[Physiopathology of primary hyperlipidemias].

No abstract is available for this paper.

• Publication year

  1986

• Venue

  Annales de medecine interne

• Publication date

  Unknown publication date

• Fields of study

  Medicine

• Identifiers
  PMID 3521430
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The locus for apolipoprotein E (apoE) is close to the Lutheran (Lu) blood group locus on chromosome 19

  2004cited by this paper
• Apolipoprotein C-II deficiency associated with nonfunctional mutant forms of apolipoprotein C-II.

  1984cited by this paper
• Use of monoclonal anti-receptor antibodies to probe the expression of the low density lipoprotein receptor in tissues of normal and Watanabe heritable hyperlipidemic rabbits.

  1984cited by this paper
• Type III hyperlipoproteinemia: recent insights into the genetic defect of familial dysbetalipoproteinemia.

  1984cited by this paper
• Characterization with zonal ultracentrifugation of low-density lipoproteins in type V hyperlipoproteinemia.

  1984cited by this paper
• Assignment of the human gene for the low density lipoprotein receptor to chromosome 19: synteny of a receptor, a ligand, and a genetic disease.

  1984cited by this paper
• Normalization of receptor binding of apolipoprotein E2. Evidence for modulation of the binding site conformation.

  1984cited by this paper
• The locus for apolipoprotein CII is closely linked to the apolipoprotein E locus on chromosome 19 in man

  1984cited by this paper
• Liver transplantation to provide low-density-lipoprotein receptors and lower plasma cholesterol in a child with homozygous familial hypercholesterolemia.

  1984cited by this paper
• A novel electrophoretic variant of human apolipoprotein E. Identification and characterization of apolipoprotein E1.

  1984cited by this paper
• Familial apolipoprotein CII deficiency: A preliminary analysis of the gene defect in two independent families

  1984cited by this paper
• Metabolism of apolipoprotein B in large triglyceride-rich very low density lipoproteins of normal and hypertriglyceridemic subjects.

  1984cited by this paper
• Diminished insulin receptors on monocytes and erythrocytes in hypertriglyceridemia.

  1984cited by this paper
• Characterization of hepatic low density lipoprotein binding and cholesterol metabolism in normal and homozygous familial hypercholesterolemic subjects.

  1984cited by this paper
• The uptake of chylomicron remnants and very low density lipoprotein remnants by the perfused rat liver.

  1984cited by this paper
• Functionally inactive apolipoprotein E3 in a type III hyperlipoproteinaemic patient

  1984cited by this paper
• Atypical familial dysbetalipoproteinemia associated with apolipoprotein phenotype E3/3.

  1983cited by this paper
• The LDL receptor locus in familial hypercholesterolemia: multiple mutations disrupt transport and processing of a membrane receptor.

  1983cited by this paper
• Defective lipoprotein receptors and atherosclerosis. Lessons from an animal counterpart of familial hypercholesterolemia.

  1983cited by this paper
• Phenotypic heterogeneity in the extended pedigree of a proband with lipoprotein lipase deficiency.

  1983cited by this paper
• Apolipoprotein EBethesda: a new variant of apolipoprotein E associated with type III hyperlipoproteinemia.

  1983cited by this paper
• Overproduction of Low Density Lipoproteins Associated with Coronary Heart Disease

  1983cited by this paper
• Regulation of hepatic lipoprotein receptors in the dog. Rapid regulation of apolipoprotein B,E receptors, but not of apolipoprotein E receptors, by intestinal lipoproteins and bile acids.

  1983cited by this paper
• The receptor-binding domain of human apolipoprotein E. Binding of apolipoprotein E fragments.

  1983cited by this paper
• Identification of a new structural variant of human apolipoprotein E, E2(Lys146 leads to Gln), in a type III hyperlipoproteinemic subject with the E3/2 phenotype.

  1983cited by this paper
• The receptor-binding domain of human apolipoprotein E. Monoclonal antibody inhibition of binding.

  1983cited by this paper
• Enhanced Macrophage Degradation of Biologically Modified Low Density Lipoprotein

  1983cited by this paper
• Remnants of Lipoproteins of Intestinal and Hepatic Origin in Familial Dysbetalipoproteinemia

  1983cited by this paper
• [Apolipoproteins. Structure, function and pathological changes].

  1983cited by this paper
• Hepatic catabolism of low density lipoprotein: mechanisms and metabolic consequences.

