v-Rel and c-Rel are differentially affected by mutations at a consensus protein kinase recognition sequence.

No abstract is available for this paper.

• Publication year

  1993

• Venue

  Oncogene

• Publication date

  1993-03-01

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 8437855
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Transcriptional activity of rel family proteins.

  1992cited by this paper
• RelB, a new Rel family transcription activator that can interact with p50-NF-kappa B

  1992cited by this paper
• The C terminus of the NF-kappa B p50 precursor and an I kappa B isoform contain transcription activation domains.

  1992cited by this paper
• Role of rel family genes in normal and malignant lymphoid cell growth.

  1992cited by this paper
• The RxxRxRxxC motif conserved in all Rel/kappa B proteins is essential for the DNA-binding activity and redox regulation of the v-Rel oncoprotein

  1992cited by this paper
• A novel mitogen-inducible gene product related to p50/p105-NF-kappa B participates in transactivation through a kappa B site

  1992cited by this paper
• The functional domains of the Drosophila morphogen dorsal: evidence from the analysis of mutants.

  1992cited by this paper
• I-Rel: a novel rel-related protein that inhibits NF-kappa B transcriptional activity.

  1992cited by this paper
• The v-rel oncogene: insights into the mechanism of transcriptional activation, repression, and transformation

  1992cited by this paper
• p105, the NF-kappa B p50 precursor protein, is one of the cellular proteins complexed with the v-Rel oncoprotein in transformed chicken spleen cells

  1992cited by this paper
• Malignant transformation by mutant Rel proteins.

  1991cited by this paper
• Inhibition of transcription factors belonging to the rel/NF‐kappa B family by a transdominant negative mutant.

  1991cited by this paper
• Expression of a mRNA related to c-rel and dorsal in early Xenopus laevis embryos.

  1991cited by this paper
• Cloning of an NF-kappa B subunit which stimulates HIV transcription in synergy with p65.

  1991cited by this paper
• Repression of the chicken c-rel promoter by vRel in chicken embryo fibroblasts is not mediated through a consensus NF-kappa B binding site.

  1991cited by this paper
• A protein kinase-A recognition sequence is structurally linked to transformation by p59v-rel and cytoplasmic retention of p68c-rel

  1991cited by this paper
• The inducible transcription activator NF-kappa B: regulation by distinct protein subunits.

  1991cited by this paper
• vRel is an inactive member of the Rel family of transcriptional activating proteins

  1991cited by this paper
• Isolation of a rel-related human cDNA that potentially encodes the 65-kD subunit of NF-kappa B.

  1991cited by this paper
• A yeast transcription assay defines distinct rel and dorsal DNA recognition sequences.

  1991cited by this paper
• DNA binding and I kappa B inhibition of the cloned p65 subunit of NF-kappa B, a rel-related polypeptide.

  1991cited by this paper
• c-rel activates but v-rel suppresses transcription from kappa B sites.

  1991cited by this paper
• Mutational analysis of v-rel, the oncogene of reticuloendotheliosis virus strain T.

  1990cited by this paper
• NF-kappa B, KBF1, dorsal, and related matters.

  1990cited by this paper
• The v-rel oncogene encodes a kappa B enhancer binding protein that inhibits NF-kappa B function.

  1990cited by this paper
• Oncogenic transformation by vrel requires an amino-terminal activation domain

  1990cited by this paper
• Cloning and expression of a chicken c-rel cDNA: unlike p59v-rel, p68c-rel is a cytoplasmic protein in chicken embryo fibroblasts.

  1990cited by this paper
• The mouse c-rel protein has an N-terminal regulatory domain and a C-terminal transcriptional transactivation domain

  1990cited by this paper
• A human rel proto-oncogene cDNA containing an Alu fragment as a potential coding exon.

  1989cited by this paper
• Transactivation of gene expression by nuclear and cytoplasmic rel proteins

  1989cited by this paper
• I kappa B: a specific inhibitor of the NF-kappa B transcription factor.

  1988cited by this paper
• Detection and characterization of the protein encoded by the chicken c-rel protooncogene.

  1988cited by this paper
• Dorsal, an embryonic polarity gene in Drosophila, is homologous to the vertebrate proto-oncogene, c-rel.

  1987cited by this paper
• Activation of oncogenicity of the c-rel proto-oncogene

  1986cited by this paper
• Synthetic peptides corresponding to the site phosphorylated in 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase as substrates of cyclic nucleotide-dependent protein kinases.

