In vivo antioxidative effect of isoquercitrin on cadmium-induced oxidative damage to mouse liver and kidney

No abstract is available for this paper.

• Publication year

  2011

• Venue

  Naunyn-Schmiedeberg's Archives of Pharmacology

• Publication date

  2011-02-19

• Fields of study

  Medicine, Chemistry, Environmental Science

• Identifiers
  DOI 10.1007/s00210-011-0613-2PMID 21336539
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Quercetin protects rat liver against lead-induced oxidative stress and apoptosis.

  2010cited by this paper
• Lipid peroxidation in relation to ageing and the role of endogenous aldehydes in diabetes and other age-related diseases.

  2010cited by this paper
• Isoquercitrin is the most effective antioxidant in the plant Thuja orientalis and able to counteract oxidative-induced damage to a transformed cell line (RGC-5 cells).

  2010cited by this paper
• Mechanisms of cadmium carcinogenesis.

  2009cited by this paper
• Flavonoids, vascular function and cardiovascular protection.

  2009cited by this paper
• Role of oxidative stress in cadmium toxicity and carcinogenesis.

  2009cited by this paper
• A new method for determination of myricetin and quercetin using solid phase microextraction-high performance liquid chromatography-ultra violet/visible system in grapes, vegetables and red wine samples.

  2009cited by this paper
• Biological activity of quercetin-3-O-glucoside, a known plant flavonoid

  2009cited by this paper
• In vitro and in vivo determination of antioxidant activity and mode of action of isoquercitrin and Hyptis fasciculata.

  2009cited by this paper
• Identification of hop polyphenolic components which inhibit prostaglandin E2 production by gingival epithelial cells stimulated with periodontal pathogen.

  2008cited by this paper
• Antioxidant effects of flavonoids used as food additives (purple corn color, enzymatically modified isoquercitrin, and isoquercitrin) on liver carcinogenesis in a rat medium-term bioassay.

  2008cited by this paper
• The Experimental Improvement of Chinese Herbs Scavenging Hydroxyl Radical

  2008cited by this paper
• Determination of the relative contribution of quercetin and its glucosides to the antioxidant capacity of onion by cyclic voltammetry and spectrophotometric methods.

  2008cited by this paper
• Protein Oxidation and DNA–Protein Crosslink Induced by Sulfur Dioxide in Lungs, Livers, and Hearts from Mice

  2007cited by this paper
• Anti-inflammatory activity of quercetin and isoquercitrin in experimental murine allergic asthma

  2007cited by this paper
• Free radicals and antioxidants in normal physiological functions and human disease.

  2007cited by this paper
• Reactive oxygen species scavenging activity of flavone glycosides from Melilotus neapolitana.

  2007cited by this paper
• Research on the measurement of the SOD activity via pyrogallol auto-oxidation

  2006cited by this paper
• The importance of glutathione in oxidative status of Rhizobium leguminosarum biovar viciae under Cd exposure

  2006cited by this paper
• Antioxidant enzymes activity and lipid peroxidation in liver and kidney of rats exposed to cadmium and ethanol.

  2004cited by this paper
• Vasorelaxing effects of flavonoids: investigation on the possible involvement of potassium channels

  2004cited by this paper
• Cadmium inhibits the electron transfer chain and induces reactive oxygen species.

  2004cited by this paper
• Antioxidant activity and phenolic compounds of 112 traditional Chinese medicinal plants associated with anticancer

  2004cited by this paper
• Comparative Effects of Chelating Agents on Lipid Peroxidation in Mice Organs by Acute Exposure to Cadmium

  2003cited by this paper
• A global perspective on cadmium pollution and toxicity in non-occupationally exposed population.

  2003cited by this paper
• Protective effects of dihydropyridine Ca-blockers against endothelial cell oxidative injury due to combined nitric oxide and superoxide.

  2002cited by this paper
• Flavonoids from Hypericum perforatum show antidepressant activity in the forced swimming test.

  2000influential reference
• Liquid chromatography-electrospray ionization mass spectrometry study of the flavonoids of the roots of Astragalus mongholicus and A. membranaceus.

  2000cited by this paper
• Human Nutrition and Metabolism—Research Communication Bioavailabilities of Quercetin-3- Glucoside and Quercetin-4*- Glucoside Do Not Differ in Humans

  2000cited by this paper
• The effects of plant flavonoids on mammalian cells: implications for inflammation, heart disease, and cancer.

  2000cited by this paper
• Quantitation of oxidative damage to tissue proteins.

  1999cited by this paper
• Glutathione depletion and oxidative damage in mitochondria following exposure to cadmium in rat liver and kidney.

  1999cited by this paper
• Protective effects of some flavonoids on the renal cellular membrane.

  1999cited by this paper
• Dietary phytoestrogens and their role in hormonally dependent disease.

