Immunoelectron microscopy shows a clustered distribution of NADPH oxidase components in the human neutrophil plasma membrane

No abstract is available for this paper.

• Publication year

  1997

• Venue

  Journal of Leukocyte Biology

• Publication date

  1997-03-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1002/jlb.61.3.303PMID 9060453
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Interactions between cytosolic components of the NADPH oxidase: p40phox interacts with both p67phox and p47phox.

  1996cited by this paper
• Dissociation of Rac translocation from p47phox/p67phox movements in human neutrophils by tyrosine kinase inhibitors

  1995cited by this paper
• Function of wild-type or mutant Rac2 and Rap1a GTPases in differentiated HL60 cell NADPH oxidase activation.

  1995cited by this paper
• Mapping the Domains of Interaction of p40 with Both p47 and p67 of the Neutrophil Oxidase Complex Using the Two-hybrid System (*)

  1995cited by this paper
• NADPH oxidase and the respiratory burst.

  1995cited by this paper
• Translocation of p21rac2 from cytosol to plasma membrane is neither necessary nor sufficient for neutrophil NADPH oxidase activity

  1995cited by this paper
• Interactions between the cytosolic components p47phox and p67phox of the human neutrophil NADPH oxidase that are not required for activation in the cell-free system

  1995cited by this paper
• Activation of NADPH oxidase involves the dissociation of p21rac from its inhibitory GDP/GTP exchange protein (rhoGDI) followed by its translocation to the plasma membrane.

  1994cited by this paper
• Role of Src homology 3 domains in assembly and activation of the phagocyte NADPH oxidase.

  1994cited by this paper
• Remodeling of the plasma membrane after stimulation of neutrophils with f‐Met‐Leu‐Phe and dihydrocytochalasin B: identification of membrane subdomains containing NADPH oxidase activity

  1994cited by this paper
• Production of antisera to synthetic peptides.

  1994cited by this paper
• An SH3 domain and proline-rich sequence mediate an interaction between two components of the phagocyte NADPH oxidase complex.

  1994cited by this paper
• Chronic granulomatous disease.

  1994cited by this paper
• Cytosolic guanine nucleotide-binding protein Rac2 operates in vivo as a component of the neutrophil respiratory burst oxidase. Transfer of Rac2 and the cytosolic oxidase components p47phox and p67phox to the submembranous actin cytoskeleton during oxidase activation.

  1994cited by this paper
• Rac translocates independently of the neutrophil NADPH oxidase components p47phox and p67phox. Evidence for its interaction with flavocytochrome b558.

  1994cited by this paper
• The small GTP-binding protein rac is not recruited to the plasma membrane upon NADPH oxidase activation in human neutrophils.

  1994cited by this paper
• Assembly of the phagocyte NADPH oxidase: binding of Src homology 3 domains to proline-rich targets.

  1994cited by this paper
• Translocation of Rac correlates with NADPH oxidase activation. Evidence for equimolar translocation of oxidase components.

  1993cited by this paper
• p40phox, a third cytosolic component of the activation complex of the NADPH oxidase to contain src homology 3 domains.

  1993cited by this paper
• Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. 1979.

  1992cited by this paper
• The cytosolic components of the respiratory burst oxidase exist as a M(r) approximately 240,000 complex that acquires a membrane-binding site during activation of the oxidase in a cell-free system.

  1992cited by this paper
• Cytochrome b558: the flavin-binding component of the phagocyte NADPH oxidase.

  1992cited by this paper
• Cytochrome b-245 is a flavocytochrome containing FAD and the NADPH-binding site of the microbicidal oxidase of phagocytes.

  1992cited by this paper
• Reconstitution of neutrophil NADPH oxidase activity in the cell-free system by four components: p67-phox, p47-phox, p21rac1, and cytochrome b-245.

  1992cited by this paper
• Topology of cytochrome b558 in neutrophil membrane analyzed by anti-peptide antibodies and proteolysis.

  1992cited by this paper
• Inhibition of superoxide production in B lymphocytes by rac antisense oligonucleotides.

  1992cited by this paper
• Chronic granulomatous disease

  1991cited by this paper
• Regulation of phagocyte oxygen radical production by the GTP-binding protein Rac 2.

  1991cited by this paper
• Assembly of the neutrophil respiratory burst oxidase. Protein kinase C promotes cytoskeletal and membrane association of cytosolic oxidase components.

  1991cited by this paper
• Respiratory burst oxidase and three of four oxidase-related polypeptides are associated with the cytoskeleton of human neutrophils.

