Inhibition of protein kinase C βII downregulates tristetraprolin expression in activated macrophages

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Inflammation Research

• Publication date

  2008-05-05

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1007/s00011-007-7122-2PMID 18594783
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Salbutamol increases tristetraprolin expression in macrophages.

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• Posttranslational Regulation of Tristetraprolin Subcellular Localization and Protein Stability by p38 Mitogen-Activated Protein Kinase and Extracellular Signal-Regulated Kinase Pathways

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• Inhibition of classical PKC isoenzymes downregulates STAT1 activation and iNOS expression in LPS‐treated murine J774 macrophages

  2006influential reference
• Down-Regulation of Tristetraprolin Expression Results in Enhanced IL-12 and MIP-2 Production and Reduced MIP-3α Synthesis in Activated Macrophages

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  2005cited by this paper
• Inhibition of tristetraprolin expression by dexamethasone in activated macrophages.

  2005cited by this paper
• Tristetraprolin Regulates the Expression of the Human Inducible Nitric-Oxide Synthase Gene

  2005cited by this paper
• Protein kinase C isozymes as potential targets for anticancer therapy.

  2004cited by this paper
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  2004cited by this paper
• The Stability of Tristetraprolin mRNA Is Regulated by Mitogen-activated Protein Kinase p38 and by Tristetraprolin Itself*

  2004cited by this paper
• Protein kinase C epsilon: a new target to control inflammation and immune-mediated disorders.

  2004cited by this paper
• Protein kinase C and beyond

  2004cited by this paper
• Emerging and diverse roles of protein kinase C in immune cell signalling.

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• Variations of human adrenomedullin gene and its relation to cardiovascular diseases.

  2003cited by this paper
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  2003cited by this paper
• Post‐transcriptional regulation of gene expression by degradation of messenger RNAs

  2003cited by this paper
• Expression and purification of recombinant tristetraprolin that can bind to tumor necrosis factor-alpha mRNA and serve as a substrate for mitogen-activated protein kinases.

  2003cited by this paper
• c-Jun NH2-terminal kinase inhibitor anthra(1,9-cd)pyrazol-6(2H)-one reduces inducible nitric-oxide synthase expression by destabilizing mRNA in activated macrophages.

  2003cited by this paper
• Protein kinase C beta (PKC beta): normal functions and diseases.

  2002cited by this paper
• Mitogen-Activated Protein Kinase p38 Controls the Expression and Posttranslational Modification of Tristetraprolin, a Regulator of Tumor Necrosis Factor Alpha mRNA Stability

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• HuR and mRNA stability

  2001cited by this paper
• Tristetraprolin and other CCCH tandem zinc-finger proteins in the regulation of mRNA turnover.

  2001cited by this paper
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  1999cited by this paper
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  1999cited by this paper
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  1998cited by this paper
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  1998cited by this paper
• Feedback inhibition of macrophage tumor necrosis factor-alpha production by tristetraprolin.

  1998cited by this paper
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  1998cited by this paper
• Stimulation of P2Y-purinoceptors on astrocytes results in immediate early gene expression and potentiation of neuropeptide action.

  1998cited by this paper
• Bone marrow transplantation reproduces the tristetraprolin-deficiency syndrome in recombination activating gene-2 (-/-) mice. Evidence that monocyte/macrophage progenitors may be responsible for TNFalpha overproduction.

  1997cited by this paper
• A pathogenetic role for TNF alpha in the syndrome of cachexia, arthritis, and autoimmunity resulting from tristetraprolin (TTP) deficiency.

  1996cited by this paper
• Activation of Protein Kinase C in Human Uterine Smooth Muscle Induces connexin-43 Gene Transcription through an AP-1 Site in the Promoter Sequence*

  1996cited by this paper
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  1996cited by this paper
• A carboxy-terminal deletion mutant of protein kinase C beta II inhibits insulin-stimulated 2-deoxyglucose uptake in L6 rat skeletal muscle cells.

  1996cited by this paper
• Promoter Analysis of Zfp-36, the Mitogen-inducible Gene Encoding the Zinc Finger Protein Tristetraprolin (*)

  1995cited by this paper
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