  1998cited by this paper
• Iron homeostasis, oxidative stress, and DNA damage.

  1997cited by this paper
• Enzyme activity alteration by cadmium administration to rats: the possibility of iron involvement in lipid peroxidation.

  1997cited by this paper
• Cadmium-induced production of superoxide anion and nitric oxide, DNA single strand breaks and lactate dehydrogenase leakage in J774A.1 cell cultures.

  1996influential reference
• Structure-antioxidant activity relationships of flavonoids and phenolic acids.

  1996cited by this paper
• Superoxide production by mitochondria in the presence of nitric oxide forms peroxynitrite

  1996cited by this paper
• Oxidative mechanisms in the toxicity of metal ions.

  1995cited by this paper
• The ecotoxicological significance of cadmium intake and residues in terrestrial small mammals.

  1994cited by this paper
• Optimized steps in fluorometric determination of thiobarbituric acid-reactive substances in serum: importance of extraction pH and influence of sample preservation and storage.

  1993cited by this paper
• DNA damage by drugs and radiation: what is important and how is it measured?

  1992cited by this paper
• Biological roles of nitric oxide.

  1992cited by this paper
• Molecular mechanisms of nickel carcinogenesis.

  1991cited by this paper
• On the occurrence of flavonol and flavone glycosides in vegetables

  1988cited by this paper
• A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding.

  1976cited by this paper
• FORMATION AND STABILITY OF INORGANIC COMPLEXES IN SOLUTION

  year unknowncited by this paper

• Targeting the AMP-activated protein kinase pathway: the active metabolites of botanical drugs represent potential strategies for treating metabolic-associated fatty liver disease

  2026cites this paper
• Metabolomics and Transcriptomics Analyses Explore the Genes Related to the Biosynthesis of Antioxidant Active Ingredient Isoquercetin

  2026cites this paper
• Oral Administration of Cadmium Chloride Induces Oxidative Stress, DNA Damage and Histopathological Changes in Rat Intestine: A Dose‐Dependent Study

  2025cites this paper
• Isoquercitrin Attenuates Oxidative Liver Damage Through AMPK-YAP Signaling: An Integrative In Silico, In Vitro, and In Vivo Study

  2025cites this paper
• Profiling the Phytochemicals of Orostachys margaritifolia: Biological Activities, LC-ESI/MS, and HPLC Analyses

  2024cites this paper
• Dietary Isoquercetin Reduces Hepatic Cholesterol and Triglyceride in NAFLD Mice by Modulating Bile Acid Metabolism via Intestinal FXR-FGF15 Signaling.

  2023cites this paper
• Oral chronic toxicity and carcinogenicity study of alpha-glycosyl isoquercitrin (AGIQ) in Sprague Dawley rats.

  2023cites this paper
• Translatomics and physiological analyses of the detoxification mechanism of green alga Chlamydomonas reinhardtii to cadmium toxicity.

  2023cites this paper
• Bioactive compounds from Actinidia arguta fruit as a new strategy to fight glioblastoma.

  2023cites this paper
• Lack of skin sensitization hazard potential for alpha-glycosyl isoquercitrin (AGIQ) utilizing the Local Lymph Node Assay

  2022cites this paper
• Genotoxicity and mutagenicity evaluation of isoquercitrin-γ-cyclodextrin molecular inclusion complex using Ames test and a combined micronucleus and comet assay in rats.

  2022cites this paper
• Isoquercitrin from Apocynum venetum L. produces an anti-obesity effect on obese mice by targeting C-1-tetrahydrofolate synthase, carbonyl reductase, and glutathione S-transferase P and modification of the AMPK/SREBP-1c/FAS/CD36 signaling pathway in mice in vivo.

  2022cites this paper
• Possible ameliorating effect of isoquercetin on diethylnitrosamine-induced hepatocellular carcinoma in albino mice

  2022influential citation
• Encapsulation of Flavonoids in Nanocarriers

  2022cites this paper
• Simultaneous quantification of 18 bioactive constituents in Ziziphus jujuba fruits by HPLC coupled with a chemometric method

  2022cites this paper
• Optimized enzymatic synthesis of digestive resistant anomalous isoquercitrin glucosides using amylosucrase and response surface methodology

  2021cites this paper
• Nephroprotective potential of Anogeissus latifolia Roxb. (Dhava) against gentamicin-induced nephrotoxicity in rats.

  2021cites this paper
• 13-Weeks subchronic toxicity of isoquercitrin-γ-cyclodextrin (IQC-γCD) molecular inclusion complex in Sprague-Dawley rats.

