Lipins from plants are phosphatidate phosphatases that restore lipid synthesis in a pah1Δ mutant strain of Saccharomyces cerevisiae

No abstract is available for this paper.

• Publication year

  2011

• Venue

  The FEBS Journal

• Publication date

  2011-03-01

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1111/j.1742-4658.2010.07995.xPMID 21205207
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• PHOSPHATIDIC ACID PHOSPHOHYDROLASE1 and 2 Regulate Phospholipid Synthesis at the Endoplasmic Reticulum in Arabidopsis[W]

  2010cited by this paper
• Characterization of the Human LPIN1-encoded Phosphatidate Phosphatase Isoforms*

  2010cited by this paper
• A Conserved Serine Residue Is Required for the Phosphatidate Phosphatase Activity but Not the Transcriptional Coactivator Functions of Lipin-1 and Lipin-2*

  2009cited by this paper
• Lipins, Lipids and Nuclear Envelope Structure

  2009cited by this paper
• Phosphatidic Acid Phosphatase, a Key Enzyme in the Regulation of Lipid Synthesis*

  2009cited by this paper
• Arabidopsis lipins mediate eukaryotic pathway of lipid metabolism and cope critically with phosphate starvation

  2009cited by this paper
• Lipid phosphate phosphatases and signaling The work was supported by the Canadian Institutes of Health Research. Published, JLR Papers in Press, December 9, 2008.

  2009cited by this paper
• Temporal and Spatial Regulation of the Phosphatidate Phosphatases Lipin 1 and 2

  2008cited by this paper
• The lipin protein family: Dual roles in lipid biosynthesis and gene expression

  2008cited by this paper
• Multiple roles for lipins/phosphatidate phosphatase enzymes in lipid metabolism

  2008cited by this paper
• The Cellular Functions of the Yeast Lipin Homolog Pah1p Are Dependent on Its Phosphatidate Phosphatase Activity*

  2007cited by this paper
• Cloning and functional characterization of the fatty acid elongase 1 (FAE1) gene from high erucic Crambe abyssinica cv. Prophet.

  2007cited by this paper
• Insulin Controls Subcellular Localization and Multisite Phosphorylation of the Phosphatidic Acid Phosphatase, Lipin 1*

  2007cited by this paper
• Plastidic Phosphatidic Acid Phosphatases Identified in a Distinct Subfamily of Lipid Phosphate Phosphatases with Prokaryotic Origin*

  2007cited by this paper
• Phosphatidic Acid Plays a Central Role in the Transcriptional Regulation of Glycerophospholipid Synthesis in Saccharomyces cerevisiae*

  2007cited by this paper
• Diacylglycerol, when simplicity becomes complex.

  2007cited by this paper
• The Saccharomyces cerevisiae Lipin Homolog Is a Mg2+-dependent Phosphatidate Phosphatase Enzyme*♦

  2006cited by this paper
• Control of Phospholipid Synthesis by Phosphorylation of the Yeast Lipin Pah1p/Smp2p Mg2+-dependent Phosphatidate Phosphatase*

  2006cited by this paper
• Roles of phosphatidate phosphatase enzymes in lipid metabolism.

  2006cited by this paper
• Lipin 1 is an inducible amplifier of the hepatic PGC-1alpha/PPARalpha regulatory pathway.

  2006cited by this paper
• Lipin 1 is an inducible amplifier of the hepatic PGC-1α/PPARα regulatory pathway

  2006cited by this paper
• Faculty Opinions recommendation of Genome-wide identification and testing of superior reference genes for transcript normalization in Arabidopsis.

  2006cited by this paper
• The yeast lipin Smp2 couples phospholipid biosynthesis to nuclear membrane growth

  2005cited by this paper
• Genome-Wide Identification and Testing of Superior Reference Genes for Transcript Normalization in Arabidopsis1[w]

  2005cited by this paper
• Lipid phosphate phosphatases and related proteins: Signaling functions in development, cell division, and cancer

  2004cited by this paper
• Global analysis of protein localization in budding yeast

  2003cited by this paper
• Molecular Cloning: A Laboratory Manual

  2001cited by this paper
• Lipid Phosphate Phosphatases in Arabidopsis

  2001cited by this paper
• Lipodystrophy in the fld mouse results from mutation of a new gene encoding a nuclear protein, lipin

  2001cited by this paper
• Phosphatidic acid, a key intermediate in lipid metabolism.

  1999cited by this paper
• A New Class of Phosphotransferases Phosphorylated on an Aspartate Residue in an Amino-terminal DXDX(T/V) Motif*

  1998cited by this paper
• Phosphatidate phosphatase from avocado (Persea americana) – purification, substrate specificity and possible metabolic implications for the Kennedy pathway and cell signalling in plants

  1998cited by this paper
• Mammalian Lipid Phosphate Phosphohydrolases*

  1998cited by this paper
• Phosphatidate phosphatases and diacylglycerol pyrophosphate phosphatases in Saccharomyces cerevisiae and Escherichia coli.

