Comparative proteomic analysis suggests that mitochondria are involved in autosomal recessive polycystic kidney disease

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Proteomics

• Publication date

  2012-08-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1002/pmic.201100590PMID 22718539
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Autosomal dominant polycystic kidney disease.

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  2001cited by this paper
• Apoptosis in polycystic kidney disease: involvement of caspases.

  2000cited by this paper
• Mitochondrial disease in superoxide dismutase 2 mutant mice.

  1999cited by this paper
• Mitochondrial diseases in man and mouse.

  1999cited by this paper
• Characterization of three isoforms of mammalian peroxiredoxin that reduce peroxides in the presence of thioredoxin.

  1999cited by this paper
• Disorders of the Mitochondria

  1998cited by this paper
• Pathogenesis of Autosomal Dominant Polycystic Kidney Disease: Role of Apoptosis

  1998cited by this paper
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  1996cited by this paper
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  1996cited by this paper
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  1996cited by this paper
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  1996cited by this paper
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  1995cited by this paper
• Apoptosis and loss of renal tissue in polycystic kidney diseases.

  1995cited by this paper
• Proliferative activity of cyst epithelium in human renal cystic diseases.

  1995cited by this paper
• Fulminant metanephric apoptosis and abnormal kidney development in bcl-2-deficient mice.

  1995cited by this paper
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  1994cited by this paper
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  1993cited by this paper
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  1993cited by this paper
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  1993cited by this paper
• Molecular abnormalities of a phosphoglycerate kinase variant generated by spontaneous mutation.

  1992cited by this paper
• C-myc as an inducer of polycystic kidney disease in transgenic mice.

  1991cited by this paper
• Prenatal diagnosis by ultrasound in pregnancies at risk for autosomal recessive polycystic kidney disease.

  1990cited by this paper
• Protein folding in mitochondria requires complex formation with hsp60 and ATP hydrolysis

  1989cited by this paper
• [Mitochondrial oxidative phosphorylation in the rat kidney during the perinatal period].

  1987cited by this paper
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  year unknowncited by this paper

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  2018cites this paper
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  2016cites this paper
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