Molecular Evidence That in Vivo Isotype Switching Occurs within the Germinal Centers

No abstract is available for this paper.

• Publication year

  1995

• Venue

  Annals of the New York Academy of Sciences

• Publication date

  1995-09-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1111/j.1749-6632.1995.tb55818.xPMID 7486514
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Analysis of somatic mutation in five B cell subsets of human tonsil

  1994cited by this paper
• T cells within germinal centers are specific for the immunizing antigen.

  1993cited by this paper
• Replacement of germ-line epsilon promoter by gene targeting alters control of immunoglobulin heavy chain class switching.

  1993cited by this paper
• A selective defect in IgG2b switching as a result of targeted mutation of the I gamma 2b promoter and exon.

  1993cited by this paper
• Tracing B cell development in human germinal centres by molecular analysis of single cells picked from histological sections.

  1993cited by this paper
• Molecular interactions mediating T-B lymphocyte collaboration in human lymphoid follicles. Roles of T cell-B-cell-activating molecule (5c8 antigen) and CD40 in contact-dependent help.

  1992cited by this paper
• Germinal centres in T-cell-dependent antibody responses.

  1992cited by this paper
• Intraclonal generation of antibody mutants in germinal centres

  1991cited by this paper
• Maturation of the immune response in germinal centers.

  1991cited by this paper
• Two species of human Fc epsilon receptor II (Fc epsilon RII/CD23): tissue-specific and IL-4-specific regulation of gene expression.

  1988cited by this paper
• Two species of human Fcε receptor II (FcεRIICD23): Tissue-specific and IL-4-specific regulation of gene expression

  1988cited by this paper
• Germinal centre B cells: antigen specificity and changes in heavy chain class expression

  1982cited by this paper

• Molecular analysis of immunoglobulin genes reveals frequent clonal relatedness in double monoclonal gammopathies

  2013cites this paper
• Comprehensive Assessment of Potential Multiple Myeloma Immunoglobulin Heavy Chain V-D-J Intraclonal Variation Using Massively Parallel Pyrosequencing

  2012cites this paper
• Regulation of Humoral Immunity by Pim Kinases: A Dissertation

  2011cites this paper
• VU Research Portal Secondary lymphoid organ development

  2009cites this paper
• Hairy cell leukemia: at the crossroad of somatic mutation and isotype switch.

  2004cites this paper
• The association between systemic lupus erythematosus and deficiencies of the complement system.

  2002cites this paper
• Intraclonal homogeneity of clonotypic immunoglobulin M and diversity of nonclinical post-switch isotypes in multiple myeloma: insights into the evolution of the myeloma clone.

  2002cites this paper
• The biology and cytogenetics of multiple myeloma.

  2002cites this paper
• Tumor cells of hairy cell leukemia express multiple clonally related immunoglobulin isotypes via RNA splicing.

  2001cites this paper
• Presence of a population of CD20+, CD38- B lymphocytes with defective proliferative responsiveness in the synovial compartment of patients with rheumatoid arthritis.

  2001cites this paper
• Surface Isotypes and Differentiation Antigens Cell Subsets Defined by the Expression of Identification of Murine Germinal Center B

  2000cites this paper
• Identification of Murine Germinal Center B Cell Subsets Defined by the Expression of Surface Isotypes and Differentiation Antigens1

  2000cites this paper
• Transcription factor B-cell-specific activator protein (BSAP) is differentially expressed in B cells and in subsets of B-cell lymphomas.

  1998cites this paper
• Human germinal center B cells express the apoptosis-inducing genes Fas, c-myc, P53, and Bax but not the survival gene bcl-2

  1996cites this paper
• B-chronic lymphocytic leukemias can undergo isotype switching in vivo and can be induced to differentiate and switch in vitro.

  1996cites this paper