Reduced expression of retinoblastoma (Rb) gene protein is related to cell proliferation and prognosis in transitional-cell bladder cancer

No abstract is available for this paper.

• Publication year

  2005

• Venue

  Journal of Cancer Research and Clinical Oncology

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1007/BF01202728PMID 7860618PMCID PMC12200085
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Expression of epidermal growth factor receptor in bladder cancer as related to established prognostic factors, oncoprotein (c-erbB-2, p53) expression and long-term prognosis.

  1994cited by this paper
• Aberrant RB gene expression in routinely processed, archival tumor tissues determined by three different anti‐RB antibodies

  1994cited by this paper
• p53 as an independent prognostic marker in lymph node-negative breast cancer patients.

  1993cited by this paper
• Nuclear overexpression of p53 protein in transitional cell bladder carcinoma: a marker for disease progression.

  1993cited by this paper
• Flow cytometry in comparison with mitotic index in predicting disease outcome in transitional‐cell bladder cancer

  1993influential reference
• Over‐expression of p53 nuclear oncoprotein in transitional‐cell bladder cancer and its prognostic value

  1993influential reference
• Loss of RB protein expression in primary bladder cancer correlates with loss of heterozygosity at the RB locus and tumor progression

  1993influential reference
• Expression of c-erbB-2 oncoprotein in transitional cell bladder cancer.

  1993cited by this paper
• The retinoblastoma gene: role in cell cycle control and cell differentiation

  1993cited by this paper
• Small subgroup of aggressive, highly proliferative prostatic carcinomas defined by p53 accumulation.

  1992cited by this paper
• Independent clinical, histological and quantitative prognostic factors in transitional‐cell bladder tumours, with special reference to mitotic frequency

  1992influential reference
• Expression of the retinoblastoma gene product in bladder carcinoma cells associates with a low frequency of tumor formation.

  1992cited by this paper
• Changes in growth and tumorigenicity following reconstitution of retinoblastoma gene function in various human cancer cell types by microcell transfer of chromosome 13.

  1992cited by this paper
• Altered expression of retinoblastoma protein and known prognostic variables in locally advanced bladder cancer.

  1992cited by this paper
• Over‐expression of p53 nuclear oncoprotein in colorectal adenomas

  1992cited by this paper
• Altered expression of the retinoblastoma gene product: prognostic indicator in bladder cancer.

  1992cited by this paper
• Identification of p53 gene mutations in bladder cancers and urine samples.

  1991cited by this paper
• Loss of heterozygosity at the RB locus is frequent and correlates with muscle invasion in bladder carcinoma.

  1991cited by this paper
• The retinoblastoma gene functions as a growth and tumor suppressor in human bladder carcinoma cells.

  1991cited by this paper
• Correlation between retinoblastoma gene expression and differentiation in human testicular tumors.

  1991cited by this paper
• Inactivation of the retinoblastoma gene in human bladder and renal cell carcinomas.

  1991cited by this paper
• Molecular genetics of the retinoblastoma suppressor gene.

  1991influential reference
• Growth suppression induced by wild-type p53 protein is accompanied by selective down-regulation of proliferating-cell nuclear antigen expression.

  1991influential reference
• Promoter deletion and loss of retinoblastoma gene expression in human prostate carcinoma.

  1990cited by this paper
• p53: oncogene or anti-oncogene?

  1990cited by this paper
• Suppression of human colorectal carcinoma cell growth by wild-type p53.

  1990cited by this paper
• The retinoblastoma protein is phosphorylated during specific phases of the cell cycle.

  1989cited by this paper
• Abnormalities in structure and expression of the human retinoblastoma gene in SCLC.

  1988cited by this paper
• Inactivation of the retinoblastoma susceptibility gene in human breast cancers.

  1988cited by this paper
• The retinoblastoma susceptibility gene encodes a nuclear phosphoprotein associated with DNA binding activity

  1987cited by this paper
• Human retinoblastoma susceptibility gene: cloning, identification, and sequence

  1987cited by this paper
• A chromosomal breakpoint that separates the esterase D and retinoblastoma predisposition loci in a patient with del(13)(q14q31).

  1987cited by this paper
• Evaluation of epidermal growth factor receptors in bladder tumours.

  1987cited by this paper
• A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma

  1986cited by this paper
• Localization of gene for human p53 tumour antigen to band 17p13

  1986cited by this paper
• International Histological Classification of Tumours

  1981cited by this paper
• A computer program for comparing K samples with right-censored data.

  1972cited by this paper
• transitional cell carcinoma

  year unknowncited by this paper

• A stemness-related seven-gene signature for predicting prognosis and treatment response in muscle invasive bladder cancer

  2020influential citation
• XPO1 inhibition by selinexor induces potent cytotoxicity against high grade bladder malignancies

  2018cites this paper
• Biomarkers in bladder cancer: translational and clinical implications.

  2014cites this paper
• When Is Hub Gene Selection Better than Standard Meta-Analysis?

