hapten-specific tolerance by interleukin 10 in vivo

  1994cited by this paper
• Inhibition of Langerhans cell antigen-presenting function by IL-10. A role for IL-10 in induction of tolerance.

  1993cited by this paper
• Neutrophils, differentiated macrophages, and monocyte/macrophage antigen presenting cells infiltrate murine epidermis after UV injury.

  1993cited by this paper
• Antigen markers of macrophage differentiation in murine tissues.

  1992cited by this paper
• Production of natural killer cell stimulatory factor (interleukin 12) by peripheral blood mononuclear cells

  1992cited by this paper
• The effect of ultraviolet B irradiation and urocanic acid isomers on dendritic cell migration.

  1992cited by this paper
• UV exposure reduces immunization rates and promotes tolerance to epicutaneous antigens in humans: relationship to dose, CD1a-DR+ epidermal macrophage induction, and Langerhans cell depletion.

  1992cited by this paper
• Evidence that cutaneous antigen-presenting cells migrate to regional lymph nodes during contact sensitization.

  1990cited by this paper
• UVB and UVC, but not UVA, potently induce the appearance of T6- DR+ antigen-presenting cells in human epidermis.

  1987cited by this paper
• Analysis of the mechanism of unresponsiveness produced by haptens painted on skin exposed to low dose ultraviolet radiation

  1983cited by this paper
• F4/80, a monoclonal antibody directed specifically against the mouse macrophage

  1981cited by this paper
• Epidermal Langerhans cell density determines whether contact hypersensitivity or unresponsiveness follows skin painting with DNFB.

  1980cited by this paper

• UVA1 exposures change gene expression and circadian time-related protein CRY2 in human skin.

  2026cites this paper
• Crosslinking of Ly6a metabolically reprograms CD8 T cells for cancer immunotherapy

  2024cites this paper
• Highly bioactive triple-helical nano collagens for accelerated treatment of photodamaged skin.

  2024cites this paper
• Evaluation of the association of chronic inflammation and cancer: Insights and implications.

  2023cites this paper
• Monocytes and Macrophages in the Cancer Immunity Cycle

  2022cites this paper
• Non-denatured yak type I collagen accelerates sunburned skin healing by stimulating and replenishing dermal collagen

  2022cites this paper
• Topical application of the antimicrobial agent triclosan induces NLRP3 inflammasome activation and mitochondrial dysfunction.

  2020cites this paper
• Vitamin D improves sunburns by increasing autophagy in M2 macrophages

  2019cites this paper
• Immune checkpoint molecules: “new” kids on the block of skin photoimmunology

  2019cites this paper
• Low-dose ionizing radiation exposure represses the cell cycle and protein synthesis pathways in in vitro human primary keratinocytes and U937 cell lines

  2018cites this paper
• Effect of phototherapy on B and T lymphocytes in Egyptian infants suffering from neonatal jaundice.

  2017cites this paper
• In vivo quantification of quantum dot systemic transport in C57BL/6 hairless mice following skin application post-ultraviolet radiation

  2017cites this paper
• Understanding the connection between platelet-activating factor, a UV-induced lipid mediator of inflammation, immune suppression and skin cancer.

  2016influential citation
• B cells are required for sunlight protection of mice from a CNS-targeted autoimmune attack.

  2016cites this paper
• The HPV16 E7 Oncoprotein Disrupts Dendritic Cell Function and Induces the Systemic Expansion of CD11b+Gr1+ Cells in a Transgenic Mouse Model

  2016cites this paper
• Identification of skin immune cells in non-human primates.

  2015cites this paper
• Non-melanoma skin cancer, sun exposure and sun protection.

  2015cites this paper
• Nutritional abrogation of photoimmunosuppression: in vivo investigations

  2014cites this paper
• Pharmacologically antagonizing the CXCR4-CXCL12 chemokine pathway with AMD3100 inhibits sunlight-induced skin cancer.

  2014cites this paper
• Photoimmunology.

  2014cites this paper
• Photoimmunosuppression: a brief overview

  2013cites this paper
• Gene profiling of narrowband UVB-induced skin injury defines cellular and molecular innate immune responses.

  2013cites this paper
• Phototherapeutic hardening modulates systemic cytokine levels in patients with polymorphic light eruption

  2012cites this paper
• Fotoinmunología. Efectos inmunológicos de las radiaciones ultravioletas y sus implicaciones en dermatología

  2012cites this paper
• The suppressive effects of ultraviolet radiation on immunity in the skin and internal organs: implications for autoimmunity.

  2012cites this paper
• IL-10 controls dendritic cell-induced T-cell reactivation in the skin to limit contact hypersensitivity.

  2012cites this paper
• Photoprotection against the UVB‐induced oxidative stress and epidermal damage in mice using leaves of three different varieties of Lepidium meyenii (maca)

  2011cites this paper
• The Consequences of UV‐Induced Immunosuppression for Human Health

  2011cites this paper
• The Mechanisms and Consequences of Ultraviolet-Induced Immunosuppression in the Skin and Eye

  2011cites this paper
• UV immunosuppression and cutaneous malignancies

  2011cites this paper
• The challenges of UV-induced immunomodulation for children's health.

  2011cites this paper
• CXCL5 Mediates UVB Irradiation–Induced Pain

  2011cites this paper
• The Role of CD8 T Cells and Their Antigen Receptors in Psoriasis

  2010cites this paper
• Short-term stress enhances cellular immunity and increases early resistance to squamous cell carcinoma.

  2010cites this paper
• Prevention of scattered light‐induced asthenopia and fatigue by a polarized filter

  2010cites this paper
• Reversal of ultraviolet B‐induced immunosuppression by inhibition of the extracellular signal‐regulated mitogen‐activated protein kinase

  2009cites this paper
• The alternative complement pathway seems to be a UVA sensor that leads to systemic immunosuppression.

  2009cites this paper
• Fluorescent Imaging of Antigen Released by a Skin-Invading Helminth Reveals Differential Uptake and Activation Profiles by Antigen Presenting Cells

  2009cites this paper
• Photoaging in Skin of Color

  2009cites this paper
• The Photobiology of Human Skin

  2008cites this paper