Effects of enhancing mitochondrial oxidative phosphorylation with reducing equivalents and ubiquinone on 1-methyl-4-phenylpyridinium toxicity and complex I-IV damage in neuroblastoma cells.

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Biochemical Pharmacology

• Publication date

  2004-03-15

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1016/J.BCP.2003.11.016PMID 15006552
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Pyruvic acid cytoprotection against 1-methyl-4-phenylpyridinium, 6-hydroxydopamine and hydrogen peroxide toxicities in vitro.

  2003cited by this paper
• MPP(+) causes inhibition of cellular energy supply in cerebellar granule cells.

  2003cited by this paper
• Mitochondrial polymorphisms significantly reduce the risk of Parkinson disease.

  2003cited by this paper
• Understanding ATP synthesis: structure and mechanism of the F1-ATPase (Review)

  2003cited by this paper
• Understanding ATP synthesis: structure and mechanism of the F1-ATPase (Review).

  2003cited by this paper
• The role of glycolysis and gluconeogenesis in the cytoprotection of neuroblastoma cells against 1-methyl 4-phenylpyridinium ion toxicity.

  2003cited by this paper
• D-(+)-glucose rescue against 1-methyl-4-phenylpyridinium toxicity through anaerobic glycolysis in neuroblastoma cells.

  2003cited by this paper
• Coenzyme Q10 supplementation provides mild symptomatic benefit in patients with Parkinson's disease.

  2003cited by this paper
• Striking Differences in Glucose and Lactate Levels between Brain Extracellular Fluid and Plasma in Conscious Human Subjects: Effects of Hyperglycemia and Hypoglycemia

  2002cited by this paper
• Down-regulation of mitochondrial cytochrome c oxidase in senescent porcine pulmonary artery endothelial cells.

  2002cited by this paper
• Environment, Mitochondria, and Parkinson's Disease

  2002cited by this paper
• Mutant and wild-type alpha-synuclein interact with mitochondrial cytochrome C oxidase.

  2002cited by this paper
• The molecular mechanism of ATP synthesis by F1F0-ATP synthase: a scrutiny of the major possibilities.

  2002cited by this paper
• Inhibition of the mitochondrial respiratory chain complex activities in rat cerebral cortex by methylmalonic acid.

  2002cited by this paper
• Glucose/mitochondria in neurological conditions.

  2002cited by this paper
• Dopamine-derived endogenous N-methyl-(R)-salsolinol: its role in Parkinson's disease.

  2002cited by this paper
• [Tetrahydroisoquinoline derivatives as possible Parkinson's disease-inducing substances].

  2002cited by this paper
• An In Vitro Model of Parkinson's Disease: Linking Mitochondrial Impairment to Altered α-Synuclein Metabolism and Oxidative Damage

  2002cited by this paper
• L-Deprenyl prevents the cell hypoxia induced by dopaminergic neurotoxins, MPP(+) and beta-carbolinium: a microdialysis study in rats.

  2001cited by this paper
• Ubiquinone (Coenzyme Q10) and Mitochondria in Oxidative Stress of Parkinson’s Disease

  2001cited by this paper
• Development of a high throughput in vitro toxicity screen predictive of high acute in vivo toxic potential.

  2001cited by this paper
• Complex I and Parkinson's Disease

  2001cited by this paper
• Effect of changing tumor oxygenation on glycolytic metabolism in a murine C3H mammary carcinoma assessed by in vivo nuclear magnetic resonance spectroscopy.

  2001cited by this paper
• Lactate efflux and the neuroenergetic basis of brain function

  2001cited by this paper
• [Pathogenesis of idiopathic Parkinson's disease].

  2001cited by this paper
• Decreased expression of the NADH:ubiquinone oxidoreductase (complex I) subunit 4 in 1-methyl-4-phenylpyridinium -treated human neuroblastoma SH-SY5Y cells.

  2001cited by this paper
• Oxidative metabolites of 5-S-cysteinyldopamine inhibit the α-ketoglutarate dehydrogenase complex: possible relevance to the pathogenesis of Parkinson's disease

  2000cited by this paper
• Chronic systemic pesticide exposure reproduces features of Parkinson's disease

  2000cited by this paper
• Effects of nicotinamide and carbogen on tumour oxygenation, blood flow, energetics and blood glucose levels

  2000cited by this paper
• 1-Methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline (salsolinol) is toxic to dopaminergic neuroblastoma SH-SY5Y cells via impairment of cellular energy metabolism.

