Experimental Evolution in Tetrahymena

Experimental evolution has provided novel insight into a wide array of biological processes. Species in the genus Tetrahymena are proving to be a highly useful system for studying a range of questions using experimental evolution. Their unusual genomic architecture, diversity of life history traits, importance as both predator and prey, and amenability to laboratory culture allow them to be studied in a variety of contexts. In this paper, we review what we are learning from experimental evolution with Tetrahymena about mutation, adaptation, and eco-evolutionary dynamics. We predict that future experimental evolution studies using Tetrahyemena will continue to shed new light on these processes.

• Publication year

  2022

• Venue

  Microorganisms

• Publication date

  2022-02-01

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.3390/microorganisms10020414PMID 35208869PMCID 8877770
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Sex, amitosis, and evolvability in the ciliate Tetrahymena thermophila

  2021influential reference
• Identification and Characterization of Base-Substitution Mutations in the Macronuclear Genome of the Ciliate Tetrahymena thermophila.

  2021cited by this paper
• The completed macronuclear genome of a model ciliate Tetrahymena thermophila and its application in genome scrambling and copy number analyses

  2020cited by this paper
• Importance of protozoa Tetrahymena in toxicological studies: A review.

  2020cited by this paper
• Drivers of Mating Type Composition in Tetrahymena thermophila

  2020cited by this paper
• Temperature affects the repeatability of evolution in the microbial eukaryote Tetrahymena thermophila

  2020cited by this paper
• Identification and Characterization of Base-Substitution Mutations in the Macronuclear Genome of the Ciliate Tetrahymena thermophila

  2020cited by this paper
• Evolution under pH stress and high population densities leads to increased density‐dependent fitness in the protist Tetrahymena thermophila

  2020cited by this paper
• Predator coevolution and prey trait variability determine species coexistence

  2019cited by this paper
• Amitosis confers benefits of sex in the absence of sex to Tetrahymena

  2019cited by this paper
• Gene swamping alters evolution during range expansions in the protist Tetrahymena thermophila

  2019cited by this paper
• Genome plasticity in response to stress in Tetrahymena thermophila: selective and reversible chromosome amplification and paralogous expansion of metallothionein genes

  2018cited by this paper
• Dual-stressor selection alters eco-evolutionary dynamics in experimental communities

  2018cited by this paper
• Extreme metal adapted, knockout and knockdown strains reveal a coordinated gene expression among different Tetrahymena thermophila metallothionein isoforms

  2017cited by this paper
• Information use shapes the dynamics of range expansions into environmental gradients

  2017cited by this paper
• Eco-evolutionary dynamics

  2016cited by this paper
• Tetrahymena as a Unicellular Model Eukaryote: Genetic and Genomic Tools

  2016cited by this paper
• Structure of the germline genome of Tetrahymena thermophila and relationship to the massively rearranged somatic genome

  2016cited by this paper
• Low Base-Substitution Mutation Rate in the Germline Genome of the Ciliate Tetrahymena thermophila

  2015cited by this paper
• Eco-evolutionary feedbacks during experimental range expansions

  2015cited by this paper
• Protist predation can select for bacteria with lowered susceptibility to infection by lytic phages

  2015cited by this paper
• Quantitative evolutionary dynamics using high-resolution lineage tracking

  2015cited by this paper
• Environmental fluctuations restrict eco-evolutionary dynamics in predator–prey system

  2015cited by this paper
• Sustained fitness gains and variability in fitness trajectories in the long-term evolution experiment with Escherichia coli

  2015cited by this paper
• Relative importance of evolutionary dynamics depends on the composition of microbial predator–prey community

  2015cited by this paper
• DISPERSAL PROPENSITY IN TETRAHYMENA THERMOPHILA CILIATES—A REACTION NORM PERSPECTIVE

  2014cited by this paper
• Abandoning sex: multiple origins of asexuality in the ciliate Tetrahymena

  2014cited by this paper
• Rapid prey evolution can alter the structure of predator–prey communities

  2014cited by this paper
• Consumer co-evolution as an important component of the eco-evolutionary feedback

  2014cited by this paper
• RNA‐mediated genome rearrangement: Hypotheses and evidence

  2013influential reference
• Accumulation of Spontaneous Mutations in the Ciliate Tetrahymena thermophila

  2013influential reference
• Experimental evolution.