  1982cited by this paper
• Defective in vitro lipolysis of type IV hyperlipidemic human plasma by purified milk lipoprotein lipase. Studies by single vertical spin centrifugation.

  1982cited by this paper
• Triglyceride and Cholesterol Metabolism in Primary Hypertriglyceridemia

  1982cited by this paper
• Receptor-dependent and receptor-independent degradation of low density lipoprotein in normal rabbits and in receptor-deficient mutant rabbits.

  1982cited by this paper
• Delayed clearance of very low density and intermediate density lipoproteins with enhanced conversion to low density lipoprotein in WHHL rabbits.

  1982cited by this paper
• Increased prevalence of apolipoprotein E4 in type V hyperlipoproteinemia.

  1982cited by this paper
• Low density lipoprotein receptor activity in homozygous familial hypercholesterolemia fibroblasts.

  1982cited by this paper
• Lipoprotein lipase activity of adipose tissue, skeletal muscle and post‐heparin plasma in primary endogenous hypertriglyceridaemia: relation to lipoprotein pattern and to obesity

  1982cited by this paper
• Posttranslational processing of the LDL receptor and its genetic disruption in familial hypercholesterolemia.

  1982cited by this paper
• Structural and metabolic heterogeneity of beta-very low density lipoproteins from cholesterol-fed dogs and from humans with type III hyperlipoproteinemia.

  1982cited by this paper
• Difference in saturable binding of low density lipoprotein to liver membranes from normocholesterolemic subjects and patients with heterozygous familial hypercholesterolemia.

  1982cited by this paper
• Structural basis for receptor binding heterogeneity of apolipoprotein E from type III hyperlipoproteinemic subjects.

  1982cited by this paper
• Human apolipoprotein E. The complete amino acid sequence.

  1982cited by this paper
• Two independent lipoprotein receptors on hepatic membranes of dog, swine, and man. Apo-B,E and apo-E receptors.

  1981cited by this paper
• Type III hyperlipoproteinemia: defective metabolism of an abnormal apolipoprotein E.

  1981cited by this paper
• Intestinal lipoprotein metabolism.

  1981cited by this paper
• Function of hepatic triglyceride lipase in lipoprotein metabolism.

  1981cited by this paper
• Familial apolipoprotein CII deficiency: plasma lipoproteins and apolipoproteins in heterozygous and homozygous subjects and the effects of plasma infusion

  1981cited by this paper
• Human apolipoprotein E isoprotein subclasses are genetically determined.

  1981cited by this paper
• Association of isoapolipoprotein-E3 deficiency with heterozygous familial hypercholesterolaemia: implications for lipoprotein physiology.

  1981cited by this paper
• Defects of receptor-mediated low density lipoprotein catabolism in homozygous familial hypercholesterolemia and hypothyroidism in vivo.

  1981cited by this paper
• Individual variation in the effects of dietary cholesterol on plasma lipoproteins and cellular cholesterol homeostasis in man. Studies of low density lipoprotein receptor activity and 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in blood mononuclear cells.

  1981cited by this paper
• Type III hyperlipoproteinemia associated with apolipoprotein E deficiency.

  1981cited by this paper
• Genetic transmission of isoapolipoprotein E phenotypes in a large kindred: relationship to dysbetalipoproteinemia and hyperlipidemia.

  1981cited by this paper
• Integrated regulation of very low density lipoprotein triglyceride and apolipoprotein-B kinetics in man: normolipemic subjects, familial hypertriglyceridemia and familial combined hyperlipidemia.

  1981cited by this paper
• Human very low density lipoprotein apolipoprotein E isoprotein polymorphism is explained by genetic variation and posttranslational modification.

  1981cited by this paper
• Saturation and suppression of hepatic lipoprotein receptors: a mechanism for the hypercholesterolemia of cholesterol-fed rabbits.

  1981cited by this paper
• Rapid hepatic clearance of the canine lipoproteins containing only the E apoprotein by a high affinity receptor. Identity with the chylomicron remnant transport process.

  1980cited by this paper
• Heterogeneity of primary lipoprotein lipase deficiency.

  1980cited by this paper
• Genetics of the apolipoprotein E system in man.

  1980cited by this paper
• Malondialdehyde alteration of low density lipoproteins leads to cholesteryl ester accumulation in human monocyte-macrophages.

  1980cited by this paper
• Isoprotein specificity in the hepatic uptake of apolipoprotein E and the pathogenesis of familial dysbetalipoproteinemia.

