Chemopreventive effect of a novel oleanane triterpenoid in a chemically induced rodent model of breast cancer

No abstract is available for this paper.

• Publication year

  2013

• Venue

  International Journal of Cancer

• Publication date

  2013-09-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1002/ijc.28108PMID 23404339PMCID PMC3702660
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Hormonal Carcinogenesis

  2020cited by this paper
• Chemoprevention for Breast Cancer

  2015cited by this paper
• Prevention of rat breast cancer by genistin and selenium

  2012cited by this paper
• Modulation of angiogenesis by dietary phytoconstituents in the prevention and intervention of breast cancer.

  2012cited by this paper
• Chemoprevention for breast cancer.

  2012cited by this paper
• Chemoprevention of breast cancer by dietary compounds.

  2012cited by this paper
• Dietary supplements and natural products in breast cancer trials.

  2012cited by this paper
• Global cancer statistics

  2011cited by this paper
• CDDO-Methyl Ester Delays Breast Cancer Development in Brca1-Mutated Mice

  2011cited by this paper
• Triterpenoids as potential agents for the chemoprevention and therapy of breast cancer.

  2011cited by this paper
• Preventive therapy for breast cancer: a consensus statement.

  2011cited by this paper
• Chemoprevention of hormone receptor-negative breast cancer: new approaches needed.

  2011cited by this paper
• The chemopreventive action of equol enantiomers in a chemically induced animal model of breast cancer.

  2010cited by this paper
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  2009cited by this paper
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  2009cited by this paper
• Do cancer cells care if their host is hungry?

  2009cited by this paper
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  2009cited by this paper
• Terpenoids and breast cancer chemoprevention

  2009cited by this paper
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  2009cited by this paper
• Characterization of Breast Cancer Progression in the Rat

  2008cited by this paper
• Prevention and Treatment of Experimental Estrogen Receptor – Negative Mammary Carcinogenesis by the Synthetic Triterpenoid CDDO-Methyl Ester and the Rexinoid LG100268

  2008cited by this paper
• Novel synthetic triterpenoid methyl 25‐Hydroxy‐3‐Oxoolean‐12‐en‐28‐Oate induces apoptosis through JNK and p38 MAPK pathways in human breast adenocarcinoma MCF‐7 cells

  2008influential reference
• The novel triterpenoid C-28 methyl ester of 2-cyano-3, 12-dioxoolen-1, 9-dien-28-oic acid inhibits metastatic murine breast tumor growth through inactivation of STAT3 signaling.

  2007cited by this paper
• Short-term Modulation of Cell Proliferation and Apoptosis and Preventive/Therapeutic Efficacy of Various Agents in a Mammary Cancer Model

  2007cited by this paper
• Retention and Use of Breast Cancer Recurrence Risk Information from Genomic Tests: The Role of Health Literacy

  2007cited by this paper
• Chemoprevention of breast cancer with selective oestrogen-receptor modulators

  2007cited by this paper
• Anticancer effects of amooranin in human colon carcinoma cell line in vitro and in nude mice xenografts

  2006cited by this paper
• Novel triterpenoid 25-hydroxy-3-oxoolean-12-en-28-oic acid induces growth arrest and apoptosis in breast cancer cells

  2006cited by this paper
• Progress in Chemoprevention Drug Development: The Promise of Molecular Biomarkers for Prevention of Intraepithelial Neoplasia and Cancer—A Plan to Move Forward

  2006cited by this paper
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  2006cited by this paper
• Cytochrome P450-mediated metabolism of estrogens and its regulation in human.

  2005cited by this paper
• Timing of Exposure and Mammary Cancer Risk

  2004cited by this paper
• The novel synthetic triterpenoid, CDDO-imidazolide, inhibits inflammatory response and tumor growth in vivo.

  2003cited by this paper
• Activation of peroxisome proliferator-activated receptor gamma by a novel synthetic triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid induces growth arrest and apoptosis in breast cancer cells.

