Natural-killer-cell-based treatment in haematopoietic stem-cell transplantation.

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Baillière's Best Practice & Research: Clinical Haematology

• Publication date

  2006-12-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/J.BEHA.2006.06.004PMID 16997185
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Human KIR2DL5 Is an Inhibitory Receptor Expressed on the Surface of NK and T Lymphocyte Subsets1

  2007cited by this paper
• Ex Vivo Expansion of Cord Blood NK Cell Have In Vivo Efficacy Against Leukemia.

  2007cited by this paper
• CliniMACS® Cell Enrichment Using NKp46 — A Large Scale, Single-Step NK Cell Isolation Method.

  2007cited by this paper
• Expanded Natural Killer Cells for Cellular Therapy of Acute Myeloid Leukemia.

  2007cited by this paper
• NK-Cell Recovery and Immune Reconstitution after Haploidentical Hematopoietic Cell Transplantation Using Either CD34 Selected Grafts and Adoptive NK-Cell Transfer or CD3/CD19 Depleted Grafts: Comparison of Two Strategies for NK Cell Based Immunotherapy.

  2007cited by this paper
• No Job Name

  2007influential reference
• Intensity of HLA class I expression and KIR‐mismatch determine NK‐cell mediated lysis of leukaemic blasts from children with acute lymphatic leukaemia

  2007cited by this paper
• Patients Receiving IL-2 Activated Donor NK Cells Show Lower Incidence of Severe GvHD after Haploidentical SCT.

  2007cited by this paper
• Human natural killer cell development and biology.

  2006cited by this paper
• KIR-incompatible hematopoietic-cell transplantation for poor prognosis infant acute lymphoblastic leukemia.

  2006cited by this paper
• NK cell activating receptors and tumor recognition in humans.

  2006cited by this paper
• Preemptive Immunotherapy with Highly Purified CD56+/CD3− Natural Killer Cells after Haploidentical Stem Cell Transplantation. A Prospective Phase II Study in 2 Centers.

  2006cited by this paper
• A Novel Triple Umbilical Cord Blood Transplant (UCBT) Strategy To Promote NK Cell Immunotherapy (Unit 1) with a Fully Ablative Preparative Regimen Followed by a Double UCBT in Patients with Refractory AML.

  2006cited by this paper
• Enhanced NK Cell Activation, Cytotoxicity and Ex-Vivo Expansion (EvE) of Cryopreserved Cord Blood (CB) Natural Killer (NK) Cells: Potential Role for CB NK Cells in Adoptive Cellular Immunotherapy (ACI).

  2006cited by this paper
• Donor natural killer cell allorecognition of missing self in haploidentical hematopoietic transplantation for acute myeloid leukemia: challenging its predictive value.

  2006cited by this paper
• Human NK cell education by inhibitory receptors for MHC class I.

  2006cited by this paper
• Haploidentical allogeneic hematopoietic cell transplantation in adults with reduced-intensity conditioning and CD3/CD19 depletion: fast engraftment and low toxicity.

  2006cited by this paper
• Activated natural killer cells from patients with acute myeloid leukemia are cytotoxic against autologous leukemic blasts in NOD/SCID mice

  2005cited by this paper
• Donor KIR genotype has a major influence on the rate of cytomegalovirus reactivation following T-cell replete stem cell transplantation.

  2005cited by this paper
• Ligands for natural killer cell-activating receptors are expressed upon the maturation of normal myelomonocytic cells but at low levels in acute myeloid leukemias.

  2005cited by this paper
• Licensing of natural killer cells by host major histocompatibility complex class I molecules

  2005cited by this paper
• Successful adoptive transfer and in vivo expansion of human haploidentical NK cells in patients with cancer.

  2005cited by this paper
• Ex vivo Expansion of Highly Purified NK Cells for Immunotherapy after Haploidentical Stem Cell Transplantation in Children

  2005cited by this paper
• Analysis of the receptor-ligand interactions in the natural killer-mediated lysis of freshly isolated myeloid or lymphoblastic leukemias: evidence for the involvement of the Poliovirus receptor (CD155) and Nectin-2 (CD112).

