Network analysis in the investigation of chronic respiratory diseases. From basics to application.

No abstract is available for this paper.

• Publication year

  2014

• Venue

  American Journal of Respiratory and Critical Care Medicine

• Publication date

  2014-10-31

• Fields of study

  Biology, Medicine, Computer Science

• Identifiers
  DOI 10.1164/rccm.201403-0421PPPMID 25254605
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Network medicine analysis of COPD multimorbidities

  2014cited by this paper
• Network medicine, multimorbidity and the lung in the elderly

  2014cited by this paper
• A network framework of cultural history

  2014cited by this paper
• Systemic Inflammatory Response to Smoking in Chronic Obstructive Pulmonary Disease: Evidence of a Gender Effect

  2014cited by this paper
• A diVIsive Shuffling Approach (VIStA) for gene expression analysis to identify subtypes in Chronic Obstructive Pulmonary Disease

  2014cited by this paper
• RCytoscape: tools for exploratory network analysis

  2013cited by this paper
• Cyrface: An interface from Cytoscape to R that provides a user interface to R packages

  2013cited by this paper
• Distinct transcriptional regulatory modules underlie STAT3’s cell type-independent and cell type-specific functions

  2013cited by this paper
• Integrative approaches for finding modular structure in biological networks

  2013influential reference
• CyTargetLinker: A Cytoscape App to Integrate Regulatory Interactions in Network Analysis

  2013cited by this paper
• Application of ’omics technologies to biomarker discovery in inflammatory lung diseases

  2013influential reference
• Beyond the diagnosis of idiopathic pulmonary fibrosis; the growing role of systems biology and stratified medicine

  2013cited by this paper
• Systematic identification of transcriptional regulatory modules from protein–protein interaction networks

  2013cited by this paper
• Network analysis identifies a putative role for the PPAR and type 1 interferon pathways in glucocorticoid actions in asthmatics

  2012cited by this paper
• Towards Systems Biology of Pulmonary Hypertension

  2012cited by this paper
• Revolutionizing medicine in the 21st century through systems approaches.

  2012cited by this paper
• Abnormal lung aging in chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis.

  2012cited by this paper
• Transcription factors: from enhancer binding to developmental control

  2012cited by this paper
• Integrative systems biology approaches in asthma pharmacogenomics.

  2012cited by this paper
• Joint Bayesian inference of condition-specific miRNA and transcription factor activities from combined gene and microRNA expression data

  2012cited by this paper
• MicroRNA-21 Integrates Pathogenic Signaling to Control Pulmonary Hypertension: Results of a Network Bioinformatics Approach

  2012cited by this paper
• Interactome networks and human disease.

  2011cited by this paper
• Systems medicine and integrated care to combat chronic noncommunicable diseases

  2011cited by this paper
• Addressing the complexity of chronic obstructive pulmonary disease: from phenotypes and biomarkers to scale-free networks, systems biology, and P4 medicine.

  2011cited by this paper
• A Systems Biology Approach Identifies Molecular Networks Defining Skeletal Muscle Abnormalities in Chronic Obstructive Pulmonary Disease

  2011cited by this paper
• DisGeNET: a Cytoscape plugin to visualize, integrate, search and analyze gene-disease networks

  2010cited by this paper
• Metabolic Network Analysis of Pseudomonas aeruginosa during Chronic Cystic Fibrosis Lung Infection

  2010cited by this paper
• A survey of current software for network analysis in molecular biology

  2010cited by this paper
• Network medicine: a network-based approach to human disease

  2010cited by this paper
• The use of network analyses for elucidating mechanisms in cardiovascular disease.

  2010cited by this paper
• Modelling treatment effects in a clinical Bayesian network using Boolean threshold functions

  2009cited by this paper
• Chronic lung diseases

  2009cited by this paper
• Delineation of a Gene Network Underlying the Pulmonary Response to Oxidative Stress in Asthma

  2009cited by this paper
• A functional and regulatory map of asthma.

  2008cited by this paper
• A protein interaction network associated with asthma.

  2008cited by this paper
• minet: A R/Bioconductor Package for Inferring Large Transcriptional Networks Using Mutual Information

  2008cited by this paper
• Biological robustness

  2008cited by this paper
• Towards systems biology of human pulmonary fibrosis.

  2007cited by this paper
• Network motifs: theory and experimental approaches

  2007cited by this paper
• The human disease network

  2007cited by this paper
• Reverse engineering of regulatory networks in human B cells

  2005cited by this paper
• Interactome-transcriptome analysis reveals the high centrality of genes differentially expressed in lung cancer tissues

  2005cited by this paper
• Causal Protein-Signaling Networks Derived from Multiparameter Single-Cell Data

  2005cited by this paper
• Bioconductor: open software development for computational biology and bioinformatics

  2004cited by this paper
• Cytoscape: a software environment for integrated models of biomolecular interaction networks.

  2003cited by this paper
• Discovering regulatory and signalling circuits in molecular interaction networks

  2002cited by this paper
• Elvira: An Environment for Creating and Using Probabilistic Graphical Models

  2002cited by this paper
• HUMAN DISEASE

  1957cited by this paper
• Journal of Asthma and Allergy Dovepress Network Analysis of Single Nucleotide Polymorphisms in Asthma

  year unknowncited by this paper
• Bioinformatics Applications Note Systems Biology Bionet: an R-package for the Functional Analysis of Biological Networks

  year unknowncited by this paper
• Interactome Networks and Human Disease

  year unknowncited by this paper

• Network analysis of chronic disease among middle-aged and older adults in China: a nationwide survey

  2025cites this paper
• Applying precision medicine principles to the management of multimorbidity: the utility of comorbidity networks, graph machine learning, and knowledge graphs

  2024cites this paper
• Evaluation of the multimorbidity network and its relationship with clinical phenotypes in chronic obstructive pulmonary disease: The GALAXIA study

  2022cites this paper
• Pathogenesis of chronic obstructive pulmonary disease: understanding the contributions of gene-environment interactions across the lifespan.