  2003cited by this paper
• Novel Drug Amooranin Induces Apoptosis Through Caspase Activity in Human Breast Carcinoma Cell Lines

  2003cited by this paper
• Novel plant triterpenoid drug amooranin overcomes multidrug resistance in human leukemia and colon carcinoma cell lines

  2003cited by this paper
• Histopathologic characterization of mammary neoplastic lesions induced with 7,12 dimethylbenz(alpha)anthracene in the rat: a comparative analysis with human breast tumors.

  2002cited by this paper
• Initiator caspases in apoptosis signaling pathways

  2002cited by this paper
• Cytotoxic activity of amooranin and its derivatives

  2002cited by this paper
• Re: Henderson,B.E. and Feigelson,H.S. (2000) hormonal carcinogenesis. Carcinogenesis, 21, 427-433.

  2001cited by this paper
• Chemoprevention of breast cancer

  2000cited by this paper
• Vanadium chemoprevention of 7,12-dimethylbenz(a)anthracene-induced rat mammary carcinogenesis: probable involvement of representative hepatic phase I and II xenobiotic metabolizing enzymes

  2000cited by this paper
• Hormonal carcinogenesis.

  2000cited by this paper
• Tamoxifen, raloxifene, and the prevention of breast cancer.

  1999cited by this paper
• ANTITUMOR ACTIVITY OF AMOORANIN FROM AMOORA ROHITUKA STEM BARK

  1996cited by this paper
• Decreased tumor formation in 7,12-dimethylbenzanthracene-treated stromelysin-1 transgenic mice is associated with alterations in mammary epithelial cell apoptosis.

  1995cited by this paper
• Fat and calories in colon and breast cancer: from animal studies to controlled clinical trials.

  1993cited by this paper
• PCNA and Ki67 expression in breast carcinoma: correlations with clinical and biological variables.

  1992cited by this paper
• Clonal adaptation during carcinogenesis.

  1990cited by this paper
• Comparative study of human and rat mammary tumorigenesis.

  1990cited by this paper
• Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

  1990cited by this paper
• Effect of diets with different protein levels on the growth of Walker 256 carcinosarcoma in rats.

  1989cited by this paper

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  2025cites this paper
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  2024cites this paper
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  2024cites this paper
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  2024cites this paper
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  2023cites this paper
• Oleanolic acid increases the anticancer potency of doxorubicin in pancreatic cancer cells

  2023cites this paper
• Zingiberene exerts chemopreventive activity against 7,12‐dimethylbenz(a)anthracene‐induced breast cancer in Sprague‐Dawley rats

  2022cites this paper
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  2022cites this paper
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  2022cites this paper
• Natural Compounds in Sex Hormone-Dependent Cancers: The Role of Triterpenes as Therapeutic Agents

  2021cites this paper
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  2021cites this paper
• Targeting the crosstalk between canonical Wnt/β-catenin and inflammatory signaling cascades: A novel strategy for cancer prevention and therapy.

  2021cites this paper
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  2021cites this paper
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  2020cites this paper
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  2020cites this paper
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  2019cites this paper
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  2018cites this paper
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  2018cites this paper
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  2018cites this paper
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  2017cites this paper
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  2017cites this paper
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  2017cites this paper
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  2017cites this paper
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  2016cites this paper
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  2016cites this paper
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  2016cites this paper
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  2016cites this paper
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  2016cites this paper
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  2015cites this paper
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  2015cites this paper
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  2015cites this paper
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  2015cites this paper
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  2015cites this paper
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  2015cites this paper
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  2015cites this paper
• Oleanane triterpenoids in the prevention and therapy of breast cancer: current evidence and future perspectives

  2014influential citation
• Oleanolic acid and its synthetic derivatives for the prevention and therapy of cancer: preclinical and clinical evidence.

  2014cites this paper
• Suppression of inflammatory cascade is implicated in methyl amooranin‐mediated inhibition of experimental mammary carcinogenesis

  2014influential citation
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  2014cites this paper
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  2013influential citation