Latest Research Progress of the Pathogenesis of Depression and Its Status of TCM Treatment

Depressive disorder (DD) is one of the most common mental disorders and one of the main causes of disability in the world. Chronic or early life stress events are one of the main factors of DD. Recent studies have shown that the microbiota-gut-brain axis imbalance, the abnormal electrical activity of lateral habenula, and genetic variation are closely related to DD. Especially, in recent years, the emergence of the microbiota-gut-brain axis has attracted extensive attention. At present, the existing antidepressants and the therapeutic effect is not obvious even invalid for many patients, and it is likely to cause adverse effects. Traditional Chinese Medicine has obvious therapeutic effects, which are safe, reliable, low price, and significantly reduced the use of western medicine and its side effects. Therefore, traditional Chinese medicine and its therapeutic method gradually are applied to the clinical treatment of DD and achieved good results. The article summarizes the latest pathogenesis of DD and reviewed the mechanism of traditional Chinese medicine participating in DD treatment, to provide a reference for the clinical treatment of depression.

• Publication year

  2022

• Venue

  International Journal of Clinical and Experimental Medicine Research

• Publication date

  2022-02-10

• Fields of study

  Not labeled

• Identifiers
  DOI 10.26855/ijcemr.2022.01.016
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

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