Increasing the accuracy of mass isotopomer analysis through calibration curves constructed using biologically synthesized compounds.

No abstract is available for this paper.

• Publication year

  2009

• Venue

  Journal of Mass Spectrometry

• Publication date

  2009-07-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1002/jms.1583PMID 19370770
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Isotopic non-stationary 13C gluconate tracer method for accurate determination of the pentose phosphate pathway split-ratio in Penicillium chrysogenum.

  2008cited by this paper
• Analysis of 13C labeling enrichment in microbial culture applying metabolic tracer experiments using gas chromatography-combustion-isotope ratio mass spectrometry.

  2008cited by this paper
• GC-EI-TOF-MS analysis of in vivo carbon-partitioning into soluble metabolite pools of higher plants by monitoring isotope dilution after 13CO2 labelling.

  2007cited by this paper
• Mass Isotopomer Analysis of Stable Isotope‐Labeled Palmitoyl‐CoA

  2007cited by this paper
• Accurate assessment of amino acid mass isotopomer distributions for metabolic flux analysis.

  2007cited by this paper
• Methylobacterium salsuginis sp. nov., isolated from seawater.

  2007cited by this paper
• Computational tools for isotopically instationary 13C labeling experiments under metabolic steady state conditions.

  2006cited by this paper
• Experimental design principles for isotopically instationary 13C labeling experiments

  2006cited by this paper
• Pathway Confirmation and Flux Analysis of Central Metabolic Pathways in Desulfovibrio vulgaris Hildenborough using Gas Chromatography-Mass Spectrometry and Fourier Transform-Ion Cyclotron Resonance Mass Spectrometry

  2006cited by this paper
• An Examination of the Carbon Isotope Effects Associated with Amino Acid Biosynthesis

  2006cited by this paper
• Determination of complex isotopomer patterns in isotopically labeled compounds by mass spectrometry.

  2005cited by this paper
• Large-scale 13C-flux analysis reveals mechanistic principles of metabolic network robustness to null mutations in yeast

  2005cited by this paper
• Viewpoint: Carbon isotope effect predictions for enzymes involved in the primary carbon metabolism of plant leaves.

  2005cited by this paper
• From stationary to instationary metabolic flux analysis.

  2005cited by this paper
• Patterns of intramolecular carbon isotopic heterogeneity within amino acids of autotrophs and heterotrophs

  2004cited by this paper
• Responses of theCentral Metabolism in Escherichia coli to PhosphoglucoseIsomerase and Glucose-6-Phosphate DehydrogenaseKnockouts

  2003cited by this paper
• Metabolic flux analysis of Escherichia coli K12 grown on 13C-labeled acetate and glucose using GC-MS and powerful flux calculation method.

  2003cited by this paper
• Systematic quantification of complex metabolic flux networks using stable isotopes and mass spectrometry.

  2003cited by this paper
• Quantification of central metabolic fluxes in the facultative methylotroph methylobacterium extorquens AM1 using 13C‐label tracing and mass spectrometry

  2003cited by this paper
• Ion-trap mass spectrometry used in combination with gas chromatography for high-resolution metabolic flux determination.

  2003cited by this paper
• Non-linearity in the quadrupole detector system: implications for the determination of the 13C mass distribution of an ion fragment.

  2003cited by this paper
• In vivo measurement of fluxes through metabolic pathways: the missing link in functional genomics and pharmaceutical research.

  2003cited by this paper
• 13C isotopomer analysis of glutamate by tandem mass spectrometry.

  2002cited by this paper
• Stoichiometric model for evaluating the metabolic capabilities of the facultative methylotroph Methylobacterium extorquens AM1, with application to reconstruction of C(3) and C(4) metabolism.

  2002cited by this paper
• Metabolic isotopomer labeling systems. Part I: global dynamic behavior.

  2001cited by this paper
• A universal framework for 13C metabolic flux analysis.

  2001cited by this paper
• Elimination of the concentration dependence in mass isotopomer abundance mass spectrometry of methyl palmitate using metastable atom bombardment

  2001cited by this paper
• Application of MALDI-TOF MS to lysine-producing Corynebacterium glutamicum: a novel approach for metabolic flux analysis.

  2001cited by this paper
• GC‐MS Analysis of Amino Acids Rapidly Provides Rich Information for Isotopomer Balancing

  2000cited by this paper
• Mass spectrometry for metabolic flux analysis.

  1999cited by this paper
• Determination of amino acid isotope enrichment using liquid chromatography-mass spectrometry.

  1999cited by this paper
• Isotopomer analysis using GC-MS.

  1999cited by this paper
• Mass isotopomer distribution analysis at eight years: theoretical, analytic, and experimental considerations.

  1999cited by this paper
• 13C-NMR, MS and metabolic flux balancing in biotechnology research

  1998cited by this paper
• Bidirectional reaction steps in metabolic networks: I. Modeling and simulation of carbon isotope labeling experiments.

  1997cited by this paper
• Bidirectional reaction steps in metabolic networks: II. Flux estimation and statistical analysis.

  1997cited by this paper
• Modeling isotopomer distributions in biochemical networks using isotopomer mapping matrices.

  1997cited by this paper
• Applications of mass isotopomer analysis to nutrition research.

  1997cited by this paper
• Correction of 13C mass isotopomer distributions for natural stable isotope abundance.

  1996cited by this paper
• Biosynthetically directed fractional 13C-labeling of proteinogenic amino acids. An efficient analytical tool to investigate intermediary metabolism.

  1995cited by this paper
• Modeling of Isotope Distributions and Intracellular Fluxes in Metabolic Networks Using Atom Mapping Matrices

  1994cited by this paper
• Measurement of 15N enrichment in multiple amino acids and urea in a single analysis by gas chromatography/mass spectrometry.

  1993cited by this paper
• Stable isotope tracer analysis by GC-MS, including quantification of isotopomer effects.

  1992cited by this paper
• The isotopic composition of carbon and nitrogen in individual amino acids isolated from modern and fossil proteins

  1991cited by this paper
• Mass isotopomer analysis: theoretical and practical considerations.

  1991cited by this paper
• A CALIBRATED MEASUREMENT OF THE ATOMIC WEIGHT OF CARBON

  1990cited by this paper
• Stable Carbon Isotope Fractionation by Methanosarcina barkeri during Methanogenesis from Acetate, Methanol, or Carbon Dioxide-Hydrogen

  1987cited by this paper

• Advances in mass spectrometry for metabolomics: Strategies, challenges, and innovations in disease biomarker discovery.

  2024cites this paper
• Central carbon metabolism influences cellulase production in Bacillus licheniformis

  2018cites this paper
• Recent advances in high-throughput 13C-fluxomics.

  2017cites this paper
• Metabolic engineering of Corynebacterium glutamicum for methionine production by removing feedback inhibition and increasing NADPH level

  2016cites this paper
• Isotopic studies of metabolic systems by mass spectrometry: using Pascal's triangle to produce biological standards with fully controlled labeling patterns.

  2014cites this paper
• Determination of isotopic labeling of proteins by precursor ion scanning liquid chromatography/tandem mass spectrometry of derivatized amino acids applied to nuclear magnetic resonance studies.

  2012cites this paper
• A systematic investigation of Escherichia coli central carbon metabolism in response to superoxide stress

  2010cites this paper