Detection of DNA cleavage in apoptotic cells.

No abstract is available for this paper.

• Publication year

  2000

• Venue

  Methods in Enzymology

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1016/S0076-6879(00)22003-XPMID 10914000
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  1950cited by this paper
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