  2005cited by this paper
• rhG-CSF does not affect the phenotype of adult donor peripheral blood NK cells

  2005cited by this paper
• NK-cell reconstitution after haploidentical hematopoietic stem-cell transplantations: immaturity of NK cells and inhibitory effect of NKG2A override GvL effect.

  2005cited by this paper
• A subset of natural killer cells achieves self-tolerance without expressing inhibitory receptors specific for self-MHC molecules.

  2005cited by this paper
• Leukapheresis for the extraction of monocytes and various lymphocyte subpopulations from peripheral blood: product quality and prediction of the yield using different harvest procedures

  2005cited by this paper
• NK cell recognition.

  2005cited by this paper
• AML patients lacking kir ligand for donor KIR exhibit increased overall survival in HLA-identical sibling transplants

  2004cited by this paper
• Ex vivo expansion of natural killer cells for clinical applications.

  2004cited by this paper
• Recognition of HLA‐A3 and HLA‐A11 by KIR3DL2 is peptide‐specific

  2004cited by this paper
• The beneficial role of inhibitory KIR genes of HLA class I NK epitopes in haploidentically mismatched stem cell allografts may be masked by residual donor-alloreactive T cells causing GVHD.

  2004cited by this paper
• IL-2 activated NK cell immunotherapy of three children after haploidentical stem cell transplantation.

  2004influential reference
• Determinants of Antileukemia Effects of Allogeneic NK Cells 1

  2004cited by this paper
• Enhanced cytotoxicity of allogeneic NK cells with killer immunoglobulin-like receptor ligand incompatibility against melanoma and renal cell carcinoma cells.

  2004cited by this paper
• The impact of donor KIR and patient HLA-C genotypes on outcome following HLA-identical sibling hematopoietic stem cell transplantation for myeloid leukemia.

  2004cited by this paper
• Unravelling natural killer cell function: triggering and inhibitory human NK receptors

  2004cited by this paper
• Purified donor NK-lymphocyte infusion to consolidate engraftment after haploidentical stem cell transplantation

  2004cited by this paper
• Haploidentical vs autologous hematopoietic stem cell transplantation in patients with acute leukemia beyond first remission

  2003cited by this paper
• T‐cell alloreactivity dominates natural killer cell alloreactivity in minimally T‐cell‐depleted HLA‐non‐identical paediatric bone marrow transplantation

  2003cited by this paper
• Natural killer cells and viral infections.

  2003cited by this paper
• Survival advantage with KIR ligand incompatibility in hematopoietic stem cell transplantation from unrelated donors.

  2003cited by this paper
• Donor lymphocyte infusions in adult haploidentical transplant: a dose finding study

  2003cited by this paper
• Purification of human natural killer cells using a clinical-scale immunomagnetic method.

  2003cited by this paper
• The immunobiology of natural killer cells and bone marrow allograft rejection.

  2003cited by this paper
• Alloreactive killer cells: hindrance and help for haematopoietic transplants

  2003cited by this paper
• Large-Scale Generation of Natural Killer Lymphocytes for Clinical Application

  2002cited by this paper
• Evaluation of KIR ligand incompatibility in mismatched unrelated donor hematopoietic transplants. Killer immunoglobulin-like receptor.

  2002cited by this paper
• New aspects of natural-killer-cell surveillance and therapy of cancer

  2002cited by this paper
• Relevance of KIR gene polymorphisms in bone marrow transplantation outcome.

  2002cited by this paper
• What is a natural killer cell?

  2002cited by this paper
• Structure and function of major histocompatibility complex (MHC) class I specific receptors expressed on human natural killer (NK) cells.

  2002cited by this paper
• Donor lymphocyte infusion for relapsed chronic myelogenous leukemia: prognostic relevance of the initial cell dose.

  2002cited by this paper
• KIR: diverse, rapidly evolving receptors of innate and adaptive immunity.

  2002cited by this paper
• Transplants across human leukocyte antigen barriers.

  2002cited by this paper
• Definition of gene content for nine common group B haplotypes of the Caucasoid population: KIR haplotypes contain between seven and eleven KIR genes

  2002cited by this paper
• Natural killer cell receptors: new biology and insights into the graft-versus-leukemia effect.

