Soluble TRAIL is present at high concentrations in seminal plasma and promotes spermatozoa survival.

No abstract is available for this paper.

• Publication year

  2014

• Venue

  Reproduction

• Publication date

  2014-08-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1530/REP-14-0144PMID 24825910
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Characterization of the Role of Tumor Necrosis Factor Apoptosis Inducing Ligand (TRAIL) in Spermatogenesis through the Evaluation of Trail Gene-Deficient Mice

  2014cited by this paper
• Death receptor-ligand systems in cancer, cell death, and inflammation.

  2013cited by this paper
• Progesterone utilizes the PI3K-AKT pathway in human spermatozoa to regulate motility and hyperactivation but not acrosome reaction.

  2013cited by this paper
• TRAIL (TNF-related apoptosis-inducing ligand) regulates adipocyte metabolism by caspase-mediated cleavage of PPARgamma

  2013influential reference
• C-Reactive Protein Downregulates TRAIL Expression in Human Peripheral Monocytes via an Egr-1–Dependent Pathway

  2013cited by this paper
• Treatment of arthritis by macrophage depletion and immunomodulation: testing an apoptosis-mediated therapy in a humanized death receptor mouse model.

  2012influential reference
• Decreased Spermatogenesis, Fertility, and Altered Slc2A Expression in Akt1−/− and Akt2−/− Testes and Sperm

  2012cited by this paper
• Seminal Fluid Induces Leukocyte Recruitment and Cytokine and Chemokine mRNA Expression in the Human Cervix after Coitus

  2012cited by this paper
• TRAIL as biomarker and potential therapeutic tool for cardiovascular diseases.

  2012cited by this paper
• N-acetyl-l-cysteine modulates multiple signaling pathways to rescue male germ cells from apoptosis induced by chronic hCG administration to rats

  2012cited by this paper
• Sertoli-secreted FGF-2 induces PFKFB4 isozyme expression in mouse spermatogenic cells by activation of the MEK/ERK/CREB pathway.

  2012cited by this paper
• Epigallocatechin gallate affects survival and metabolism of human sperm.

  2012cited by this paper
• TRAIL administration down-modulated the acute systemic inflammatory response induced in a mouse model by muramyldipeptide or lipopolysaccharide.

  2012influential reference
• Melatonin protects human spermatozoa from apoptosis via melatonin receptor- and extracellular signal-regulated kinase-mediated pathways.

  2011cited by this paper
• Association of tumor necrosis factor-related apoptosis-inducing ligand with total and cardiovascular mortality in older adults.

  2011cited by this paper
• Melatonin protects human spermatozoa from apoptosis via melatonin receptor- and extracellular signal-regulated kinase-mediated pathways.

  2011cited by this paper
• The pentose phosphate pathway plays an essential role in supporting human sperm capacitation.

  2010cited by this paper
• An imbalanced OPG/TRAIL ratio is associated to severe acute myocardial infarction.

  2010cited by this paper
• Puma and Trail/Dr5 Pathways Control Radiation-Induced Apoptosis in Distinct Populations of Testicular Progenitors

  2010cited by this paper
• Extracellular Signal-Regulated Kinases (ERKs) Pathway and Reactive Oxygen Species Regulate Tyrosine Phosphorylation in Capacitating Boar Spermatozoa1

  2010cited by this paper
• Activating T regulatory cells for tolerance in early pregnancy - the contribution of seminal fluid.

  2009cited by this paper
• Potential Prognostic Significance of Decreased Serum Levels of TRAIL after Acute Myocardial Infarction

  2009cited by this paper
• Role of full-length osteoprotegerin in tumor cell biology

  2009cited by this paper
• Tumor Necrosis Factor‐Related Apoptosis‐Inducing Ligand Promotes Migration of Human Bone Marrow Multipotent Stromal Cells

  2008influential reference
• Cross-talk between the Akt and NF-kappaB signaling pathways inhibits MEHP-induced germ cell apoptosis.