  2022cites this paper
• Inhaled Steroids, Circulating Eosinophils, Chronic Airway Infection and Pneumonia Risk in Chronic Obstructive Pulmonary Disease: A Network Analysis.

  2020cites this paper
• Expression of SARS-CoV-2 receptor ACE2 and coincident host response signature varies by asthma inflammatory phenotype

  2020cites this paper
• Respiratory Function Testing in the Era of Precision Medicine

  2020cites this paper
• Dissociation between airway and systemic autoantibody responses in chronic obstructive pulmonary disease

  2020cites this paper
• Sputum and serum autoantibody profiles and their clinical correlation patterns in COPD patients with and without eosinophilic airway inflammation

  2020cites this paper
• Treatable traits: a new paradigm for 21st century management of chronic airway diseases: Treatable Traits Down Under International Workshop report

  2019cites this paper
• Identification of clinically relevant subgroups of COPD based on airway and circulating autoantibody profiles.

  2019cites this paper
• Prospective observational study in patients with obstructive lung disease: NOVELTY design

  2019cites this paper
• Lessons from a Life: The Manuel Tapia Lecture 2018.

  2019cites this paper
• An integrative methodology based on protein-protein interaction networks for identification and functional annotation of disease-relevant genes applied to channelopathies

  2019cites this paper
• A Systems Medicine approach to multimorbidity. Towards personalised care for patients with Chronic Obstructive Pulmonary Disease

  2018cites this paper
• Study Profile J Epidemiol 2019 The LEAD ( Lung , Heart , Social , Body ) Study : Objectives , Methodology , and External Validity of the Population-Based Cohort Study

  2018cites this paper
• The LEAD (Lung, Heart, Social, Body) Study: Objectives, Methodology, and External Validity of the Population-Based Cohort Study

  2018cites this paper
• Precision medicine in COPD: where are we and where do we need to go?

  2018cites this paper
• Stem cell-based Lung-on-Chips: The best of both worlds?

  2018cites this paper
• Bone marrow characterization in COPD: a multi-level network analysis

  2018cites this paper
• Network modules uncover mechanisms of skeletal muscle dysfunction in COPD patients

  2018cites this paper
• Personalised medicine: are we ready?

  2017cites this paper
• Towards a global initiative for fibrosis treatment (GIFT)

  2017cites this paper
• Using omics approaches to understand pulmonary diseases

  2017cites this paper
• Predicting the future from the past

  2017cites this paper
• Network science meets respiratory medicine for OSAS phenotyping and severity prediction

  2017cites this paper
• Prioritizing chronic obstructive pulmonary disease (COPD) candidate genes in COPD-related networks

  2017cites this paper
• Chronic obstructive pulmonary disease candidate gene prioritization based on metabolic networks and functional information

  2017cites this paper
• Multi-level differential network analysis of COPD exacerbations

  2017cites this paper
• The EASI model: A first integrative computational approximation to the natural history of COPD

  2017cites this paper
• What does endotyping mean for treatment in chronic obstructive pulmonary disease?

  2017cites this paper
• Precision medicine in airway diseases: moving to clinical practice

  2017cites this paper
• A structural approach to disentangle the visualization of bipartite biological networks

  2017cites this paper
• Characterization of the pulmonary and systemic immune response in relation with lung stem cells in patients with COPD

  2017cites this paper
• Incidental detection by computed tomography is an independent prognostic factor for survival in patients operated for nonsmall cell lung carcinoma

  2017cites this paper
• Biomarkers, the control panel and personalized COPD medicine

  2016cites this paper
• Which Are The Most Relevant Comorbidities In COPD

  2016cites this paper
• Relevance of Systems Biology to Respiratory Medicine

  2016cites this paper
• Two Faces of Sarcoidosis. A Genetic Insight?

  2016cites this paper
• Treatable traits: toward precision medicine of chronic airway diseases

  2016cites this paper
• LSC 2016: from system approaches in lung disease to getting the job you want

  2016cites this paper
• Network Analysis of Lung Transcriptomics Reveals a Distinct B-Cell Signature in Emphysema.

  2016cites this paper
• Current concepts in targeting COPD pharmacotherapy: making progress towards personalized management

  2016cites this paper
• Drug development for airway diseases: looking forward

  2015cites this paper
• Current concepts in targeting chronic obstructive pulmonary disease pharmacotherapy: making progress towards personalised management.

  2015cites this paper
• Prevalência de multimorbidade na população de Florianópolis com idade igual ou superior a 40 anos: clusters e networking das morbidades

  2015cites this paper
• COPD comorbidities network

  2015cites this paper
• Network analysis: a way forward for understanding COPD multimorbidity

  2015cites this paper
• Personalized respiratory medicine: exploring the horizon, addressing the issues. Summary of a BRN-AJRCCM workshop held in Barcelona on June 12, 2014.

  2015cites this paper
• The asthma-COPD overlap syndrome: towards a revised taxonomy of chronic airways diseases?

  2015cites this paper
• Molecular and clinical diseasome of comorbidities in exacerbated COPD patients

  2015cites this paper
• Novel therapeutic strategy in the management of COPD: a systems medicine approach.

  2015cites this paper