  2002cited by this paper
• Effectiveness of Donor Natural Killer Cell Alloreactivity in Mismatched Hematopoietic Transplants

  2002cited by this paper
• Randomized trial of CD8+ T-cell depletion in the prevention of graft-versus-host disease associated with donor lymphocyte infusion.

  2002cited by this paper
• Innate immunity against hematological malignancies.

  2002cited by this paper
• Human natural killer cell receptors and co‐receptors

  2001cited by this paper
• A prospective analysis of the pattern of immune reconstitution in a paediatric cohort following transplantation of positively selected human leucocyte antigen‐disparate haematopoietic stem cells from parental donors

  2001cited by this paper
• Genetically haploidentical stem cell transplantation for acute leukemia

  2001cited by this paper
• Megadose transplantation of purified peripheral blood CD34+progenitor cells from HLA-mismatched parental donors in children

  2001cited by this paper
• Activating receptors and coreceptors involved in human natural killer cell-mediated cytolysis.

  2001cited by this paper
• Effect of granulocyte colony-stimulating factor mobilization on phenotypical and functional properties of immune cells.

  2001cited by this paper
• Human natural killer cells: a unique innate immunoregulatory role for the CD56(bright) subset.

  2001cited by this paper
• Allogeneic transplantation across major HLA barriers.

  2001cited by this paper
• Human natural killer cells: a unique innate immunoregulatory role for the CD56bright subset

  2001cited by this paper
• Cellular therapy: exploiting NK cell alloreactivity in transplantation

  2001cited by this paper
• Comparison of single-dose and escalating-dose regimens of donor lymphocyte infusion for relapse after allografting for chronic myeloid leukemia.

  2000cited by this paper
• Increased stem cell dose, as obtained using currently available technology, may not be sufficient for engraftment of haploidentical stem cell transplants

  2000cited by this paper
• Mobilization of NK cells by exercise: downmodulation of adhesion molecules on NK cells by catecholamines.

  2000cited by this paper
• Prevention of graft versus host disease by inactivation of host antigen-presenting cells.

  1999cited by this paper
• A Human Histocompatibility Leukocyte Antigen (HLA)-G–specific Receptor Expressed on All Natural Killer Cells

  1999cited by this paper
• Role of natural killer cell alloreactivity in HLA-mismatched hematopoietic stem cell transplantation.

  1999cited by this paper
• Differential binding to HLA-C of p50-activating and p58-inhibitory natural killer cell receptors.

  1998cited by this paper
• Treatment of high-risk acute leukemia with T-cell-depleted stem cells from related donors with one fully mismatched HLA haplotype.

  1998cited by this paper
• Human diversity in killer cell inhibitory receptor genes.

  1997cited by this paper
• Functionally and structurally distinct NK cell receptor repertoires in the peripheral blood of two human donors.

  1997cited by this paper
• High lytic activity against human leukemia cells after activation of allogeneic NK cells by IL-12 and IL-2.

  1996cited by this paper
• Catecholamines induce alterations of distribution and activity of human natural killer (NK) cells

  1993cited by this paper
• Response of human natural killer (NK) cells to NK cell stimulatory factor (NKSF): cytolytic activity and proliferation of NK cells are differentially regulated by NKSF

  1992cited by this paper
• Immunological changes in young and old adults during brief laboratory stress.

  1991cited by this paper
• Donor leukocyte transfusions for treatment of recurrent chronic myelogenous leukemia in marrow transplant patients.

  1990cited by this paper
• Donor Leukocyte Transfusions for Treatment of Recurrent Chronic Myelogenous Leukemia in Marrow Transplant Patients

  1990cited by this paper
• Biology and clinical relevance of human natural killer cells.

  1990cited by this paper
• A progress report on the treatment of 157 patients with advanced cancer using lymphokine-activated killer cells and interleukin-2 or high-dose interleukin-2 alone.

  1987cited by this paper

• Lymphocytes of Drug Resistant Tuberculosis Patients

  2022cites this paper
• How I treat high-risk acute myeloid leukemia using pre-emptive adoptive cellular immunotherapy.

