Melatonin, Longevity and Health in the Aged: An Assessment

No abstract is available for this paper.

• Publication year

  2002

• Venue

  Free radical research

• Publication date

  2002-01-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1080/1071576021000038504PMID 12607824
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Melatonin in plants.

  2009cited by this paper
• Melatonin in plants

  2008cited by this paper
• Biochemical reactivity of melatonin with reactive oxygen and nitrogen species

  2007cited by this paper
• Melatonin Enters the Cerebrospinal Fluid through the Pineal Recess.

  2002cited by this paper
• Melatonin: reducing the toxicity and increasing the efficacy of drugs

  2002cited by this paper
• Melatonin as a chronobiotic/anticancer agent: cellular, biochemical, and molecular mechanisms of action and their implications for circadian-based cancer therapy.

  2002influential reference
• Melatonin as an effective protector against doxorubicin-induced cardiotoxicity.

  2002cited by this paper
• Melatonin reduces oxidative damage and increases survival of mice infected with Schistosoma mansoni.

  2002cited by this paper
• Extension of life span and stress resistance of Drosophila melanogaster by long-term supplementation with melatonin.

  2002influential reference
• Beneficial neurobiological effects of melatonin under conditions of increased oxidative stress

  2002cited by this paper
• Is there a role for melatonin in supportive care?

  2002cited by this paper
• Chemical and physical properties and potential mechanisms: melatonin as a broad spectrum antioxidant and free radical scavenger.

  2002cited by this paper
• Melatonin-immune system relationships.

  2002cited by this paper
• Effects of Melatonin, Vitamin E and Octreotide on Lipid Peroxidation during Ischemia-Reperfusion in the Guinea Pig Retina

  2002cited by this paper
• Effects of melatonin, vitamin E and octreotide on lipid peroxidation during ischemia- reperfusion in the guinea pig retina.

  2002cited by this paper
• Melatonin, mitochondrial homeostasis and mitochondrial-related diseases.

  2002cited by this paper
• Melatonin enters the cerebrospinal fluid through the pineal recess.

  2002cited by this paper
• Melatonin increases both life span and tumor incidence in female CBA mice.

  2001cited by this paper
• Acute ethanol administration oxidatively damages and depletes mitochondrial dna in mouse liver, brain, heart, and skeletal muscles: protective effects of antioxidants.

  2001cited by this paper
• Melatonin versus vitamin E as protective treatment against oxidative stress after extra‐hepatic bile duct ligation in rats

  2001cited by this paper
• N1‐acetyl‐N2‐formyl‐5‐methoxykynuramine, a biogenic amine and melatonin metabolite, functions as a potent antioxidant

  2001cited by this paper
• In vivo changes in antioxidant systems and protective role of melatonin and a combination of vitamin C and vitamin E on oxidative damage in erythrocytes induced by chlorpyrifos-ethyl in rats

  2001cited by this paper
• Melatonin, mitochondria, and cellular bioenergetics

  2001cited by this paper
• Individual and synergistic antioxidative actions of melatonin: studies with vitamin E, vitamin C, glutathione and desferrrioxamine (desferoxamine) in rat liver homogenates

  2001cited by this paper
• Role of Free Radicals in the Neurodegenerative Diseases

  2001cited by this paper
• Antioxidative Capacity of Melatonin

  2001cited by this paper
• Modulatory Effects of Melatonin and Vitamin E on Doxorubicin-Induced Cardiotoxicity in Ehrlich Ascites Carcinoma-Bearing Mice

  2000cited by this paper
• THE HUMAN CIRCADIAN CLOCK AND AGING

  2000cited by this paper
• Phosphine-induced oxidative damage in rats: attenuation by melatonin.

  2000cited by this paper
• Actions of Melatonin in the Reduction of Oxidative Stress

  2000cited by this paper
• Melatonin but not vitamins C and E maintains glutathione homeostasis in t‐butyl hydroperoxide‐induced mitochondrial oxidative stress

  2000cited by this paper
• Augmentation of indices of oxidative damage in life-long melatonin-deficient rats.

  1999cited by this paper
• Resveratrol, melatonin, vitamin E, and PBN protect against renal oxidative DNA damage induced by the kidney carcinogen KBrO3.

  1999cited by this paper
• High physiological levels of melatonin in the bile of mammals.

  1999cited by this paper
• Melatonin induces γ-glutamylcysteine synthetase mediated by activator protein-1 in human vascular endothelial cells

  1999cited by this paper
• Melatonin induces gamma-glutamylcysteine synthetase mediated by activator protein-1 in human vascular endothelial cells.

  1999cited by this paper
• Maternal‐fetal transfer of melatonin in pregnant women near term

  1998cited by this paper
• Oxidative damage in the central nervous system: protection by melatonin.

