Disease progression in macaques with low SIV replication levels: on the relevance of TREC counts

No abstract is available for this paper.

• Publication year

  2005

• Venue

  AIDS (London)

• Publication date

  2005-04-29

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1097/01.aids.0000166089.93574.5aPMID 15821392
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Thymic volume is associated independently with the magnitude of short‐ and long‐term repopulation of CD4+ T cells in HIV‐infected adults after highly active antiretroviral therapy (HAART) 1

  2004influential reference
• Differences in disease progression in a cohort of long-term non-progressors after more than 16 years of HIV-1 infection

  2004cited by this paper
• IL-7 Stimulates T Cell Renewal Without Increasing Viral Replication in Simian Immunodeficiency Virus-Infected Macaques 1

  2003cited by this paper
• Immunological and virological failure after antiretroviral therapy is associated with enhanced peripheral and thymic pathogenicity.

  2003cited by this paper
• Mitochondria in HIV-1-induced apoptosis.

  2003cited by this paper
• Live attenuated, nef-deleted SIV is pathogenic in most adult macaques after prolonged observation

  2003cited by this paper
• SIVagm: genetic and biological features associated with replication.

  2003cited by this paper
• Distinct Cycling CD4+- and CD8+-T-Cell Profiles during the Asymptomatic Phase of Simian Immunodeficiency Virus SIVmac251 Infection in Rhesus Macaques

  2003cited by this paper
• A Truncated Form of Nef Selected during Pathogenic Reversion of Simian Immunodeficiency Virus SIVmac239Δnef Increases Viral Replication

  2003cited by this paper
• Phenotypic and functional T-cell aging in rhesus macaques (Macaca mulatta): differential behavior of CD4 and CD8 subsets.

  2003cited by this paper
• Extensive apoptosis in lymphoid organs during primary SIV infection predicts rapid progression towards AIDS

  2003cited by this paper
• Phenotypic and functional T-cell aging in rhesus macaques ( Macaca mulatta ) : differential behavior of CD 4 and CD 8 subsets

  2003cited by this paper
• T cells containing T cell receptor excision circles are inversely related to HIV replication and are selectively and rapidly released into circulation with antiretroviral treatment

  2003cited by this paper
• Caspase-dependent and -independent T-cell death pathways in pathogenic simian immunodeficiency virus infection: relationship to disease progression

  2003cited by this paper
• Subpopulations of long-lived and short-lived T cells in advanced HIV-1 infection.

  2003cited by this paper
• Thymic output: a bad TREC record

  2003cited by this paper
• Longitudinal follow up of SIVmac pathogenesis in rhesus macaques of Chinese origin: emergence of B cell lymphoma

  2002cited by this paper
• IFN-α Secretion by Type 2 Predendritic Cells Up-Regulates MHC Class I in the HIV-1-Infected Thymus1

  2002cited by this paper
• Decreased Levels of Recent Thymic Emigrants in Peripheral Blood of Simian Immunodeficiency Virus-Infected Macaques Correlate with Alterations within the Thymus

  2002cited by this paper
• Changes in blood chemistry and hematology variables during aging in captive rhesus macaques (Macaca mulatta)

  2001cited by this paper
• Persistence of Pathogenic Challenge Virus in Macaques Protected by Simian Immunodeficiency Virus SIVmacΔnef

  2001cited by this paper
• Poor CD4 T cell restoration after suppression of HIV-1 replication may reflect lower thymic function

  2001influential reference
• Evidence for Increased T Cell Turnover and Decreased Thymic Output in HIV Infection1

  2001cited by this paper
• Thymopoiesis in HIV-Infected Adults after Highly Active Antiretroviral Therapy

  2001cited by this paper
• Effect of recent thymic emigrants on progression of HIV-1 disease.

