Mild hypothermia mitigates post‐ischemic neuronal death following focal cerebral ischemia in rat brain: Immunohistochemical study of Fas, caspase‐3 and TUNEL

No abstract is available for this paper.

• Publication year

  2000

• Venue

  Neuropathology (Kyoto. 1993)

• Publication date

  2000-12-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1111/j.1440-1789.2000.00346.xPMID 11211051
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Morphological consequences of early reperfusion following thrombotic or mechanical occlusion of the rat middle cerebral artery

  2004cited by this paper
• Evolution of Brain Infarction after Transient Focal Cerebral Ischemia in Mice

  2000cited by this paper
• Expression of Fas and Fas Ligand After Experimental Traumatic Brain Injury in the Rat

  2000cited by this paper
• Activation of Fas by FasL induces apoptosis by a mechanism that cannot be blocked by Bcl-2 or Bcl-x(L).

  1999cited by this paper
• Fas/Apo [Apoptosis]-1 and Associated Proteins in the Differentiating Cerebral Cortex: Induction of Caspase-Dependent Cell Death and Activation of NF-κB

  1999cited by this paper
• Inhibition of Interleukin-1β Converting Enzyme Family Proteases (Caspases) Reduces Cold Injury-Induced Brain Trauma and DNA Fragmentation in Mice

  1999cited by this paper
• Intrathecal expression of proteins regulating apoptosis in acute stroke.

  1999cited by this paper
• CD95 Ligand (Fas-L/APO-1L) and Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Mediate Ischemia-Induced Apoptosis in Neurons

  1999cited by this paper
• Fas ligand: a sensor for DNA damage critical in skin cancer etiology.

  1999cited by this paper
• Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis

  1998cited by this paper
• Anti-Fas antibody differentially regulates apoptosis in Fas ligand resistant carcinoma lines via the caspase 3 family of cell death proteases but independently of bcl2 expression.

  1998cited by this paper
• Prolonged Therapeutic Window for Ischemic Brain Damage Caused by Delayed Caspase Activation

  1998cited by this paper
• Fas-mediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/Mort1

  1998cited by this paper
• Fas‐induced DNA fragmentation and proteolysis of nuclear proteins

  1998cited by this paper
• Cytosolic Redistribution of Cytochrome C after Transient Focal Cerebral Ischemia in Rats

  1998cited by this paper
• Activation and Cleavage of Caspase-3 in Apoptosis Induced by Experimental Cerebral Ischemia

  1998cited by this paper
• Overexpression of human glutathione peroxidase protects transgenic mice against focal cerebral ischemia/reperfusion damage.

  1998cited by this paper
• Occurrence of apoptosis following cold injury-induced brain edema in mice.

  1997cited by this paper
• Activation of the CED3/ICE-Related Protease CPP32 in Cerebellar Granule Neurons Undergoing Apoptosis But Not Necrosis

  1997cited by this paper
• Reperfusion following focal cerebral ischemia alters distribution of neuronal cells with DNA fragmentation in mice.

  1997cited by this paper
• Apoptosis and Necrosis after Reversible Focal Ischemia: An in Situ DNA Fragmentation Analysis

  1996cited by this paper
• Sequential activation of ICE-like and CPP32-like proteases during Fas-mediated apoptosis

  1996cited by this paper
• Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice

  1996cited by this paper
• Localization of Fas antigen mRNA induced in postischemic murine forebrain by in situ hybridization.

  1995cited by this paper
• Cerebral Metabolic Rate and Hypothermia: Their Relationship with Ischemic Neurologic Injury

  1995cited by this paper
• Cell‐free reconstitution of Fas‐, UV radiation‐ and ceramide‐induced apoptosis.

  1995cited by this paper
• The Fas death factor

  1995cited by this paper
• Apoptotic DNA fragmentation in the rat cerebral cortex induced by permanent middle cerebral artery occlusion.

  1995cited by this paper
• Requirement of an ICE/CED-3 protease for Fas/APO-1-mediated apoptosis

  1995cited by this paper
• Involvement of an ICE-like protease in Fas-mediated apoptosis

  1995cited by this paper
• Detection of DNA damage induced by apoptosis in the rat brain following incomplete ischemia.

