Key Points Terminal maturation of primary murine primitive erythroid precursors is characterized by loss of organelles and anabolic components. Metabolic reprogramming includes depression of mitochondrial metabolism and upregulation of the pentose phosphate pathway and redox metabolism.
Circulating primitive murine erythroblasts undergo complex proteomic and metabolomic changes during terminal maturation
T. Nemkov,P. Kingsley,Monika Dzieciatkowska,Jeffrey Malik,K. McGrath,K. Hansen,Angelo D’Alessandro,J. Palis
Published 2022 in Blood Advances
ABSTRACT
PUBLICATION RECORD
- Publication year
2022
- Venue
Blood Advances
- Publication date
2022-02-09
- Fields of study
Biology, Medicine
- Identifiers
- External record
- Source metadata
Semantic Scholar, PubMed
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