Differential effects of interleukin 2 receptor-targeted therapy on heart and kidney allografts in rats. Depression of effectiveness of ART-18 monoclonal antibody treatment by uremia.

No abstract is available for this paper.

• Publication year

  1990

• Venue

  Transplantation

• Publication date

  1990-06-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1097/00007890-199006000-00019PMID 2113725
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Agonistic and antagonistic interactions of anti-interleukin 2 receptor monoclonal antibodies in rat recipients of cardiac allografts.

  1989cited by this paper
• Mechanisms maintaining antibody-induced enhancement of allografts. II. Mediation of specific suppression by short lived CD4+ T cells.

  1989cited by this paper
• Mechanism of action of anti-IL-2R monoclonal antibodies. ART-18 prolongs cardiac allograft survival in rats by elimination of IL-2R+ mononuclear cells.

  1989cited by this paper
• Anti-interleukin-2 receptor monoclonal antibody therapy in rats: comparison of the effector mechanisms mediated by variant murine isotypes.

  1989cited by this paper
• Interleukin 2 receptor-targeted therapy--rationale and applications in organ transplantation.

  1988cited by this paper
• Anti-interleukin 2 receptor monoclonal antibodies spare phenotypically distinct T suppressor cells in vivo and exert synergistic biological effects

  1988cited by this paper
• LACK OF CORRELATION BETWEEN THE INDUCTION OF DONOR CLASS I AND CLASS II MAJOR HISTOCOMPATIBILITY COMPLEX ANTIGENS AND GRAFT REJECTION

  1988cited by this paper
• THE ROLE OF CLASS I AND CLASS II MHC ANTIGENS IN THE REJECTION OF VASCULARIZED HEART ALLOGRAFTS IN MICE

  1987cited by this paper
• Prolonged survival of actively enhanced rat renal allografts despite accelerated cellular infiltration and rapid induction of both class I and class II MHC antigens

  1987cited by this paper
• Identification of IL 2R+ T cells and macrophages within rejecting rat cardiac allografts, and comparison of the effects of treatment with anti-IL 2R monoclonal antibody or cyclosporin.

  1987cited by this paper
• Two phenotypically distinct populations of T cells have suppressor capabilities simultaneously in the maintenance phase of immunologic enhancement.

  1987cited by this paper
• W3/25+ T cells mediate the induction of immunologic unresponsiveness in enhanced rat recipients of cardiac allografts.

  1987cited by this paper
• Four epitopes on the rat 55‐kDa subunit of the interleukin 2 receptor as defined by newly developed mouse anti‐rat interleukin 2 receptor monoclonal antibodies

  1987cited by this paper
• DETAILED ANALYSIS AND DEMONSTRATION OF DIFFERENCES IN THE KINETICS OF INDUCTION OF CLASS I AND CLASS II MAJOR HISTOCOMPATIBILITY COMPLEX ANTIGENS IN REJECTING CARDIAC AND KIDNEY ALLOGRAFTS IN THE RAT

  1986cited by this paper
• Therapy with monoclonal antibody to interleukin 2 receptor spares suppressor T cells and prevents or reverses acute allograft rejection in rats.

  1986cited by this paper
• Suppressor T cells in allogeneic models.

  1986cited by this paper
• Suppressor cells and immunoregulation.

  1984cited by this paper
• FUNCTION AND MIGRATION OF SUPPRESSOR LYMPHOCYTES FROM CYCLOSPORINE‐TREATED HEART GRAFT RECIPIENTS

  1983cited by this paper
• Antigenic and Immunogenic Components in Rat Liver

  1983cited by this paper
• The characteristics of a monoclonal antibody that binds specifically to rat T lymphoblasts and inhibits IL 2 receptor functions.

  1983cited by this paper
• Relative vulnerability of isolated pancreatic islets, parathyroid, and skin allografts to cellular and humoral immunity.

  1979cited by this paper
• Immune system to uremia.

  1976cited by this paper
• Acute rejection of skin and heart allografts in rats matched at the major rat histocompatibility locus.

  1969cited by this paper
• Allografts in genetically defined rats: difference in survival between kidney and skin.

  1969cited by this paper

• Failure of treatment with interleukin-2 receptor-specific monoclonal antibody in acute coxsackievirus B3 myocarditis in mice

  2007cites this paper
• Nitric Oxide in Transplant Rejection and Anti-Tumor Defense

  1998cites this paper
• Allograft Rejection - Fact and Fancy

  1998cites this paper
• Potential of Anti-Interleukin-2 Receptor Monoclonal Antibodies in Solid Organ Transplantation

  1997cites this paper
• The Clinical and Experimental Use of Monoclonal Antibodies to the IL-2 Receptor

  1995cites this paper
• Vorbehandlung mit α/β-TCR gerichteter monoklonaler Antikörper (mAb R73)-Therapie induziert langfristiges Transplantatüberleben nach Nieren- und Herztransplantation in der Ratte

  1994cites this paper
• Vorbehandlung mit a / ß-TCR gerichteter monoklonaler Antikörper (mAb R73)-Therapie induziert langfristiges Transplantatüberleben nach Nieren- und Herztransplantation in der Ratte* Pretreatment of Rat Renal and Cardiac Allograft Recipients Using afß-TCR Directed Monoclonal Antibody Therapy (mAb R73)

  1994cites this paper
• Blocking of mononuclear cell accumulation, cytokine production, and endothelial activation within rat cardiac allografts by CD4 monoclonal antibody therapy.

  1992cites this paper
• Tumor necrosis factor production during human renal allograft rejection is associated with depression of plasma protein C and free protein S levels and decreased intragraft thrombomodulin expression

  1992cites this paper
• Altered expression of HLA antigens and CD16 Fc receptors on leukocytes of alcoholic subjects and uremic patients.

  1991cites this paper
• SYNERGY BETWEEN CYCLOSPORINE AND ANTI‐IL-2 RECEPTOR MONOCLONAL ANTIBODIES IN RATS: FUNCTIONAL STUDIES OF HEART AND KIDNEY ALLOGRAFTS

  1991cites this paper
• TNF as a mediator of cardiac transplant rejection, including effects on the intragraft protein C/protein S/thrombomodulin pathway.

  1991cites this paper
• Recognition of self within self: specific lymphocyte positioning and the extracellular matrix.

  1991cites this paper
• The mechanism of synergistic interaction between anti-interleukin 2 receptor monoclonal antibody and cyclosporine therapy in rat recipients of organ allografts.

  1990cites this paper