Occurrence of haemophagocytic lymphohistiocytosis at less than 1 year of age: analysis of 96 patients

No abstract is available for this paper.

• Publication year

  2005

• Venue

  European Journal of Pediatrics

• Publication date

  2005-02-25

• Fields of study

  Medicine

• Identifiers
  DOI 10.1007/s00431-005-1636-9PMID 15731905
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Identification of novel MUNC13-4 mutations in familial haemophagocytic lymphohistiocytosis and functional analysis of MUNC13-4-deficient cytotoxic T lymphocytes

  2004cited by this paper
• CNS Disease as the Main Manifestation of Hemophagocytic Lymphohistiocytosis in Two Children

  2004cited by this paper
• Neonatal herpes simplex virus infection

  2004cited by this paper
• Chronic active Epstein-Barr virus infection associated with mutations in perforin that impair its maturation.

  2004cited by this paper
• Munc13-4 is essential for cytolytic granules fusion and is mutated in a form of familial hemophagocytic lymphohistiocytosis (FHL3).

  2003cited by this paper
• Macrophage activation syndrome and reactive hemophagocytic lymphohistiocytosis: the same entities?

  2003influential reference
• Characteristic perforin gene mutations of haemophagocytic lymphohistiocytosis patients in Japan

  2003influential reference
• Clinical features and treatment strategies of Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis.

  2002influential reference
• Low natural killer activity and central nervous system disease as a high‐risk prognostic indicator in young patients with hemophagocytic lymphohistiocytosis

  2002cited by this paper
• Haemophagocytic lymphohistiocytosis: proposal of a diagnostic algorithm based on perforin expression

  2002cited by this paper
• Perforin defects of primary haemophagocytic lymphohistiocytosis in Japan

  2002cited by this paper
• Functional consequences of perforin gene mutations in 22 patients with familial haemophagocytic lymphohistiocytosis

  2002cited by this paper
• Biology and treatment of familial hemophagocytic lymphohistiocytosis: importance of perforin in lymphocyte-mediated cytotoxicity and triggering of apoptosis.

  2002influential reference
• Pathogenesis of haemophagocytic lymphohistiocytosis

  2001cited by this paper
• No mutations of SAP/SH2D1A/DSHP and perforin genes in patients with Epstein‐Barr virus‐associated hemophagocytic syndrome in Japan

  2001influential reference
• Prognosis for neonates with enterovirus hepatitis and coagulopathy.

  2001cited by this paper
• Advances in the management of hemophagocytic lymphohistiocytosis.

  2000cited by this paper
• Perforin gene defects in familial hemophagocytic lymphohistiocytosis.

  1999cited by this paper
• Intermittent hemophagocytic lymphohistiocytosis is a regular feature of lysinuric protein intolerance.

  1999cited by this paper
• Hemophagocytic Syndrome Presenting as Acute Hepatic Failure in Two Infants: Clinical Overlap with Neonatal Hemochromatosis

  1999cited by this paper
• Localization of a gene for familial hemophagocytic lymphohistiocytosis at chromosome 9q21.3-22 by homozygosity mapping.

  1999cited by this paper
• Enterovirus‐associated haemophagocytic syndrome in a neonate

  1998cited by this paper
• Multiple sulphatase deficiency and haemophagocytic syndrome

  1998cited by this paper
• Differential diagnosis of hemophagocytic syndrome: underlying disorders and selection of the most effective treatment.

  1997cited by this paper
• HLH-94: a treatment protocol for hemophagocytic lymphohistiocytosis. HLH study Group of the Histiocyte Society.

  1997cited by this paper
• Hemophagocytic lymphohistiocytosis. Report of 122 children from the International Registry. FHL Study Group of the Histiocyte Society.

  1996cited by this paper
• DIAGNOSTIC GUIDELINES FOR HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS

  1991cited by this paper
• Diagnostic guidelines for hemophagocytic lymphohistiocytosis. The FHL Study Group of the Histiocyte Society.

  1991cited by this paper
• Haemophagocytosis in hereditary fructose intolerance: a diagnostic dilemma

  1990cited by this paper
• Acute hemorrhagic, hepatic, and neurologic manifestations in juvenile rheumatoid arthritis: possible relationship to drugs or infection.