  1986cited by this paper
• Different localization of the product of the v-rel oncogene in chicken fibroblasts and spleen cells correlates with transformation by REV-T.

  1986cited by this paper
• Rapid and efficient site-specific mutagenesis without phenotypic selection.

  1985cited by this paper
• Nucleic acid sequences of the oncogene v-rel in reticuloendotheliosis virus strain T and its cellular homolog, the proto-oncogene c-rel

  1984cited by this paper
• Nucleotide sequence of v-rel: the oncogene of reticuloendotheliosis virus.

  1983cited by this paper
• Construction of a helper cell line for avian reticuloendotheliosis virus cloning vectors

  1983cited by this paper

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• Roles of c-Rel signalling in inflammation and disease.

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• of c-Rel and v-Rel by distinct mechanisms. I(kappa)B-alpha regulates cellular localization by I(kappa)B-alpha: evidence that PEST-dependent cytoplasmic retention of v-Rel

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• NF-kappaB inhibitors for the treatment of inflammatory diseases and cancer.

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• Nuclear factor-kappaB: activation and regulation during toll-like receptor signaling.

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• Nuclear Factor-κ B : Activation and Regulation during Toll-Like Receptor Signaling

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• Regulation of Nuclear NF-_B Action: A Key Role for Posttranslational Modification

  2006cites this paper
• Genetic Analysis of Growth Inhibition by GAL 4-IKB-o . . in Saccharomyces cerevisiae

  2005cites this paper
• Shaping the nuclear action of NF-κB

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• The Rel/NF-κB/IκB Signal Transduction Pathway and Cancer

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• Shaping the nuclear action of NF-kappaB.

  2004cites this paper
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  2004cites this paper
• IκB Kinase-Independent IκBα Degradation Pathway: Functional NF-κB Activity and Implications for Cancer Therapy

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• Viruses as Intruders in the Rel/NF-κB Signaling Pathway

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• New Insights into the Regulation of Nf-кB

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• Putting the Brake on Inflammatory Responses: the Role of Glucocorticoids

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• Mutations within a conserved protein kinase A recognition sequence confer temperature-sensitive and partially defective activities onto mouse c-Rel.

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• Distinct Pathways for NF-κB Regulation Are Associated with Aberrant Macrophage IL-12 Production in Lupus- and Diabetes-Prone Mouse Strains1

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• ReviewMissing Pieces in the NF-B Puzzle stimulate the migration and maturation of lymphocytes

  2002influential citation
• Mutational Analysis of the v-Rel Dimerization Interface Reveals a Critical Role for v-Rel Homodimers in Transformation

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• The chicken RelB transcription factor has transactivation sequences and a tissue-specific expression pattern that are distinct from mammalian RelB.

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• Three mutations in v-Rel render it resistant to cleavage by cell-death protease caspase-3.

  2001cites this paper
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  1999cites this paper
• The NF-kappaB/Rel family of transcription factors in oncogenic transformation and apoptosis.

  1999cites this paper
• Mapping of a Serine-Rich Domain Essential for the Transcriptional, Antiapoptotic, and Transforming Activities of the v-Rel Oncoprotein

  1999cites this paper
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  1998cites this paper
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  1998cites this paper
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  1997cites this paper
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  1997cites this paper
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  1997cites this paper
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  1997cites this paper
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  1996cites this paper
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  1996cites this paper
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  1996cites this paper
• Elevated Cyclic AMP Inhibits NF-κB-mediated Transcription in Human Monocytic Cells and Endothelial Cells*

  1996cites this paper
• Bcl-2 and CrmA have different effects on transformation, apoptosis and the stability of I kappa B-alpha in chicken spleen cells transformed by temperature-sensitive v-Rel oncoproteins.

  1996cites this paper
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  1996cites this paper
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  1995cites this paper
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  1995cites this paper
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  1995cites this paper
• Genetic Analysis of Growth Inhibition by GAL4-IKB-o

  1995cites this paper
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  1994cites this paper
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• Effect of CD28 signal transduction on c-Rel in human peripheral blood T cells

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• Interaction of the v-Rel oncoprotein with cellular transcription factor Sp1

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• CHAPTER 12 – Hormonally Regulated Transcription Factors

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  1993cites this paper
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  1993cites this paper
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• NF-kappa B p100 is one of the high-molecular-weight proteins complexed with the v-Rel oncoprotein in transformed chicken spleen cells

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• Temperature-sensitive transforming mutants of the v-rel oncogene

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