Atypical Regulation of Hepatic Adenylyl Cyclase and Adrenergic Receptors During a Critical Developmental Period: Agonists Evoke Supersensitivity Accompanied by Failure of Receptor Down-Regulation

No abstract is available for this paper.

• Publication year

  1996

• Venue

  Pediatric Research

• Publication date

  1996-04-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1203/00006450-199604000-00023PMID 8848348
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• fl-Adrenoceptor control of cardiac adenylyl cyclase during development : agonist pretreatment in the neonate uniquely causes heterologous sensitization , not desensitization

  2003cited by this paper
• Role of presynaptic input in the ontogeny of adrenergic cell signaling in rat brain: beta receptors, adenylate cyclase and c-fos protooncogene expression.

  1995cited by this paper
• Reduced beta-adrenergic receptor activation decreases G-protein expression and beta-adrenergic receptor kinase activity in porcine heart.

  1995cited by this paper
• Neural input and the development of adrenergic intracellular signaling: neonatal denervation evokes neither receptor upregulation nor persistent supersensitivity of adenylate cyclase.

  1995cited by this paper
• Postnatal development of ornithine decarboxylase and polyamines in the mouse kidney: influence of testosterone.

  1994cited by this paper
• Glucocorticoids enhance intracellular signaling via adenylate cyclase at three distinct loci in the fetus: a mechanism for heterologous teratogenic sensitization?

  1994cited by this paper
• Receptor crosstalk: effects of prolonged carbachol exposure on β1-adrenoceptors and adenylyl cyclase activity in neonatal rat ventricular myocytes

  1994cited by this paper
• Norepinephrine utilizes alpha 1- and beta-adrenoreceptors synergistically to maximally induce c-fos expression in brown adipocytes.

  1994cited by this paper
• Role of thyroid status in the ontogeny of adrenergic cell signaling in rat brain: beta receptors, adenylate cyclase, ornithine decarboxylase and c-fos protooncogene expression.

  1994cited by this paper
• Glucocorticoid regulation of G-protein subunits in neonatal liver.

  1993cited by this paper
• Glucocorticoids regulate the development of intracellular signaling: enhanced forebrain adenylate cyclase catalytic subunit activity after fetal dexamethasone exposure.

  1993cited by this paper
• Promotional role for glucocorticoids in the development of intracellular signalling: enhanced cardiac and renal adenylate cyclase reactivity to beta-adrenergic and non-adrenergic stimuli after low-dose fetal dexamethasone exposure.

  1992cited by this paper
• Lowered responsiveness of the catalyst of adenylyl cyclase to stimulation by GS in heterologous desensitization: a role for adenosine 3',5'-monophosphate-dependent phosphorylation.

  1992cited by this paper
• Effects of thyroid hormone on myocardial adrenergic beta-receptor responsiveness and function during late gestation.

  1992cited by this paper
• Promotional role for glucocorticoids in the development of intracellular signalling: enhanced cardiac and renal adenylate cyclase reactivity to beta-adrenergic and non-adrenergic stimuli after low-dose fetal dexamethasone exposure.

  1992cited by this paper
• Effects of Thyroid Hormone on Myocardial Adrenergic β-Receptor Responsiveness and Function during Late Gestation

  1992cited by this paper
• Adrenergic regulation of neonatal brown fat adenylyl cyclase and Gs alpha activity.

  1992cited by this paper
• Developmental changes in adenylyl cyclase and GTP binding proteins in brown fat.

  1991cited by this paper
• Presynaptic input regulates development of beta-adrenergic control of rat brain ornithine decarboxylase: effects of 6-hydroxydopamine or propranolol.

  1991cited by this paper
• Thyroid hormone differentially regulates development of beta-adrenergic receptors, adenylate cyclase and ornithine decarboxylase in rat heart and kidney.

  1991cited by this paper
• Role of serotonin and other neurotransmitter receptors in brain development: basis for developmental pharmacology.

  1991cited by this paper
• Glucocorticoids regulate the ontogenetic transition of adrenergic receptor subtypes in rat liver.

  1991cited by this paper
• Control of adenylate cyclase activity in developing rat heart and liver: effects of prenatal exposure to terbutaline or dexamethasone.

  1991cited by this paper
• Fetal nicotine exposure produces postnatal up-regulation of adenylate cyclase activity in peripheral tissues.