  1997cited by this paper
• Identification of a novel phosphatase sequence motif

  1997cited by this paper
• Phosphatidate phosphatase from developing seeds and microspore-derived cultures of Brassica napus

  1996cited by this paper
• Phosphatidate phosphatases of mammals, yeast, and higher plants

  1996cited by this paper
• Effects of okadaic acid on the activities of two distinct phosphatidate phosphohydrolases in rat hepatocytes

  1992cited by this paper
• Phosphatidate phosphohydrolases in liver, heart and adipose tissue of the JCR:LA corpulent rat and the lean genotypes: implications for glycerolipid synthesis and signal transduction.

  1992cited by this paper
• Plasma membrane fractions from rat liver contain a phosphatidate phosphohydrolase distinct from that in the endoplasmic reticulum and cytosol.

  1991cited by this paper
• Characterization and assay of phosphatidate phosphatase.

  1991cited by this paper
• Intracellular translocation of phosphatidate phosphatase in maturing safflower seeds: a possible mechanism of feedforward control of triacylglycerol synthesis by fatty acids.

  1990cited by this paper
• Oleic acid promotes the activation and translocation of phosphatidate phosphohydrolase from the cytosol to particulate fractions of isolated rat hepatocytes.

  1984cited by this paper
• A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding.

  1976cited by this paper
• A rapid method of total lipid extraction and purification.

  1959cited by this paper

• Comprehensive analysis of proteins associated with light responses and stress tolerance in the gametophyte of the fern Dryopteris affinis ssp. affinis

  2025cites this paper
• PfPAH1-1 gene enhances plant tolerance to low phosphate stress by modulating cell membrane lipid remodeling.

  2025cites this paper
• Chloroplast phosphatases LPPγ and LPPε1 facilitate conversion of extraplastidic phospholipids to galactolipids.

  2024cites this paper
• The antidepressant drug sertraline is a novel inhibitor of yeast Pah1 and human lipin 1 phosphatidic acid phosphatases

  2024cites this paper
• Heat shock factor ZmHsf17 positively regulates phosphatidic acid phosphohydrolase ZmPAH1 and enhances maize thermotolerance

  2024cites this paper
• The Plasma Membrane H+-ATPase Promoter Driving the Expression of FADX Enables Highly Efficient Production of Punicic Acid in Rhodotorula toruloides Cultivated on Glucose and Crude Glycerol

  2024influential citation
• Nitrogen availability is important for preventing catastrophic mitosis in fission yeast.

  2024cites this paper
• Heterologous Production of Calendic Acid Naturally Found in Calendula officinalis by Recombinant Fission Yeast.

  2023cites this paper
• Dynamic Regulation of Lipid Droplet Biogenesis in Plant Cells and Proteins Involved in the Process

  2023cites this paper
• Phosphatidic acid phosphohydrolase modulates glycerolipid synthesis in Marchantia polymorpha and is crucial for growth under both nutrient-replete and -deficient conditions

  2023influential citation
• Acyl-CoA:diacylglycerol acyltransferase: Properties, physiological roles, metabolic engineering and intentional control.

  2022cites this paper
• Interactions between plant lipid-binding proteins and their ligands.

  2022cites this paper
• Development and application of novel InDel markers in flax (Linum usitatissimum L.) through whole-genome re-sequencing

  2021cites this paper
• The Aquila Digital Community The Aquila Digital Community Phospholipase D ζ Enhances Diacylglycerol Flux Into Phospholipase D Enhances Diacylglycerol Flux Into Triacylglycerol Triacylglycerol

  2020cites this paper
• Enzymes of glycerol-3-phosphate pathway in triacylglycerol synthesis in plants: Function, biotechnological application and evolution.

  2019cites this paper
• Cadmium accumulation capacity and resistance strategies of a cadmium-hypertolerant fern - Microsorum fortunei.

  2019cites this paper
• Mechanisms of lipid droplet biogenesis.

  2019cites this paper
• The Spatiotemporal Deposition of Lysophosphatidylcholine Within Starch Granules of Maize Endosperm and its Relationships to the Expression of Genes Involved in Endoplasmic Reticulum–Amyloplast Lipid Trafficking and Galactolipid Synthesis

  2018cites this paper
• Biochemical and structural characterisation of human phosphatidylinositol transfer protein Nir2 and American hookworm lipid binding protein Na-FAR-1

  2018cites this paper
• Host Pah1p phosphatidate phosphatase limits viral replication by regulating phospholipid synthesis

  2018cites this paper
• An evolutionarily conserved phosphatidate phosphatase maintains lipid droplet number and endoplasmic reticulum morphology but not nuclear morphology

  2017influential citation
• Importance of phosphatidylcholine on the chloroplast surface.