  1998cited by this paper
• New actions of melatonin and their relevance to biometeorology

  1997cited by this paper
• Supplemental melatonin increases clonal lifespan in the protozoan Paramecium tetraurelia

  1997influential reference
• Melatonin in the Context of the Free Radical Theory of Aging a

  1996cited by this paper
• Lithium chloride enhances survival of NZB/W lupus mice: influence of melatonin and timing of treatment.

  1995cited by this paper
• Modulation of aging processes by dietary restriction

  1994cited by this paper
• Detection and quantification of melatonin in a dinoflagellate, Gonyaulax polyedra: Solutions to the problem of methoxyindole destruction in non‐vertebrate material

  1994cited by this paper
• Pineal control of aging: effect of melatonin and pineal grafting on aging mice.

  1994cited by this paper
• Nuclear localization of melatonin in different mammalian tissues: Immunocytochemical and radioimmunoassay evidence

  1993cited by this paper
• The ageing pineal gland and its physiological consequences

  1992cited by this paper
• Free‐Radical Theory of Aging

  1992cited by this paper
• Pineal melatonin: cell biology of its synthesis and of its physiological interactions.

  1991cited by this paper
• Melatonin in human preovulatory follicular fluid.

  1987cited by this paper
• The pineal and its hormones in the control of reproduction in mammals.

  1980cited by this paper
• ISOLATION OF MELATONIN, THE PINEAL GLAND FACTOR THAT LIGHTENS MELANOCYTES1

  1958cited by this paper

• The potential role of mesenchymal stem cells enhanced with melatonin in renal damage induced experimentally by cecal ligation and puncture in rats.

  2026cites this paper
• Unveiling mysteries of aging: the potential of melatonin in preventing neurodegenerative diseases in older adults

  2025cites this paper
• Targeting the Multiple Complex Processes of Hypoxia-Ischemia to Achieve Neuroprotection

  2024cites this paper
• Nutritional Quality and Bioactive Constituents of Six Australian Plum Varieties

  2020cites this paper
• Melatonin for the treatment of sepsis: the scientific rationale.

  2020cites this paper
• Use of Melatonin in Oxidative Stress Related Neonatal Diseases

  2020cites this paper
• Redox homeostasis in a rodent model of circadian disruption: Effect of melatonin supplementation.

  2019cites this paper
• Melatonin and Its Antiaging Activity: New Approaches and Strategies for Age-Related Disorders

  2018cites this paper
• Receptor Cross Talk and Interplay between Melatonin and Ovarian Thyroid Axis in a Letrozole Induced Polycystic (Pco) Rat

  2018cites this paper
• Dermokosmetika für „Anti-Aging“

  2018cites this paper
• Anti-Aging-Strategien

  2018cites this paper
• Dermokosmetika für „Anti-Aging“

  2017cites this paper
• Future Demands Concerning the Epigenetic Relevance of Melatonin and the Circadian System in Gerontology

  2017cites this paper
• Neonatal hypoxic ischemic encephalopathy: an update on disease pathogenesis and treatment

  2017cites this paper
• Increased melatonin levels in aqueous humor of patients with proliferative retinopathy in type 2 diabetes mellitus.

  2016cites this paper
• The aging clock and circadian control of metabolism and genome stability

  2015cites this paper
• Effects of Melatonin on Heartbeat and Possible Identification of a Melatonin Receptor in Drosophila Melanogaster

  2015cites this paper
• Sirtuins, aging, and cardiovascular risks

  2015cites this paper
• Effect of Exogenous Melatonin on Thyroxin e (T 4 ), Thyrotropin (TSH) Hormone Levels and Expression patterns of Melatonin Receptor (MT1 and MT2) Proteins on Thyroid gland during Different age groups of Male and Female Swiss albino Mice

  2015cites this paper
• Regulation of L1 expression and retrotransposition by melatonin and its receptor: implications for cancer risk associated with light exposure at night

  2014cites this paper
• Age dependent nitro-oxidative load and melatonin receptor expression in the spleen and immunity of goat Capra hircus.

  2014cites this paper
• Longevity of Daphnia and the attenuation of stress responses by melatonin

  2014influential citation
• Tryptophan and Melatonin-Enriched Foodstuffs to Improve Antioxidant Status in Aging

  2014cites this paper
• Daily rhythm of blood melatonin concentrations in sheep of different ages

  2013cites this paper
• Neuroprotective Therapies after Perinatal Hypoxic-Ischemic Brain Injury

  2013cites this paper
• Melatonin potentiates running wheel‐induced neurogenesis in the dentate gyrus of adult C3H/HeN mice hippocampus

  2013cites this paper
• Age-related differences in hepatic ischemia/reperfusion: gene activation, liver injury, and protective effect of melatonin.

  2013cites this paper
• Melatonin, the circadian multioscillator system and health: the need for detailed analyses of peripheral melatonin signaling

  2012cites this paper
• Melatonin and Cancer Treatment Life Extension Supports Clinical Trial

  2012cites this paper
• Age dependent expression of melatonin membrane receptor (MT1, MT2) and its role in regulation of nitrosative stress in tropical rodent Funambulus pennanti

  2012cites this paper
• Melatonin-synthesizing enzymes and melatonin receptor in rat thyroid cells.

