Chronic oral administration of ginseng extract results in behavioral change but has no effects in mice models of affective and anxiety disorders

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Phytotherapy Research

• Publication date

  2007-01-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1002/ptr.2024PMID 17089329
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Impairments of neuroplasticity and cellular resilience in severe mood disorders: implications for the development of novel therapeutics.

  2025cited by this paper
• Identification of anxiolytic ingredients in ginseng root using the elevated plus-maze test in mice.

  2006cited by this paper
• Increased anxiety-like behaviors and mitochondrial dysfunction in mice with targeted mutation of the Bcl-2 gene: further support for the involvement of mitochondrial function in anxiety disorders.

  2005influential reference
• Anxiolytic-like effects of ginseng in the elevated plus-maze model: comparison of red ginseng and sun ginseng.

  2005cited by this paper
• Anxiolytic-like effects of ginsenosides on the elevated plus-maze model in mice.

  2005cited by this paper
• Chapter 5.7 – Enhancing resilience to stress: the role of signaling cascades

  2005cited by this paper
• Neuroprotective Effect of Ginseng Total Saponins in Experimental Traumatic Brain Injury

  2005cited by this paper
• AR-A 014418 , a selective GSK-3 inhibitor , produces antidepressant-like effects in the forced swim test

  2004cited by this paper
• Ginsenoside Rh2 reduces ischemic brain injury in rats.

  2004influential reference
• AR-A014418, a selective GSK-3 inhibitor, produces antidepressant-like effects in the forced swim test.

  2004cited by this paper
• Ginsenosides Rb1 and Rg1 effects on mesencephalic dopaminergic cells stressed with glutamate.

  2004cited by this paper
• Protective effect of ginseng extract against apoptotic cell death induced by 2,2',5,5'-tetrachlorobiphenyl in neuronal SK-N-MC cells.

  2004cited by this paper
• Ginsenosides Rb1 and Rg1 effects on survival and neurite growth of MPP+-affected mesencephalic dopaminergic cells

  2004cited by this paper
• Mood stabilizers: protecting the mood...protecting the brain.

  2004cited by this paper
• The Role of the Extracellular Signal-Regulated Kinase Signaling Pathway in Mood Modulation

  2003cited by this paper
• MinireviewFinding the Intracellular Signaling Pathways Affected by Mood Disorder Treatments

  2003cited by this paper
• Enhancing neuronal plasticity and cellular resilience to develop novel, improved therapeutics for difficult-to-treat depression.

  2003cited by this paper
• Protective effects of pseudoginsenoside-F11 on methamphetamine-induced neurotoxicity in mice.

  2003cited by this paper
• Effects of ginseng saponin administered intraperitoneally on the hypothalamo-pituitary-adrenal axis in mice.

  2003cited by this paper
• Neuroprotective actions of the ginseng extract G115 in two rodent models of Parkinson's disease.

  2003influential reference
• New approaches to modeling bipolar disorder.

  2003cited by this paper
• Ginsenoside F1 protects human HaCaT keratinocytes from ultraviolet-B-induced apoptosis by maintaining constant levels of Bcl-2.

  2003cited by this paper
• Behavioral profile of rats submitted to session 1-session 2 in the elevated plus-maze during diurnal/nocturnal phases and under different illumination conditions.

  2002cited by this paper
• Preclinical models: status of basic research in depression.

  2002cited by this paper
• Pathophysiology of depression: the concept of synaptic plasticity

  2002cited by this paper
• Intra- and interstrain differences in models of "behavioral despair".

  2001cited by this paper
• The antidepressant activity of inositol in the forced swim test involves 5-HT(2) receptors.

  2001cited by this paper
• Neurotrophic and Neuroprotective Actions of Ginsenosides Rb1 and Rg1

  2001influential reference
• Inositol reduces depressive-like behaviors in two different animal models of depression

  1999cited by this paper
• Dietary supplements and natural products as psychotherapeutic agents.

  1999cited by this paper
• Behavioral phenotyping of transgenic and knockout mice: experimental design and evaluation of general health, sensory functions, motor abilities, and specific behavioral tests.

  1999cited by this paper
• High-performance liquid chromatographic analysis of ginseng saponins using evaporative light scattering detection

  1996cited by this paper
• Inositol treatment in psychiatry.