  1990cited by this paper
• Phosphatidic acid phosphatase in neonatal rat lung: effects of prenatal dexamethasone or terbutaline treatment on basal activity and on responsiveness to beta adrenergic stimulation.

  1989cited by this paper
• Role of sympathetic neurons in development of beta-adrenergic control of ornithine decarboxylase activity in peripheral tissues: effects of neonatal 6-hydroxydopamine treatment.

  1989cited by this paper
• Neonatal sympathectomy compromises development of responses of ornithine decarboxylase to hormonal stimulation in peripheral tissues.

  1989cited by this paper
• Ontogeny of fetal adenylate cyclase; mechanisms for regulation of beta-adrenergic receptors.

  1989cited by this paper
• Reduction in the stability of the Gs-catalytic unit complex of adenylate cyclase in isoproterenol-induced heterologous desensitization.

  1989cited by this paper
• Glycogenolytic responsiveness to glucagon, epinephrine, vasopressin and angiotensin II in the liver of developing hypothyroid rats. A comparative study of in vitro hormonal binding and in vivo biological response.

  1989cited by this paper
• Development of the linkage of beta-adrenergic receptors to cardiac hypertrophy and heart rate control: neonatal sympathectomy with 6-hydroxydopamine.

  1989cited by this paper
• Identification of a specific site required for rapid heterologous desensitization of the beta-adrenergic receptor by cAMP-dependent protein kinase.

  1989cited by this paper
• Mechanisms of Receptor Activation in Adenylate Cyclase Systems

  1989cited by this paper
• Alpha 1-adrenergic receptor subtypes, inositol phosphates, and sources of cell Ca2+.

  1988cited by this paper
• Adrenomedullary catecholamine release in the fetus and newborn: secretory mechanisms and their role in stress and survival.

  1988cited by this paper
• Post-natal evolution of rat cardiac beta-adrenoceptors.

  1988cited by this paper
• Receptor activation of G proteins

  1988cited by this paper
• Life cycles of cardiac alpha 1- and beta-adrenergic receptors.

  1987cited by this paper
• Life cycles of cardiac α1- and β-adrenergic receptors

  1987cited by this paper
• Forskolin: its biological and chemical properties.

  1986cited by this paper
• The "stress" of being born.

  1986cited by this paper
• Effects of chemical sympathectomy with 6-hydroxydopamine on alpha- and beta-adrenoceptors and muscarinic cholinoceptors in rat kidney.

  1986cited by this paper
• Development of gluconeogenesis from different substrates in newborn rabbit hepatocytes.

  1986cited by this paper
• Effects of chemical sympathectomy with 6-hydroxydopamine on α- and β-adrenoceptors and muscarinic cholinoceptors in rat kidney

  1986cited by this paper
• Effect of adenosine 3',5'-cyclic monophosphate on volume and cytoskeleton of MDCK cells.

  1986cited by this paper
• Effects of neonatal methylmercury exposure on adrenergic receptor binding sites in peripheral tissues of the developing rat.

  1986cited by this paper
• Mechanisms of adrenergic control of blood pressure in developing rats.

  1986cited by this paper
• Ontogeny of rat hepatic adrenoceptors.

  1983cited by this paper
• Age-related changes in the control of hepatic cyclic AMP levels by alpha 1- and beta 2-adrenergic receptors in male rats.

  1983cited by this paper
• Prenatal psychotropic drug exposure and the development of central dopaminergic and cholinergic neurotransmitter systems.

  1983cited by this paper
• Maturation of sympathetic neurotransmission in the rat heart. IX. Development of transsynaptic regulation of cardiac adrenergic sensitivity.

  1982cited by this paper
• Development of sympathetic ganglionic neurotransmission in the neonatal rat. Pre- and postganglionic nerve response to asphyxia and 2-deoxyglucose.

  1982cited by this paper
• Beta-adrenergic receptor subtypes: properties, distribution, and regulation.

  1981cited by this paper
• Development of central control of norepinephrine turnover and release in the rat heart: responses to tyramine, 2-deoxyglucose and hydralazine.

  1981cited by this paper
• Activation of adenylate cyclase by the diterpene forskolin does not require the guanine nucleotide regulatory protein.

  1981cited by this paper
• Alterations in cardiac autonomic receptors following 6-hydroxydopamine treatment in rats.