  2012cited by this paper
• Extraordinary genome stability in the ciliate Paramecium tetraurelia

  2012cited by this paper
• Drift-barrier hypothesis and mutation-rate evolution

  2012cited by this paper
• Tetrahymena in the laboratory: strain resources, methods for culture, maintenance, and storage.

  2012influential reference
• The life and times of Tetrahymena.

  2012cited by this paper
• Predation and resource fluctuations drive eco-evolutionary dynamics of a bacterial community

  2012cited by this paper
• Pulsed-Resource Dynamics Constrain the Evolution of Predator-Prey Interactions

  2011cited by this paper
• Mutation accumulation in Tetrahymena

  2010cited by this paper
• Spontaneous Mutation Accumulation Studies in Evolutionary Genetics

  2009cited by this paper
• Rapid diversification of mating systems in ciliates

  2009cited by this paper
• Availability of prey resources drives evolution of predator–prey interaction

  2008cited by this paper
• RNA-mediated epigenetic programming of a genome-rearrangement pathway

  2008influential reference
• Host race formation in the Acari

  2007cited by this paper
• Macronuclear Genome Sequence of the Ciliate Tetrahymena thermophila, a Model Eukaryote

  2006cited by this paper
• Significance of predation by protists in aquatic microbial food webs

  2004cited by this paper
• EVOLUTION OF HSP90 EXPRESSION IN TETRAHYMENA THERMOPHILA (PROTOZOA, CILIATA) POPULATIONS EXPOSED TO THERMALLY VARIABLE ENVIRONMENTS

  2004cited by this paper
• Evolution of Tetrahymena ribozyme mutants with increased structural stability

  2002cited by this paper
• PERSPECTIVE: SEX, RECOMBINATION, AND THE EFFICACY OF SELECTION—WAS WEISMANN RIGHT?

  2000cited by this paper
• EVOLUTIONARY ADAPTATION TO TEMPERATURE. IV. ADAPTATION OF ESCHERICHIA COLI AT A NICHE BOUNDARY

  1996cited by this paper
• MUTATIONAL MELTDOWNS IN SEXUAL POPULATIONS

  1995cited by this paper
• High frequency of sex and equal frequencies of mating types in natural populations of the ciliate Tetrahymena thermophila.

  1995cited by this paper
• The DNA of ciliated protozoa

  1994cited by this paper
• The distribution of mutation effects on viability in Drosophila melanogaster.

  1994cited by this paper
• EVOLUTIONARY ADAPTATION TO TEMPERATURE II. THERMAL NICHES OF EXPERIMENTAL LINES OF ESCHERICHIA COLI

  1993cited by this paper
• Rate of phenotypic assortment in Tetrahymena thermophila.

  1992cited by this paper
• Long-Term Experimental Evolution in Escherichia coli. I. Adaptation and Divergence During 2,000 Generations

  1991cited by this paper
• Long-term experimental evolution in Escherichia coli

  1991cited by this paper
• Tetrahymena. Adaptation to high iron.

  1984cited by this paper
• Membrane changes during growth of Tetrahymena in the presence of ethanol.

  1979cited by this paper
• Changes in membrane lipid composition during temperature adaptation by a thermotolerant strain of Tetrahymena pyriformis.

  1976cited by this paper
• THE ADAPTATION OF TETRAHYMENA TO A HIGH NaCl ENVIRONMENT

  1964cited by this paper
• THE GENETIC STRUCTURE OF NATURAL POPULATIONS OF DROSOPHILA MELANOGASTER. I. SPONTANEOUS MUTATION RATE OF POLYGENES CONTROLLING VIABILITY.

  1964cited by this paper
• THE VIABILITY OF NEAR-NORMAL IRRADIATED CHROMOSOMES

  1959cited by this paper
• Caryonidal Inheritance and Nuclear Differentiation

  1956cited by this paper

• Temperature stress disrupts reciprocal adaptation in a microbial predator-prey system

  2025cites this paper
• Thermal response of freshwater ciliates: Can they survive at elevated lake temperatures?

  2024cites this paper
• Protists and protistology in the Anthropocene: challenges for a climate and ecological crisis

  2024cites this paper
• Experimental evolution for cell biology.

  2023cites this paper
• Localized coevolution between microbial predator and prey alters community-wide gene expression and ecosystem function

  2022cites this paper