  1995cited by this paper
• Glutamate Release and Free Radical Production Following Brain Injury: Effects of Posttraumatic Hypothermia

  1995cited by this paper
• Fas antigen mRNA induction in postischemic murine brain.

  1994cited by this paper
• Progression from ischemic injury to infarct following middle cerebral artery occlusion in the rat.

  1993cited by this paper
• The use of moderate therapeutic hypothermia for patients with severe head injuries: a preliminary report.

  1993cited by this paper
• Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family.

  1993cited by this paper
• The Significance of Brain Temperature in Focal Cerebral Ischemia: Histopathological Consequences of Middle Cerebral Artery Occlusion in the Rat

  1992cited by this paper
• Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation

  1992cited by this paper
• The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis.

  1991cited by this paper
• Mild Hypothermia Prevents Ischemic Injury in Gerbil Hippocampus

  1990cited by this paper
• The Influence of Mild Body and Brain Hypothermia on Ischemic Brain Damage

  1990cited by this paper
• Impairment of metabolic recovery with increasing periods of middle cerebral artery occlusion in rats.

  1990cited by this paper
• Reduction of delayed neuronal death by inhibition of protein synthesis.

  1990cited by this paper
• Reversible middle cerebral artery occlusion without craniectomy in rats.

  1989cited by this paper
• Effect of mild hypothermia on ischemia-induced release of neurotransmitters and free fatty acids in rat brain.

  1989cited by this paper

• Mild therapeutic hypothermia protects against inflammatory and proapoptotic processes in the rat model of cochlear implant trauma.

  2022cites this paper
• The BE COOL Treatments (Batroxobin, oxygEn, Conditioning, and cOOLing): Emerging Adjunct Therapies for Ischemic Cerebrovascular Disease

  2022cites this paper
• Hypothermic neuroprotection against acute ischemic stroke: The 2019 update

  2019cites this paper
• Therapeutic Hypothermia and Neuroprotection in Acute Neurological Disease.

  2019cites this paper
• Neuroprotective Effects and Mechanisms of Zhenlong Xingnao Capsule in In Vivo and In Vitro Models of Hypoxia

  2019cites this paper
• Pharmacological hypothermia induced neurovascular protection after severe stroke of transient middle cerebral artery occlusion in mice.

  2019cites this paper
• Free Radical Damage in Ischemia-Reperfusion Injury: An Obstacle in Acute Ischemic Stroke after Revascularization Therapy

  2018cites this paper
• Prospective clinical biomarkers of caspase-mediated apoptosis associated with neuronal and neurovascular damage following stroke and other severe brain injuries: Implications for chronic neurodegeneration

  2017cites this paper
• Hypothermia in Stroke Therapy: Systemic versus Local Application

  2017cites this paper
• Hypothermic neuroprotections in the brain of an echolocation bat, Hipposideros terasensis

  2017cites this paper
• Therapeutic hypothermia for stroke: Where to go?

  2015cites this paper
• Effects of Mild and Moderate Hypothemia Therapy on Expression of Cerebral Neuron Apoptosis Related Proteins and Glial Fiber Acidic Protein After Rat Cardio-pulmonary Resuscitation

  2014cites this paper
• Mild hypothermia reduces expression of Fas/FasL and MMP-3 after cerebral ischemia-reperfusion in rats

  2014cites this paper
• Interazione tra Catestatina e fibre Orexinergiche/NMDAergiche in condizioni simil-ischemiche nel criceto ibernante

  2014cites this paper
• Detection and analysis of DNA damage in mouse skeletal muscle in situ using the TUNEL method.

  2014cites this paper
• Postcardiac arrest temperature management: infectious risks

  2014cites this paper
• Mild hypothermia reduces activated caspase-3 up to 1 week after a focal cerebral ischemia induced by endothelin-1 in rats.

