Production of the main surface antigen of Toxoplasma gondii in tobacco leaves and analysis of its antigenicity and immunogenicity

No abstract is available for this paper.

• Publication year

  2005

• Venue

  Molecular Biotechnology

• Publication date

  2005-05-01

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1385/MB:30:1:041PMID 15805575
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  1997influential reference
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