Manganese oxidation state and its implications for toxicity.

No abstract is available for this paper.

• Publication year

  2002

• Venue

  Chemical Research in Toxicology

• Publication date

  2002-08-29

• Fields of study

  Medicine, Chemistry, Environmental Science

• Identifiers
  DOI 10.1021/TX025525EPMID 12230404
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Chronic manganese poisoning: A neuropathological study with determination of manganese distribution in the brain

  2004cited by this paper
• Iron overload following manganese exposure in cultured neuronal, but not neuroglial cells.

  2001cited by this paper
• Differential cytotoxicity of Mn(II) and Mn(III): special reference to mitochondrial [Fe-S] containing enzymes.

  2001cited by this paper
• The neurobehavioral effects of subchronic manganese exposure in the presence and absence of pre-parkinsonism.

  2000cited by this paper
• Aluminum uptake and effects on transferrin mediated iron uptake in primary cultures of rat neurons, astrocytes and oligodendrocytes.

  1999cited by this paper
• Environmental effects and exposures to manganese from use of methylcyclopentadienyl manganese tricarbonyl (MMT) in gasoline.

  1999cited by this paper
• Manganese and calcium transport in mitochondria: implications for manganese toxicity.

  1999cited by this paper
• Could mitochondrial dysfunction play a role in manganese toxicity?

  1999cited by this paper
• Diorthosubstituted polychlorinated biphenyls in caudate nucleus in Parkinson's disease.

  1998cited by this paper
• Probing the active site of human manganese superoxide dismutase: the role of glutamine 143.

  1998cited by this paper
• Structural basis for the negative allostery between Ca2+‐ and Mg2+ ‐binding in the intracellular Ca2+ ‐receptor calbindin D9k

  1997cited by this paper
• Superoxide Production by the Mitochondrial Respiratory Chain

  1997cited by this paper
• Ambient air concentrations of fine (PM2.5) manganese in U.S. national parks and in California and Canadian cities: the possible impact of adding MMT to unleaded gasoline.

  1997cited by this paper
• Occupational exposures to metals as risk factors for Parkinson's disease

  1997cited by this paper
• Manganese intoxication in the rhesus monkey

  1996cited by this paper
• Manganese-induced reactive oxygen species: comparison between Mn+2 and Mn+3.

  1995cited by this paper
• Vulnerability of mitochondrial complex I in PC12 cells exposed to manganese.

  1995cited by this paper
• Metal ion dependence of oligosaccharyl transferase: implications for catalysis.

  1995cited by this paper
• Cellular neurotoxicity of trivalent manganese bound to transferrin or pyrophosphate studied in human neuroblastoma (SH-SY5Y) cell cultures.

  1995cited by this paper
• Manganese injection into the rat striatum produces excitotoxic lesions by impairing energy metabolism.

  1993cited by this paper
• Parkinson's disease mortality and the industrial use of heavy metals in Michigan

  1993cited by this paper
• EcoRV restriction endonuclease: communication between DNA recognition and catalysis.

  1992cited by this paper
• Stable isotope labeling of lead compartments in rats with ultralow lead concentrations.

  1992cited by this paper
• Distribution of manganese in rat pancreas and identification of its primary binding protein as pro-carboxypeptidase B.

  1991cited by this paper
• Lead exposure during advanced age: alterations in kinetics and biochemical effects.

  1990cited by this paper
• Manganese and calcium efflux kinetics in brain mitochondria. Relevance to manganese toxicity.

  1990cited by this paper
• Manganese poisoning and the attack of trivalent manganese upon catecholamines.

  1987cited by this paper
• Methylcyclopentadienyl manganese tricarbonyl (MMT) in petrol: the toxicological issues.

  1987cited by this paper
• Manganese ions, oxidation reactions and the superoxide radical.

  1984cited by this paper
• Glutamine synthetase: the major Mn(II) enzyme in mammalian brain.

  1984cited by this paper
• Manganese and extrapyramidal disorders (a critical review and tribute to Dr. George C. Cotzias).

  1984cited by this paper
• Glutathione-dependent inhibition of lipid peroxidation by a soluble, heat-labile factor not glutathione peroxidase.

  1981cited by this paper
• The mechanism of aconitase action. 3. Detection and properties of enzyme-metal-substrate and enzyme-metal-inhibitor bridge complexes with manganese(II) and iron(II).

