Cellular characteristics of peripheral blood lymphocytes and tumour-infiltrating lymphocytes in patients with gynaecological tumours

No abstract is available for this paper.

• Publication year

  1997

• Venue

  Cancer Immunology and Immunotherapy

• Publication date

  1997-04-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1007/s002620050360PMID 9177470PMCID PMC11037785
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• T‐cell‐receptor engagement and tumor ICAM‐1 up‐regulation are required to by‐pass low susceptibility of melanoma cells to autologous CTL‐mediated lysis

  2009cited by this paper
• CD4+ T lymphocytes infiltrating human breast cancer recognise autologous tumor in an MHC-class-II restricted fashion

  2005cited by this paper
• Lymphokine production by human melanoma tumor-infiltrating lymphocytes

  2005cited by this paper
• In search of specific cytotoxic T lymphocytes infiltrating or accompanying human ovarian carcinoma

  2005cited by this paper
• High expression of adhesion molecules/activation markers with little interleukin-2, interferon γ, and tumor necrosis factor β gene activation in fresh tumor-infiltrating lymphocytes from lung adenocarcinoma

  2005cited by this paper
• Long-term serum/plasma-free culture of human cytotoxic T lymphocytes induced from peripheral blood mononuclear cells

  2005cited by this paper
• Growth of tumor‐infiltrating lymphocytes from human solid cancers: Summary of a 5‐year experience

  1996cited by this paper
• Role of cytokines in development of Th1 and Th2 cells.

  1996cited by this paper
• Growth of tumor-infiltrating lymphocytes from human solid cancers: summary of a 5-year experience.

  1996cited by this paper
• Predominance of a type 2 intratumoural immune response in fresh tumour‐infiltrating lymphocytes from human gliomas

  1996cited by this paper
• The role of CD4+ tumor-infiltrating lymphocytes in human solid tumors

  1995influential reference
• Induction of human autologous cytotoxic T lymphocytes on formalin-fixed and paraffin-embedded tumour sections

  1995cited by this paper
• T lymphocytes infiltrating sites of tumor rejection and progression display identical V beta usage but different cytotoxic activities.

  1995cited by this paper
• Generation of tumor-specific CTLs from melanoma patients by using peripheral blood stimulated with allogeneic melanoma tumor cell lines. Fine specificity and MART-1 melanoma antigen recognition.

  1995influential reference
• CD80 (B7) and CD86 (B70) provide similar costimulatory signals for T cell proliferation, cytokine production, and generation of CTL.

  1995cited by this paper
• Lymphocytes infiltrating colorectal cancer have low proliferative capacity but can secrete normal levels of interferon γ

  1995cited by this paper
• Immunoregulatory effects of CD4+ T helper subsets in human melanoma.

  1995cited by this paper
• Generation of CD4+ cytotoxic T lymphocytes stimulated by immobilized anti‐CD3 monoclonal antibody and interleukin‐2 in cancer patients

  1995influential reference
• Characterization of factors regulating successful immunotherapy using a tumor‐specific cytotoxic T lymphocyte clone: Role of interleukin‐2, cycling pattern of lytic activity and adhesion molecules

  1995cited by this paper
• Selective cytokine gene expression in renal cell carcinoma tumor cells and tumor‐infiltrating lymphocytes

  1995cited by this paper
• GM-CSF enhances IL-2-activated natural killer cell lysis of clonogenic AML cells by upregulating target cell expression of ICAM-1.

  1995cited by this paper
• In vitro generation of immune effector cells from tumor-associated lymphocytes of human gastric cancer.

  1995cited by this paper
• Adoptive immunotherapy with activated peripheral blood lymphocytes.