  2013cites this paper
• Therapeutic Modulation of Brain Temperature: Relevance of Hypothermia to Inflammatory Changes following Transient Cerebral Ischemia in Rats

  2013cites this paper
• Role of Induced Hypothermia in Thoracoabdominal Aortic Aneurysm Surgery

  2012cites this paper
• The neuroprotective effect of post ischemic brief mild hypothermic treatment correlates with apoptosis, but not with gliosis in endothelin-1 treated rats

  2012cites this paper
• Neuroprotection: lessons from hibernators.

  2012cites this paper
• Tea polyphenols increase X-ray repair cross-complementing protein 1 and apurinic/apyrimidinic endonuclease/redox factor-1 expression in the hippocampus of rats during cerebral ischemia/reperfusion injury

  2012cites this paper
• Molecular Mechanisms Underlying the Neuroprotective Effect of Hypothermia in Cerebral Ischemia

  2012cites this paper
• Protection tissulaire dans l'arrêt circulatoire : du massage cardiaque à la protection pharmacologique. Approche clinique et expérimentale

  2011cites this paper
• Induced Hypothermia in Trauma

  2011cites this paper
• Mild hypothermia improves ischemic brain function via attenuating neuronal apoptosis.

  2011cites this paper
• Moderate low temperature preserves the stemness of neural stem cells and suppresses apoptosis of the cells via activation of the cold-inducible RNA binding protein.

  2010cites this paper
• Mild hypothermia reduces ischemic neuron death via altering the expression of p53 and bcl-2

  2010cites this paper
• In vivo optical imaging of early‐stage apoptosis in mouse brain after transient cerebral ischemia

  2010cites this paper
• Protective effects of mild and moderate hypothermia on cultured neuroblastoma-glioma hybrid NG108-15 cells

  2009cites this paper
• Social contact influences histological and behavioral outcomes following cerebral ischemia.

  2009influential citation
• Effect of Post-Traumatic Mild Hypothermia on Hippocampal Cell Death after Traumatic Brain Injury in Rats

  2009cites this paper
• Protection in Animal Models of Brain and Spinal Cord Injury with Mild to Moderate Hypothermia

  2009cites this paper
• Hypothermic inhibition of apoptotic pathways for combined neurotoxicity of iron and ascorbic acid in differentiated PC12 cells: reduction of oxidative stress and maintenance of the glutathione redox state.

  2009cites this paper
• Cell Death is Associated with Reduced Base Excision Repair During Chronic Alcohol Administration in Adult Rat Brain

  2008cites this paper
• FasL shedding is reduced by hypothermia in experimental stroke

  2008cites this paper
• Postischemic mild hypothermia alleviates hearing loss because of transient ischemia

  2008cites this paper
• Conditions of protection by hypothermia and effects on apoptotic pathways in a rat model of permanent middle cerebral artery occlusion.

  2007cites this paper
• Hypothermia treatment potentiates ERK1/2 activation after traumatic brain injury

  2007cites this paper
• General versus Specific Actions of Mild-Moderate Hypothermia in Attenuating Cerebral Ischemic Damage

  2007cites this paper
• Influence of hypothermia on right atrial cardiomyocyte apoptosis in patients undergoing aortic valve replacement

  2007cites this paper
• Therapeutic hypothermia: neuroprotective mechanisms.

  2007influential citation
• Immunohistochemical characterization of Fas (CD95) and Fas Ligand (FasL/CD95L) expression in the injured brain: relationship with neuronal cell death and inflammatory mediators.

  2007cites this paper
• Hypothermia in animal models of acute ischaemic stroke: a systematic review and meta-analysis.

  2007cites this paper
• GABA-mediated effects of some taurine derivatives injected i.c.v. on rabbit rectal temperature and gross motor behavior

  2006cites this paper
• Postischemic infusion of adrenomedullin protects against ischemic stroke by inhibiting apoptosis and promoting angiogenesis.

  2006cites this paper
• Controlled normothermia during ischemia is important for the induction of neuronal cell death after global ischemia in mouse.