  1972cited by this paper
• The mechanism of aconitase action. II. Magnetic resonance studies of the complexes of enzyme, manganese(II), iron(II), and substrates.

  1971cited by this paper
• The chromium, manganese, and cobalt complexes of transferrin.

  1969cited by this paper
• Mitochondrial hexokinase. Release, rebinding, and location.

  1967cited by this paper
• Mechanism of aconitase action. I. The hydrogen transfer reaction.

  1967cited by this paper
• Lactic Dehydrogenase Activity in Blood.∗

  1955cited by this paper
• The oxidation of manganese by illuminated chloroplast preparations.

  1955cited by this paper
• The oxidation of beta-(3-indolyl) propionic acid and gamma-(3-indolyl)-n-butyric acid by peroxidase and Mn2+.

  1955cited by this paper

• Tumor Microenvironment-Activated Manganese Nanomaterials for Precision Theranostics

  2026cites this paper
• Critical minerals extraction from geothermal brines

  2025cites this paper
• Cell Death and Proliferation Variability Caused by Different Dust Clay Minerals Using the Single‐Cell Method

  2025cites this paper
• Redox determines greenhouse gas production kinetics and metabolic traits in water-saturated thawing permafrost peat

  2025cites this paper
• Role of manganese in brain health and disease: focus on oxidative stress.

  2025cites this paper
• Chemical- and photo-activation of protein-protein thiol-ene coupling for protein profiling

  2025cites this paper
• The cytotoxic effect of Mn2+/Mn3+-doped Simonkolleite nano-platelets on human fibroblasts and mouse melanoma cells

  2025cites this paper
• A comprehensive survey of Mn(I) carbonyls as CO-releasing molecules reported over the last two decades.

  2024cites this paper
• A Tale of Two Cities in Fluorescent Sensing of Carbon Monoxide: Probes That Detect CO and Those That Detect Only Chemically Reactive CO Donors (CORMs), but Not CO

  2024cites this paper
• Manganese: From Soil to Human Health—A Comprehensive Overview of Its Biological and Environmental Significance

  2024cites this paper
• Modeling the vulnerability of water resources to pollution in a typical mining area, SE Nigeria using speciation, geospatial, and multi-path human health risk modeling approaches

  2024cites this paper
• Death following cylindrical battery ingestion associated with toxic manganese levels

  2024cites this paper
• Examining the Oxidation States of Metals in Aerosols Emitted by Electronic Cigarettes.

  2024cites this paper
• Study on the adsorption performance of zeolite imidazole frameworks materials for Co(II) and Mn(II) in solution

  2024cites this paper
• The Protective Role of Sesame Oil against Parkinson's-Like Disease Induced by Manganese in Rats.

  2024cites this paper
• Mechanism of Permanganate Biosorption by Fermentation Biowaste

  2023cites this paper
• Metal Organic Frameworks of ANA Topology as an Effective Adsorbent for Co(II) and Mn(II) in Solution

  2023cites this paper
• A State-of-the-Science Review on Metal Biomarkers

  2023cites this paper
• Heavy metal deposition and parameter change of soft contact lenses by exposure to particulate matter

  2023cites this paper
• Transition Metal Sensing with Nitrogenated Holey Graphene: A First-Principles Investigation

  2023cites this paper
• Study on the adsorption performance of zeolitic imidazolate framework-8 (ZIF-8) for Co2+ and Mn2+

  2022cites this paper
• Development of novel Escherichia coli cell-based biosensors to monitor Mn(II) in environmental systems

  2022cites this paper
• General chemistry of metals, sampling, analytical methods, and speciation

  2022cites this paper
• Bone manganese is a sensitive biomarker of ongoing elevated manganese exposure, but does not accumulate across the lifespan.

  2021cites this paper
• The impact of environmental and occupational exposures of manganese on pulmonary, hepatic, and renal functions

  2021cites this paper
• Development of an Effective Tumor-Targeted Contrast Agent for Magnetic Resonance Imaging Based on Mn/H-Ferritin Nanocomplexes

  2021cites this paper
• The Functions of ZIP8, ZIP14, and ZnT10 in the Regulation of Systemic Manganese Homeostasis

  2020cites this paper
• Manganese (II)-imidazole complexes of the non-steroidal anti-inflammatory drug mefenamic acid: Synthesis, and structural studies

  2020cites this paper
• Roles and requirements of trace elements in tilapia nutrition: Review

  2020cites this paper
• Intracellular Metal Speciation in Streptococcus sanguinis Establishes SsaACB as Critical for Redox Maintenance.