  1985influential reference
• Familial hemophagocytic lymphohistiocytosis

  1983cited by this paper
• Neonatal Herpes Simplex Virus Infection

  1975cited by this paper
• Hemophagocytic Lymphohistiocytosis and Their Family Members Perforin Expression in Cytotoxic Lymphocytes from Patients With

  year unknowncited by this paper

• The immunogenetic basis of severe herpes simplex infections in neonates and children: a review

  2025cites this paper
• Dengue-Associated Hemophagocytic Lymphohistiocytosis: A Diagnostic and Therapeutic Challenge

  2025cites this paper
• Infectious Triggers of Cytokine Storm Syndromes: Herpes Virus Family (Non-EBV).

  2024cites this paper
• Cytokine Storm Syndrome Associated with Hemorrhagic Fever and Other Viruses.

  2024cites this paper
• Congenital Echovirus 11 Infection in a Neonate

  2023cites this paper
• Dengue Fever Complicated with Hemophagocytic Lymphohistiocytosis: A Case Report of Resolution with Steroid-Sparing Supportive Care

  2023cites this paper
• Epidemiology and Outcomes of Neonatal Hemophagocytic Lymphohistiocytosis

  2022cites this paper
• Prolonged fever and hyperferritinaemia: a puzzling diagnosis of neonatal herpes simplex virus infection during COVID-19 pandemic

  2021cites this paper
• Virus‐triggered secondary hemophagocytic lymphohistiocytosis

  2021cites this paper
• Genetic diseases predisposing to HLH

  2020cites this paper
• Adult-Onset Still’s Disease Complicated with Haemophagocytic Lymphohistiocytosis (HLH): A Case Report

  2020cites this paper
• Cytokine Storm Syndrome

  2019influential citation
• Familial Hemophagocytic Lymphohistiocytosis Type 3: Early Disease Onset and Unusual Manifestation in Sibling Cases

  2019cites this paper
• A Rare and Fatal Complication of a Self-Limiting Infection: A Case Report on Dengue Associated Hemophagocytic Lymphohistiocytosis

  2019cites this paper
• Prognostic factors for survival of herpes simplex virus-associated hemophagocytic lymphohistiocytosis

  2019cites this paper
• Is coronary arteritis a feature in secondary haemophagocytic lymphohistiocytosis?

  2018cites this paper
• Macrophage Activation Syndrome

  2018cites this paper
• Developmental and Inherited Liver Disease

  2018cites this paper
• Neonatal Adenovirus Infection Complicated by Hemophagocytic Lymphohistiocytosis Syndrome

  2018cites this paper
• A nine-month-old-boy with Atypical Hemophagocytic Lymphohistiocytosis

  2017cites this paper
• A case report and literature review

  2017cites this paper
• Secondary haemophagocytic lymphohistiocytosis triggered by postnatally acquired cytomegalovirus infection in a late preterm infant

  2017cites this paper
• Hemophagocytic Lymphohistiocytosis, Secondary

  2017cites this paper
• Hyperferritinemic Sepsis: An Opportunity for Earlier Diagnosis and Intervention?

  2016cites this paper
• Wolman disease in patients with familial hemophagocytic lymphohistiocytosis (FHL) negative mutations

  2016cites this paper
• 噬血细胞性淋巴组织细胞增生症患儿及其家系穿孔素和颗粒酶B的表达

  2016cites this paper
• Familial hemophagocytic lymphohistiocytosis in two Saudi siblings.

  2015cites this paper
• Macrophage Activation Syndrome.

  2015cites this paper
• Case 2: A 7-Day-Old African American Boy With Fever, Poor Feeding, and Lethargy

  2015cites this paper
• Screening Hepatoblastoma in Beckwith-Wiedemann Syndrome: A Complex Issue.

  2015cites this paper
• Hemophagocytic Lymphohistiocytosis Due to Rickettsia Japonica in a 3-Month-old Infant.

  2015cites this paper
• Optimal timing of umbilical cord clamping: Is the debate settled? Part 2 of 2: Evidence in preterm and term infants, alternatives, and unanswered questions

  2015cites this paper
• Massive Ferritin Elevation in Neonatal Herpes Simplex Virus Infection: Hemophagocytic Lymphohistiocytosis or Herpes Simplex Virus Alone?

  2015influential citation
• A 6-Year-Old Girl With Undiagnosed Hemophagocytic Lymphohistiocytosis and Takotsubo Cardiomyopathy: A Case Report and Review of the Literature

  2014cites this paper
• Acute liver dysfunction as a presentation of haemophagocytic lymphohistiocytosis.

  2014cites this paper
• Hemophagocytic Lymphohistiocytosis Associated with Cytomegalovirus Infection in an Immunocompetent Infant: A Diagnostic and Therapeutic Challenge!