  2021cites this paper
• BCRP/ABCG2 Transporter Regulates Accumulation of Cadmium in Kidney Cells: Role of the Q141K Variant in Modulating Nephrotoxicity

  2021influential citation
• alpha-Glycosyl Isoquercitrin (AGIQ) and its Lack of Carcinogenicity in rasH2 mice.

  2021cites this paper
• Isoquercitrin induces apoptosis and autophagy in hepatocellular carcinoma cells via AMPK/mTOR/p70S6K signaling pathway

  2020cites this paper
• Bilberry (Vaccinium myrtillus L.) Extracts Comparative Analysis Regarding Their Phytonutrient Profiles, Antioxidant Capacity along with the In Vivo Rescue Effects Tested on a Drosophila melanogaster High-Sugar Diet Model

  2020cites this paper
• Embryo-fetal developmental toxicity study of alpha-glycosyl isoquercitrin administered orally to New Zealand White rabbits

  2020cites this paper
• Isoquercitrin Ameliorates Cisplatin-Induced Nephrotoxicity Via the Inhibition of Apoptosis, Inflammation, and Oxidative Stress

  2020cites this paper
• Identification of compound causing yellow bone discoloration following alpha-glycosyl isoquercitrin exposure in Sprague–Dawley rats

  2020cites this paper
• Isoquercitrin Attenuates Renal Ischemia/Reperfusion Injury Through Antioxidation, Anti-inflammation, and Antiapoptosis in Mice.

  2020cites this paper
• Serum metabonomics analysis of quercetin against the toxicity induced by cadmium in rats

  2020cites this paper
• Genome-Protecting Compounds as Potential Geroprotectors

  2020cites this paper
• Ten-day and four-week toxicity and toxicokinetics studies of alpha-glycosyl isoquercitrin in juvenile Göttingen minipigs

  2019cites this paper
• Acer okamotoanum and isoquercitrin improve cognitive function via attenuation of oxidative stress in high fat diet- and amyloid beta-induced mice.

  2019cites this paper
• Isoquercitrin, a flavonoid glucoside, exerts a positive effect on osteogenesis in vitro and in vivo.

  2019cites this paper
• High-efficiency enzymatic production of α-isoquercitrin glucosides by amylosucrase from Deinococcus geothermalis.

  2019cites this paper
• Towards a modern approach to traditional use: in vitro and in vivo evaluation of Alchemilla vulgaris L. gel wound healing potential.

  2019cites this paper
• Application of Deep Eutectic Solvents to Prepare Mixture Extracts of Three Long-Lived Trees with Maximized Skin-Related Bioactivities

  2019cites this paper
• Nano-composites chitosan-curcumin synergistically inhibits the oxidative stress induced by toxic metal cadmium.

  2018cites this paper
• Sulfate supply enhances cadmium tolerance in Vicia faba L. plants

  2018cites this paper
• Mahonia Aquifolium Flowers Extract Effects in Acute Experimental Inflammation

  2018cites this paper
• Comprehensive evaluation of the flavonol anti-oxidants, alpha-glycosyl isoquercitrin and isoquercitrin, for genotoxic potential.

  2018cites this paper
• Simultaneous determination and pharmacokinetic study of three flavonoid glycosides in rat plasma by LC-MS/MS after oral administration of Rubus chingii Hu extract.

  2018cites this paper
• Isoquercitrin Attenuated Cardiac Dysfunction Via AMPK&agr;‐Dependent Pathways in LPS‐Treated Mice

  2018cites this paper
• Isoquercitrin, ingredients in Tetrastigma hemsleyanum Diels et Gilg, inhibits hepatocyte growth factor/scatter factor-induced tumor cell migration and invasion

  2018cites this paper
• B-factor-saturation mutagenesis as a strategy to increase the thermostability of α-L-rhamnosidase from Aspergillus terreus.

  2018cites this paper
• Chemical study and evaluation of antioxidant activity and α-glucosidase inhibition of Myrciaria strigipes O . Berg ( Myrtaceae )

  2018cites this paper
• Isoquercetin Improves Hepatic Lipid Accumulation by Activating AMPK Pathway and Suppressing TGF-β Signaling on an HFD-Induced Nonalcoholic Fatty Liver Disease Rat Model

  2018cites this paper
• Cytoprotective effects of dietary flavonoids against cadmium‐induced toxicity

  2017cites this paper
• Anti-adipogenic effects of Tropaeolum majus (nasturtium) ethanol extract on 3T3-L1 cells

  2017cites this paper
• Centaurium erythraea methanol extract protects red blood cells from oxidative damage in streptozotocin-induced diabetic rats.

  2017cites this paper
• Biotransformation of Rutin Using Crude Enzyme from Rhodopseudomonas palustris

  2017cites this paper
• Maternal blood cadmium, lead and arsenic levels, nutrient combinations, and offspring birthweight

  2017cites this paper
• The Stoichiometry of Isoquercitrin Complex with Iron or Copper Is Highly Dependent on Experimental Conditions

  2017cites this paper
• Reactive oxygen species: sources, consequences and targeted therapy in type 2 diabetes

  2017cites this paper
• Chemical characterization of the main bioactive constituents from fruits of Ziziphus jujuba.

