Stealth Liposomes in Human Welfare: An Overview

Liposomes are artificially made vesicles which has a lipid bilayer and can be used as a drug carrier molecule for the treatment of various cancers and other diseases. Conventional liposomes have short half-life because of rapid uptake by reticuloendothelial system which leads to decrease in the concentration of liposomes and drug efficacy. Liposomes when coated with polyethylene glycol leads to decreased uptake by the macrophages. This is called as stealth effect which prolongs the half-life of liposome in the circulation and in turn improves drug effectiveness. The liposomes coated with polyethylene glycol are also called as sterically stabilized liposomes or stealth liposomes. This review focuses on the characteristics, methods of preparation, applications, advantages and limitations of stealth liposomes.

• Publication year

  2022

• Venue

  International journal of pharmaceutical sciences review and research

• Publication date

  2022-01-15

• Fields of study

  Not labeled

• Identifiers
  DOI 10.47583/ijpsrr.2022.v72i01.003
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

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