  2014cites this paper
• Hemophagocytic lymphohistiocytosis associated with viral infections: Diagnostic challenge and therapeutic dilemma

  2014cites this paper
• Diagnostic evaluation of patients with suspected haemophagocytic lymphohistiocytosis

  2013influential citation
• Hemophagocytic lymphohistiocytosis mimicking surgical symptoms and complications: lessons learned from four cases.

  2013cites this paper
• Debate around infection-dependent hemophagocytic syndrome in paediatrics

  2013cites this paper
• Association of Nonimmune Hydrops Fetalis With Familial Hemophagocytic Lymphohistiocytosis in Identical Twin Neonates With Perforin His222Arg (c665A>G) Mutation

  2013cites this paper
• Hemophagocytic Lymphohistiocytosis, Familial

  2013cites this paper
• Infection Associated Hemophagocytic Lymphohistiocytosis: A Case Report.

  2013cites this paper
• [Hemophagocytic syndrome after kidney transplant in a patient with hereditary nephritis. Report of one case].

  2013cites this paper
• Hemophagocytic lymphohistiocytosis in a newborn infant born to a mother with Sjögren syndrome antibodies

  2013cites this paper
• Severe Lactic Acidosis in an Infant with Haemophagocytic Lymphohistiocytosis

  2012cites this paper
• Severe Lactic Acidosis in an Infant with Haemophagocytic Lymphohistiocytosis

  2012cites this paper
• with adult-onset familial hemophagocytic lymphohistiocytosis Hypomorphic mutations in PRF1, MUNC13-4, and STXBP2 are associated

  2012cites this paper
• [Pneumonia due to adenovirus type 7: a case report in a healthy infant].

  2011cites this paper
• Molecular study of the perforin gene in familial hematological malignancies

  2011cites this paper
• Familial Hemophagocytic Lymphohistiocytosis in the Neonate

  2011cites this paper
• Clinical studies of hemophagocytic lymphohistiocytosis

  2011cites this paper
• Hypomorphic mutations in PRF1, MUNC13-4, and STXBP2 are associated with adult-onset familial HLH.

  2011cites this paper
• Developmental abnormalities and liver disease in childhood

  2011cites this paper
• PRF1 gene mutation in a Saudi patient with haemophagocytic lymphohistiocytosis

  2010cites this paper
• Helicobacter pylori infection in children: association with giardiasis

  2010cites this paper
• Macrophage Activation Syndrome in Autoimmune Disease

  2010cites this paper
• Viral infections associated with haemophagocytic syndrome

  2010cites this paper
• Neonatal Enteroviral Sepsis/Meningoencephalitis and Hemophagocytic Lymphohistiocytosis: Diagnostic Challenges

  2010influential citation
• Determination of optimum incubation time for release of bacteria from sputum of patients with cystic fibrosis using dithiothreitol (Sputasol)

  2010cites this paper
• Fatal histiocytic proliferative disorders in paediatric HIV infection with cytomegalovirus end‐organ disease

  2009cites this paper
• A Case of Early Neonatal Fulminant Liver Failure and Haemophagocytic Lymphohistiocytosis

  2009cites this paper
• Mutations in the perforin gene in children with hemophagocytic lymphohistiocytosis.

  2009cites this paper
• Neonatal onset hemophagocytic lymphohistiocytosis in a premature infant

  2009cites this paper
• Characteristics of hemophagocytic lymphohistiocytosis in neonates: a nationwide survey in Japan.

  2009cites this paper
• Hemophagocytic Lymphohistiocytosis and Macrophage Activation Syndrome

  2008cites this paper
• Infections associated with haemophagocytic syndrome

  2007cites this paper
• A haemophagocytic lymphohistiocytosis (HLH)-like picture following breastmilk transmitted cytomegalovirus infection in a preterm infant

  2007cites this paper
• Severe bacteria‐associated hemophagocytic lymphohistiocytosis in an extremely premature infant

  2007cites this paper
• Perforin gene mutations in adult-onset hemophagocytic lymphohistiocytosis.

  2007cites this paper
• Enterovirus-associated hemophagocytic syndrome in children with malignancy: report of three cases and review of the literature

  2007cites this paper
• Perforin-mediated target-cell death and immune homeostasis

  2006cites this paper
• Mutations of perforin and Munc13‐4 do not mark HLH by NK defects

  2006cites this paper
• Perforin and granzymes have distinct roles in defensive immunity and immunopathology.

  2006cites this paper
• Aberrant maturation of mutant perforin underlies the clinical diversity of hemophagocytic lymphohistiocytosis.

  2005cites this paper
• Biomedical Science in Brief.

  2004cites this paper