  1991cited by this paper
• Activation of the NADPH oxidase involves the small GTP-binding protein p21rac1

  1991cited by this paper
• Neutrophil nicotinamide adenine dinucleotide phosphate oxidase assembly. Translocation of p47-phox and p67-phox requires interaction between p47-phox and cytochrome b558.

  1991cited by this paper
• Evidence for a functional cytoplasmic domain of phagocyte oxidase cytochrome b558.

  1990cited by this paper
• Characterization of the 47-kilodalton autosomal chronic granulomatous disease protein: tissue-specific expression and transcriptional control by retinoic acid

  1990cited by this paper
• Ultrastructural localization of cytochrome b in the membranes of resting and phagocytosing human granulocytes.

  1990cited by this paper
• The phagocyte 47-kilodalton cytosolic oxidase protein is an early reactant in activation of the respiratory burst.

  1990cited by this paper
• Cloning of a 67-kD neutrophil oxidase factor with similarity to a noncatalytic region of p60c-src.

  1990cited by this paper
• Recombinant 47-kilodalton cytosol factor restores NADPH oxidase in chronic granulomatous disease.

  1989cited by this paper
• Cloning of the cDNA and functional expression of the 47-kilodalton cytosolic component of human neutrophil respiratory burst oxidase.

  1989cited by this paper
• rac, a novel ras-related family of proteins that are botulinum toxin substrates.

  1989cited by this paper
• Association of gelsolin with actin filaments and cell membranes of macrophages and platelets

  1989cited by this paper
• Two cytosolic neutrophil oxidase components absent in autosomal chronic granulomatous disease.

  1988cited by this paper
• Threshold responses in production of reactive oxygen metabolites in individual neutrophils detected by flow cytometry and microfluorimetry.

  1987cited by this paper
• Stimulated neutrophils from patients with autosomal recessive chronic granulomatous disease fail to phosphorylate a Mr-44,000 protein

  1985cited by this paper
• Changes in the subcellular distribution of the cytochrome b-245 on stimulation of human neutrophils.

  1984cited by this paper
• Subcellular localization of the b-cytochrome component of the human neutrophil microbicidal oxidase: translocation during activation

  1983cited by this paper
• Sizing of protein A-colloidal gold probes for immunoelectron microscopy

  1981cited by this paper
• Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

  1979cited by this paper
• Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

  1970cited by this paper

• Consequences of the constitutive NOX2 activity in living cells: cytosol acidification, apoptosis, and localized lipid peroxidation

  2021cites this paper
• ROS as Regulators of Cellular Processes in Melanoma

  2021cites this paper
• Improved unroofing protocols for cryo-electron microscopy, atomic force microscopy and freeze-etching electron microscopy and the associated mechanisms.

  2020cites this paper
• Membrane Dynamics and Organization of the Phagocyte NADPH Oxidase in PLB-985 Cells

  2020cites this paper
• Chapter 16 – Electrophilic Nitro-Fatty Acids: Nitric Oxide and Nitrite-Derived Metabolic and Inflammatory Signaling Mediators

  2017cites this paper
• Formation of Nitrated Lipids and Their Biological Relevance

  2015cites this paper
• Dynamic changes in the subcellular distribution of the tobacco ROS-producing enzyme RBOHD in response to the oomycete elicitor cryptogein

  2014cites this paper
• Nitroarachidonic acid prevents NADPH oxidase assembly and superoxide radical production in activated macrophages.

  2013cites this paper
• Cholesterol load of microglia: contribution of membrane architecture changes to neurotoxic power?

  2013cites this paper
• Anionic lipid-induced conformational changes in human phagocyte flavocytochrome b precede assembly and activation of the NADPH oxidase complex.

  2012cites this paper
• [Analysis of p22-phox and p47-phox subcellular localization and distribution in neutrophils from human immunodeficiency virus (HIV) infected patients].

  2012cites this paper
• Función de los polimorfonucleares en la cirrosis hepática

  2012cites this paper
• Role of Intracellular Oxidant Release in Oxidised Low Lipoprotein - Induced U937 Cell Death

  2012cites this paper
• Localización y distribución celular de p22-phox y p47-phox en neutrófilos humanos de pacientes infectados con VIH

  2012cites this paper
• Redox Regulation of Endothelial Canonical Transient Receptor Potential Channels

  2011cites this paper
• Effect of cytochalasin D on the respiratory burst of primed neutrophils activated with a secondary stimulus

  2009cites this paper
• Platelet particle formation by anti GPIIIa49-66 Ab, Ca2+ ionophore A23187, and phorbol myristate acetate is induced by reactive oxygen species and inhibited by dexamethasone blockade of platelet phospholipase A2, 12-lipoxygenase, and NADPH oxidase.

