CTLA‐4 polymorphism contributes to the genetic susceptibility of epithelial ovarian cancer

Juan Chen,Shan Kang,Jianlei Wu,Wengang Si,Haiyan Sun,Yan Li

Published 2022 in The journal of obstetrics and gynaecology research

ABSTRACT

Cytotoxic T‐lymphocyte antigen‐4 (CTLA‐4), an inhibitory molecule on T‐cells, plays a key role in tumorigenesis and progression. In the present study, we investigated the effects of three polymorphisms in the CTLA‐4 gene on the risk of epithelial ovarian cancer and the clinical outcomes of patients.

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