  2013cites this paper
• Tissue‐based Biomarkers

  2012cites this paper
• Malignant transformation of mature cystic teratoma to squamous cell carcinoma involves altered expression of p53‐ and p16/Rb‐dependent cell cycle regulator proteins

  2008cites this paper
• Predictive value of p53 and pRb expression in superficial bladder cancer patients treated with BCG and interferon‐alpha

  2007cites this paper
• Novel p53/p130 axis in bladder tumors.

  2007cites this paper
• Chapter 14 – Immunohistology of the Prostate, Bladder, Testis and Kidney

  2006cites this paper
• Current concepts in the role of intravesical instillations in the therapy and prophylaxis of superficial transitional-cell cancer of the bladder

  2005cites this paper
• Expression of retinoblastoma gene (Rb) protein in T12MO prostatic adenocarcinoma

  2005cites this paper
• P53 as a prognostic marker for bladder cancer: a meta-analysis and review.

  2005cites this paper
• Immunoreactivity of bcl-2, p53 and EGFr is associated with tumor stage, grade and cell proliferation in superficial bladder cancer

  2004cites this paper
• Molecular prognostic factors in bladder cancer

  2004cites this paper
• Molecular biology of transitional cell carcinoma.

  2003cites this paper
• Retinoblastoma protein expression is an independent predictor of both radiation response and survival in muscle-invasive bladder cancer

  2003cites this paper
• Cell Cycle Inhibitors in Cancer Therapy

  2003cites this paper
• The molecular pathology of neoplastic and non-neoplastic vulval disease

  2003cites this paper
• Expression of cathepsin D in urothelial carcinoma of the urinary bladder: an immunohistochemical study including correlations with extracellular matrix components, CD44, p53, Rb, c-erbB-2 and the proliferation indices.

  2002cites this paper
• Apoptosis, proliferation and p53, cyclin D1, and retinoblastoma gene expression in relation to radiation response in transitional cell carcinoma of the bladder.

  2001cites this paper
• Molecular and kinetic features of transitional cell carcinomas of the bladder: biological and clinical implications

  2001cites this paper
• Cyclin D1 and retinoblastoma protein in vulvar cancer and adjacent lesions

  2001cites this paper
• Genetic alterations and biological pathways in human bladder cancer pathogenesis.

  2000cites this paper
• Immunohistochemical expression of retinoblastoma gene product (Rb), p53 protein, MDM2, c-erbB-2, HLA-DR and proliferation indices in human urinary bladder carcinoma.

  2000cites this paper
• [Molecular biology in bladder cancer].

  2000cites this paper
• Cell cycle regulators: mechanisms and their role in aetiology, prognosis, and treatment of cancer.

  1999cites this paper
• G1 checkpoint protein and p53 abnormalities occur in most invasive transitional cell carcinomas of the urinary bladder

  1999cites this paper
• Relationship among cystectomy, microvessel density and prognosis in stage T1 transitional cell carcinoma of the bladder.

  1998cites this paper
• p53 and RB expression predict progression in T1 bladder cancer.

  1998cites this paper
• Expression of p21(waf1/cip1) Protein in Transitional Cell Bladder Tumours and Its Prognostic Value

  1998cites this paper
• Cyclin D1 overexpression related to retinoblastoma protein expression as a prognostic marker in human oesophageal squamous cell carcinoma.

  1998cites this paper
• [Prognostic factors of infiltrating bladder tumors].

  1998cites this paper
• Molecular biological changes in bladder cancer.

  1998cites this paper
• Alterations of TP53 in microdissected transitional cell carcinoma of the human urinary bladder: high frequency of TP53 accumulation in the absence of detected mutations is associated with poor prognosis.

  1998cites this paper
• Microsatellite alterations at chromosomes 9p, 13q, and 17p in nonmuscle-invasive transitional cell carcinomas of the urinary bladder.

  1998cites this paper
• Retinoblastoma protein expression and radiation response in muscle-invasive bladder cancer.

  1997cites this paper
• Aberrant expression of p53 and retinoblastoma gene products in human esophageal squamous cell carcinoma.

  1997cites this paper
• Overexpressed cyclin D1 protein related to p53 and retinoblastoma proteins in transitional cell carcinoma of the urinary tract.

  1997cites this paper
• p53, bcl-2 and retinoblastoma proteins as long-term prognostic markers in localized carcinoma of the prostate.

  1997cites this paper
• Alterations of cell cycle regulatory genes in primary (de novo) and secondary glioblastomas

  1997cites this paper
• Retinoblastoma protein and proliferating-cell nuclear antigen expression as predictors of recurrence in well-differentiated papillary thyroid carcinoma.

  1997cites this paper
• Loss of retinoblastoma gene function and heterozygosity at the RB locus in renal cortical neoplasms.

  1997cites this paper
• The p53 gene as a modifier of intrinsic radiosensitivity: implications for radiotherapy.

  1996cites this paper
• A molecular genetic model of human bladder cancer pathogenesis.

  1996cites this paper