  2016cites this paper
• Protective effects of quercetin glycosides, rutin, and isoquercetrin against 6-hydroxydopamine (6-OHDA)-induced neurotoxicity in rat pheochromocytoma (PC-12) cells

  2016cites this paper
• Amelioration of particulate matter-induced oxidative damage by vitamin c and quercetin in human bronchial epithelial cells.

  2016cites this paper
• Evaluation of the wound healing potential of isoquercetin-based cream on scald burn injury in rats

  2016cites this paper
• Nitric oxide and Kir6.1 potassium channel mediate isoquercitrin-induced endothelium-dependent and independent vasodilation in the mesenteric arterial bed of rats.

  2016cites this paper
• Ninety-day toxicity and single-dose toxicokinetics study of alpha-glycosyl isoquercitrin in Sprague-Dawley rats.

  2016cites this paper
• Review of anticancer mechanisms of isoquercitin.

  2016cites this paper
• Pyropia yezoensis glycoprotein regulates antioxidant status and prevents hepatotoxicity in a rat model of D-galactosamine/lipopolysaccharide-induced acute liver failure.

  2016cites this paper
• Hepatoprotective effect of isoquercitrin against acetaminophen-induced liver injury.

  2016cites this paper
• Traditional usages, botany, phytochemistry, biological activity and toxicology of Tropaeolum majus L. - A review

  2016cites this paper
• WITHDRAWN: Simultaneous determination of astragalin, isoquercitrin, kaempferol-3-O-rutinoside and tiliroside in rat plasma by LC–MS/MS and its application to a pharmacokinetic study after oral administration of Rubus chingii Hu extract

  2016cites this paper
• Investigation of cadmium-induced apoptosis and the protective effect of N-acetylcysteine in BRL 3A cells.

  2016cites this paper
• An effective biphase system accelerates hesperidinase-catalyzed conversion of rutin to isoquercitrin

  2015cites this paper
• Isoquercitrin inhibits the progression of pancreatic cancer in vivo and in vitro by regulating opioid receptors and the mitogen-activated protein kinase signalling pathway.

  2015cites this paper
• Properties and applications of flavonoid metal complexes

  2015cites this paper
• Extraction and Structural Characterization of Flavonoids from Twigs of Sophora japonica

  2015cites this paper
• Apocynum venetum Attenuates Acetaminophen-Induced Liver Injury in Mice.

  2015cites this paper
• A protective role of methionine-R-sulfoxide reductase against cadmium in Schizosaccharomyces pombe

  2014cites this paper
• Particulate matters collected from ceramic factories in Lampang Province affecting rat lungs

  2014cites this paper
• Effects of avermectin on immune function and oxidative stress in the pigeon spleen.

  2014cites this paper
• Isoquercitrin activates the AMP–activated protein kinase (AMPK) signal pathway in rat H4IIE cells

  2014cites this paper
• Plants Used in the Management of Diabetic Complications

  2014cites this paper
• Isoquercitrin: pharmacology, toxicology, and metabolism.

  2014cites this paper
• Reduced Oxidative Stress Contributes to the Lipid Lowering Effects of Isoquercitrin in Free Fatty Acids Induced Hepatocytes

  2014cites this paper
• Study on the Synthesis of Isoquercitrin by Enzymatic Partial Hydrolysis

  2014cites this paper
• Chemical and biological assessment of Ziziphus jujuba fruits from China: different geographical sources and developmental stages.

  2013cites this paper
• On the effect of chelating agents and antioxidants on cadmium-induced organ toxicity. An overview

  2013cites this paper
• Identification of isoquercitrin metabolites produced by human intestinal bacteria using UPLC-Q-TOF/MS.

  2013cites this paper
• Recent studies on flavonoids and their antioxidant activities

  2013cites this paper
• Study of the physiological characteristics of the medicinal mushroom Trametes pubescens (higher Basidiomycetes) during the laccase-producing process.

  2013cites this paper
• Cadmium‐induced hepatotoxicity and its abrogation by thymoquinone

  2012cites this paper
• Selective hydrolysis by commercially available hesperidinase for isoquercitrin production

  2012cites this paper
• The Flavonoid Isoquercitrin Promotes Neurite Elongation by Reducing RhoA Activity

  2012cites this paper
• Proanthocyanidin prevents myocardial ischemic injury in adult rats

  2011cites this paper
• Yunnan edible flowers and their potential in future foods: focus on ethnological applications, chemical and pharmacological research

  year unknowncites this paper