  1995cited by this paper
• Animal models of depression: validity and applications.

  1995cited by this paper
• Synopsis of Psychiatry.

  1992cited by this paper
• Goodman & Gilman's The Pharmacological Basis of Therapeutics

  1985cited by this paper
• Behavioral despair in mice: a primary screening test for antidepressants.

  1977cited by this paper

• UTILIZAÇÃO DE PANAX GINSENG EM CÃES E GATOS

  2022cites this paper
• Preventive Effect of Mebicar and Ginsenoside Rg1 on Neurobehavioral and Immunological Disruptions Caused by Intermittent Unpredictable Stress in Mice

  2018cites this paper
• Neuropharmacological Evaluation of the Ethanol Roots Extract of Securidacalonge pedunculata (Polygalaceae) in Mice

  2018cites this paper
• Use of Ginseng in Animal Production

  2017cites this paper
• Effects of Ginsomin ® on Selected Behaviours in Mice

  2017cites this paper
• Neuroprotective effect of water extract of Panax ginseng on corticosterone-induced apoptosis in PC12 cells and its underlying molecule mechanisms.

  2015cites this paper
• Ginseng Total Saponins Reverse Corticosterone-Induced Changes in Depression-Like Behavior and Hippocampal Plasticity-Related Proteins by Interfering with GSK-3β-CREB Signaling Pathway

  2014influential citation
• A comprehensive review of the therapeutic and pharmacological effects of ginseng and ginsenosides in central nervous system

  2013cites this paper
• UNIVERSIDADE FEDERAL DA PARAÍBA CENTRO DE CIÊNCIAS DA SAÚDE LABORATÓRIO DE TECNOLOGIA FARMACÊUTICA PROGRAMA DE PÓS-GRADUAÇÃO EM PRODUTOS NATURAIS E SINTÉTICOS BIOATIVOS

  2011cites this paper
• Effects of Sweet Bee Venom on the Central Nervous System in Rats: Use of a Functional Observational Battery

  2011cites this paper
• Identification of antidepressant-like ingredients in ginseng root (Panax ginseng C.A. Meyer) using a menopausal depressive-like state in female mice: participation of 5-HT2A receptors

  2011cites this paper
• The antidepressant effects and mechanism of action of total saponins from the caudexes and leaves of Panax notoginseng in animal models of depression.

  2011cites this paper
• Clinical Effects of Korean Red Ginseng on Attention Deficit Hyperactivity Disorder in Children: An Observational Study

  2011cites this paper
• Avanços no Estudo da Atividade Ansiolítica do Panax ginseng C. A. Meyer

  2011cites this paper
• Antidepressant-like effects of the active acidic polysaccharide portion of ginseng in mice.

  2010cites this paper
• Recent advances in the use of Panax ginseng as an analgesic: a systematic review

  2009cites this paper
• Mice Models for the Manic Pole of Bipolar Disorder

  2009cites this paper
• Anticonvulsant properties of saponins from Ficus platyphylla stem bark.

  2009cites this paper
• Antidepressant effects of ginseng total saponins in the forced swimming test and chronic mild stress models of depression.

  2009influential citation
• A possible utilization of the mice forced swim test for modeling manic-like increase in vigor and goal-directed behavior.

  2009cites this paper
• Recent advances in the use of Panax ginseng as an analgesic: a systematic review (Recientes avances del uso del Panax ginseng como analgésico: una revisión sistemática)

  2009cites this paper
• 20(S)-protopanaxadiol and the ginsenoside Rh2 inhibit Na+ channel-activated depolarization and Na+ channel-dependent amino acid neurotransmitter release in synaptic fractions isolated from mammalian brain.

  2008cites this paper
• Complementary medicine for psychiatric disorders in children and adolescents

  2008cites this paper
• Antidepressive-like effects of rapamycin in animal models: Implications for mTOR inhibition as a new target for treatment of affective disorders.

  2008cites this paper
• Psychopharmacological properties of the saponin fraction of Ficus platyphylla stem bark

  2008cites this paper
• Behavioral effects of Bcl-2 deficiency: implications for affective disorders.

  2008cites this paper