  2008cited by this paper
• Tumor necrosis factor-related apoptosis-inducing ligand and the regulation of hematopoiesis

  2008cited by this paper
• TRAIL inhibits osteoclastic differentiation by counteracting RANKL‐dependent p27Kip1 accumulation in pre‐osteoclast precursors

  2008cited by this paper
• Role for tumor necrosis factor alpha (TNF-alpha) and interleukin 1-beta (IL-1beta) determination in seminal plasma during infertility investigation.

  2007cited by this paper
• Osteoprotegerin increases leukocyte adhesion to endothelial cells both in vitro and in vivo.

  2007cited by this paper
• Role for tumor necrosis factor alpha (TNF-α) and interleukin 1-beta (IL-1β) determination in seminal plasma during infertility investigation

  2007cited by this paper
• Involvement of TRAIL/TRAIL‐receptors in human intestinal cell differentiation

  2006cited by this paper
• PI‐3K/Akt and NF‐κB/IκBα pathways are activated in Jurkat T cells in response to TRAIL treatment

  2005cited by this paper
• PI-3K/Akt and NF-kappaB/IkappaBalpha pathways are activated in Jurkat T cells in response to TRAIL treatment.

  2005cited by this paper
• Characterization of tumour necrosis factor-alpha-related apoptosis-inducing ligand and its receptors in the adult human testis.

  2004cited by this paper
• Emerging non‐apoptotic functions of tumor necrosis factor‐related apoptosis‐inducing ligand (TRAIL)/Apo2L

  2004cited by this paper
• Osteoprotegerin (OPG) acts as an endogenous decoy receptor in tumour necrosis factor‐related apoptosis‐inducing ligand (TRAIL)‐mediated apoptosis of fibroblast‐like synovial cells

  2004cited by this paper
• Evaluation of the one-step eosin-nigrosin staining technique for human sperm vitality assessment.

  2003cited by this paper
• Tumour necrosis factor‐related apoptosis‐inducing ligand sequentially activates pro‐survival and pro‐apoptotic pathways in SK‐N‐MC neuronal cells

  2003cited by this paper
• Activation of the nitric oxide synthase pathway represents a key component of tumor necrosis factor-related apoptosis-inducing ligand-mediated cytotoxicity on hematologic malignancies.

  2001influential reference
• Quality assessment of computer‐assisted semen analysis (CASA) in the andrology laboratory

  1999cited by this paper
• Osteoprotegerin Is a Receptor for the Cytotoxic Ligand TRAIL*

  1998cited by this paper
• IMP dehydrogenase inhibitor, tiazofurin, induces apoptosis in K562 human erythroleukemia cells.

  1997cited by this paper
• An autocrine loop of HIV type-1 Tat protein responsible for the improved survival/proliferation capacity of permanently Tat-transfected cells and required for optimal HIV-1 LTR transactivating activity.

  1995cited by this paper
• Uninfected haematopoietic progenitor (CD34+) cells purified from the bone marrow of AIDS patients are committed to apoptotic cell death in culture

  1993cited by this paper

• Exploring the dynamic role of circulating soluble tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) as a diagnostic and prognostic marker; a review.

  2025cites this paper
• Investigating the impact of paternal aging on murine sperm miRNA profiles and their potential link to autism spectrum disorder

  2023cites this paper
• Title: Unveiling the intricacies: Investigating the impact of paternal aging on murine sperm miRNA profiles and their potential link to autism spectrum disorder

  2023cites this paper
• Dexamethasone induces pancreatic β-cell apoptosis through upregulation of TRAIL death receptor.

  2021cites this paper
• TRAIL receptor signaling: From the basics of canonical signal transduction toward its entanglement with ER stress and the unfolded protein response.

  2020cites this paper
• Chapter 2 TRAIL-R 3 / R 4 and Inhibition of TRAIL Signalling in Cancer

  2020cites this paper
• Transcriptomic analysis of reproductive damage in the epididymis of male Kunming mice induced by chronic infection of Toxoplasma gondii PRU strain

  2019cites this paper
• Flow cytometry in Spermatology: A bright future ahead.

  2017cites this paper
• TRAIL-R3/R4 and Inhibition of TRAIL Signalling in Cancer

  2017cites this paper
• The Functions—or Not—of Seminal Plasma?

  2015cites this paper