  2022cites this paper
• Allogeneic natural killer cell therapy

  2022cites this paper
• Recent progress in and challenges in cellular therapy using NK cells for hematological malignancies.

  2020cites this paper
• Development of Automated Separation, Expansion, and Quality Control Protocols for Clinical-Scale Manufacturing of Primary Human NK Cells and Alpharetroviral Chimeric Antigen Receptor Engineering

  2019cites this paper
• Clinical Risk in Apheresis-Derived Cellular Therapy

  2019cites this paper
• Natural Killer Cells as Allogeneic Effectors in Adoptive Cancer Immunotherapy

  2019cites this paper
• Cellular therapy for acute myeloid Leukemia - Current status and future prospects.

  2019cites this paper
• Solubility-enhanced gMYL6 fused with a hexa-lysine tag promotes the cytotoxicity of human NK cells.

  2018cites this paper
• Investigation of a NKG2D-dependent tumor immune escape mechanism of head and neck squamous cell carcinoma and proof of concept of a clinical intervention strategy

  2017cites this paper
• Sweet Is the Memory of Past Troubles: NK Cells Remember.

  2016cites this paper
• Cytotoxic potential of IL‐15‐activated cytokine‐induced killer cells against human neuroblastoma cells

  2016cites this paper
• Strategies before, during, and after hematopoietic cell transplantation to improve T-cell immune reconstitution.

  2016influential citation
• Natural Killer Cells

  2016cites this paper
• The role of KIR2DL3/HLA-C*0802 in Brazilian patients with rheumatoid vasculitis

  2015cites this paper
• Hematopoietic Stem Cell Transplantation: Evolution and Future Perspectives

  2015cites this paper
• Natural Killer Cell Memory.

  2015cites this paper
• Downmodulation of CD16 in Human Primary Regulates the Activation-Induced Membrane-Type 6 Matrix Metalloproteinase

  2014cites this paper
• Interleukin-2-stimulated natural killer cells are less susceptible to mycophenolate mofetil than non-activated NK cells: possible consequences for immunotherapy

  2014cites this paper
• Human natural killer cells acting as phagocytes against Candida albicans and mounting an inflammatory response that modulates neutrophil antifungal activity.

  2014cites this paper
• Natürliche Killerzellen und Leukämiekontrolle

  2013cites this paper
• Cellular mechanism for granulocyte-colony stimulating factor in the prevention of graft-versus-host disease in combined bone marrow and peripheral blood transplantation for hematological malignancies: the composition in collection.

  2013cites this paper
• Pre-emptive immunotherapy with purified natural killer cells after haploidentical SCT: a prospective phase II study in two centers

  2013cites this paper
• Clinical Grade Purification and Expansion of NK Cell Products for an Optimized Manufacturing Protocol

  2013cites this paper
• Immunotherapy of invasive fungal infection in hematopoietic stem cell transplant recipients

  2013cites this paper
• Haploidentical hematopoietic SCT increases graft-versus-tumor effect against renal cell carcinoma

  2013cites this paper
• Natural killer cells: walking three paths down memory lane.

  2013cites this paper
• The role of KIR genes and ligands in leukemia surveillance

  2013cites this paper
• Immunotherapy in invasive fungal infection--focus on invasive aspergillosis.

  2013cites this paper
• Rhizopus oryzae hyphae are damaged by human natural killer (NK) cells, but suppress NK cell mediated immunity.

  2013cites this paper
• NK Cells Downmodulation of CD 16 in Human Primary Regulates the Activation-Induced Membrane-Type 6 Matrix Metalloproteinase

  2013cites this paper
• Clinical-grade purification and expansion of CD56 + CD3 - NK cells for adoptive immunotherapy of solid tumors and leukemia

  2013cites this paper
• Membrane-Type 6 Matrix Metalloproteinase Regulates the Activation-Induced Downmodulation of CD16 in Human Primary NK Cells

  2013cites this paper
• NK cell therapy: targeting disease relapse after hematopoietic stem cell transplantation.

  2012cites this paper
• Hematopoietic stem cell transplantation: a review and recommendations for follow-up care for the general practitioner.