  2006cites this paper
• Kallikrein Protects Against Ischemic Stroke by Inhibiting Apoptosis and Inflammation and Promoting Angiogenesis and Neurogenesis

  2006cites this paper
• Intraischemic mild hypothermia prevents neuronal cell death and tissue loss after neonatal cerebral hypoxia–ischemia

  2006cites this paper
• Moderate hypothermia prevents neural cell apoptosis following spinal cord ischemia in rabbits

  2005cites this paper
• Long‐term effects of hypothermia on neuronal cell death and the concentration of apoptotic proteins after incomplete cerebral ischemia and reperfusion in rats

  2005cites this paper
• Regional expression of constitutive and inducible transcription factors following transient focal ischemia in the neonatal rat: influence of hypothermia.

  2005cites this paper
• Biphasic Cytochrome c Release After Transient Global Ischemia and its Inhibition by Hypothermia

  2005cites this paper
• Post‐ischaemic mild hypothermia inhibits apoptosis in the penumbral region by reducing neuronal nitric oxide synthase activity and thereby preventing endothelin‐1‐induced hydroxyl radical formation

  2005cites this paper
• Mild hypothermia inhibits Fas expression and caspase-8 activation following experimental stroke

  2005cites this paper
• Combination of therapeutic mild hypothermia and delayed fluid resuscitation improved survival after uncontrolled haemorrhagic shock in mechanically ventilated rats.

  2004cites this paper
• Post-ischemic hypothermia-induced tissue protection and diminished apoptosis after neonatal cerebral hypoxia-ischemia.

  2004cites this paper
• Adrenomedullin Gene Delivery Protects Against Cerebral Ischemic Injury by Promoting Astrocyte Migration and Survival

  2004cites this paper
• Vesicular acetylcholine transporter can be a morphological marker for the reinnervation to muscle of regenerating motor axons.

  2004cites this paper
• Mild Postischemic Hypothermia Prolongs the Time Window for Gene Therapy by Inhibiting Cytochrome c Release

  2004cites this paper
• Attenuation of ischemia and/or reperfusion injury during myocardial infarction using mild hypothermia in rats: An immunohistochemical study of Bcl‐2, Bax, Bak and TUNEL

  2004cites this paper
• Modification of apoptosis‐related genes and CD95 signaling in cytokine‐treated astrocytes

  2004cites this paper
• Kallikrein Gene Transfer Protects Against Ischemic Stroke by Promoting Glial Cell Migration and Inhibiting Apoptosis

  2004cites this paper
• Attenuation of nitric oxide synthase isoform expression by mild hypothermia after focal cerebral ischemia: variations depending on timing of cooling.

  2003cites this paper
• Stroke: molecular mechanisms and potential targets for treatment.

  2003cites this paper
• Cellular and molecular events underlying ischemia-induced neuronal apoptosis.

  2003cites this paper
• Effect of resuscitative mild hypothermia on glutamate and dopamine release, apoptosis and ischaemic brain damage in the endothelin‐1 rat model for focal cerebral ischaemia

  2003cites this paper
• Differential effects of lowering culture temperature on mediator release from lipopolysaccharide-stimulated neonatal rat microglia

  2002cites this paper
• Cerebrovascular disease and hypothermia Part II: an experimental approach for ischemic neuronal death

  2002cites this paper
• Pseudomonas Aeruginosa Triggered Apoptosis of Human Epithelial Cells Depends on the Temperature During Infection

  2002cites this paper
• Systemic hypothermia, but not regional gut hypothermia, improves survival from prolonged hemorrhagic shock in rats.

  2002cites this paper
• Effects of mild and moderate hypothermia on apoptosis in neuronal PC12 cells.

  2002cites this paper
• Moderate hypothermia in severe head injuries: the present and the future.

  2002cites this paper
• Apoptotic Activity is Increased in Brain Cortex Infarct after Hypothermic Circulatory Arrest in a Porcine Model

  2002cites this paper
• Iranian Journal of Basic Medical Sciences Mild Hypothermia Reduces Expression of Fas/fasl and Mmp- 3 after Cerebral Ischemia-reperfusion in Rats

  year unknowncites this paper