  1980cited by this paper
• Apolipoprotein B metabolism in normal, type IV and type V hyperlipoproteinemic subjects.

  1980cited by this paper
• Kinetic bases of the primary hyperlipidaemias: studies of apolipoprotein B turnover in genetically defined subjects.

  1980cited by this paper
• Cholesteryl ester synthesis in macrophages: stimulation by beta-very low density lipoproteins from cholesterol-fed animals of several species.

  1980cited by this paper
• [Normalization of lipid levels in an 87-year-old woman with a type III dysbetalipoproteinemia by ethinyl estradiol (author's transl)].

  1980cited by this paper
• Increased binding of low density lipoprotein to liver membranes from rats treated with 17 alpha-ethinyl estradiol.

  1979cited by this paper
• Metabolic studies in familial hypercholesterolemia. Evidence for a gene-dosage effect in vivo.

  1979cited by this paper
• Transport of very low density lipoprotein triglycerides in varying degrees of obesity and hypertriglyceridemia.

  1979cited by this paper
• Effects of estrogen therapy on apolipoprotein E in type II hyperlipoproteinemia.

  1979cited by this paper
• Inheritance of apolipoprotein C-II deficiency with hypertriglyceridemia and pancreatitis.

  1978cited by this paper
• Metabolsim of apoB and apoC lipoproteins in man: kinetic studies in normal and hyperlipoproteininemic subjects.

  1978cited by this paper
• Hypertriglyceridemia associated with deficiency of apolipoprotein C-II.

  1978cited by this paper
• Activation of lipoprotein lipase by native and synthetic fragments of human plasma apolipoprotein C-II.

  1977cited by this paper
• Inhibition of lipoprotein binding to cell surface receptors of fibroblasts following selective modification of arginyl residues in arginine-rich and B apoproteins.

  1977cited by this paper
• Primary type V hyperlipoproteinemia. A descriptive study in 32 families.

  1977cited by this paper
• Familial and acquired type V hyperlipoproteinemia.

  1976cited by this paper
• Analysis of a mutant strain of human fibroblasts with a defect in the internalization of receptor-bound low density lipoprotein.

  1976cited by this paper
• Evidence for diabetes mellitus and genetic forms of hypertriglyceridemia as independent entities.

  1975cited by this paper
• Familial hyperlipoproteinemia type III: Deficiency of a specific apolipoprotein (APO E‐III) in the very‐low‐density lipoproteins

  1975cited by this paper
• Selective measurement of two lipase activities in postheparin plasma from normal subjects and patients with hyperlipoproteinemia.

  1974cited by this paper
• Reappraisal of the role of insulin in hypertriglyceridemia.

  1974cited by this paper
• Binding and degradation of low density lipoproteins by cultured human fibroblasts. Comparison of cells from a normal subject and from a patient with homozygous familial hypercholesterolemia.

  1974cited by this paper
• Esterification of low density lipoprotein cholesterol in human fibroblasts and its absence in homozygous familial hypercholesterolemia.

  1974cited by this paper
• Hyperlipidemia in coronary heart disease. II. Genetic analysis of lipid levels in 176 families and delineation of a new inherited disorder, combined hyperlipidemia.

  1973cited by this paper
• Cofactor activity of protein components of human very low density lipoproteins in the hydrolysis of triglycerides by lipoproteins lipase from different sources.

  1973cited by this paper
• Familial combined hyperlipoproteinemia: studies in 91 adults and 95 children from 33 kindreds.

  1973cited by this paper
• Evidence for a common, saturable, triglyceride removal mechanism for chylomicrons and very low density lipoproteins in man.

  1973cited by this paper
• Characterization of subfractions of triglyceride-rich lipoproteins separated by gel chromatography from blood plasma of normolipemic and hyperlipemic humans.

  1972cited by this paper
• Influence of Obesity on the Relationship Between Insulin and Triglyceride Levels in Endogenous Hypertriglyceridemia

  1971cited by this paper
• Tissue lipoprotein lipase in normal individuals and in individuals with exogenous hypertriglyceridemia and the relationship of this enzyme to assimilation of fat.

  1967cited by this paper
• Idiopathic hyperlipemia: metabolic studies in an affected family.

  1960cited by this paper

• Rôle des cellules de Kupffer et du microbiote intestinal dans les hépatopathies métaboliques

  2015cites this paper
• [Lipoprotein lipase: a multifunctional enzyme in lipoprotein metabolism].

  1996cites this paper