  2000cited by this paper
• An inducible gene product for 6-phosphofructo-2-kinase with an AU-rich instability element: role in tumor cell glycolysis and the Warburg effect.

  1999cited by this paper
• Role of Mitochondria in Parkinson Disease

  1999cited by this paper
• Extracellular lactate and glucose alterations in the brain after head injury measured by microdialysis.

  1999cited by this paper
• Mitochondrial dysfunction in Parkinson's disease.

  1999cited by this paper
• [Positron emission tomography (PET) and (F-18)-fluorodeoxyglucose in (FDG) in cancerology].

  1998cited by this paper
• Tomographie par émission de positons (TEP) et [F-18]-fluorodésoxyglucose (FDG) en cancérologie

  1998cited by this paper
• Mitochondrial DNA transmission of the mitochondrial defect in Parkinson's disease

  1998cited by this paper
• A dual effect of 1-methyl-4-phenylpyridinium (MPP+)-analogs on the respiratory chain of bovine heart mitochondria.

  1997cited by this paper
• Coenzyme Q deficiency in mitochondria: kinetic saturation versus physical saturation.

  1997cited by this paper
• Tumor hypoxia adversely affects the prognosis of carcinoma of the head and neck.

  1997cited by this paper
• MPP(+)-induced neurotoxicity in mouse is age-dependent: evidenced by the selective inhibition of complexes of electron transport.

  1996cited by this paper
• Coenzyme Q, peroxidation and cytochrome oxidase features after Parkinson's-like disease by MPTP toxicity in intra-synaptic and non-synaptic mitochondria fromMacaca Fascicularis cerebral cortex and hippocampus: action of dihydroergocriptine

  1996cited by this paper
• Cerebral oxygen and glucose metabolism and blood flow in mitochondrial encephalomyopathy: a PET study

  1996cited by this paper
• Riboflavin-responsive complex I deficiency.

  1995cited by this paper
• Biochemical evaluations in skeletal muscles of primates with MPTP Parkinson-like syndrome.

  1995cited by this paper
• Biochemistry, 2nd ed.

  1995cited by this paper
• Inhibition of complex I by isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).

  1995cited by this paper
• Evaluation of hyperbaric oxygen as a chemosensitizer in the treatment of epithelial ovarian cancer in xenografts in mice

  1995cited by this paper
• Effects of 1‐Methyl‐4‐Phenylpyridinium on Isolated Rat Brain Mitochondria: Evidence for a Primary Involvement of Energy Depletion

  1994cited by this paper
• Vitamin-responsive complex I deficiency in a myopathic patient with increased activity of the terminal respiratory chain and lactic acidosis

  1994cited by this paper
• Late‐onset riboflavin‐responsive myopathy with combined multiple acyl coenzyme A dehydrogenase and respiratory chain deficiency

  1994cited by this paper
• Electron transfer complexes I and IV of platelets are abnormal in Parkinson's disease but normal in Parkinson-plus syndromes.

  1993cited by this paper
• Physiological Stimulation Increases Nonoxidative Glucose Metabolism in the Brain of the Freely Moving Rat

  1993cited by this paper
• Is complex II involved in the inhibition of mitochondrial respiration by N-methyl-4-phenylpyridinium cation (MMP+) and N-methyl-beta-carbolines?

  1993cited by this paper
• Mitochondria1 respiratory chain activity in skeletal muscle from patients with Parkinson's disease

  1993cited by this paper
• Mitochondrial respiratory chain activity in skeletal muscle from patients with Parkinson's disease.

  1993cited by this paper
• Selective inhibition of complex I by N-methylisoquinolinium ion and N-methyl-1,2,3,4-tetrahydroisoquinoline in isolated mitochondria prepared from mouse brain.

  1992cited by this paper
• Irreversible Inhibition of Mitochondrial Complex I by 1‐Methyl‐4‐Phenylpyridinium: Evidence for Free Radical Involvement

  1992cited by this paper
• Inhibition of mitochondrial succinate oxidation--similarities and differences between N-methylated beta-carbolines and MPP+.