  1994cited by this paper
• Tumor-infiltrating lymphocytes: their phenotype, functions and clinical use

  1994cited by this paper
• Characterization of autologous tumor‐specific T‐helper 2 cells in tumor‐infiltrating lymphocytes from a patient with metastatic melanoma

  1994cited by this paper
• Lymphokine‐activated killer cell activity of peripheral blood, spleen, regional lymph node, and tumor infiltrating lymphocytes in gastric cancer patients

  1994cited by this paper
• Long-term serum/plasma-free culture of human cytotoxic T lymphocytes induced from peripheral blood mononuclear cells.

  1994cited by this paper
• Characterization of tumor-infiltrating lymphocyte subsets from human renal cell carcinoma: specific reactivity defined by cytotoxicity, interferon-gamma secretion, and proliferation.

  1994cited by this paper
• Phenotypical and functional characteristics of tumor-infiltrating lymphocytes from colon carcinomas stimulated with rIL-2 and rIL-4 in vitro: comparison with lymphocytes of the normal colon mucosa and the peripheral blood.

  1994influential reference
• Interactions between tumor cells and tumor infiltrating lymphocytes in human ovarian carcinoma.

  1994cited by this paper
• Comparative study of interphase cytogenetics, flow cytometric analysis, and nuclear grade of fine‐needle aspirates of breast carcinoma

  1994cited by this paper
• Tumor specific cytolysis by tumor infiltrating lymphocytes in breast cancer

  1994cited by this paper
• Activation of T lymphocytes for the adoptive immunotherapy of cancer

  1994cited by this paper
• Reactivation of murine tumour-infiltrating lymphocytes with solid-phase anti-CD3 antibody: in vitro cytokine production is associated with in vivo efficacy.

  1994cited by this paper
• Cellular immune response to human renal‐cell carcinomas: Definition of a common antigen recognized by HLA‐A2‐restricted cytotoxic T‐Lymphocyte (CTL) clones

  1994cited by this paper
• Multiple sub‐sets of Cd4+ and Cd8+ cytotoxic T‐cell clones directed to autologous human melanoma identified by cytokine profiles

  1994cited by this paper
• Immunomodulation in patients with epithelial ovarian cancer after adoptive transfer of tumor-infiltrating lymphocytes.

  1994cited by this paper
• Fluorescence in situ hybridization analysis of trisomy 12 in ovarian tumors.

  1994cited by this paper
• Autologous Tumor-Cell Vaccination and Lymphokine-Activated Tumor-Infiltrating Lymphocytes (LAK-TIL)

  1993cited by this paper
• Phenotypes of lymphocytes infiltrating non-small cell lung cancer tissues and its variation with histological types of cancer.

  1993cited by this paper
• Adoptive immunotherapy of advanced melanoma patients with interleukin-2 (IL-2) and tumor-infiltrating lymphocytes selected in vitro with low doses of IL-2

  1993cited by this paper
• Detection of intracellular cytokines by flow cytometry.

  1993cited by this paper
• Establishment and characterization of 7 ovarian carcinoma cell lines and one granulosa tumor cell line: Growth features and cytogenetics

  1993cited by this paper
• Cytokine production by T-cell lines derived from tumor-infiltrating lymphocytes from patients with ovarian carcinoma: tumor-specific immune responses and inhibition of antigen-independent cytokine production by ovarian tumor cells.

  1993cited by this paper
• Immunotherapy of ovarian cancer. II. In vitro generation and characterization of lymphokine‐activated killer T cells from the peripheral blood of recurrent ovarian cancer patients

  1992influential reference
• Trisomy 7 and trisomy 10 characterize subpopulations of tumor-infiltrating lymphocytes in kidney tumors and in the surrounding kidney tissue.

  1992cited by this paper
• Signalling in human tumour infiltrating lymphocytes: the CD28 molecule is functional and is physically associated with the CD45R0 molecule.

  1992cited by this paper
• Characterization of lymphocytes infiltrating human breast cancer: specific immune reactivity detected by measuring cytokine secretion.