  2020cites this paper
• Multi-Elemental Characterization of PM0.4–0.7 and PM1.1–2.1 in the Ambient Air of Isfahan (Iran) Complemented by the Speciation of Mn and Cr Using SR-XANES

  2020cites this paper
• Positron impact ionization of alkali atoms

  2020cites this paper
• Tau folding and cytotoxicity of neuroblastoma cells in the presence of manganese oxide nanoparticles: Biophysical, molecular dynamics, cellular, and molecular studies.

  2019cites this paper
• Sex differences in subacute manganese intoxication: Oxidative parameters and metal deposition in peripheral organs of adult Wistar rats

  2019cites this paper
• Acute effects of methcathinone and manganese in mice: A dose response study

  2019cites this paper
• Synchrotron radiation total reflection X-ray fluorescence (SR-TXRF) and X-ray absorption near edge structure (XANES) of fractionated air particulates collected from Jeddah, Saudi Arabia

  2018cites this paper
• Manganese metabolism in humans.

  2018cites this paper
• Terminology of elemental speciation – An IUPAC perspective

  2017cites this paper
• Cellular Fates of Manganese(II) Pentaazamacrocyclic Superoxide Dismutase (SOD) Mimetics: Fluorescently Labeled MnSOD Mimetics, X-ray Absorption Spectroscopy, and X-ray Fluorescence Microscopy Studies.

  2017cites this paper
• Manganese‐induced sex‐specific gut microbiome perturbations in C57BL/6 mice

  2017cites this paper
• A study of cytocompatibility and degradation of iron-based biodegradable materials

  2016cites this paper
• MnTE-2-PyP modulates thiol oxidation in a hydrogen peroxide-mediated manner in a human prostate cancer cell.

  2016cites this paper
• Modification of waste coal gangue and its application in the removal of Mn(2+) from aqueous solution.

  2016cites this paper
• Fundamental study of the design and development of iron based alloys for biodegradable implant device applications

  2016cites this paper
• Modification of waste coal gangue and its application in the removal of Mn2þ from aqueous solution

  2016cites this paper
• Biomedical and Pharmaceutical Applications

  2016cites this paper
• Epigenetics Involvement In Parkinson's Disease And Manganese-Induced Neurotoxicity

  2015cites this paper
• Manganese Toxicity Upon Overexposure: a Decade in Review

  2015cites this paper
• Ultrastructural Changes of Caudate Nucleus in Mice Chronically Treated with Manganese

  2015cites this paper
• Manganese Is Essential for Neuronal Health.

  2015cites this paper
• Manganese and its speciation in environmental samples using hyphenated techniques: A review

  2015cites this paper
• Mechanisms of Heavy Metal Neurotoxicity: Lead and Manganese

  2015cites this paper
• General Chemistry, Sampling, Analytical Methods, and Speciation

  2015cites this paper
• Formaldehyde catalytic oxidation over hydroxyapatite modified with various organic molecules

  2014cites this paper
• Possible sites of copper located on hydroxyapatite structure and the identification of active sites for formaldehyde oxidation

  2014cites this paper
• Mechanisms of lead and manganese neurotoxicity.

  2013cites this paper
• On the cytocompatibility of biodegradable Fe-based alloys.

  2013cites this paper
• Improved Visualization of Neuronal Injury Following Glial Activation by Manganese Enhanced MRI

  2013influential citation
• Manganese in Neurodegeneration

  2013cites this paper
• Use of X-Ray Absorption Spectroscopy ( XAS ) to Speciate Manganese in Airborne Particulate Matter from 5 Counties Across the US

  2013cites this paper
• Development and characterization of biodegradable Fe-based alloys for temporary medical applications

  2012cites this paper
• Manganese Speciation Related to Neurotoxicity in Humans

  2012cites this paper
• Protective effects of dietary fibre against manganese-induced neurobehavioral aberrations in rats

  2012cites this paper
• Use of X-ray absorption spectroscopy to speciate manganese in airborne particulate matter from five counties across the United States.