  2000influential reference
• Pathogenic Conversion of Live Attenuated Simian Immunodeficiency Virus Vaccines Is Associated with Expression of Truncated Nef

  2000cited by this paper
• Live Attenuated HIV Vaccines: A Proposal for Further Research and Development

  2000cited by this paper
• Sensitive and Robust One-Tube Real-Time Reverse Transcriptase-Polymerase Chain Reaction to Quantify SIV RNA Load: Comparison of One- versus Two-Enzyme Systems

  2000cited by this paper
• Early changes in peripheral blood T cells during primary infection of rhesus macaques with a pathogenic SIV

  2000cited by this paper
• Functional and Structural Defects in HIV Type 1 nef Genes Derived from Pediatric Long-Term Survivors

  2000cited by this paper
• CD4+Ki67+ lymphocytes in HIV‐infected patients are effector T cells accumulated in the G1 phase of the cell cycle

  2000cited by this paper
• Characterization of Three nef-Defective Human Immunodeficiency Virus Type 1 Strains Associated with Long-Term Nonprogression

  2000cited by this paper
• Initial increase in blood CD4(+) lymphocytes after HIV antiretroviral therapy reflects redistribution from lymphoid tissues.

  1999cited by this paper
• Measuring Recent Thymic Emigrants in Blood of Normal and HIV-1–Infected Individuals before and after Effective Therapy

  1999influential reference
• Thymocyte-Thymic Epithelial Cell Interaction Leads to High-Level Replication of Human Immunodeficiency Virus Exclusively in Mature CD4+ CD8− CD3+ Thymocytes: a Critical Role for Tumor Necrosis Factor and Interleukin-7

  1999cited by this paper
• Thymus volume correlates with the progression of vertical HIV infection.

  1999cited by this paper
• Immunologic and virologic status after 14 to 18 years of infection with an attenuated strain of HIV-1. A report from the Sydney Blood Bank Cohort.

  1999cited by this paper
• Declining CD4 T-cell counts in a person infected with nef-deleted HIV-1.

  1999cited by this paper
• Live attenuated, multiply deleted simian immunodeficiency virus causes AIDS in infant and adult macaques

  1999cited by this paper
• A novel mechanism of CD4 lymphocyte depletion involves effects of HIV on resting lymphocytes: induction of lymph node homing and apoptosis upon secondary signaling through homing receptors.

  1999cited by this paper
• Biphasic kinetics of peripheral blood T cells after triple combination therapy in HIV-1 infection: A composite of redistribution and proliferation

  1998cited by this paper
• High prevalence of thymic tissue in adults with human immunodeficiency virus-1 infection.

  1998cited by this paper
• Changes in thymic function with age and during the treatment of HIV infection

  1998influential reference
• Grossly Defective nef Gene Sequences in a Human Immunodeficiency Virus Type 1-Seropositive Long-Term Nonprogressor

  1998cited by this paper
• Early Regeneration of Thymic Progenitors in Rhesus Macaques Infected with Simian Immunodeficiency Virus

  1998cited by this paper
• T cell turnover in HIV-1 disease.

  1997cited by this paper
• Positive effects of combined antiretroviral therapy on CD4+ T cell homeostasis and function in advanced HIV disease.

  1997cited by this paper
• Early progression of disease in HIV-infected infants with thymus dysfunction.

  1996cited by this paper
• Fas-mediated apoptosis of CD4+ and CD8+ T cells from human immunodeficiency virus-infected persons: differential in vitro preventive effect of cytokines and protease antagonists.

  1996cited by this paper
• Limited viral spread and rapid immune response in lymph nodes of macaques inoculated with attenuated simian immunodeficiency virus.

  1995cited by this paper
• Absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection

  1995cited by this paper
• Brief report: absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection.

  1995cited by this paper
• Pathogenicity of live, attenuated SIV after mucosal infection of neonatal macaques.

  1995cited by this paper
• Pathogenic diversity of simian immunodeficiency viruses.

  1994cited by this paper
• Programmed cell death and AIDS: significance of T-cell apoptosis in pathogenic and nonpathogenic primate lentiviral infections.

  1994cited by this paper
• T-cell-mediated immunopathology versus direct cytolysis by virus: implications for HIV and AIDS.

  1994cited by this paper
• Long-term symptomless HIV-1 infection in recipients of blood products from a single donor.