  1992cited by this paper
• Novel immunologic strategies in ovarian carcinoma

  1992cited by this paper
• Lymphokine-Activated Tumor-Infiltrating Lymphocytes and Autologous tumor Vaccine in Breast and Ovarian Cancer

  1992cited by this paper
• Expression of mRNA for cytokines in tumor‐infiltrating mononuclear cells in ovarian adenocarcinoma and invasive breast cancer

  1992cited by this paper
• Phenotypic analysis of tumor-infiltrating lymphocytes from human breast cancer.

  1992influential reference
• Clinical results and characterization of tumor-infiltrating lymphocytes with or without recombinant interleukin 2 in human metastatic renal cell carcinoma.

  1991cited by this paper
• Cytotoxicity assays using cryopreserved target cells pre-labeled with the fluorescent marker europium.

  1990cited by this paper
• TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties.

  1989cited by this paper
• Immunotherapy of patients with advanced cancer using tumor-infiltrating lymphocytes and recombinant interleukin-2: a pilot study.

  1988cited by this paper
• Ovarian-tumor-infiltrating lymphocytes: phenotype and antitumor activity.

  1988cited by this paper
• Metastatic renal cancer treated with interleukin-2 and lymphokine-activated killer cells. A phase II clinical trial.

  1988influential reference
• Use of tumor-infiltrating lymphocytes and interleukin-2 in the immunotherapy of patients with metastatic melanoma. A preliminary report.

  1988cited by this paper
• Adoptive immunotherapy of human cancer using low-dose recombinant interleukin 2 and lymphokine-activated killer cells.

  1988influential reference

• A combination treatment with a water extract from Euglena gracilis and anti-PD-1 antibody strongly inhibits growth of lung cancer in mice through stimulating tumor-infiltrating lymphocytes.

  2025cites this paper
• Tumor‐infiltrating CD8+ T‐cell numbers and serum C‐reactive protein levels as a prognostic biomarker in hepatocellular carcinoma patients receiving atezolizumab plus bevacizumab

  2025cites this paper
• Tumor‑infiltrating CD8+ T cells as a biomarker for chemotherapy efficacy in unresectable hepatocellular carcinoma

  2023cites this paper
• Impact of CyberKnife Radiosurgery on Overall Survival and Various Parameters of Patients with 1-3 versus ≥ 4 Brain Metastases

  2017cites this paper
• An Overview of Treatment for Cervical Cancer with Emphasis on Immune Cell-Based Therapies

  2015cites this paper
• The Evaluation of Serum Levels of IFN- δ , IL-12 and Percentage of CD4 + , CD8 + and NK Cells in Peripheral Blood of Metastatic, Nonmetastatic Breast Cancer Patients and Normal Individuals

  2013cites this paper
• Immune suppression and evasion in patients with head and neck cancer

  2013cites this paper
• CD8+ lymphocyte infiltration is an independent favorable prognostic indicator in basal-like breast cancer

  2012cites this paper
• Caracterização da resposta imune celular pela expressão imunoistoquímica de CD4, CD8, CD28, CD152, CD56 e FOXP3 em carcinoma mamário de fêmeas caninas

  2012cites this paper
• Peri- and intratumoral T and B lymphocytic infiltration in breast cancer.

  2008cites this paper
• Clinical significance of tumor-infiltrating lymphocytes in neoplastic progression and lymph node metastasis of human breast cancer.

  2008cites this paper
• CHAPTER 41 – Psychosocial Influences in Oncology: An Expanded Model of Biobehavioral Mechanisms

  2007cites this paper
• Relationships between regulatory T cells and CD8+ effector populations in patients with squamous cell carcinoma of the head and neck

  2007cites this paper
• Changes in the Ratio of Tc1/Tc2 and Th1/Th2 Cells but Not in Subtypes of NK-Cells in Preeclampsia

  2007cites this paper
• Harnessing the regulatory feedback to T cells to enhance antitumor immune responses

  2006cites this paper
• Maturation of circulating dendritic cells and imbalance of T-cell subsets in patients with squamous cell carcinoma of the head and neck

  2006cites this paper
• Investigation of NK Cell Population in Peripheral Blood and Tumor Lesions of Patients with Breast Cancer

  2005cites this paper
• Multimodales Management maligner Ovarialtumore

  2005cites this paper
• Social support, psychological distress, and natural killer cell activity in ovarian cancer.