  1992cited by this paper
• Deviant energetic metabolism of glycolytic cancer cells.

  1992cited by this paper
• Mitochondrial DNA and Parkinson's disease

  1991cited by this paper
• Respiratory chain abnormalities in skeletal muscle from patients with Parkinson's disease.

  1991cited by this paper
• Mitochondrial DNA and Parkinson's disease

  1991cited by this paper
• Glucose determination in samples taken by microdialysis by peroxidase-catalyzed luminol chemiluminescence.

  1991cited by this paper
• [Contribution of MPTP to studies on the pathogenesis of Parkinson's disease].

  1989cited by this paper
• Neurotoxicity of MPTP and MPP+ in vitro: characterization using specific cell lines.

  1988cited by this paper
• Effects of 1‐Methyl‐4‐Phenyl‐1,2,3,6‐Tetrahydropyridine and 1‐Methyl‐4‐Phenylpyridinium Ion on Activities of the Enzymes in the Electron Transport System in Mouse Brain

  1987cited by this paper
• Acyl-CoA dehydrogenase activity in the riboflavin-deficient rat. Effects of starvation.

  1987cited by this paper
• MPTP-induced parkinsonism in human and non-human primates--clinical and experimental aspects.

  1984cited by this paper
• Protein measurement with the Folin phenol reagent.

  1951cited by this paper

• Mechanistic insights into ubiquinone Q10 in Parkinson’s disease: mitochondrial protection, ferroptosis inhibition, and antioxidant recycling

  2025cites this paper
• Metabolic Response to the Mitochondrial Toxin 1-Methyl-4-phenylpyridinium (MPP+) in LDH-A/B Double-knockout LS174T Colon Cancer Cells.

  2021cites this paper
• Neuroglobin overexpression plays a pivotal role in neuroprotection through mitochondrial raft‐like microdomains in neuroblastoma SK‐N‐BE2 cells

  2018cites this paper
• Oxidative Stress: Mechanistic Insights into Inherited Mitochondrial Disorders and Parkinson’s Disease

  2017cites this paper
• Mild MPP+ exposure-induced glucose starvation enhances autophagosome synthesis and impairs its degradation

  2017cites this paper
• Hypothalamic-pituitary-thyroid axis hormones stimulate mitochondrial function and biogenesis in human hair follicles.

  2014cites this paper
• 6 Riboflavin (Vitamin B )

  2013cites this paper
• Supramolecular Organization of the Respiratory Chain

  2012cites this paper
• A Structural Perspective on Respiratory Complex I

  2012cites this paper
• Whole genome expression profile in neuroblastoma cells exposed to 1-methyl-4-phenylpyridine.

  2012cites this paper
• The Effect of Melatonin on Mitochondrial Function in Endotoxemia Induced by Lipopolysaccharide

  2011cites this paper
• The Biochemical and Cellular Basis for Nutraceutical Strategies to Attenuate Neurodegeneration in Parkinson’s Disease

  2011cites this paper
• Thyrotropin powers human mitochondria

  2010cites this paper
• Differential effects of melatonin on amyloid‐β peptide 25–35‐induced mitochondrial dysfunction in hippocampal neurons at different stages of culture

  2010cites this paper
• Evaluation of endogenous acidic metabolic products associated with carbohydrate metabolism in tumor cells

  2010influential citation
• Iptakalim ameliorates MPP+‐induced astrocyte mitochondrial dysfunction by increasing mitochondrial complex activity besides opening mitoKATP channels

  2009cites this paper
• Supramolecular organization of protein complexes in the mitochondrial inner membrane.

  2009cites this paper
• Ginsenoside Rg1 delays tert-butyl hydroperoxide-induced premature senescence in human WI-38 diploid fibroblast cells.

  2008cites this paper
• Mechanism of mitochondrial uncouplers, inhibitors, and toxins: focus on electron transfer, free radicals, and structure-activity relationships.

  2005cites this paper
• Measurement of mitochondrial respiration in permeabilized murine neuroblastoma (N-2alpha) cells, a simple and rapid in situ assay to investigate mitochondrial toxins.

  2005cites this paper