  2012cites this paper
• Initial Steps of Photosystem II de Novo Assembly and Preloading with Manganese Take Place in Biogenesis Centers in Synechocystis[C][W]

  2012cites this paper
• Hardening of bio-silica in sponge spicules involves an aging process after its enzymatic polycondensation: evidence for an aquaporin-mediated water absorption.

  2011cites this paper
• Manganese accumulation in the CNS and associated pathologies

  2011cites this paper
• ENVIRONMENTAL ASPECT OF MANGANESE CHEMISTRY

  2010cites this paper
• Isolation and characterization of a manganese oxidizing bacterium from the Mediterranean marine sponge Suberites domuncula .

  2010cites this paper
• Aquaporin‐4 in manganese‐treated cultured astrocytes

  2010influential citation
• Mn2+ exerts stronger structural effects than the Mn-citrate complex on the human erythrocyte membrane and molecular models.

  2010cites this paper
• Assessment of Certain Essential Elements in Some Common Edibles from Dadara and Agyathuri Villages of Kamrup District of Assam

  2010cites this paper
• Manganese-induced dopaminergic neurodegeneration: insights into mechanisms and genetics shared with Parkinson's disease.

  2009cites this paper
• Manganese Flux Across the Blood–Brain Barrier

  2009cites this paper
• Intracellular Ca2+- and Mn2+-transport ATPases.

  2009cites this paper
• Manganês: o papel do fracionamento químico e da especiação como determinantes de seu comportamento geoquímico e neurotóxico nos organismos em desenvolvimento

  2009cites this paper
• Ceruloplasmin alters the tissue disposition and neurotoxicity of manganese, but not its loading onto transferrin.

  2009influential citation
• Studies on biologically important copper(II) / manganese(II) / uranyl(II) – norvaline binary complexes

  2008cites this paper
• Manganese neurotoxicity: A bioinorganic chemist’s perspective

  2008cites this paper
• Manganese and Iron Binding to Human Transferrin

  2007cites this paper
• Development of a Manganese Speciation Method for Atmospheric Aerosols in Biologically and Environmentally Relevant Fluids

  2007cites this paper
• Other Heavy Metals

  2007cites this paper
• Manganese species from human serum, cerebrospinal fluid analyzed by size exclusion chromatography-, capillary electrophoresis coupled to inductively coupled plasma mass spectrometry.

  2007cites this paper
• Speciation and toxicological relevance of manganese in humans.

  2007cites this paper
• Manganese speciation in human cerebrospinal fluid using CZE coupled to inductively coupled plasma MS

  2007cites this paper
• Manganese induces cell swelling in cultured astrocytes.

  2007cites this paper
• Manganese enhances peroxynitrite and leukotriene E4 formation in bovine aortic endothelial cells exposed to arsenic

  2007cites this paper
• Size characterization of manganese species from human serum and cerebrospinal fluid using size exclusion chromatography coupled to inductively coupled plasma mass spectrometry

  2007cites this paper
• The Speciation of Metals in Mammals Influences Their Toxicokinetics and Toxicodynamics and Therefore Human Health Risk Assessment

  2006cites this paper
• Analysis of size characterized manganese species from liver extracts using capillary zone electrophoresis coupled to inductively coupled plasma mass spectrometry (CZE-ICP-MS).

  2006cites this paper
• Continuous multi-element (Cu, Mn, Ni, Se) monitoring in saline and cell suspension using on-line microdialysis coupled with simultaneous electrothermal atomic absorption spectrometry.

  2006cites this paper
• Brain accumulation and toxicity of Mn(II) and Mn(III) exposures.

  2006influential citation
• Manganese oxidation state mediates toxicity in PC12 cells.

  2005cites this paper
• Manganese toxicokinetics at the blood-brain barrier.

  2004cites this paper
• Manganese toxicity upon overexposure

  2004cites this paper
• Antioxidant properties of tea investigated by EPR spectroscopy.

  2003cites this paper
• Regulation of manganese uptake in Synechocystis 6803 by RfrA, a member of a novel family of proteins containing a repeated five-residues domain.

  2003cites this paper
• Neutral-Atom Electron Configurations

  year unknowncites this paper