  2012cites this paper
• NK cells: key to success of DC-based cancer vaccines?

  2012cites this paper
• [Immunotherapy with allogeneic NK cells after stem cell transplantation: harnessing a potent "killer" of tumor cells].

  2012cites this paper
• Reply to Bouzani et al

  2012cites this paper
• Immuntherapien mit allogenen NK-Zellen nach Stammzelltransplantation

  2012cites this paper
• Génération de cellules nk et de progéniteurs de cellules nk

  2012cites this paper
• cell therapy : targeting disease relapse after hematopoietic stem cell transplantation

  2012cites this paper
• Study of KIR Expression and HLA Ligands in CD56+ Lymphocytes of Drug Resistant Tuberculosis Patients

  2011cites this paper
• Immunotherapy Against Invasive Fungal Diseases in Stem Cell Transplant Recipients

  2011cites this paper
• IL-2 Stimulated but Not Unstimulated NK Cells Induce Selective Disappearance of Peripheral Blood Cells: Concomitant Results to a Phase I/II Study

  2011cites this paper
• Factors influencing engraftment in HLA-haploidentical/mismatch related transplantation with combined granulocyte-colony stimulating factor-mobilized peripheral blood and bone marrow for patients with leukemia.

  2011cites this paper
• Study of KIR expression and HLA ligands in CD56+ lymphocytes of drug resistant tuberculosis patients.

  2011cites this paper
• Human natural killer cells exhibit direct activity against Aspergillus fumigatus hyphae, but not against resting conidia.

  2011cites this paper
• Clinical-Grade Generation of Active NK Cells from Cord Blood Hematopoietic Progenitor Cells for Immunotherapy Using a Closed-System Culture Process

  2011cites this paper
• Mechanisms of Tumor and Viral Immune Escape from Natural Killer Cell-Mediated Surveillance

  2011cites this paper
• High Log-Scale Expansion of Functional Human Natural Killer Cells from Umbilical Cord Blood CD34-Positive Cells for Adoptive Cancer Immunotherapy

  2010cites this paper
• Natürliche Killerzellen in der Leukämie- und Tumortherapie

  2010cites this paper
• Cellular immunotherapy of cancer.

  2010cites this paper
• Étude des mécanismes d'action de la PhotoChimiothérapie Extra-corporelle chez l'Homme

  2010cites this paper
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  2010cites this paper
• Isolation, culture and propagation of natural killer cells

  2010cites this paper
• Stem cell collection in unmanipulated HLA-haploidentical/mismatched related transplantation with combined granulocyte-colony stimulating factor-mobilised blood and bone marrow for patients with haematologic malignancies: the impact of donor characteristics and procedural settings

  2010cites this paper
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  2010cites this paper
• Antileukemia and antitumor effects of the graft-versus-host disease: a new immunovirological approach.

  2010cites this paper
• Cost and outcome in stem cell collections in HLA-haplo identical/mismatched related transplantation with combined granulocyte-colony stimulating factor-mobilized blood and bone marrow for patients with hematologic malignancies.

  2010cites this paper
• Clinical‐grade purification of natural killer cells in haploidentical hematopoietic stem cell transplantation

  2009cites this paper
• Cancer Chemotherapy and Immune Regulation

  2009cites this paper
• Cellular immune reconstitution and its impact on clinical outcome in children with beta thalassemia major undergoing a matched related myeloablative allogeneic bone marrow transplant.

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• Clinical-grade ex vivo-expanded human natural killer cells up-regulate activating receptors and death receptor ligands and have enhanced cytolytic activity against tumor cells.

  2009cites this paper
• Cancer immunotherapy: will expanding knowledge lead to success in pediatric oncology?

  2008cites this paper
• NK cells recognize and lyse Ewing sarcoma cells through NKG2D and DNAM-1 receptor dependent pathways.

  2008cites this paper
• A pilot study of allogeneic cellular therapy for patients with advanced hematologic malignancies.

  2008cites this paper
• Cellular immune reconstitution after haploidentical transplantation in children.

  2008cites this paper
• Indications and donor selections for allogeneic stem cell transplantation in children with hematologic malignancies.

  2008cites this paper