  2012cites this paper
• A cherry nutraceutical modulates melatonin, serotonin, corticosterone, and total antioxidant capacity levels: effect on ageing and chronotype

  2012cites this paper
• Age-related differences in hepatic ischemia/reperfusion: gene activation, liver injury, and protective effect of melatonin.

  2012cites this paper
• Melatonin, a natural programmed cell death inducer in cancer.

  2012cites this paper
• Beneficio del tratamiento crónico con melatonina frente al daño oxidativo/nitrosativo mitocondrial durante el envejecimiennto en ratones con senescencia acelerada

  2011cites this paper
• Aging and vascular dysfunction: beneficial melatonin effects

  2011cites this paper
• Synergism between melatonin and atorvastatin against endothelial cell damage induced by lipopolysaccharide

  2011cites this paper
• Melatonina en suero durante la primera semana de vida: su relación con la actividad antioxidante en el periodo neonatal

  2011cites this paper
• Lipid peroxidation in relation to ageing and the role of endogenous aldehydes in diabetes and other age-related diseases.

  2010cites this paper
• Melatonin and Cancer Treatment

  2010cites this paper
• Melatonin as the most effective organizer of the rhythm of protein synthesis in hepatocytes in vitro and in vivo

  2010cites this paper
• Antioxidant System and Energy Provision of the Rat Heart during Aging Depend on Illumination Regimen and Are Resistant to Exogenous Melatonin

  2010cites this paper
• Actinic damage and its treatments.

  2010cites this paper
• 9 Neurotoxic Brain Stem Impairment as Proposed Threshold Event in Autistic Regression

  2009cites this paper
• AFRICAN-AMERICAN LONGEVITY ADVANTAGE: MYTH OR REALITY?: A Racial Comparison of Supercentenarian Data

  2009cites this paper
• Melatonin prevents oxidized low‐density lipoprotein‐induced increase of myosin light chain kinase activation and expression in HUVEC through ERK/MAPK signal transduction

  2008cites this paper
• Melatonin in relation to the "strong" and "weak" versions of the free radical theory of aging.

  2008cites this paper
• Melatonin Beyond Its Classical Functions

  2008cites this paper
• Melatonin is able to reduce the apoptotic liver changes induced by aging via inhibition of the intrinsic pathway of apoptosis.

  2007cites this paper
• Melatonin prevents oxidative stress and changes in antioxidant enzyme expression and activity in the liver of aging rats

  2007cites this paper
• Melatonin biosynthesis in the thymus of humans and rats

  2007cites this paper
• Chronic melatonin treatment reduces the age‐dependent inflammatory process in senescence‐accelerated mice

  2007cites this paper
• Research Article Melatonin biosynthesis in the thymus of humans and rats

  2007cites this paper
• Antioxidants do not prevent acrylonitrile-induced toxicity.

  2007cites this paper
• Chapter 31 - Oxidative stress in phagocytic cells: Changes with age and effect of melatonin

  2007cites this paper
• Age-dependent lipopolysaccharide-induced iNOS expression and multiorgan failure in rats: effects of melatonin treatment.

  2006cites this paper
• Biological Implications of Heme Metabolism

  2006cites this paper
• Light pollution, melatonin suppression and cancer growth

  2006cites this paper
• Melatonin and sleep in aging population.

  2005cites this paper
• Melatonin, aging, and age-related diseases

  2005cites this paper
• Melatonin, lipid peroxidation, and age in heterophils from the ring dove (Streptopelia risoria)

  2005cites this paper
• Oral administration of melatonin to old ring doves (Streptopelia risoria) increases plasma levels of melatonin and heterophil phagocytic activity.

  2005cites this paper
• Melatonin reduces prostate cancer cell growth leading to neuroendocrine differentiation via a receptor and PKA independent mechanism

  2005cites this paper
• Dietary supplementation with melatonin reduces levels of amyloid beta‐peptides in the murine cerebral cortex

  2004influential citation
• Protective effect of melatonin on random pattern skin flap necrosis in pinealectomized rat

  2004cites this paper
• Circadian Rhythms, Oxidative Stress, and Antioxidative Defense Mechanisms

  2003influential citation
• Light, timing of biological rhythms, and chronodisruption in man

  2003cites this paper
• [Anti-aging. Facts and visions].

  2003cites this paper
• O R IGINAL AR T ICLE Melatonin supplementation restores cellular proliferation and DNA synthesis in the splenic and thymic lymphocytes of old rats

  2003cites this paper
• Anti-aging

  2003cites this paper
• Melatonin supplementation restores cellular proliferation and DNA synthesis in the splenic and thymic lymphocytes of old rats.

  2003cites this paper
• G Protein-Linked Effector and Second Messenger Systems Involved in Melatonin Signal Transduction

  2003cites this paper