  2007cites this paper
• Granulocyte activation by danger signals and blocking of receptor responses

  2007cites this paper
• [The Nox/Duox family of ROS-generating NADPH oxidases].

  2006cites this paper
• Les Nox/Duox : une nouvelle famille de NADPH oxydases

  2006cites this paper
• Identification of non-mitochondrial NADPH oxidase and the spatio-temporal organization of its components in mouse spermatozoa.

  2005cites this paper
• Structural organization of the neutrophil NADPH oxidase: phosphorylation and translocation during priming and activation

  2005cites this paper
• p47phox Associates With the Cytoskeleton Through Cortactin in Human Vascular Smooth Muscle Cells: Role in NAD(P)H Oxidase Regulation by Angiotensin II

  2005cites this paper
• p40phox: the last NADPH oxidase subunit.

  2005cites this paper
• Ncf1 (p47phox) polymorphism determines oxidative burst and the severity of arthritis in rats and mice.

  2005cites this paper
• Expression and Modulation of an NADPH Oxidase in Mammalian Astrocytes

  2005cites this paper
• The phagocyte NADPH oxidase depends on cholesterol‐enriched membrane microdomains for assembly

  2004cites this paper
• Angiotensin II Impairs Neurovascular Coupling in Neocortex Through NADPH Oxidase–Derived Radicals

  2004cites this paper
• Complement-independent Ab-induced peroxide lysis of platelets requires 12-lipoxygenase and a platelet NADPH oxidase pathway.

  2004cites this paper
• Lipid rafts determine efficiency of NADPH oxidase activation in neutrophils

  2003cites this paper
• NADPH oxidase immunoreactivity in the mouse brain.

  2003cites this paper
• Interactions between Electron and Proton Currents in Excised Patches from Human Eosinophils

  2003cites this paper
• Essential Role of the NADPH Oxidase Subunit p47phox in Endothelial Cell Superoxide Production in Response to Phorbol Ester and Tumor Necrosis Factor-&agr;

  2002cites this paper
• Intracellular Localization and Preassembly of the NADPH Oxidase Complex in Cultured Endothelial Cells*

  2002cites this paper
• Production in Response to Phorbol Ester and Tumor Necrosis Factor-in Endothelial Cell SuperoxidephoxEssential Role of the NADPH Oxidase Subunit p 47

  2002cites this paper
• Apparent role of traveling metabolic waves in oxidant release by living neutrophils

  2002cites this paper
• Salmonella evasion of the NADPH phagocyte oxidase.

  2001cites this paper
• The NADPH oxidase components p47(phox) and p40(phox) bind to moesin through their PX domain.

  2001cites this paper
• Evaluation of the process for superoxide production by NADPH oxidase in human neutrophils: evidence for cytoplasmic origin of superoxide

  2001cites this paper
• The PX domains of p47phox and p40phox bind to lipid products of PI(3)K

  2001cites this paper
• Differential NADPH- versus NADH-dependent superoxide production by phagocyte-type endothelial cell NADPH oxidase.

  2001cites this paper
• Molecular characterization and localization of the NAD(P)H oxidase components gp91-phox and p22-phox in endothelial cells.

  2000cites this paper
• Direct interaction of actin with p47(phox) of neutrophil NADPH oxidase.

  2000cites this paper
• P67-phox-mediated NADPH oxidase assembly: imaging of cytochrome b558 liposomes by atomic force microscopy.

  2000cites this paper
• Genetic, biochemical, and clinical features of chronic granulomatous disease.

  2000cites this paper
• Deactivation of neutrophil NADPH oxidase by actin-depolymerizing agents in a cell-free system.

  2000cites this paper
• Cytochrome b558 (p22phox) in the guinea‐pig adrenal medulla

  1999cites this paper
• NADPH oxidase: an update.

  1999cites this paper
• Structure and Regulation of NADPH Oxidase of Phagocytic Leukocytes

  1999cites this paper
• Expression of functional neutrophil-type NADPH oxidase in cultured rat coronary microvascular endothelial cells.

  1998cites this paper
• Organization and mobility of CD11b/CD18 and targeting of superoxide on the surface of degranulated human neutrophils.

  1998cites this paper
• Membrane association and targeting of prenylated Ras-like GTPases.

  1998cites this paper
• Perfluoroalkylphosphocholines are poor protein-solubilizing surfactants, as tested with neutrophil plasma membranes.

  1998cites this paper