  1992cited by this paper
• Protection against SIV infection in macaques by immunization with inactivated virus from the BK28 molecular clone, but not with BK28-derived recombinant env and gag proteins.

  1992cited by this paper
• Importance of the nef gene for maintenance of high virus loads and for development of AIDS.

  1991cited by this paper
• Cell dysfunction and depletion in AIDS: the programmed cell death hypothesis.

  1991cited by this paper
• Envelope glycoprotein of HIV induces interference and cytolysis resistance in CD4+ cells: mechanism for persistence in AIDS.

  1988cited by this paper
• A major mechanism of human immunodeficiency virus-induced cell killing does not involve cell fusion

  1987cited by this paper
• Sequence of simian immunodeficiency virus from macaque and its relationship to other human and simian retroviruses

  1987cited by this paper
• Fusion as a mediator of cytolysis in mixtures of uninfected CD4+ lymphocytes and cells infected by human immunodeficiency virus.

  1987cited by this paper
• AIDS retrovirus induced cytopathology: giant cell formation and involvement of CD4 antigen.

  1986cited by this paper
• Role of the HTLV-III/LAV envelope in syncytium formation and cytopathicity

  1986cited by this paper
• Isolation of T-cell tropic HTLV-III-like retrovirus from macaques.

  1985cited by this paper

• Immune Alterations and Viral Reservoir Atlas in SIV-Infected Chinese Rhesus Macaques

  2025cites this paper
• Human T-Cell Development and Thymic Egress: An Infectious Disease Perspective.

  2015cites this paper
• Dynamique d'infection des sous-populations lymphocytaires T CD4 chez le macaque Rhésus infecté par le Virus de l'Immunodéficience Simienne

  2015cites this paper
• The Different Modes of Resistance to AIDS

  2014cites this paper
• SIV infection of rhesus macaques of Chinese origin: a suitable model for HIV infection in humans

  2013cites this paper
• DRAM Triggers Lysosomal Membrane Permeabilization and Cell Death in CD4+ T Cells Infected with HIV

  2013cites this paper
• AIDS and HIV Infection after Thirty Years

  2013cites this paper
• Different Immunological Phenotypes Associated with Preserved CD4+ T Cell Counts in HIV-Infected Controllers and Viremic Long Term Non-Progressors

  2013cites this paper
• Thirty Years with HIV Infection—Nonprogression Is Still Puzzling: Lessons to Be Learned from Controllers and Long-Term Nonprogressors

  2012cites this paper
• T cell kinetics in HIV infected children

  2011cites this paper
• Factors Contributing to HIV-1 Induced Pathogenesis in the Human Thymus

  2011influential citation
• Signal Joint T-Cell Receptor Excision Circle Assay in Miniature Swine

  2011cites this paper
• Association of Progressive CD4+ T Cell Decline in SIV Infection with the Induction of Autoreactive Antibodies

  2009cites this paper
• Transient Nature of Long-Term Nonprogression and Broad Virus-Specific Proliferative T-Cell Responses with Sustained Thymic Output in HIV-1 Controllers

  2009cites this paper
• Increased neutrophil apoptosis in chronically SIV-infected macaques

  2009cites this paper
• The role of the thymus in HIV infection: a 10 year perspective

  2008cites this paper
• Human Immunodeficiency Virus Persistence and Production in T-Cell Development

  2006cites this paper
• HIV and the hidden face of the thymus.

  2006cites this paper
• IL-7 Induces Immunological Improvement in SIV-Infected Rhesus Macaques under Antiviral Therapy1

  2006cites this paper
• Techniques for measuring regional body fat: computed tomography may be suitable for evaluation of facial lipoatrophy.

  2006cites this paper
• Death of CD4+ T Cells from Lymph Nodes during Primary SIVmac251 Infection Predicts the Rate of AIDS Progression1

  2006cites this paper
• Long Lasting Control and Lack of Pathogenicity of the Attenuated Rev-Independent SIV in Rhesus Macaques

  2006cites this paper
• SIV-Infected Rhesus Macaques under IL-7 Induces Immunological Improvement in Rémi Cheynier and

  2005cites this paper