Prevention of 7-ketocholesterol-induced mitochondrial damage and cell death by calmodulin inhibition.

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Brain Research

• Publication date

  2007-03-16

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1016/J.BRAINRES.2006.12.041PMID 17224136
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Characterization of phenothiazine-induced apoptosis in neuroblastoma and glioma cell lines

  2007cited by this paper
• Oxysterols and Alzheimer's disease

  2006cited by this paper
• Oxidation of Cholesterol by Amyloid Precursor Protein and β-Amyloid Peptide*

  2005cited by this paper
• Oxidation of cholesterol by amyloid precursor protein and beta-amyloid peptide.

  2005cited by this paper
• 7-Ketocholesterol induces reversible cytochrome c release in smooth muscle cells in absence of mitochondrial swelling.

  2004cited by this paper
• Phenothiazines suppress proliferation and induce apoptosis in cultured leukemic cells without any influence on the viability of normal lymphocytes

  2004cited by this paper
• Involvement of a calcium-dependent dephosphorylation of BAD associated with the localization of Trpc-1 within lipid rafts in 7-ketocholesterol-induced THP-1 cell apoptosis

  2004cited by this paper
• Trojan horse-like behavior of a biologically representative mixture of oxysterols.

  2004cited by this paper
• Specific modulation of calmodulin activity induces a dramatic production of superoxide by alveolar macrophages

  2004cited by this paper
• The Mitochondrial Death Pathway and Cardiac Myocyte Apoptosis

  2004cited by this paper
• Oxidative stress in Parkinson's disease

  2003cited by this paper
• Calcium signaling and apoptosis.

  2003cited by this paper
• Phosphorylation of calmodulin. Functional implications.

  2002cited by this paper
• Analysis of oxidative processes and of myelin figures formation before and after the loss of mitochondrial transmembrane potential during 7beta-hydroxycholesterol and 7-ketocholesterol-induced apoptosis: comparison with various pro-apoptotic chemicals.

  2002cited by this paper
• Mitochondrial reactive oxygen species in cell death signaling.

  2002cited by this paper
• Ca2+/Calmodulin-dependent Protein Kinase II Is Required for Microcystin-induced Apoptosis*

  2002cited by this paper
• Nifedipine Prevents Apoptosis of Endothelial Cells Induced By Oxidized Low-density Lipoproteins

  2002cited by this paper
• Calcium and oxidative stress: from cell signaling to cell death.

  2002cited by this paper
• Flavonoids protect neurons from oxidized low-density-lipoprotein-induced apoptosis involving c-Jun N-terminal kinase (JNK), c-Jun and caspase-3.

  2001cited by this paper
• Arachidonate metabolism and the signaling pathway of induction of apoptosis by oxidized LDL/oxysterol.

  2001cited by this paper
• Superoxide radical-initiated apoptotic signalling pathway in selenite-treated HepG(2) cells: mitochondria serve as the main target.

  2001cited by this paper
• Triggering and modulation of apoptosis by oxidative stress.

  2000cited by this paper
• Role of the mitochondrial membrane permeability transition (MPT) in rotenone-induced apoptosis in liver cells.

  2000cited by this paper
• 25-Hydroxycholesterol activates a cytochrome c release-mediated caspase cascade.

  2000cited by this paper
• Oxidized Low‐Density Lipoprotein Induces Neuronal Death

  1999cited by this paper
• The role of glutathione in the regulation of apoptosis

  1999cited by this paper
• The mitochondrial permeability transition pore and its role in cell death.

  1999cited by this paper
• Nitric oxide and mitochondrial respiration.

  1999cited by this paper
• Ca2+-induced apoptosis through calcineurin dephosphorylation of BAD.

  1999cited by this paper
• Etiology and pathogenesis of Parkinson's disease.

  1999cited by this paper
• Oxidized lipoproteins may play a role in neuronal cell death in Alzheimer disease.

  1998cited by this paper
• Glutathione is implied in the control of 7‐ketocholesterol‐induced apoptosis, which is associated with radical oxygen species production

  1998cited by this paper
• Catecholamines Potentiate Amyloid β-Peptide Neurotoxicity: Involvement of Oxidative Stress, Mitochondrial Dysfunction, and Perturbed Calcium Homeostasis

  1998cited by this paper
• The calmodulin antagonist trifluoperazine in transient focal brain ischemia in rats. Anti-ischemic effect and therapeutic window.

  1997cited by this paper
• Oxidized low density lipoprotein caused CNS neuron cell death.

  1997cited by this paper
• Calmodulin‐dependent protein kinase II mediates signal transduction in apoptosis

  1997cited by this paper
• Increase in gamma-glutamyltransferase by glutathione depletion in rat type II pneumocytes.

  1997cited by this paper
• Modulation of the Mitochondrial Permeability Transition Pore by Pyridine Nucleotides and Dithiol Oxidation at Two Separate Sites (*)

  1996cited by this paper
• A specific inhibitor of calcium/calmodulin-dependent protein kinase-II provides neuroprotection against NMDA- and hypoxia/hypoglycemia-induced cell death

  1995cited by this paper
• Mechanisms of nitric oxide-mediated neurotoxicity in primary brain cultures

  1993cited by this paper
• The pathogenesis of atherosclerosis: a perspective for the 1990s

  1993cited by this paper
• Induction of apoptosis in cultured hepatocytes and in regressing liver by transforming growth factor beta 1.

  1992cited by this paper
• Occurrence of lipid oxidation products in foods.

  1986cited by this paper
• Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays.