  2005cites this paper
• Chapter 27 – Pathology of Ovarian, Fallopian Tube, and Primary Peritoneal Cancer

  2004cites this paper
• IL-4 Protects Tumor Cells from Anti-CD95 and Chemotherapeutic Agents via Up-Regulation of Antiapoptotic Proteins1

  2004cites this paper
• Differential Tumor Microenvironment in Human Ovarian Cystic Tumors

  2004cites this paper
• Up-Regulation of Antiapoptotic Proteins and Chemotherapeutic Agents via IL-4 Protects Tumor Cells from Anti-CD95

  2004cites this paper
• The 4H84 monoclonal antibody detecting beta2m free nonclassical HLA-G molecules also binds to free heavy chains of classical HLA class I antigens present on activated lymphocytes.

  2004cites this paper
• Biological and clinical impact of IL-6 production by ovarian carcinoma cells

  2003cites this paper
• Immunohistochemical evaluation of immune response in invasive ductal breast cancer of not-otherwise-specified type.

  2003cites this paper
• Characteristic Cytokine Generation Patterns in Cancer Cells and Infiltrating Lymphocytes in Oral Squamous Cell Carcinomas and the Influence of Chemoradiation Combined with Immunotherapy on These Patterns

  2003cites this paper
• The clinical significance of CD8+ T cell subset abnormalities in common human malignancies

  2002cites this paper
• Cytokine expression in peripheral blood lymphocytes indicates a switch to T(HELPER) cells in patients with preeclampsia.

  2002cites this paper
• Prognostic value of CD4+ lymphocytes in pleural cavity of patients with non-small cell lung cancer

  2001cites this paper
• Clinical significance of serum and ascitic p53 autoantibodies in epithelial ovarian carcinoma

  2000cites this paper
• Ex vivo assays to evaluate the role of protein kinase C in tumor cells of patients with breast cancer.

  2000cites this paper
• Pregnancy as a Model of Controlled Invasion Might Be Attributed to the Ratio of CD3/CD8 to CD56

  2000influential citation
• IL-6 production in ovarian carcinoma is associated with histiotype and biological characteristics of the tumour and influences local immunity

  2000cites this paper
• The Fas counterattack: cancer as a site of immune privilege.

  1999cites this paper
• The immunology and immunotherapy of breast cancer: an update.

  1999cites this paper
• Tumor Immune Privilege Human Breast Cancers : Significance for Expression of Fas ( CD 95 / APO-1 ) Ligand by

  1999cites this paper
• The role of cytokines in both the normal and malignant ovary.

  1999cites this paper
• Isolation of MUC1-primed B lymphocytes from tumour-draining lymph nodes by immunomagnetic beads

  1999cites this paper
• The relationship of host immune cells, cytokine and nitric oxide production to tumor cells in ovarian carcinoma.

  1999cites this paper
• Therapeutic aspects of polymorphic epithelial mucin in adenocarcinoma.

  1999cites this paper
• Expression of Fas (CD95/APO-1) Ligand by Human Breast Cancers: Significance for Tumor Immune Privilege

  1999cites this paper
• Ascitic interleukin-12 is an independent prognostic factor in ovarian cancer.

  1998cites this paper
• Immunotherapy and breast cancer.

  1998cites this paper
• Mucin based breast cancer vaccines.

  1998cites this paper
• Immunologic Features of Tumor-Infiltrating Lymphocytes and Peripheral Blood Lymphocytes in Overian Cancer Patients

  1998cites this paper