  2017cites this paper
• Metabolic engineering of Schizosaccharomyces pombe to produce punicic acid, a conjugated fatty acid with nutraceutic properties

  2017influential citation
• Phospholipase Dζ Enhances Diacylglycerol Flux into Triacylglycerol1[OPEN]

  2017cites this paper
• Cyclin‐dependent kinase activity enhances phosphatidylcholine biosynthesis in Arabidopsis by repressing phosphatidic acid phosphohydrolase activity

  2016cites this paper
• Arabidopsis GPAT9 contributes to synthesis of intracellular glycerolipids but not surface lipids

  2016cites this paper
• Understanding the control of acyl flux through the lipid metabolic network of plant oil biosynthesis.

  2016cites this paper
• Transcriptome profiling of Camelina sativa to identify genes involved in triacylglycerol biosynthesis and accumulation in the developing seeds

  2016cites this paper
• Lipid Metabolism in Microalgae

  2016cites this paper
• The Regulation of the Phosphatidate Phosphatase Gene PAH1 and Its Regulatory Role on Cell Homeostasis

  2016cites this paper
• PHOSPHATIDIC ACID PHOSPHOHYDROLASE Regulates Phosphatidylcholine Biosynthesis in Arabidopsis by Phosphatidic Acid-Mediated Activation of CTP:PHOSPHOCHOLINE CYTIDYLYLTRANSFERASE Activity[OPEN]

  2015influential citation
• Function of polar glycerolipids in flower development in Arabidopsis thaliana.

  2015cites this paper
• Heterologous expression of flax PHOSPHOLIPID:DIACYLGLYCEROL CHOLINEPHOSPHOTRANSFERASE (PDCT) increases polyunsaturated fatty acid content in yeast and Arabidopsis seeds

  2015cites this paper
• Combined transgenic expression of Punica granatum conjugase (FADX) and FAD2 desaturase in high linoleic acid Arabidopsis thaliana mutant leads to increased accumulation of punicic acid

  2014cites this paper
• Inactivation of the Host Lipin Gene Accelerates RNA Virus Replication through Viral Exploitation of the Expanded Endoplasmic Reticulum Membrane

  2014cites this paper
• Molecular characterisation of two homoeologous elicitor-responsive lipin genes in cotton

  2013cites this paper
• The phosphatidylinositol‐transfer protein Nir2 binds phosphatidic acid and positively regulates phosphoinositide signalling

  2013cites this paper
• Biotechnology of Crucifers

  2013cites this paper
• Phospholipid metabolism and nuclear function: roles of the lipin family of phosphatidic acid phosphatases.

  2013cites this paper
• Phosphate starvation and membrane lipid remodeling in seed plants.

  2013cites this paper
• Identification of a Pair of Phospholipid:Diacylglycerol Acyltransferases from Developing Flax (Linum usitatissimum L.) Seed Catalyzing the Selective Production of Trilinolenin*

  2013cites this paper
• Assaying plant phosphatidic acid phosphatase activity.

  2013cites this paper
• Genetic Engineering of Lipid Biosynthesis in Seeds

  2013cites this paper
• Lipid Phosphate Phosphatases and Signaling by Lysophospholipid Receptors

  2013cites this paper
• Regulation and Functions of Cardiac Lipins

  2012cites this paper
• TAG, you're it! Chlamydomonas as a reference organism for understanding algal triacylglycerol accumulation.

  2012cites this paper
• Purification, characterization, and bioinformatics studies of phosphatidic acid phosphohydrolase from Lagenaria siceraria

  2012cites this paper
• Thematic Review Series: Lipid Droplet Synthesis and Metabolism: from Yeast to Man Biogenesis and functions of lipid droplets in plants

  2012cites this paper
• Unlike two peas in a pod: lipid phosphate phosphatases and phosphatidate phosphatases.

  2012cites this paper
• Identification and characterization of an LCAT‐like Arabidopsis thaliana gene encoding a novel phospholipase A

  2012cites this paper
• Compartmentation of Triacylglycerol Accumulation in Plants*

  2011cites this paper
• The Aquila Digital Community The Aquila Digital Community

  year unknowncites this paper
• Phospholipase D ζ Enhances Diacylglycerol Flux into Phospholipase D Enhances Diacylglycerol Flux into Triacylglycerol Triacylglycerol

  year unknowncites this paper
• Genome-Wide Identification and Expression Analysis of Fatty Acid Desaturase ( FAD ) Genes in Camelina sativa (L.) Crantz

  year unknowncites this paper