  1980cited by this paper
• PRESYNAPTIC AND POSTSYNAPTIC CONTRIBUTIONS TO ONTOGENY OF SYMPATHETIC CONTROL OF HEART RATE IN THE PRE‐WEANLING RAT

  1979cited by this paper
• Alpha- and beta-adrenergic receptors of the rat salivary gland. Elevation after chemical sympathectomy.

  1979cited by this paper
• Effects of thyroid deficiency and sympathectomy on cardiac enzymes.

  1979cited by this paper
• Autonomic neural control of liver glycogen metabolism.

  1979cited by this paper
• Catecholamine Release in the Newborn Infant at Birth

  1977cited by this paper
• Protein measurement with the Folin phenol reagent.

  1951cited by this paper

• Developmental DSP4 effects on cortical Arc expression.

  2016cites this paper
• TERBUTALINE IMPAIRS THE DEVELOPMENT OF PERIPHERAL NORADRENERGIC PROJECTIONS: IMPLICATIONS FOR AUTISM SPECTRUM DISORDERS AND PHARMACOTHERAPY OF PRETERM LABOR

  2013cites this paper
• Terbutaline impairs the development of peripheral noradrenergic projections: potential implications for autism spectrum disorders and pharmacotherapy of preterm labor.

  2013cites this paper
• Moderate Global Reduction in Maternal Nutrition Has Differential Stage of Gestation Specific Effects on β1- and β2-Adrenergic Receptors in the Fetal Baboon Liver

  2011cites this paper
• Oxidative stress from diverse developmental neurotoxicants: antioxidants protect against lipid peroxidation without preventing cell loss.

  2010cites this paper
• Developmental Neurotoxicity of Perfluorinated Chemicals Modeled in Vitro

  2008cites this paper
• Screening for Developmental Neurotoxicity Using PC12 Cells: Comparisons of Organophosphates with a Carbamate, an Organochlorine, and Divalent Nickel

  2006cites this paper
• Adverse Neurodevelopmental Effects of Dexamethasone Modeled in PC12 Cells: Identifying the Critical Stages and Concentration Thresholds for the Targeting of Cell Acquisition, Differentiation and Viability

  2006cites this paper
• Modeling the developmental neurotoxicity of nicotine in vitro: cell acquisition, growth and viability in PC12 cells.

  2005cites this paper
• Effects of Prenatal Nicotine Exposure on Primate Brain Development and Attempted Amelioration with Supplemental Choline or Vitamin C: Neurotransmitter Receptors, Cell Signaling and Cell Development Biomarkers in Fetal Brain Regions of Rhesus Monkeys

  2005cites this paper
• Long-lasting CNS effects of a short-term chemical knockout of ornithine decarboxylase during development: nicotinic cholinergic receptor upregulation and subtle macromolecular changes in adulthood.

  2003cites this paper
• Fetal chlorpyrifos exposure: adverse effects on brain cell development and cholinergic biomarkers emerge postnatally and continue into adolescence and adulthood.

  2002cites this paper
• Are developing beta-adrenoceptors able to desensitize? Acute and chronic effects of beta-agonists in neonatal heart and liver.

  2002cites this paper
• Neonatal Models and Ventilatory Behavior

  2002cites this paper
• Are developing β-adrenoceptors able to desensitize? Acute and chronic effects of β-agonists in neonatal heart and liver

  2002influential citation
• Beta-adrenoceptor control of G protein function in the neonate: determinant of desensitization or sensitization.

  2002cites this paper
• Beta-adrenoceptor-mediated cell signaling in the neonatal heart and liver: responses to terbutaline.

  2001cites this paper
• β-adrenoceptor signaling and its control of cell replication in MDA-MB-231 human breast cancer cells

  2000cites this paper
• Beta-adrenoceptor signaling and its control of cell replication in MDA-MB-231 human breast cancer cells.

  2000cites this paper
• Ontogeny of cardiac beta-adrenoceptor desensitization mechanisms: agonist treatment enhances receptor/G-protein transduction rather than eliciting uncoupling.

  1999cites this paper
• Beta-adrenergic stimulation of cellular K+ uptake in rat distal colon.

  1998cites this paper
• Ontogeny of regulatory mechanisms for beta-adrenoceptor control of rat cardiac adenylyl cyclase: targeting of G-proteins and the cyclase catalytic subunit.

  1997cites this paper
• Ontogeny of β-adrenoceptor/adenylyl cyclase desensitization mechanisms: the role of neonatal innervation

  1996cites this paper