  1983cited by this paper
• Sterol metabolism--XLVII. Oxidized cholesterol esters in human tissues.

  1981cited by this paper

• Oxysterol signaling in the central nervous system: cellular mechanisms and implications for neurodegeneration.

  2026cites this paper
• Bis(monoacylglycero)phosphate protects murine RAW 264.7 macrophages against 7-ketocholesterol-induced apoptosis and impaired autophagy.

  2026cites this paper
• Oxysterols in Central and Peripheral Synaptic Communication.

  2024cites this paper
• Novel insights into brain lipid metabolism in Alzheimer's disease: Oligodendrocytes and white matter abnormalities

  2023cites this paper
• Attenuation of 7-ketocholesterol- and 7β-hydroxycholesterol-induced oxiapoptophagy by nutrients, synthetic molecules and oils: potential for the prevention of age-related diseases.

  2021cites this paper
• Influential role of 7- Ketocholesterol in the progression of Alzheimer's disease.

  2021cites this paper
• Oxiapoptophagy: A type of cell death induced by some oxysterols

  2020cites this paper
• Trifluoperazine an Antipsychotic Drug and Inhibitor of Mitochondrial Permeability Transition Protects Cytarabine and Ifosfamide-Induced Neurotoxicity

  2020cites this paper
• Induction of peroxisomal changes in oligodendrocytes treated with 7-ketocholesterol: Attenuation by α-tocopherol.

  2018cites this paper
• 7-Oxygenated cholesterol molecules differentially affect the expression of zonula occludens-1 in vascular smooth muscle cells and monocyte/macrophage cells.

  2018cites this paper
• The beneficial effects of HMG-CoA reductase inhibitors in the processes of neurodegeneration

  2017cites this paper
• Extra virgin olive oil phenolic extracts counteract the pro-oxidant effect of dietary oxidized lipids in human intestinal cells.

  2016cites this paper
• Targeting New Pharmacological Approaches for Alzheimer's Disease: Potential for Statins and Phosphodiesterase Inhibitors.

  2016cites this paper
• Effects of Atorvastatin and Streptozocin on Immunohistochemical Markers in Hippocampus of Male Adult Rats

  2015cites this paper
• Harmful effect of oxysterols in the gut and at systemic level: modulatory activity of olive oil phenolics

  2015cites this paper
• Statins more than cholesterol lowering agents in Alzheimer disease: their pleiotropic functions as potential therapeutic targets.

  2014cites this paper
• Review - Part of the Special Issue: Alzheimer's Disease - Amyloid, Tau and Beyond Statins more than cholesterol lowering agents in Alzheimer disease: Their pleiotropic functions as potential therapeutic targets

  2014cites this paper
• Slow Excitotoxicity in Alzheimer's Disease

  2013cites this paper
• Lipids, Cholesterol, and Oxidized Cholesterol in Alzheimer Amyloid Beta‐Mediated Neurotoxicity

  2013cites this paper
• The metabolism of steroids, toxins and drugs by 11β-hydroxysteroid dehydrogenase 1.

  2012cites this paper
• Protective effects of 27- and 24-hydroxycholesterol against staurosporine-induced cell death in undifferentiated neuroblastoma SH-SY5Y cells.

  2012cites this paper
• Mechanisms of oxysterol-induced carcinogenesis

  2011cites this paper
• Long-term high-dose atorvastatin decreases brain oxidative and nitrosative stress in a preclinical model of Alzheimer disease: a novel mechanism of action.

  2011cites this paper
• erspective holesterol-independent neuroprotective and neurotoxic activities of statins : erspectives for statin use in Alzheimer disease and other age-related eurodegenerative disorders

  2011cites this paper
• Thermo-responsiveness of auto-oxidized cholesterol-containing lipid membranes, observed in real-time

  2011cites this paper
• Cholesterol-independent neuroprotective and neurotoxic activities of statins: perspectives for statin use in Alzheimer disease and other age-related neurodegenerative disorders.

  2011cites this paper
• The effect of oxycholesterols on thermo-induced membrane dynamics.

  2011cites this paper
• Cholesterol and Hydroxycholesterol in the Brain

  2011cites this paper
• Strategies for the Mitigation of Oxysterol-Induced Cytotoxicity

  2011cites this paper
• Dynamic Response of a Cholesterol-containing Model Membrane to Oxidative Stress

  2010cites this paper
• Changes in Brain Cholesterol Metabolome After Excitotoxicity

  2010cites this paper
• Lipid mediators in the nucleus: Their potential contribution to Alzheimer's disease.

  2010cites this paper
• Changes in cholesterol biosynthetic and transport pathways after excitotoxicity

  2010cites this paper
• Methionine sulfoxide reductase B2 is highly expressed in the retina and protects retinal pigmented epithelium cells from oxidative damage.

  2010cites this paper
• Tyrosine Kinase Inhibitor AG126 Reduces 7-Ketocholesterol-Induced Cell Death by Suppressing Mitochondria-Mediated Apoptotic Process

  2010cites this paper
• Cytotoxic effects of oxysterols associated with human diseases: Induction of cell death (apoptosis and/or oncosis), oxidative and inflammatory activities, and phospholipidosis.

  2009cites this paper
• Oxysterols and mechanisms of apoptotic signaling: implications in the pathology of degenerative diseases.

  2009cites this paper
• 25-Hydroxycholesterol induces mitochondria-dependent apoptosis via activation of glycogen synthase kinase-3β in PC12 cells

  2008cites this paper
• Side effects of oxysterols: cytotoxicity, oxidation, inflammation, and phospholipidosis.

  2008cites this paper